Welcome to the Olink® Proteomics in Proximity podcast!
Below are some useful resources from this episode:
Published study of primary focus
Koprulu M, Carrasco-Zanini J, Wheeler E, Lockhart S, Kerrison ND, Wareham NJ, Pietzner M, Langenberg C. Proteogenomic links to human metabolic diseases. Nat Metab. 2023 Mar;5(3):516-528. doi: 10.1038/s42255-023-00753-7. Epub 2023 Feb 23. Erratum in: Nat Metab. 2023 Mar 19;: PMID: 36823471; PMCID: PMC7614946.
pubmed.ncbi.nlm.nih.gov/36823...
Laboratory, first author, and corresponding author of the study
• Public Health University Research Institute (PHURI), a multidisciplinary research center to drive personalized healthcare: www.qmul.ac.uk/phuri/about/
• Mine Koprulu (first author), PhD student, University of Cambridge: / mine-koprulu-497659b9
• Dr. Claudia Langenberg (corresponding author); Director of PHURI, Queen Mary, University of London; Professor of Computational Medicine, Berlin Institute of Health at Charité: www.qmul.ac.uk/phuri/our-peop...
Olink tools and software
• Olink® Explore 3072, the platform that measured proteins in this study with a next-generation sequencing (NGS) readout: olink.com/products-services/e...
UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, www.ukbiobank.ac.uk/learn-mor...
Genotype-Tissue Expression (GTEx) project, a biobank and open-access database to study tissue-specific gene expression and regulation: www.gtexportal.org/home/
European Prospective Investigation into Cancer (EPIC)-Norfolk study, a prospective cohort of middle-aged individuals from Eastern England: www.epic-norfolk.org.uk/
Genome Aggregation Database (gnomAD), the largest publicly available collection of population variation from harmonized exome and genome sequencing data: gnomad.broadinstitute.org/
Would you like to subscribe to the podcast on your favorite player or app? You can do so here:
Apple Podcasts: apple.co/3T0YbSm
Spotify Podcasts: open.spotify.com/show/2sZ2wxO...
Google Podcasts: podcasts.google.com/feed/aHR0...
Amazon Music: music.amazon.com/podcasts/d97...
Podcast Addict: podcastaddict.com/podcast/409...
Deezer: www.deezer.com/show/5178787
Player FM: player.fm/series/series-3396598
In case you were wondering, Proteomics in Proximity refers to the principle underlying Olink technology called the Proximity Extension Assay (PEA). More information about the assay and how it works can be found here: bit.ly/3Rt7YiY
For any questions regarding information Olink Proteomics, please email us at info@olink.com or visit our website: www.olink.com/
WHAT IS PROTEOMICS IN PROXIMITY?
Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Cindy Lawley and Sarantis Chlamydas.