I appreciate this research so much. I was diagnosed with hyperlipidemia around 30 years ago. I had ridiculously high total cholesterol. (587 and 771 were 2 of the highest. No joking)I started researching and discovered that my thyroid was part of the problem. My diet was typical SAD so my HDL was in the 20’s and triglycerides over 1000. I started a low carb diet, reversed my pre diabetes and I was able to lose around 60 pounds. Lipid profile improved somewhat but I was constantly harassed by my PCP to take statins. I tried a couple times and they mad me deathly ill and didn’t really help anything. I have been eating a mostly carnivore diet for the past couple years. My hdl is in the 80’s, triglycerides less than 100 and I feel fabulous. Total cholesterol is 489, LDL sky high and I just don’t care. I’m not changing a thing. I am 70 btw. 😁

@YVM3311

6 ай бұрын

There’s a great presentation by Dr David Diamond posted 6 years ago on the myths of high cholesterol . Towards the very end he makes the point that there’s a higher risk of calcification of arteries not due to cholesterol but higher sugar levels… reversing your type 2 diabetes and bringing your insulin and glucose down is perhaps the best thing you can do for your condition . Best!

Well done gentlemen!!!

@Omnipotent_HF

Жыл бұрын

Hope you're feeling better! Looking forward to getting to chat with you on the next one!

@ericmendelman3411

Жыл бұрын

good to hear you weigh in. I pray for the world and for courageous truth tellers such as you.

The thing is ….the conditioning is so real. We have to stop referring to LDL as cholesterol. It is not cholesterol!!! It is a lipoprotein! It has a job to do. More lipoproteins are needed in the very low carb diet.

I am 69 and was treated for prostate cancer and kidney stones during Spring 2020 and had a bmi over 30. I'm 5'9' and weighed 210. My Russian-born urologist actually joked that I had fatty liver and not to be alarmed because almost all Americans have fatty liver. I was not amused, and decided to research all I could to find its cause and to see what "fatty liver" was about. I started doing keto and eventually carnivore (with occasional backslides) ; began walking 4 miles three days a week and am doing resistance training 3 days/week. I am down to 183 lbs. I got a new internist, who ironically is probably more steeped into lipo-dogma than my previous one. He just ordered lipid panels and called me at 8am this morning very concerned that my LDL was 167. I asked a few questions. My triglycerides were 43. My HDL was 86. My fasting glucose was 84. My A1c is 4.4. ApoB is 104. He wants me to start statins... CRAZY!

@Dermsurg1

Жыл бұрын

That are great cardiometabolic numbers! Best wishes

@lindabirmingham603

9 ай бұрын

I'm wondering if your kidney stone issue is gone now that you're Carnivore.

@Smokeycam1

9 ай бұрын

@lindabirmingham603 I haven't bothered to get them checked with the new doctor. I don't suffer from any pain but I should probably get them checked.

You guys are fabulous. Dave you are smart & articulate; it's exciting to feel like I'm living in a time when a major new health/medical/biology breakthrough is unfolding before our eyes. Wish I had money to gift you for research. As a LMHR I am watching this space very closely and still learning daily. Hope you write a book!

On carnivore diet 3 years and lost 30 lbs and never felt better. Now 62 yr old and fit LMHR cut points (22 BMI, triglycerides =51, HDL=88, LDL=190) had CAC over a year into diet and score =0. Thank you for helping me understand this phenotype!!

This sort of excitement and curiosity is sooooo encouraging to see among academics /physicians...

Amazing as always since only following since 2020... so much to learn! Thank you for your knowledge, discussions & research. Great roundtable - opens minds & our ways to always improve what we have been taught or thought we knew. This is a paradigm shift for most.

As an LMHR, I have found Dave's channel and of course this video, very helpful. Especially having to deal with my cardiologist.

Dave, listening again to this interview after data has come out. You are right on schedule ! :)

From Singapore- All of your research efforts are highly appreciated! I’m LMHR too - collestrol over 300, my Dr said if I don’t take statin don’t go to see him. But I asked him that since my collestrol ratio is rated optimal then why should I take statin? He had nothing to say and stopped pressing me anymore. My sister-in-law had a minor stroke 3 yrs ago and prescribed 80mg statin, after 2 yrs of taking it religiously, she now suffered from Parkinson’s disease and bone fractured, she was placed that her collestrol is now 160 down from 300+, I asked her if she’s more healthy now? My husband just had stents and Dr increased his statin to high dose, I told him not to take but he dare not after the stents. I don’t know what to say anymore!

