Ionizable Amino Acids

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Пікірлер: 68

  • @blabber9093
    @blabber90933 жыл бұрын

    If you don't have one, you should consider doing an MCAT/DAT prep series. Your videos come highly recommended by many MCAT test-takers! Also, I showed my medical school professor & he said these are some of the best videos he's seen. Thank you!

  • @hasaniqbal5993

    @hasaniqbal5993

    3 жыл бұрын

    this comment needs more likes

  • @pinkpegasus6313

    @pinkpegasus6313

    2 жыл бұрын

    yes omg ^^ kind of like chad's prep!

  • @nilphite
    @nilphite4 жыл бұрын

    pH vs pKa is like a battle between solution and molecule for a proton. If pH is higher than pKa, solution wins the proton. If the pKa is higher than the pH, the molecule wins the proton.

  • @johnnyace1300

    @johnnyace1300

    3 жыл бұрын

    to the top!

  • @momijithelesbianleftie6578

    @momijithelesbianleftie6578

    2 жыл бұрын

    How barbaric! Such conflict. Can also see it as different states of equilibrium. Or like a dance between atoms, one moment there might be some EDM with a nice thicc bass playing, and all the hydrogen atoms are like total BASE sluts so the electrons wanna hang out with arginines, C, carbon atom instead because C stands for Cool as fuck. And when the environment is more acidic, like theres some GOA playing and everyone starts dancing far too much, the electrons return to sulfur. Because sulfur sells all the 'dangerous' chemicals the electrons wanna get high on.

  • @amaduconate5262

    @amaduconate5262

    2 жыл бұрын

    @@momijithelesbianleftie6578 😃😃😃😃 crazy analogy you got there. Probably the best definition/analogy about about pKa/pH equilibrium

  • @kschleeps
    @kschleeps5 жыл бұрын

    I have NEVER watched a video on a subject that I struggled with and completely understood it in 8 minutes. You are so nice. Thank you.

  • @tiffanymartinez-lapa2654
    @tiffanymartinez-lapa26546 жыл бұрын

    Yep, I Love You! So articulate and informational.

  • @euscieu4246
    @euscieu42467 жыл бұрын

    Thank you so very much! You help me gather my ideas and organize them in a concise way. More people should know about you. Keep it up :D You're doing a great job at teaching

  • @marcx3lla
    @marcx3lla5 жыл бұрын

    this was EXACTLY what I was looking for. thank you so much.

  • @andrew_wayne
    @andrew_wayne4 жыл бұрын

    this was EXACTLY what I was looking for. thank you so much.You sir, are an amazing. Thank you so very much! You help me gather my ideas and organize them in a concise way. More people should know about you. Keep it up :D You're doing a great job at teaching

  • @victoriafernandez4827
    @victoriafernandez48273 жыл бұрын

    This is the most underrated science channel ever.

  • @swinkadoodaleeday
    @swinkadoodaleeday6 жыл бұрын

    You sir, are an amazing explainer

  • @ccubillo11
    @ccubillo115 жыл бұрын

    Love your videos. Exceptional clarity.

  • @joslypierre-louis3046
    @joslypierre-louis30465 жыл бұрын

    Thank you so much for this video! Exactly what I needed!

  • @cognitivenicnac
    @cognitivenicnac7 жыл бұрын

    Clear and concise thank you and God bless.

  • @alisaabary5224
    @alisaabary52246 жыл бұрын

    i was relooking all over for this vid just because i forgot to like it. thank you sir!

  • @nabeelshafi6159
    @nabeelshafi61593 жыл бұрын

    that was the best thing ive ever seen

  • @prathimakannan2489
    @prathimakannan24892 жыл бұрын

    Exactly what I needed - thank you

  • @MD-vu9yy
    @MD-vu9yy5 ай бұрын

    THIS MAN IS A GENIUS THANK YOU SO MUCH

  • @abigail9734
    @abigail97345 жыл бұрын

    Helpful. Thank you.

  • @anaherrera4805
    @anaherrera48052 жыл бұрын

    the best biochemestry videos!

  • @ayubeawel9301
    @ayubeawel93015 жыл бұрын

    nice & helpful lecture, thank you

  • @igalbar7815
    @igalbar78155 жыл бұрын

    amazing explanation!

  • @lullabymemo8520
    @lullabymemo85206 жыл бұрын

    Your lectures are very useful, but where I can find how to find pi value for single amino acid?

