No doubts, but all the more anticipation and hope for a better world with the help of great people like Dr. David Sinclair!🙌💫

David Sinclair is awesome.

I’m obsessed with Sinclair. What a dude.

Dr. Sinclair fascinates me, his work will change the world.

@acjshook

Жыл бұрын

For the rich. His company lobbied the FDA to have NMN supplements removed from the market due to their drug trials, so we can no longer get it as a supplement. I've been taking it for several months now and it really is a game changer, but because of this move will not be available for the average citizen for the forseeable future. When they release it as a drug, you can count on it being out of reach financially for most of us, especially before it's approved as a "treatment" by most insurance companies. I'm super grateful for his research, but incredibly bitter about this move, as NMN really makes a huge difference - especially when you're trying to regain muscle mass and retain bone density as an older person - and now we can't get it anymore.

@NemmieMK

Жыл бұрын

Honestly most people aren’t ready for what his work is going to do. I’m already on his bandwagon, though 😆

@WackyGameEngineer

10 ай бұрын

​@@NemmieMKme too 😂

@mag4926

10 ай бұрын

@@NemmieMK I fully agree with you! Most people are more ready for TikTok and Netflix.😅 For most people, what Sinclair says in the video is comparable to a group of people standing in front of a tree that is rustling its leaves. People hear but understand nothing as they only hear the rustling of the leaves.... Let's stay positive into the future because we are among the few people who are already ready!🙌💫

@laikiugarland1082

6 ай бұрын

@@mag4926 playboy sells lot better than electronic wor😂ld

Dr. Sinclair is right to point out that even a student can do what his lab is doing--it is quite simple.

Help him to help us I love you Sinclair! Lots of high hopes for us and ageing ...

I love David Sinclair. Research ❤ on anti aging.

Rooting for you, Dr. Sinclair. I lost my last functional Optic Nerve 2 years ago, and am living through hell now. All I see is bright light and fog. It's not even 'traditional blindness', it's something far worse imo.. I need the good Doctor here to succeed...

@Liberty309

Жыл бұрын

Start taking the NMN ,the good stuff, not the bs stuff they pettle everywhere. Also start using trans resveratrol as well. Do your research buy the high quality lab stuff.

@CujoHyer

Жыл бұрын

@@Liberty309 I'm using a Screen Reader just to be here. Haha. I can't find 'the good stuff'. I can barely find KZread, lol.

@hata6290

Жыл бұрын

@@CujoHyer youll make it friend

@squamish4244

9 ай бұрын

Cheering you on. Hopefully this is fast-tracked by the FDA to human trials. It's been shown to work so definitively, I can't see what would stop this.

@CujoHyer

9 ай бұрын

​@@squamish4244 Yeah, it sounds 'to good to be true', and whenever I tell people about it I can tell they don't believe me. It just comes off as the mad ramblings of a desperate broken person. But, who the heck knows. Thank you, though, I am a quietly desperate person to say the least.

He looks pretty young. I am also practicing intermittent fasting, and periodically exercising, too. Feeling very well.

I would appreciate a response to Dr. Charles Brenner's Article "Sirtuins are not conserved longevity genes" Life Metabolism, Volume 1, Issue 2, October 2022, Pages 122-133.

Have you been able to reverse hearing loss in mice? I have hearing loss in one of my ears and an awful shrilling tinnitus has taken it's place. I would love to see a reversal of hearing loss and perhaps the end to the tinnitus.

@cherylziervogel1779

Жыл бұрын

Try NMN ( it helps with mitochondrial function.) Give it time..about 3 to 6 months and see what happens. Best wishes!! 😊

@squamish4244

9 ай бұрын

Neurofeedback has been shown to be highly effective for tinnitus. Either by rewiring the brain so the tinnitus stops, or drastically reducing the rumination on the tinnitus, so you notice it far less. Or both. My father has severe tinnitus but he's a stubborn Boomer man and won't get any help for his health problems unless he thinks of it first. Or you trick him into making him think he thought of it first.

Why have two different interviews in two different topics at the same time? There were no debate or reasoning between them. Why not interview two very talented persons who are experts in the same field? That would be interesting. Now, none of them got the time or questioning they needed

Interesting

@hata6290

Жыл бұрын

you are stunning

. . . reset mice several times? That's news. I would imagine that means 3-4 times with diminishing returns. Effectively like 2.5x. Which would be fantastic--it would mean like a 30% improvement in lifespan.