Such a great discussion I could listen to you guys talk all day long. I'm currently a participant in the heart study so I too am anxiously waiting the results but unlike the dermatologist I don't think I can ever go vegan. That's the hard part about this, I've been keto since March of 18 and mostly carnivore since January of 20. If it turns out none of this is good for me What are the options? Eating grains? Eating more sugar? It seems so strange that reverting back to a non ancestral diet with processed foods would ever be beneficial.

@fredswolen894

8 ай бұрын

Never eat sugar lmao. If you wanna go carb, go complex carbs please

I have a higher BMI but since I have gone low carb/Mediterranean my lipids are HDL of 80, triglycerides of 71 and LDL of 161. I am 56 years old and I have this ongoing dialogue with my PCP. I can take a statin twice a week and lower LDL but I feel like crap! I am looking forward to the results of this study!

@minaprice7840

Жыл бұрын

I also got my genetics done and I am high risk for celiac and have one ApoE 4 genetic marker. I figured out going low carb made my heart burn go away.

Would be great to schedule a follow up panel discussion now that baseline is presented.

Because you mentioned it - I would love an episode with your speculations on atherosclerosis.

I love these videos!

I was always borderline high cholesterol and ldl since my early twenties but my dad had massive heart attack in his mid 50s so his cardiologist told me I should start taking statins too to prevent that. I refused since I know of all the horrible side effects not listed in package insert and ask her to get me a few months to try life style change i.e. diet and exercise. I was able to start running on weekends but life was way to hectic to change my diet and continue buying takeout for all my meals since it’s easy and I live in NYC. My cholesterol and ldl drop to an acceptable for my cardiologist. Unfortunately, I was brought up in the low fat era of the late 80s and 90s so very heavy carbs diet. By my 40s, all the signs of pre diabetes was obvious for years and then was shock that I had gained close to 30 pounds and the my blood work show I am only few points from a diabetes diagnosis! I went on low carb diet then added intermittent fasting and lost so much weight so quickly, I had to buy a scale to know if I need to modify my diet. My weight scared me so much I added back carbs so I can stop the weight lost. Another thing that was scary, my ldl went above 350s and cholesterol in the 400s! I did not want to give up since I felt better on that diet but at that time, there was no one talking about this so I added back carbs and went moderate carb so my ldl and cholesterol does not freak out my doctors. A doctor actually threw a tantrum when I refused statins and won’t give up high fat keto at that time.

do lean mass hyperresponders have low thyroid/on thyroid hormone?

I am eating mostly beef, eggs, full fat dairy an my jumbers are: Chol 19.48, LDL 16.09, HDL 2.2, Trg 0.64 mmol/l. After a liitle changes in diet - Replaced beef with fatty fish, lower amount of eggs to four a day, full fat dairy and added some vegies and berries, and there is a change in numbers - Chol 13.29, LDL 10.65, HDL 1.85, Trg 0.49 mmol/l. You can manipulate numbers with the diet very easely

@contrarian717

Жыл бұрын

Good comment. Busy trying that now. Obviously your high LDL doesn't really concern you right?

@aleksandrinasandeva7521

Жыл бұрын

I am not concern, yes. I know that it is result of my diet change. My inflamatory markers are at lowest, also my insuline an glucose. When i was eating moderta to high carbs, high protein, low fat my numbers was: Chol 3.85, HDL 1.65LDL 1.65, Trg 0.48.

@contrarian717

Жыл бұрын

@@aleksandrinasandeva7521 thanks. Interesting. I have the same LDL pattern as you. But guess I'm just too uncomfortable with high LDL given the views of the 'other' camp of experts. Now busy to also drop eggs from 5 a day to 5 a week, and do small oats after my fats (I'm addicted to macadamia) and test again.

@contrarian717

Жыл бұрын

Edit: thanks for your great tip, helped me a lot. Dropped my eggs, less fasting, added carbs - LDL dropped 60% (and HDL, trig's improved).

What will be interesting is to see if LMHR are at any risk of insufficient insulin response. If protein is enough or needs to be delivered in less frequent but higher doses or if carbs are useful. If so at what cost from the Randle cycle ?

