Great video explaining using lithium. Doctor extremely knowledgeable.

Great video. It looks like Lithium is the best treatment for bipolar, yet it is being less and less prescribed in favor of antipsychotics. I think doctors don't want to deal with the monitoring of lithium levels.

@johna5484

Жыл бұрын

More money in the new drugs. No patent on old time lithium.

@sethpawlik

Жыл бұрын

Big PhRma wants big profits. Lithium is cheap.

@landofthelostful

11 ай бұрын

@@johna5484 That isn't the reason it isn't being prescribed. Today, prescribers do NOT make money prescribing certain medications. It is even now illegal to receive any financial gifts or otherwise from pharmaceutical companies (thankfully). Instead, as a prescribing practitioner, the reason lithium is not prescribed as much is for a couple of reasons. One, pharmaceutical companies are advertising and pushing the newer medications like antipsychotics for bipolar disorders. Even prescribers fall bait to the advertising, but the reason is because of the second reason, SIDE EFFECTS. The side effects are absolutely significant and even more so than almost all the antipsychotics (second generation antipsychotics). Furthermore, the therapeutic window (0.8-1.2) is so narrow that even going beyond it just a little can be dangerous if not lethal. That means even sweating too much or not drinking enough water or taking something over-the-counter can be deleterious to the patient, who should also never drink alcohol. On that note, I don't know why anyone would consume alcohol to begin with. It is a central nervous system depressant (even one drink). It literally makes you depressed. Also, just assume you are going to end up with hypothyroidism, which is going to leave you exhausted and further depressed and hopeless. Additionally, because lithium has a delayed onset of action to reach its full efficacy, it often isn't the first choice in acute mania, but rather maybe used as an adjunct. I am not saying I agree or disagree with this approach. I am just stating why this is happening. Also, you can't use it for mixed mania and rapid cycling. So there is another reason. These are the reasons why it isn't being used as much. It isn't because of money regarding the prescribers. It is certainly the intention of the pharmaceutical companies to make ridiculous amounts of money off medications, but to blame one side or another is just narrow minded. Society would rather be put on medications than make significant changes in their life. I know this first-hand as a practitioner no matter the patient and no matter what any non-expert in caring for patients say. Some patients are willing to make some changes, but only to the extent that it is easy. Beyond that, forget it. Now, I am not blaming patients in the least. I am not blaming anybody. I am pointing out that people want quick fixes no matter the diagnosis. They don't really want to change and to really heal is to change. Otherwise, you take a medication and then you take another medication for the side effects of the first medication and on and on. Then everybody blames medicine, the healthcare workers, and the pharmaceutical companies and on and on. The pharmaceutical companies take advantage of these things. It is all just a vicious cycle. You are speaking of things that has no basis of truth and that in itself is dangerous and extremely narrow minded.

@OfficialRogue

5 ай бұрын

​@@landofthelostful as someone with bipolar disorder, I WHOLLY disagree with the point that lithium side effects are more significant than any SGA (second generation antipsychotic) let alone "almost all". Lithium is generally relatively safe if properly monitored and kept within the therapeutic range (or lower since low-dose lithium also has its uses and works for some patients), which it should always be. Antipsychotics on the other hand almost always come with unavoidable, heavy side effects... The most obvious one being SIGNIFICANT weight gain (which doesn't or rarely happens on lithium, or at least not to that level) and metabolic syndrome, sedation, difficulty waking up in the morning and day-time drowsiness, anticholinergic side-effects (like dry mouth, plugged nose, etc), sleep changes (nightmares, sleep apnea if weight gain, etc), and generally not great for the liver even in healthy people... compared to something like quetiapine (Seroquel), taking lithium feels like nothing, as long as you avoid dehydration and other things that you should be avoiding anyway (like alcohol as you mentioned). To me antipsychotics are extremely potent drugs that should, like benzodiazepines, preferably be used only for short-term acute treatment (e.g. manic episode or depressive episode adjunct therapy). Although many guidelines may include them for maintenance, there is still less evidence that they should be maintained past the acute phase, and this is often criticized given the bad risk-benefit ratio of doing that, and the tolerance created over time that only makes it harder to get off them if needed (e.g. if a breakthrough episode happens and treatment needs to be switched), and exposes patients to withdrawal or rebound syndrome that can kick in even months later and look like another episode when it's not. Their effect on the metabolism alone cannot be ignored and is a trade-off/risk that patients are rarely made aware of about with enough gravity beforehand, especially when it comes to maintenance. A lot of them become more depressed after such massive weight gain. You might assume that the trade-off is worth it if it means gaining motivation back to exercise etc... but that's often too optimistic and leaves people worse off not only health-wise but about their self image. Even when the weight gain doesn't happen the sedation, fatigue and other side-effects, and just how they make you feel in general is just not ideal at all. They are a useful tool in acute phases, but I can't recommend them at all as a first-line maintenance option. I would more readily recommend something like lithium or lamotrigine before settling on antipsychotics. When you start these outside of acute episodes, they are more likely to be good at prevention and act as passive maintenance treatments that you barely feel most of the time, with the right monitoring and hydration/nutrition (which you should be doing anyway).

