CAR T Cell Routes of Administration explores the critical role of route of administration in CAR T cell therapy, examining regional administration's potential to overcome physical barriers, enhance tumor targeting, and minimize toxicities.
Key message: The choice of route of administration varies by disease and plays a role in the efficacy, safety, and outcomes of CAR T cell therapy. Different routes offer distinct advantages and limitations, influencing factors such as tumor targeting precision, tissue penetration, and systemic toxicity.
Learning Objective: Understand how different routes of administration impact the distribution, infiltration, and targeting of CAR T cells in the body, and the advantages and limitations of intravenous vs. regional administration routes.
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