Ketogenic Therapy: How 3 Patients Put Depression and Anxiety in Remission with Dr. Lori Calabrese

Discover groundbreaking insights from Dr. Lori Calabrese, a Connecticut-based psychiatrist, who recently published a case series demonstrating the complete remission of depression and anxiety in three patients through ketogenic interventions. Dr. Calabrese's case studies offer a "slice of real life," highlighting patients with multiple comorbidities, which is more common than not. She explains how ketogenic therapy can lead to full remission of depression and anxiety, enabling patients to become their best selves, which is rarely achieved with standard-of-care treatments.
In this video, Dr. Calabrese and Dr. Bret Scher delve into the details of her findings, showcasing how a ketogenic diet offers a promising alternative to traditional antidepressant medications.
🔍 In This Video:
Introduction to Dr. Lori Calabrese's work and her recent publication.
Discussion on the effectiveness of ketogenic interventions compared to FDA-approved antidepressants.
Discussion of tracking metabolic markers in psychiatric patients.
Detailed case studies illustrating the impact of diet on mental health.
📢 Key Takeaways:
Ketogenic diets can lead to rapid and sustained remission of depression and anxiety.
Potential for dietary interventions to complement or surpass traditional psychiatric treatments.
The importance of exploring metabolic approaches in mental health care.
Experts in this video:
Lori Calabrese, MD
www.loricalabresemd.com/
Founder and Medical Director of Innovative Psychiatry
Twitter @loricalabresemd
/ loricalabresemd
Studies mentioned:
Complete remission of depression and anxiety using a ketogenic diet: case series
www.frontiersin.org/articles/...
If you or a loved one are looking to begin ketogenic therapy for a psychiatric condition, visit this page for resources:
www.metabolicmind.org/familie...
Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at metabolicmind.org/
About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
Timestamps
0:00 Introduction
1:01 Why Dr. Calabrese looked at keto for depression and anxiety
3:11 Ketogenic therapy intervention design for depression and anxiety
8:29 How often are depression and anxiety put into remission?
10:46 Remission timeline for patients
14:11 What is needed to incorporate metabolic health into psychiatric care
16:42 One therapy to treat brain and mental health
19:37 Is ketogenic therapy for serious mental illness too hard?
22:43 How ketogenic therapy has changed Dr. Calabrese's practice
24:19 Conclusion

Пікірлер: 72

  • @QuasiBlond
    @QuasiBlond22 күн бұрын

    I'm a ketovore for about five years. I am 75 and my mental health HAS NEVER BEEN BETTER. Not only has my anxiety disappeared, but my cognition is great. I feel more in charge of myself now than any previous times in my life. This is true despite having fairly sever residual effects of Guillaine Barré Syndrome that had put me on life support for three months in a state of total paralysis eight years ago. I'm loving this mental clarity. I

  • @henryzhao4622

    @henryzhao4622

    22 күн бұрын

    Hi do you remember if you had anxiety for the first few weeks during the transition?

  • @QuasiBlond

    @QuasiBlond

    22 күн бұрын

    @@henryzhao4622 My mood/anxiety was noticeably improved within a few weeks, but it then continued to get better and better.

  • @theskipgilberto
    @theskipgilberto22 күн бұрын

    No sugar or carbs in weeks for me. I started lifting weights 2 months ago. I was diagnosed with Generalized Anxiety and ADHD 30 years ago. I've lost 40 pounds with my food and exercise plan too!! Best I've felt in a really long time. I still take Buspar and Alprazolam, but I'm starting to feel relief... thank goodness.🙏🙏

  • @henryzhao4622

    @henryzhao4622

    22 күн бұрын

    How long did it take for the no sugar and carbs to help? How long did you feel withdrawal or transition symptoms? Thanks

  • @MrEpsilonZero

    @MrEpsilonZero

    22 күн бұрын

    How did diet help with ADHD!?

  • @kenadams5504

    @kenadams5504

    20 күн бұрын

    ​​​@@MrEpsilonZero Not eating carbs /sugar allows our body to enable our second metabolic state ...a ketogenic metabolic state ,whereby, all our cells are vitalised with ketones .This improves functioning of everything in our body , and helps with conditions like Adhd.(amongst many mental and physical conditions).