Hey, thats me too! My doctor is freaking out over my high LDL levels though. Had the CAC test and it was zero. Dr. wants me on statins asap

Super excited when I saw this in my YT feed. I find this all fascinating and I’m not even a LMHR. Dr. Victor, I have a hypothesis related to skin cancer and cholesterol. The SAD , poor lifestyle , and possibly the use of statins, over time relocates our sebum/cholesterol from our skin to sites of inflammation such as heart disease. This in turn makes our skin vulnerable to cancer causing sun damage. I wonder if skin cancer is due more to the vulnerable state of our skin which has lost so much sebum. I also wonder if this is a contributor to low vitamin D in so many. This is why I use pure lanolin mixed with a fat and a tiny bit of fragrance on my skin for a few reasons. I use it regularly on my face and sometimes on the rest of my body as a protector from moisture loss and from sun damage. I do this mostly because it is most like our sebum. I have found it even works for bug bites and a severe ugly itchy breakout my husband had one time. This summer I have used it as my sunscreen. I have yet to burn and I am blonde and fair skinned living at about 35° latitude. Thank you all!!!

@janepowell7556

Жыл бұрын

What fat. Thanks for sharing.

@MonicaLovesDogs

Жыл бұрын

I would love to know your recipe😊

Very exciting!

Hi guys, very interesting conversation. To add to your coronary scan study and your hope to not see a progression of plaque after 2 years, i would like to share my own results. Before i started keto, i have done several artery scans, not coronary though, but only at the carotid artery. After 1 year doing keto and with a much higher LDL-C level (136 before keto to 240 after keto) i went back to scan my carotid in fear the little plaque i had would have gone much larger. It was the oposite, in fact on one side it almost disapeared. On the other it went down by half. I am will do a calcium coronary score test in a month, to have more information..

@jlieut

Жыл бұрын

Following up on my last comment, i have now done a coronary scan, calcium score, and sadly the result is bad: 530. Although its bad, it does not tell me if any info related to the keto diet i have been folloing for 18 months now, as i havent done the test before i started Keto. So i cant compare. I am now doing a visit at my local hospital in 3 days, to do a full coronary scan with iodine injection to check if i have any blocage in my coronaries... I thought i was invincible, i feel great, i eat healthy, i excercise a lot, i am 8% body fat, but my arteries dont seem to reflect how i feel. So please, even when you think everything is fine, dont hesitate to test yourself and make sure you are not at risk. CAC scan is really helpfull

@BigPoppaSTL

Жыл бұрын

I hope that everything goes well with your scan. Very interested in your results.

@jlieut

Жыл бұрын

@@BigPoppaSTL Hi, so i've done the coronary scan with iodine injection, much more invasive this one compared to the calcium score scan. But you have a much clearer picture of whats going on in your heart. All my arteries were fine, in very good health, with NO plaque, except for that little calcified section, but with NO reduction of the blood flow. The conclusion of the cardiac surgeon was that this is probably and old inflamation stabalized a while back. If we take as a reference the plaque in my carotid arteries that decreased over the last 18 months went i went Keto, then we can may be imagine that the plaque in the coronary artery has been there for more than 10 years, and also decreased in size. I can only assume this, and we will never know for sure as i didnt do this test before i went Keto. But one thing is for sure, the calcium score result of 530, which means very high risk of CardioVascular Desease, does not reflect reality. I was sent home releaved and the surgeon did not even put me on any medication.. to be continued

@BigPoppaSTL

Жыл бұрын

@@jlieut That’s some great news. It’s crazy that your calcium score was so high and then the coronary scan with iodine injection came back good. I’m sure it gives others hope that just because one test shows something negative that it might not be totally correct in predicting their weather they are healthy or not. Thanks for sharing your experience!

Thank you!

I went HEAVY sat fat for 6 months(beef/eggs/dairy). Extremely low/zero carb and high fat. My LDL went up to 660. TR:89 & HDL:96. I'm relatively lean and exercise several times a week.

@bloodforfeit4756

Жыл бұрын

+ bacon/sausage/pepperoni etc

Hello! Love the content!! I just had a lipid NMR test done, LDL 183, HDL111, Trigs 62, TCHO 303.. Female 52 yr old 5' 2" 153 lbs and I lift weights, is this what you call borderline LMHR? I still have 30%BF but carry 59lbs of muscle, been Low carb, keto/carnivore for years (yo yo style :( ) Thank you for the research!

