Menopause and brain health: what’s the link? | The Dr Louise Newson Podcast
In this episode Dr Louise is joined by world-renowned neuroscientist Dr Lisa Mosconi, PhD. Dr Lisa is Director of the Alzheimer’s Prevention Clinic and Women’s Brain Initiative at Weill Cornell Medicine in New York and author of bestsellers The XX Brain and Brain Food.
Dr Lisa was studying nuclear medicine and neuroscience when her grandmother and her grandmother’s two sisters all developed Alzheimer's. Dr Lisa became interested in the cause of Alzheimer’s and why women are more susceptible. Her research has shown that, rather than a disease of old age, it starts in midlife and menopause potentially plays a part.
Dr Lisa discusses her most recent paper, which found that women who took hormones in midlife to treat their menopause symptoms were less likely to develop dementia than those who hadn’t taken oestrogen.
Finally, Dr Lisa shares three things to consider about female hormones:
1. Oestrogen, and oestradiol in particular, is the master regulator of women's brains. It really is like saying that oestrogen is to your brain what fuel is for an engine. It keeps your brain running.
2. Endogenous oestrogen (produced within your body) is different from exogenous oestrogen (synthetic). The bioidentical oestradiol is probably the best one to use because it really maps on the same circuits for your own endogenous oestrogen.
3. I would love for all women to be able to make an informed decision about whether or not hormone therapy is a viable option for them. Many women who are eligible for HRT do not go on HRT out of fear and the fear comes from outdated information, mislabelling on some of the packages.
Пікірлер: 15
I’m so happy I found bio female hormones 13 years ago in peri menopause. I know my quality of life is so much better because of them. Thanks, you two for standing up for us older ladies. We deserve to be as healthy and comfortable as possible. Brava!
I am an atty and sole breadwinner for my family. The brain fog was horrible. I would have retired but for the fact i had 3 kids in college and $150k in tuition due every year. After struggling for 1.5yrs, I started HRT, because my male endocrinologist told me i would be helped, but he could not prescribe it. In a few days, I was back. And angry as hell nobody told me before. I am sure i would have developed Alzheimers in old age if i hadn't done hrt now. The gyne is threatening to take me off by 60. I guess i won't live beyond 60. This is so ridiculous.
What a precious video , on HRT since one year and a half most symptoms have resolved , still working with my professional gynecologist/endocrinologist about brain fog Dr Louise is helping lots of women she is a gifted soul Thanks for sharing blessings 🙏🏻💝💝💝💝💝💝
Just came across this video! I am reading The XX Brain by Dr Lisa and it was fantastic listening to her chatting with Dr Louise. My mum has Alzheimer’s/vascular dementia - diagnosed 18 months ago. My sister & I do not want to end up with this disease. Mum was on oral Oestrogen only back in the 90’s…it was all that was prescribed. No idea when she “came off” it? I am taking HRT as I was petrified I had dementia…started on Compound Hormones but went on regular oestrogen/mirena coil/testosterone - feel a lot better! Just up’s my dose and never going off them! Thank you ladies!
I appreciate learning about all the research about the hormones and how they can help prevent devastating illness. However, I never hear about the dosages needed to prevent them. Are the studies comparing dosages?
This is totally amazing information. I honestly could write a book based on my symptoms which i was convinced was early onset dementia starting around 2017. Here i am 7yrs on and still i am confused but im more educated thanks to both of you. Lisa...your knowledge is outstanding re the effects on the brain. Louise..i have watched your podcasts, videos, tv interviews. There is hope for me yet😊
This was me. I had to quit my job. I could barely manage and it was so frightening. Now 6 months on HRT this foggy dull felling is starting to lift.
Please provide a citation of Lisa's systematic review paper in the description, preferably with a URL, so anyone interested can have a look. Thanks
What dose of Estradiol patch is needed to decrease the risks of Alzheimer’s, osteoporosis, and cardiovascular diseases & what dose of Progesterone is needed to prevent endometrial hypertrophy?
I love your work and your contributions, Dr. Louise, May I ask that you not sit in a chair that swivels when you are so passionate and talking?! Merry Christmas and I just received your latest book which I am devouring!
Can u go from 25 mg estradiol to 50 mg (patches )with complications hope u can help many thx cheers
We just have to go by what we see and apply common sense, as the evidence in this area may sadly never come. It is neither possible nor ethical to conduct long term randomised controlled trials with HRT. Women know within days if they are on a therapeutic dose of estrogen or not. Also the ones in the HRT arm probably would get more dementia because they live several years longer, having not died following a hip fracture or cardiovascular disease in their 70s. I'll take that!
Another channel -- Create A Menopause Recovery