Guy I knew back in the ‘70s took too much acid, had to go to hospital then to the crazy house. Has been on lithium and an array of other drugs since. Was a good guy, nobody even recognized him after that event.

@graemegeorgeharrison2468

6 ай бұрын

That’s sad, I’m also very damaged from too many psychedelics

@gtron7692

5 ай бұрын

Makes me wonder what impact exogenous drugs play in current occurrence of schizophrenic-type of mental symptoms. Seems like modern street drugs, like meth, can really make things worse.

Lithium is a lifesaver , don’t like antipsychotics though

@burprobrox9134

3 жыл бұрын

Agreed

Great video! I can only take the 450 CR tablets. My body doesnt agree with the other forms. Works great for me. Though tons of side effects.

Thanks Doctor, I take lithium and this discussion was very helpful.

Thank you so very much for this video..I better understand things now..I've been taking lithium carbonate for 7 years now...My regular dose is 450mg a day..I take 300 in the morning and then 150 at night. Sometimes though I have to take 600 mg a day..

1. Dose is important. 2. Dose is important according to behavioural evidence, and blood tests. 3. Dose volatility depends on many factors, as described by wellnowdoctor. 4. Loading and discontinuing should be done gradually. 5. Physical condition of patient should be taken into consideration. 6. Interaction with sodium, ACE inhibitors, and other drugs or OTC meds should be checked for their effect. 7. Blood tests and personal reports of the patient should be more frequent than once a year. 8. Age and weight may be considered. 9. Lithium is the gold standard for a debilitating and dangerous biological illness which has psychological and physical effects. It is worth monitoring with care, just like other debilitating diseases deserve and get care and monitoring. 10. Monotherapy should be preferred to combining psychoactive drugs, even though it may take some more time. If one drug is a challenge due to its complexity, two or three can rise exponentially in interactions. Bottom line, reading some material on the safe use of lithium, and considering personal reports can eliminate many adverse effects and the risk of toxicity. This can also make the procedure of lithium treatment a much easier job for practitioners.

@UpFromUnder6

9 ай бұрын

Thank you kind person!

Thank you for such an informative video, I currently take Quetiapine for pyscosis from Bipolar 1, I am going on to Lithium in the upcoming months I am hoping it is the right medication for me, though the side effects worry me but they can't be worse than what I get from Quetiapine.

@truehope287

Жыл бұрын

How are you doing on Lithium? It was a life saver for my son

thanks

I'm on lithium, 900 mg a day. I have BPD & Bi-Polar Disorder. It's good but I don't like having to have to take blood levels every month or so.

Love this Doctor I'm on Lithium Depakote and Klonopin for Manic Depression finally I'm getting better

@nicolevonw8101

3 жыл бұрын

Lithium Orotate may help! ❤️

@XenoTravis

3 жыл бұрын

Long term use of klonopin is insanely dangerous. I am almost on a year of a taper and the side effects are near being tortured slowly. It is often seen as malpractice. Hopefully you do well or change to a longer acting benzodiazepine.