I think we’ve been asking the wrong question with cholesterol and LDL-C levels. The question should be, does the mechanism causing the elevations matter?

And why are we running long distances? I hate to spoil the party but don't come crying to me when you're in your sixties and your knees are arthritic. Also, Dr. Al Sears believes long distance running won't do any favors for your heart. He argues that doing short intervals (bursts) alternating with slow breaks is safer, more beneficial, and takes a lot less time.

@robinbeers6689

Жыл бұрын

Yes, Mark Sisson (Mark's Daily Apple), a former ultra marathon runner, now has the same opinion. He advocates either short fast bursts such as sprints or else low-and-slow training such as hiking or long walks.

So we still don’t know..

@jillengland3277

Жыл бұрын

Yes we know the current standard of care is incorrect for some illnesses.

The discussion about training/running and keto is really cool. It is super interesting to hear other perspectives on this. My earliest heavy workouts way back in high school were all in a fasted state. Later, having food during a performance event was a learning experience. I would suggest that the ability to efficiently use fat as primary fuel is a very long term adaptation; more like decades than years of adaptation. Yeah, the first 5 minutes of a run or bike can be brutal...wrestling with the big dog. And then everything is ok

This hypothesis really makes sense. It would explain why blood lipids, triglycerides, and blood sugar are all very high in cases of Diabetic Ketoacidosis.

On- importance of naming, metabolic health and positive feedback loops: Diabetic keto acidosis is a key example of all three. It’s actually insulin insufficiency…. Ketones have as much to do with causing it as ashes have to do with the destruction of a house fire. But to this day- MOST endos and diabetics don’t actually understand that. Names do matter. I agree that a positive feedback loop would be seen relatively easily- like DKA. Spinning out of control is pretty easy to observe. One thought- it is possible that the default state has the possibility of instability- for the benefit of reactivity to environmental conditions. However, a “switch” is flipped (like new gene expression) to make the system less responsive and more tolerant- with the trade off that things that would have been tolerated without damage will subsequently accrue tolerable short short term damage to prevent immediate catastrophic instability.

On the athletic performance question. I run half marathons. I train on keto (burning fat) and then on race day, I eat carbs. The difference in performance between training and race day is significant. Performance is much better on race day.

@Omnipotent_HF

Жыл бұрын

Thanks! As stated in the video, I'm training for my first marathon so any tips would be greatly appreciated 🙏

@Dermsurg1

Жыл бұрын

Would be interesting to know how your serum blood glucose responds to a sudden reintroduction of carbs on race day. The dogma is that long term carb restriction leads to down regulation of insulin sensitive - glucose receptors on muscle cells: physiologic insulin resistance. But if it works, fantastic! Personally, I find I can't cycle in an out with good effect.

@applerunner1184

Жыл бұрын

@@Omnipotent_HF it works really well for me. I did wish that I had practiced this before my first race as I had no idea what my target pace should be and as a result left some time on the table - it is hard to overcome the fear of carbs when training :-). I actually got the benefit during my second half marathon as I knew exactly what my pace should be. Managed to shave 3 mins off my time…

@Omnipotent_HF

Жыл бұрын

@@Dermsurg1 Yes! I was thinking that it wouldn't be as efficient as I imagine if one is keto-adapted, then the opposite is potentially true that I am not glucose adapted (while obviously, glucose does not go to 0 on a KD, I would still assume that I would use it less efficiently).

@Omnipotent_HF

Жыл бұрын

@@applerunner1184 Amazing! I'll need to do a trial run with this strategy before race day! Running my first marathon on October 1 (haven't done a half yet, haha.... Jumping right in!

I would really love to hear some f the questions discussed again a year later …. What do you guys think of the one guy in Australia that did 5 marathons in 5 days while fasted ?

Please bring Don Layman. He is a protein researcher; however, still lots of relevant insights regarding metabolism and energy.

Has it been demonstrated that the high ldl in lmhr is detrimental? Beyond just association...

Super duper discussion. LDL is a part of the immune system. So removing LDL is like adding visceral fat where the visceral fat sucks up t-cells. The person will not die overnight but living with a weak immune system simply increases the risk of metabolic degradation from pathogens and other damage-inducing chemicals

Zach Bitter maybe able to answer about running and Ketosis

Interesting that the chap said his LDL on keto and statins was 120 and the group seemed to think that was low. Mine on keto and 40mg atorvastatin was 25...