  • @theskipgilberto

    @theskipgilberto

    11 күн бұрын

    About 2 months of hard workouts and diet. I'm still medicated. But I feel great. I had a cheat day last week and felt horrible the next day. Just stick with it. Weightlifing has helped me too. Go hard. Negative failure on each set. Good luck. You're not alone. ​@henryzhao4622

  • @theskipgilberto

    @theskipgilberto

    11 күн бұрын

    ​@@MrEpsilonZeroWeightlifting more than diet for ADHD. Tires me out. I feel great.

  • @stephenarkless9444
    @stephenarkless944422 күн бұрын

    All my mental health problems except ocd have disappeared on the carnivore diet I’m no longer on any medications and I was taking a lot!

  • @christianstephens7213

    @christianstephens7213

    8 күн бұрын

    Did you have diet sodas in that time

  • @kassrripples3659
    @kassrripples365921 күн бұрын

    Fantastic… sharing to friends living in assisted living aged care homes… the food they are fed is not fueling their brains and is triggering depression and anxiety.

  • @eulaguider21

    @eulaguider21

    19 күн бұрын

    I was thinking the same the other night. They are consuming lots of carbs and sugar.

  • @naomi8097
    @naomi809722 күн бұрын

    It would be nice to interview patients if they were willing.

  • @cazza993
    @cazza99314 күн бұрын

    Fantastic interview and so good to so much being published on ketogenic diets and mental health. How many years until the ADA is recommending an animal based low carb diet for human health and thriving? How long until this is 'consensus'? I have been sold on this for 10 years but know many skeptics who take the view that until it's in textbooks or the authoritative bodies recommend it it's not worth learning about (because accepted truth changes or some such)

  • @sgtcoach62
    @sgtcoach628 сағат бұрын

    knowledge is power!!!

  • @joecaz
    @joecaz22 күн бұрын

    Very inspiring! and exciting! and hopeful!

  • @johnbrain3960
    @johnbrain396019 күн бұрын

    Does keto help if depression and anxiety are hereditary? I have insulin resistance, diagnosed a year and a half ago, and 3 months ago the anxiety returned. I will try Keto.

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    Trying psychedelics will help you in your fight against anxiety and depression the way it did with me, and I get my stuff discreetly from a source that sells the best shrooms dmt, LSD, mdma, edibles and many more

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    Pharmpsych4

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    On Instagram

  • @danscieszinski4120
    @danscieszinski412022 күн бұрын

    I did keto for 15 years and was the clearest health wise I’ve ever lived. Lost weight, all mental complaints disappeared. Then suddenly I started getting low blood sugar problems and started eating “normal” carb levels again but no grains. It corrected the low blood sugar episodes but I am no longer in ketosis and I have mood issues again. Why would after 15 years my blood sugar lows start on strict keto?

  • @jayb2175

    @jayb2175

    21 күн бұрын

    Not enough protein maybe?

  • @Hertz2laugh

    @Hertz2laugh

    21 күн бұрын

    What were the low blood sugars testing at? What symptoms were you having?

  • @danscieszinski4120

    @danscieszinski4120

    20 күн бұрын

    @@Hertz2laugh some around 60. I can tell when my heart starts skipping and I get shaky and concentration goes to crap.

  • @gsts379

    @gsts379

    17 күн бұрын

    Things that might have affected your long term ketogenic lifestyle: Low electrolytes? Too much protein and not enough fats? What changed then - life stressors, adding low carb bread, changes in exercise? Hope you figure out something that helps.

  • @motorsoph6994
    @motorsoph699422 күн бұрын

    Your half way there with the keto diet but it works because your not feeding candida what it loves to eat = sugar, carbs, yeast!! You need to consume antimicrobials too to kill the overgrowth of candida and get it back down to normal levels in the body. Candida took over my body after i was prescribed diazepam, codeine and naproxen all at the same time when i hurt my arm. I was also consuming sandwiches and cake bars for work everyday. I started suffering uncontrollable panic attacks out of nowhere a year ago. 3 weeks ago I started a candida cleanse which is very similar to keto(no sugar, carbs, gluten, wheat, processed food) and I am completely back to my normal self again. Candida has 79 toxins which wreak havok with the brain. I just wish my doctor told me this rather than advising i went of antidepressants.

  • @jayb2175

    @jayb2175

    21 күн бұрын

    That doesn't mean everyone has candida because you did.