@peterm5554

Жыл бұрын

The current OSK treatment that has been published to extend the age of old mice uses AAV to deliver the genes which results in I think much less than 50% of the cells getting the osk genes. Ideally 100% of the cells would get the OSK genes which should mean a lot more of the body gets younger. I think that’s what they are working on and I think I have heard/read David Sinclair day it’s difficult but not impossible

@peterm5554

Жыл бұрын

I should add that the current OSK gene delivery to treat a form of blindness in monkeys is quite effective and the electrical activity of the eye returned almost to baseline after the blind eye was treated

@sholovewilson1796

Жыл бұрын

I never knew I loved mouses so much...

_What_ is the lady doctor's name again?

@CelesMaria

Жыл бұрын

The woman in the middle is Dr. Deborah Persaud!

An injection or taking a pill for a couple of months to reverse age by more than a decade. I would like to know what’s in the injection. Is it gene therapy or natural/synthetic molecules?

@johnsmith813

Жыл бұрын

Dreams.

@peterm5554

Жыл бұрын

@@johnsmith813 You are allowed to change your mind when you see queues of people lining up to get their age reversal injection.

@templeray5754

Жыл бұрын

@@peterm5554 people like him like most of the population is not going to believe aging can be reversed tell that time comes.

@namehidden8854

Жыл бұрын

Viral vector delivery of OSK. I.e., gene therapy, yes.

@sholovewilson1796

Жыл бұрын

I can't wait Sinclair's a miracle to our longevity

Sadly we are moving toward a more violent world. I wonder how one would effectively treat an acute radiation sickness. It would be an extremely challenging task from a biochemical perspective. Perhaps the Yamanaka factors could be of some use though.

@sholovewilson1796

Жыл бұрын

Let's just hope for the best and a good outcome for our species in the end...hopefully radiation and war and all that stuff doesn't threaten us to much...

How is curing HIV equally important to curing blindness and reversing the affects of aging such and cancer and heart disease. Am I missing something?

@markobrien2241

Жыл бұрын

Aprox 8.30

@hata6290

Жыл бұрын

its the fault of the summit. im assuming theyve organized it like this due to "time constraints" however, i agree its unfair and awkward to have them both on the stage. like, her work is amazing, but its really hard to shine when you have the guy on the literal frontier of reversing human aging

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Жыл бұрын

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Жыл бұрын

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@eleanorchelsie6094

Жыл бұрын

< normandavis

David Sinclair aka The Wet Noodle

Scientists are still in the dark ages with regards to many diseases. Cancer should have been cured decades ago. As far as full age reversal goes, not likely going to happen in the next ten lifetimes. Been waiting over 20 years for the aging field to accomplish anything. Now that my family has mostly passed from Cancer, that Scientists can't cure, I don't care about living longer anymore. I hope people that care to live longer reap any benefits that come in the future. Time runs out very, very, very quickly.

@johnniejay

Жыл бұрын

I know where you're coming from - as someone who has followed this field very closely for 15 years or so, it is frustrating how slowly progress is being made. In some senses they'res been some extraordinary breakthroughs, but we still have nothing to really show for it as far as FDA approved therapies that reverse aging without a shadow of a doubt - and you're right, time goes incredibly quickly. I hope we're not looking back in another 20 or 30 years having made as little progress as the last 20. I am still somewhat optimistic however, only because I believe (or rather hope) that AI will be the gamechanger that we need - when drug discovery and personalized healthcare plans are taking months to formulate instead of decades, we'll have reached the inflection point. But yes, its deeply frustrating and frankly depressing how little we still know about healing and ultimately rejuvenating the human body. And yes, its inexcusable that after decades of research and literally trillions of dollars theres still no cure for cancer.

@vickybiagini8623

Жыл бұрын

@@johnniejay , You're exactly right, and at this point for me I don't care. I watch that man Brian on you tube that spent millions trying to reverse his aging. He goes through so much on a daily basis, and it seems like it's just not worth it. I really don't care much anymore, because I'm almost 50 waiting for these so called breakthroughs. Most of my family has passed already. Maybe young people will get these therapies. My body's tired

@johnniejay

Жыл бұрын

@@vickybiagini8623 100% - it seems to me like Brian (Johnson's) life is now nothing more than one long experiment.....each to their own I guess, but thats not living imo. Hes still relatively young anyway (I believe hes mid 40s), so is he really going to live like this for decades until a treatment comes along?

@vickybiagini8623

Жыл бұрын

@@johnniejay , It's just alot of work involved, and he looks his age. Every single person whose tried to reverse aging has failed. It's in our DNA to decline at a certain age. If they can change our DNA, then it might work. Aging is terrible, that I admit. I'm 49, and it's been constant in my forties. I know how bad the next couple of decades will be. At least I lived that long, some don't even get 6.

Sinclair is a fraud. Overhyping compounds that he has every intention of marketing and selling. Shameful!

This guy can’t be trusted. Just another conman making big money.