How Dave skin looks so amazing and glowing 🤔

are you going to differentiate between soft plaque and hard plaque on a CTA?

I am a late onset type One diabetic, my. LDLs were perfect before I started my low carb journey, but my sugar control was poor. Now on the low carb keto lifestyle for the last 15 years or so, my sugar control is great but I have the typical hyper responder triad. I am a workout nut, constantly doing something physical, cycling, kettlebells , throughout the day etc. My LDL at 3 months blood tests is constantly high but keeps changing from 3 to 5 moles regardless of what I eat. I am unsure if my cardiac risk is high , but I feel amazing physically .

@contrarian717

Жыл бұрын

Same here. I find LDL to vary quite a lot. Coffee even influence it, fasting. Recently I exercised 90min before blood test. My T3 and testosterone plummeted. But LDL was at a possible perfect 2.2

@tomunderwood4283

Жыл бұрын

Is it possible that high LDL May be beneficial if one is metabolically healthy?

@contrarian717

Жыл бұрын

@@tomunderwood4283 from my own experience and testing and from what I read from new research and from many testimonials I'd say yes! However LDL remains a huge debate, as you will know.

@Malcolm-Achtman

Жыл бұрын

@@tomunderwood4283 Probably.

@fathmatharifa3481

Жыл бұрын

That is great for a T1DM 1k where many people simply give up due to improper support/guidance in health care world wide. Wow! May be analyse the LDL by particle size. Small dense is wicked and do coronary calcium and anything else that helps to know your cardiac risk.

Are there any medical researchers with specialised knowledge of K2 (menaquinone family of molecules) that you could bring on?

what is benefit of crestor? anti-inflammatory?

What about the lipitor crossing the blood brain barrier? I was on atorvastatin and I had headache in my right eye / cheek bone... sure enough, found out that was a side effect, quit the statin (only on it a year) and the headache/eye ache/cheek bone ache went away? I had NO idea that it may play into a dementia and Alzheimer's???? UGH!!

do you guys know relationship of LDL particles and immunity

I’m curious if Mediterranean Diet is reducing LDL but also stripping LDL benefits through plant cholesterol/sterols uw

YES!!! PCOS is a horrible name and males can have a version of it also. Now we all know it is the result of IR and hormone imbalances. I wish I knew I had IR decades ago especially when I had my children. I was able to have children at 40 & 43, but there were complications including placenta abruption with our second, which now I believe was due to fibroids caused by IR. I never had many of the outward signs, nor did I have irregular menstrual cycles until I began to approach menopause. Thankfully I had an ablation done instead of a hysterectomy and/or pharmaceutical intervention.

Hi Dave, could you please also share your ApoB/A ratio? Also, why LMHR look at this ratio as a red flag? If the LDL goes up, it's obvious that the ApoB will also go up..

@Malcolm-Achtman

Жыл бұрын

ApoB and/or the ApoB/A1 ratio are pretty useless because ApoB tells you nothing about the nature of the LDL particles (e.g. the number of LDL particles that are small versus large). It's possible for a person to see their LDL and ApoB increase on a low-carb, animal-based diet. But at the same time, their number of small LDL particles could decrease (which is good).

@lgg898

Жыл бұрын

@@Malcolm-Achtman it's about number not size, ApoB is best marker.

@Malcolm-Achtman

Жыл бұрын

@@lgg898 Some experts would agree with you, but others would disagree. NOKAFS (No One Knows Anything For Sure).

You can't do a double-blind placebo-controlled study with one group taking a statin versus one group taking a placebo. Why? Because the people in the statin group are likely going to feel like crap (e.g. muscular aches, lower energy, brain fog, etc). So, they'll know whether they were given the statin or not.

I have been 100% carnivore since January 2022. I recently had my lipid panel done and the numbers have me scared. My LDL was 1,087, Triglycerides 113, and HDL 57. I am 32 and 125lbs for reference. No diabetes and active. Any thoughts?

@alanlierz3745

Жыл бұрын

Don’t worry Brittany. LDL is good for you. If you eat carnivore truly your body will function like God intended it. There is zero evidence that high LDL causes heart disease. You can check your Coronary Artery Calcium Score for a better indicator of atherosclerosis. Whatever you do, please don’t take a statin or go Vegan. If you don’t exercise then start. Keep all other metabolic markers in line . Enjoy your steaks.