@taghreedrulia5168

3 жыл бұрын

Jahid Afridi That who put you on Klonopin is a criminal! You may probably know what I’m talking about by now! If you take Klonopin one time a week you’ll develop tolerance because this crap has an incredibly long half life! Also,I don’t understand why were you put on both lithium and depakote together!? This is a prescription of death(liver+kidney)damage and you’re happy you’re getting better!!

I'm schizoaffective (depressive type), I've been on many antipsychotics but they work bad. Today I got lithium to try to boost my antipsychotic. I'm half very angsty about the new drug and half thinking about the nirvana song.

This guy must be a genius. Recalling all facts and knowing how all drugs function in the brain and body- crazy! LOL! But helpful to a lot of people!

@clintparsons3989

3 жыл бұрын

Teleprompters help lol

@jessicarose3904

3 жыл бұрын

I could recall half of this stuff from memory just from 20+ years of treatment of bipolar disorder. Find yourself a doctor who actually explains what they are doing and why and doesn’t just throw pills at you

@nicolevonw8101

3 жыл бұрын

Yes Jessica! I don’t take anything, but yess! People need well educated docs!!

@nicolevonw8101

3 жыл бұрын

@clint lol I think he really does know it all

Hello, I’m a new subscriber to you channel. You definitely know what you’re talking about, sir. I have a request: Could you please do a video on Thorazine (chlorpromazine). I have bipolar type 1 I take Lithium CR-450 mgs. bid. Though now they’re adding Thorazine 100 mgs four times a day. (Q.I.D) Nervous about Thorazine.

I ❤ ur smile!!!!!!!!!!!

Recommendation of two books on lithium and manic-depression: "Manic Depressive Illness" Frederick K. Goodman Kay Refield Jamison Oxford U. Press 1990 "Lithium in Neuropsychiatry" The Comprehensive Guide Michael Bauer Paul Grof Bruno Muller-Oerilnghausen INFORMA 2006

Well, this guy knows his stuff! But I can't tell whether he's reading off a teleprompter or not. If not, he's hired! Lol.

@damonskaff8710

3 ай бұрын

Yes but he died btw...

does a smart phone help

What is side effects of high level of lithium in blood ?

Is Lithium and Lamictal a safe combination? I read a study saying they’re not supposed to be mixed.

@jahidafridi6318

4 жыл бұрын

No it's not a good combination I took lamictal with it was a bad combo

@burprobrox9134

3 жыл бұрын

Well that’s what I take and it’s improved my life considerably. Everyone is different and responds differently, that’s why there are different medications for the same condition. I tried many combinations before I arrived at lamictal + lithium.

@tamesmorful

Жыл бұрын

It’s a good combination!!! Lamictal helps depression polo if the lithium isn’t enough

Lithiumcitrate is perfect.

Hi, can you please talk about SAMe?

900 LCR here. I love love love looooooove my lithium 😂. my suicidal tendencies went away.

I have been taking Lithium for 38 years. Prior to that I was being treated with medication for Schyzophrenia. I am now 77. I have many unpleasant side effects

@cheryld4437

Жыл бұрын

I just started taking lithium 4 days ago and my menstrual cycle is Extremely heavy. I am on day 10 with no end in sight!

@stevegovea1

10 ай бұрын

I'm in my 3rd year... I plan to get off Lithium between my 5th and 8th year.

@stevegovea1

10 ай бұрын

​@@cheryld4437 I hope all is well. Thank God for this med, I'm glad I don't think I'm Jesus, lol.

whats the difference between lithium carbonate and orotate

@lilm1234

4 жыл бұрын

Andrew James well, lithium orotate is bought over the counter and far less potent then carbonate. Orotate isn’t recommended by most psychiatrists because levels won’t be monitored. Even though orotate is much lower compared to prescription lithium carbonate though it should still be monitored.

@jahidafridi6318

4 жыл бұрын

Lithium Oritate is natural supplement and it's not monitored

@lenayamamoto

Жыл бұрын

Orotate is lithium bond with oratic acid which carries lithium through blood brain barrier. Lithium is mostly needed in the brain so taking low dose of lithium orotate is better choice than poisoning body with super high doses of lithium carbonate to get just a lil bit into the brain. You don't risk ruining your kidneys with lithium orotate. You only need like 5 mg a day which isn't dangerous for body yet effective for brain.