  • @motorsoph6994

    @motorsoph6994

    21 күн бұрын

    @jayb2175 I'm not saying they do. But it's strange how eating one sugary snack or one sandwich can make the symptoms come back again. Like you're fuelling something to attack your brain again. Not many people will want to live on a ketogenic diet forever. I have lived on sugar and carbs for 30 years of my life just fine until panic disorder rocked my world a year ago. What made my body/brain change like that and funny how it changed after I was prescribed a concoction of drugs from the hospital to kill of my good gut bacteria.

  • @joeberrouard3743

    @joeberrouard3743

    14 күн бұрын

    Which antimicrobials did you use?

  • @motorsoph6994

    @motorsoph6994

    14 күн бұрын

    I started taking natural ginger and allucin(garlic) supplements every night. I noticed a massive improvement within a couple of days. That's how I knew it was yeast as they are antimicrobials. Also magnesium supplement seemed to get rid of the dizziness I was experiencing all day. I then added in grapeseed extract and probiotics everyday. Drinking 2 litres of filtered water everyday too. That is what helped me personally.

  • @joeberrouard3743

    @joeberrouard3743

    14 күн бұрын

    @@motorsoph6994 thanks for the response!

  • @Merzui-kg8ds
    @Merzui-kg8ds7 сағат бұрын

    I have been keto or low carb for (most of) about a decade. The hardest part of sustaining keto is having to prepare every meal every day. It is expensive, time consuming, and exhausting. Keto "prepared" products that are available in stores are almost all nutritional garbage. If keto is to become a realistic intervention widely used, there needs to be a realistic way for people to afford the time and the cost of sustaining the intervention. Giving up carbs is the easy part. Cost and hours devoted to food prep are the unsustainable parts.

  • @effiepatricia3610
    @effiepatricia361021 күн бұрын

    I 'm in ketosis now for 3 full days. So far I could not experience changes regarding my OCD/ depression. But I feel more awake and fitter. After which time period can one expect improvements, if at all? 1 month, 3 month? Thank you.

  • @bridgethollandsworth2138

    @bridgethollandsworth2138

    19 күн бұрын

    Give it a try for atleast 90 days. It takes everyone different time.

  • @effiepatricia3610

    @effiepatricia3610

    19 күн бұрын

    @@bridgethollandsworth2138 Thank you. Yes, that makes sense.

  • @danielbartok9989
    @danielbartok998921 күн бұрын

    How were the therapeutic drugs handled during the ketogenic therapy??

  • @metabolicmind

    @metabolicmind

    21 күн бұрын

    That's going to be different for each individual. Here's a video we made that goes into more detail about handling psychiatric medications with ketosis. We hope it helps! kzread.info/dash/bejne/lomtwZOPh5qfZ84.html

  • @user-zh9sq2zk3v
    @user-zh9sq2zk3v22 күн бұрын

    In regard to my son with schizophrenia, one thing I cannot advise him on is how to reduce sugar, knowing that artificial sweeteners seem to be bad for the body. Recently the OOBLI sweetener made from proteins was introduced. Can you give an opinion as to the metabolic effect of this sweetener on ketogenic therapies?

  • @metabolicmind

    @metabolicmind

    22 күн бұрын

    The most common sweeteners used by people in ketosis seem to be allulose, monk fruit, and erythritol. There has been some bad press recently around erythritol, so it seems people are leaning more toward the first two.

  • @kathyhebert1651

    @kathyhebert1651

    21 күн бұрын

    I use Allulose😊

  • @brianhamilton811
    @brianhamilton81122 күн бұрын

    For someone who won't try a keto diet, would adding sufficient MCT oil to the diet accomplish the same thing?

  • @metabolicmind

    @metabolicmind

    22 күн бұрын

    Good question. We interviewed Dr. Mary Newport about her experience using coconut oil and MCT oil for her husband's dementia. kzread.info/dash/bejne/pGdhl6mKlsiwZps.html It seemed to work well for him. But he was also eating a low-carb diet, even if it wasn't a true ketogenic diet. So, if someone was eating a very high-carb diet and adding MCT oil, it may not have the same effect as someone eating a relatively low-carb diet and adding MCT oil. We still have more to learn through research, but there's always the question of asking, is it worth trying? For many the answer is yes.