@brucehall9399

Жыл бұрын

Holy shit! My doctors said I have the highest LDL they’ve ever seen and I am only hovering around 500. These assholes like to call me “the winner”. You, Brittany, are the winner.

@fredswolen894

8 ай бұрын

I would advise you to test your calcium score and arteries. That’s the only true and important reading one needs to see if they’re doing things right.

I give you this to think about. Both my father and I are lean mass, physically fit and muscular. We both take care of what we eat and our overall health. When we ate animal protein and fat, our LDL was dangerously high. Upon eating mainly plant-based, the LDL dropped. Now lowering our carb intake, the LDL shoots up dramatically. Other family members of ours live normally, not exercising intensively and not being careful with what they eat, still snacking and eating sugary stuff. Some are not fasting at all. And they are fine. How about that? -__"

@kathya1956

11 ай бұрын

Are they fine?

Fave how do I get on your hyper responder group?

AT 91 minutes in, I would love to have a conversation with the running Dr's inability to run 5ks and distance to pre keto performance levels. I suspect he could train and adapt and improve his performance. I've been carnivore for nearly 4 yrs and have improved (incrementally while aging) since the heavy gel days. My base line performance prior to keto was still pretty good fwiw.

@Dermsurg1

Жыл бұрын

Id love to hear your suggestions. I have been largely ketogenic (by finger prick) for 3 years and my mile pace has sunk prodigiously, despite being 12 pounds lighter. Do you cycle carbs?

@amfmharle

Жыл бұрын

@@Dermsurg1 a quick reply: I don't cycle carbs. I add small amounts of onion, tomatoes or jalapeños for flavor to meat based meals. I measure ketones daily to reveal very low ketones despite eating fewer than 30g of carbs a day. My blood sugar is fairly stable, and responsive to exercise, stress, and carb intake exposure. Concerning training, I've had solid results following a 80% ez and 20% hard plan. Being 47, I value slow adaption to speed every season. 30sec on 30 sec off repeats do wonders, building from 10 to 35 over a few weeks. 2 min hard repeats up a 4% grade, jog down. 4min efforts on 8 to 10%, jog down. Also Ladder work: 30, 60, 90sec, 2min, 3min, 4min, 3min, 2min etc. W/ rest equalling the hard dose. Build power and mental resilience. All threshold and above work is done 6 to 9 hrs after a morning meal. My ez days are done before eating or 3 to 12 hrs after eating. The longer the better though. Everything requires an adaption period. Often breakthroughs happen when you change a routine. Rest is required. It's best to not run everyday. Don't do split squats if you have a hard session the next day. Do deadlifts. I think cycling carbs can become a mental crutch and can hinder confidence in performance. They can help, but they're not required. You will break through. I'm not the fastest runner as I don't quite have the genetics, but I podium frequently, win sometimes, and am not afraid to start slow and finish strong.

@amfmharle

Жыл бұрын

I went from 13% to 5% body fat within a few months and have stayed there for 3 plus yrs.

I have a low bmi, always around 18.5+-0.5 for forty years since I hit puberty. I tried keto for 4 months just for curiosity. Amazingly, I haven't burped and farted once for these 4 months and don't need body lotions after shower. Before keto, my ldl is 150+. Currently I just did a blood panel with Thorne and my ldl is 200+. Tri 96. Hdl 80. Am I a LMHR?

@kathya1956

11 ай бұрын

Did you do your blood test fasted for 12 hours?

It looks like I qualify for the LMHR study on all requirements, but I am on the east coast and it’s a long trip to take.

@annemurphy2046

Жыл бұрын

It's worth it for the valuable health assessments you get in this study!

@nicknorwitzPhD

Жыл бұрын

They pay for the flight and hotel. If you've been LHMR for at least 2 years, you may be eligible.

8m a lay person who doesn’t understand all the scientific terms but still get the overall drift. It this very important that we ordinary people have access to this information,otherwise I would have been cholesterol lowering meds long ago. I’m 74 and keto dropped my triglycerides from200 to123 in a matter of weeks I need to do a better job on keto and I’m working on it. I consider myself very low carb as opposed to keto I don’t feel well on keto. I believe there are some people who feel much better on glucose rather than keystones NOT BECAUSE THEY ARE ADDICTED TO GLUCOSE, BUT BECAUSE THEIR BODIES FUNCTION BETTER ON GLUCOSE. I think that may also explain why some become carb addicts in the first place. I BELIEVE ITIS A MATTER OF “the chicken and the egg”. Did people get addicted to carbs because their bodies need the carbs and carbs rewarded them with a sense of well-being when they consumed them and when they filled that need? That’s the million dollar question 🥴

Why do more people with low LDL have more heart attacks than those with high LDL?

