Here is a quick video on how to change the CR2016 2016 battery in the Lexus Isuzu Toyota Key Fob. You will need a small screwdriver (PH0) and a pry tool for installation. Also some of this style key also uses a CR1616 battery just make sure you order the correct battery.
LEXUS RX330 1999-2006
LEXUS RX350 2007-2009
LEXUS RX400H 2006-2009
LEXUS RX450H 2010
LEXUS LX470 1998-2007
LEXUS LS400 1997-2000
LEXUS LS430 2001-2006
LEXUS GX400 1998-2000
LEXUS GX470 2003-2008
LEXUS GS430 2001-2005
LEXUS GS400 1998-2005
LEXUS GS300 1998-2005
LEXUS ES300, 1998-2003
LEXUS SC430 2002-2010
LEXUS IS300 2001-2005 (03-05 SEDANS ONLY)
ISUZU AXIOM 2002-2005
ISUZU RODEO 2003-2005
TOYOTA FJ CRUISER 2007-2014
This will also work for various trim levels, just make sure your key fob looks like the one shown in the video. This method also works with the 2 button version.
Battery: CR2016 2016 or CR1616 1616
FCCID: HYQ12BBT, HYQ1512V, N14TMTX-1, N14TMTX1, NI412BBB, HYQ12BBK, HYQ12BBB
Part Number (s): 89070-48821, 89070-60080, 89070-48020, 8907048020, 89785-50031, 8978550031, 89070-60801, 8907060801, 89070-33750, 8907033750, 89070-50170, 8907050170, 1551 102 539, RSS-210
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Lexus Remote Battery Replacement
Keyfob battery change