  • @henryzhao4622
    @henryzhao462222 күн бұрын

    Anyone else feel more anxious for the first few weeks on keto? Hope it’s not just me

  • @QuasiBlond

    @QuasiBlond

    22 күн бұрын

    I was nervous about doing the diet as I was being told how unhealthy it was. Also, getting my electrolytes sorted out was a bit dicey at times and I didn't feel so good when that was happening.

  • @lynndecarlo6704

    @lynndecarlo6704

    22 күн бұрын

    That's more of the energy you feel when getting rid of the carbs. I always felt lethargic after carbs.. I started keto and was waking up with so much clarity and energy it can definitely be mistaken for other things.

  • @juleslinnie4702

    @juleslinnie4702

    22 күн бұрын

    exercise if important and so is LMNT type electrolytes. Helped me or eat snack of celery and almond butter

  • @henryzhao4622

    @henryzhao4622

    22 күн бұрын

    @@juleslinnie4702 thanks yes ive focused on those a lot too! did you happen to feel some sleep difficulty the first few weeks though? I've read that cortisol spikes the first few weeks to create sugar to compensate before it normalizes, but its tough

  • @raqueldubya2981

    @raqueldubya2981

    22 күн бұрын

    I am only 9 days in and had some really bad anxiety spikes the first couple of days. I have rationalised that I already had severe anxiety with really severe anxiety spikes before keto and that I am just noticing them more as part of my ingrained hypervigalence. Years of experimenting with traditional anxiety/depression medications have also made me ridiculously anxious around what any kind of new treatment is going to do to me and means I am constantly checking in and analysing anything and everything, good or bad. I also suspect that my body and my brain are going through a lot of adjustments with the diet change and that things will take time to settle and for there to be real solid progress. Not sure about you, but I have been very unwell with anxiety for a few years now and I think a keto diet is not going to be a quick fix. It took me years to get to where I am and it's going to take time to heal. Wishing you good luck with your keto journey.

  • @mariamorris954
    @mariamorris95415 күн бұрын

    Anyone consuming fermented food,? My anxiety is pretty high Keto with Natto/fermented veg's might be the answer for me

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    Psychedelics was of profound help to me during my depression and anxiety stage,I was referred to a mycologist that acted as a therapist and he hooked me up with some psychedelics that aided the fight against my issues

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    Pharmpsych4

  • @SandraQueen-vm8hh

    @SandraQueen-vm8hh

    15 күн бұрын

    On Instagram

  • @lmagas-om9dp
    @lmagas-om9dp22 күн бұрын

    Does keto help ADHD?

  • @NoTrashInHeaven

    @NoTrashInHeaven

    22 күн бұрын

    I've heard many testimonials of those with ADHD say yes!

  • @meihsieh4440

    @meihsieh4440

    22 күн бұрын

    Yes! It helps ADHD, decreased Seizure activity and else. I’ve witness those 🙏🏻❤️

  • @metabolicmind

    @metabolicmind

    22 күн бұрын

    Here's a video we did about an upcoming study on keto and ADHD from Ally Houston. We hope that helps! kzread.info/dash/bejne/pYl1xNORk7anqso.html

  • @gabardjean-paul3779
    @gabardjean-paul377922 күн бұрын

    3 patients . rather small cohort !

  • @gsts379

    @gsts379

    17 күн бұрын

    That addressed at the beginning of the video. This was a case study not a trial.

  • @joe-zp7ge
    @joe-zp7ge20 күн бұрын

    if you start the keto and your anxiety subsides.... will it return when you stop eating keto? to stay on the keto indefinitely is unrealistic and wishfull thinking

  • @metabolicmind

    @metabolicmind

    20 күн бұрын

    We would push back a little on "to stay on the keto indefinitely is unrealistic and wishfull thinking." For those who have put their anxiety, OCD, bipolar disorder, etc, into remission, keto is not a chore at all. There's no question that for some people it can be challenging. But others have stayed in ketosis for years and decades without an issue. It's probably something people need to experience before deciding if it is possible or not.

  • @Merzui-kg8ds

    @Merzui-kg8ds

    7 сағат бұрын

    @@metabolicmind I wonder if those who stay on keto are receiving financial and cooking assistance to mitigate the expense and amount of work it is to sustain keto. To stay keto while employed full time is quite a challenge, due to meal prep consuming a lot of time and energy.

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