@fredswolen894

8 ай бұрын

Doesn’t apply to LMHR. You’re generalizing a very gross rule of thumb.

Is it possible that crazy high cholesterol/LDL is the result of the liver not functioning properly? This is one of my concerns.

@kathya1956

11 ай бұрын

Easy to find out with blood tests

12:20 into the video and looks very good, but time to sleep, to be continue, thanks everyone

Does gut bacteria have an impact?

I wish we could rename IR!!! Instead call it “chronic hyperinsulinemia” “CHI”. 🙃 I believe it would be easier for patients to understand it is due to their diet and lifestyle, thus they are in control, of improving their health.

This is interesting my LDL went up from about 130 to 235. I went keto because my A1C was 5.9 a couple of years ago Turns out my exercise spikes my blood sugar. My fasted insulin the past couple of year is 2.3 or less so not insulin resistance. I am a IFBB Figure competitor. I wear a CGM. My average blood sugar is less than 100. So I don’t intend to add carbs back with the information I have now. Also I feel amazing.

I’d rather die of a massive HA at 65 than get dementia at 70 and not know who or where Iam but be “alive” to be milked like an insurance cash cow.

This non-scientist layman enjoyed being a fly on the wall for this discussion.

👍 👍 🙏

I am wondering what the average A1C is for LMHR's - is this data that is tracked and available somewhere? Is it higher for these people than most keto/carnivores ?

@Malcolm-Achtman

Жыл бұрын

Over time as I've transitioned to a more animal-based (low carb) diet my cholesterol values have certainly gone up but my HbA1c has remained fairly steady. I prefer tracking my fasting insulin. It's holding reasonably close to 4 uIU/mL and I'm happy with that.

@entropy0917

Жыл бұрын

@@Malcolm-Achtman Are you a LMHR?

@Malcolm-Achtman

Жыл бұрын

@@entropy0917 I would say I am a LMHR or close to it. I think I would fit the characteristics used by Dave Feldman, both in terms of what my lipid values were most of my life prior to changing my diet and how much they changed after I moved into a more animal-based diet. I could give you actual numbers if you are interested.

@entropy0917

Жыл бұрын

@@Malcolm-Achtman Thanks - No need for numbers!

@raquel5401

Жыл бұрын

my A1C is 3.8 and i am LMHR- ldl 304, hdl 87, triglycerides 43, bmi 21, bodyfat- 18.9%

TOXIC MO HERE...I THINK I HAVE AN INSITE ON HYPER RESPONDERS

I agree a lean mass hyper-responder is metabolic, not genetic. My identical twin brother and I always had similar lipids back in day (e.g. low HDL (35 mg/dL), highish trigs, average LDL - say 130 mg/dL). I've moved toward a more animal-based (low carb) diet and my cholesterol and LDL shot up, my trigs went down, and my HDL increased. My brother meanwhile was still eating a higher carb diet and his HDL still hovers in the 35 - 40 mg/dL range, whereas my HDL has risen to as high as 70 mg/dL.

@pong4life

Жыл бұрын

Nice to have a twin for comparison. I am thankful to have made the transition to low carb and then found so many LMHR's for comparison.

@robinbeers6689

Жыл бұрын

You should reach out to Dave. I'm sure he would like to study you and your brother.

@Malcolm-Achtman

Жыл бұрын

@@robinbeers6689 Nice suggestion but I'm afraid that would be a distraction. I think Dave has carved out an interesting study approach on which to maintain his focus.

@robinbeers6689

Жыл бұрын

@@Malcolm-Achtman Your info might not be relevant for the study he's in the middle of right now but it could be useful eventually. Wouldn't hurt to ask.

A fantastic discussion with abysmally low views. This is The Beatles Get Back for health.

@nicknorwitzPhD

Жыл бұрын

What an endorsement!

This is me.

At 13:01 -With respect-if you are concerned that your cardiologist might fire you as a patient I suggest YOU fire HIM as your doctor and find another cardiologist who has “gotten the memo” so to speak.