Nothing happens to the thyroid with Citrate.

I took 300 mg of Lithium once and I became so hostile and aggressive that I was punching walls and behaving erratically. Not the drug for me.

@lilm1234

4 жыл бұрын

Obsessive Delusion low dose lithium did the same. Immediate release, right? The capsules? CR helped dramatically though. Currently on 900 mgs..

@jahidafridi6318

4 жыл бұрын

Not for everyone sorry it was a God send for me

@ash20453

3 жыл бұрын

Taking lithium myself. It’s been like the equivalent of unlocking the door of the brazen bull and being able to escape. I probably would have already committed suicide had it not been for lithium.

does lithium make the brain heavier?

Carbonate is a posion for brain.

Lithium Orotate?

42 mg is enough 3 times a day. Litarex.

For me, Lithium was hell on earth. I wasn’t in my right mind. I was manic, aggressive, depressed, anxious, hallucinating and had NO Sleep! Basically Hell in the form of a pill. I was so aggressive that the cops had to be called. I’m not usually so aggressive despite having Disruptive Mood Dysregulation Disorder. (DMDD)

@michaelpond813

Жыл бұрын

Use lithium oratate only not the script form.

@youssefgmail7

Жыл бұрын

What type of lithium was it and what was the dose? I bet it was the syntethic litium carbonate form and it was a high dose as prescribed to people with bipolar disorder

@yellowiris123

7 ай бұрын

It's odd that your description of symptoms from lithium are what I had when I was unmedicated bipolar 1. Thanks to zyprexa and lithium, I can function again.

I have bi polar and on 1200mg of Lithium. The worse thing for me it makes me very tired.

@lilm1234

4 жыл бұрын

david jones lethargy and the drowsiness sucks from lithium carbonate.

@Mmmousemaid

4 жыл бұрын

Has your doctor checked your thyroid? Lithium is often given with Synthroid as it suppreses TSH.

@Americalaugher286

2 жыл бұрын

No that’s good stay out of the public that’s working the way it should

Separate each medication from Litarex and tell the truth about each of the binding agents separately in several films.

Help

Absorbtion of lithium by citrate is 100% perfect.

@michaelpond813

Жыл бұрын

Lithium. Oratate not the script kind.

Lithium Citrate has no side effects.

Sounds like a big pain in the ass.

You tell a story as a confused man telling all side effects of everything at once to make us confused.

Lithiumcitrate is not a drug. It is pure 7UP.

Hannibal is multi skilled

And honestly most likely an ex pharmacist. Because I can assure everyone, doctors don’t know too much about medicines and how they help, or make worse in individuals. 😉😛

@tfoxen7518

3 жыл бұрын

Love him. A passionate research guy!

@learnzz9255

Жыл бұрын

He is a Doctor. He says it in his first sentence and its written

Drs

Bipolar ppl seem like story tellers and comedians.

@lenayamamoto

Жыл бұрын

Yeah, on a good day we're fun

I was intrigued how all this doctor talked about was 'people', presumably other people, people other than himself. I would say he wanted to distinguish himself as normal. But, all his face expression was a mystery to me. He was using his mouth excessively to emphasise his words. And moving his head in a rather odd way. To be quite honest I wasn't completely sure if he was being simply sarcastic, or ironic, or whether he even believed what he was saying at all. Or whether he was trying to emphasise his point so much as to be saying 'Don't believe a word of what I am saying.' But as someone who is actually taking Lithium and has been for decades, well let's say 'I wouldn't be making these comments to my GP, or Case worker, or CPN, or psychiatrist. Or for that matter any number of other people, because they wouldn't believe me anyway, would they? They would just be keen to increase my does of medication. It's true isn't it. But he looked to me like he wanted to exaggerate everything, very odd.

The

Lithium oratate plus Neuro. Mag. And omega 3 s. For bipolar. The organic form of lithium oratate is not as toxic as the script form. When combined with Neuro. Mag.

@user-zx5xw4yw2e

Жыл бұрын

💯

You are not honest! Litarex is enough.

42mg 3-4 times a day Litarex. Tevapharm.