How about the possibility that the cholesterol in atherosclerosis comes from the red blood cell "The clot thickens" by Dr Malcom Kendrick.

why do all say diet doesnt affect cholesterol?

Is anybody concerned about the inherent selection bias of picking people who have been on this diet for a very long time? If the diet had accelerated their atherosclerosis then they would have suffered a CVD event already before they even applied for the study. So perhaps the study should not include people who have been on the diet for e.g. more than 5 years.

At 1:31:30 about running on keto and Dave’s comment, this is exactly what Tim Nokes has observed. The brain is wired to stop BUT an elite ultra runner on keto can over pwr this and excel. Interesting. On the new name topic Pro-Lean hyper responder takes anyone who leans toward becoming lean even if they are in that metabolically active start of their journey but do not show weight loss yet. No less a crappy name than non alchoholic fatty liver disease 🤪

Dave, I respect you so much, but I may not respect your microphone. Please upgrade you microphone.

I'm shocked how intimidated this DR is from his "cardiologist..." I'm a long distance runner, and there is no question, I run better on carnivore. I couldn't image running fast, on a long distance run, on a bloated, swelled up, belly full of carbs. This goes for myself, who has a decent testosteterone level...

@applerunner1184

Жыл бұрын

I train for half marathons on keto and strategically add a few carbs on race day. Performance is so much better. So much so that I find it hard to predict my race pace…

Need to fire your cardiologist and get a new one!

i want to know if anyone of these folks pushed covid therapeutic remdesevir and covid vaccine

My total cholesterol on paleo was 128. My LDL on keto with vegetables was 152 (TG 58; HDL 80) My LDL on carnivore was 277 (TG 55; HDL 110; VLDL 5). Now more like ketovore with occasional berries and apples around workouts. Not sure of my numbers now, but I’m sure my doctor would be happier with it at this point.

The dermatologist guy is 57 ! .He looks 47 .

2 hours, no time stamps aaarrgh...

can a diabetic be a hyper responder? because that's me

Dave is being diplomatic. Statin use for high LDL does not reduce all cause mortality.

Cardio (long running) is NOT natural behavior in humans. So this should not be measurement criteria. I am LMHR and I would propose one change... It is ratio of hdl to trig that should be considered. When my hdl rises it reduces ldl automatically but hdl to trig ratio remains constant at 0.75 or less. (0.72 in my case)

These conversation are frustrating to me. Harvard continues disappoint cause they live in a perpetual echo chamber. Talking about LDL is in itself refusing to recognize that LDL poorly correlates with CAD. If you were actually giving me something useful like the LDL-P informing me what type of LDL you have. Type A or type B. Michael is wrong . And if you increase your carbohydrate you will kick yourself out of ketosis. Your tryglycerides will increase and your HDL will drop. And if your not in ketosis and overdoing the sugar will change the type of LDL to type B. If one continues to see cholesterol as the arson that burns down the house, rather than as the fireman coming to put out the fire our knowledge on the true ethology of CAD will never progress. Statins have zero mortality benefit. I believe they do incredible harm. They block production of Vitamin D2 resulting in calcification of arteries. I don’t buy into the concept that hyper responders are an issue at all. And I further could careless that LDL is high unless your telling me it’s type B. And let’s note statins have zero affect on changing type B to Type A LDL. Additionally buying into So called markers of possible heart disease like Lpa is again mistaken thinking. Lpa is necessary part of our repair system that has been maligned by those believing in the cholesterol hypothesis. When are we going to accept it is wrong and stop? Dr. Ginge. Start from the Cholesterol paradox. All cause mortality is higher in those with low cholesterol. Dr. Ginge

When your on a low carb diet cholesterol raises because progesterone, androgen and estrogen are lowered so to make up for the loss , cholesterol raises because cholesterol controls these hormones

@veniqe

9 ай бұрын

Not necessarily, no. I'm on a low-carb diet and my LDL cholesterol is super low.

@brucecampo6543

9 ай бұрын

There are exceptions to every rule 😊

I'm with Dave and this low-carb angle but after watching dozens of hrs on subject like this, for the everyday person, it just does not matter. Meaning the numbers you guys are playing with as good or bad numbers... If you are a fat F, that is YOUR problem and losing body fat should help your health ... For the rest of us, cut out the sugars and man-made ~food, do some exercise of your choice, and your body will do the rest.