  • @natestroud3299
    @natestroud32994 жыл бұрын

    Thanks for teaching us, daddy.

  • @karenserdenairri4874
    @karenserdenairri48745 жыл бұрын

    Hi i just want to ask what happened to the benzene ring of tyrosine? Why it became cyclohexyl?

  • @jingyi989812
    @jingyi9898126 жыл бұрын

    Thank you so much

  • @utem7511
    @utem75116 жыл бұрын

    u r just all I need for every subject🙏👍👍👍👌👏

  • @Hussain_Safaa
    @Hussain_Safaa7 жыл бұрын

    thank you bro >> god bless U

  • @youareenough6148
    @youareenough61482 жыл бұрын

    Sir, what you did in the last structure? Are u inonised the both amino gp or the single one???

  • @sonya1500
    @sonya15005 жыл бұрын

    thank you so much!!!!

  • @KenyaTeam2011
    @KenyaTeam20116 жыл бұрын

    Forgot your double bonds in the second tyrosine drawn :)

  • @yousefmustafa1230
    @yousefmustafa1230 Жыл бұрын

    Thanks you for explained 🤍. But what if the Ph equal to Pka which side conjugated acid or base?

  • @jackiedo1671
    @jackiedo16718 жыл бұрын

    Excellent, very clear. Preparing me for biochem at UCLA- thank you :-)

  • @irfanalimsstudentchemicale7324
    @irfanalimsstudentchemicale73242 жыл бұрын

    any one know the answer please reply me. If we are doing electrodialysis for peptide separation so which are made during this electrodialysis?

  • @SanjoyShome
    @SanjoyShome3 жыл бұрын

    I wish he teaches us in our school.

  • @zexicc
    @zexicc3 жыл бұрын

    What happens with serin?

  • @devilboii96
    @devilboii964 жыл бұрын

    Hi, great video. But what's with Histidine, how do you explain that it is positively charge at normal physiological pH?

  • @Rose-mg5eq

    @Rose-mg5eq

    3 жыл бұрын

    It is not positively charged at physiological pH, that is a misconception. It is the only basic amino acid that is actually not positive at pH 7

  • @rachel39321
    @rachel3932111 ай бұрын

    i saw that the pI of cysteine is 5.07 and now i'm so confused. does this mean it is usually deprotonated at physiological pH? cause pH>pI means the molecule is mostly deprotonated. right? does anyone know? i've watched so many youtube videos looking for the answer.

  • @bawanomer1244
    @bawanomer12443 жыл бұрын

    Thanks

  • @dominiqueturner1772
    @dominiqueturner17725 жыл бұрын

    Can someone help me with this question?? I can't seem to figure it out! Please and thank you!! How many functional groups does the peptide MDFGRKCDE have that can be titrated?

  • @LegitPRZ

    @LegitPRZ

    5 жыл бұрын

    6 functional groups. You basically have to look at all of the side chains which can be ionized. In this case: Aspartate (Dx2), Arginine (R), Lysine (K), Cysteine (C), and Glutamate (E)

  • @doubledoggo5668
    @doubledoggo56686 жыл бұрын

    Why is the pKa of the alpha carboxyl less than the pKa of the side chain carboxyl?

  • @Annechenyac

    @Annechenyac

    3 жыл бұрын

    there is a mutual repulsion between the positive charge on the alpha- NH3+ and the H+ on the alpha carboxyl group that make the pKa of the alpha carboxyl group lower. lower pKa = easier to lose H atom. hope this helps.

  • @naviddarayan101
    @naviddarayan1019 жыл бұрын

    Why is Tyrosine found within the protein away from water? my understanding is that it can hydrogen bond at physiological pH?

  • @sentinel7778

    @sentinel7778

    7 жыл бұрын

    navid darayan Yeah you're right. This is what i've understood too. Tyrosine is supposed to be a polar amino acid due to the OH present that can form Hydrogen bonds.

  • @DapaChrons

    @DapaChrons

    4 жыл бұрын

    you prolly don't need this information anymore, but for anyone who looks at your question: tyrosine has a massive six-member carbon ring that keeps it hydrophobic. But its oxygen makes it slightly more polar than phenylalanine for example. If you look at tyrosine's structure compared with serine, threonine, asparagine, glutamine, cysteine, etc., it will make sense

  • @uyenthinguyen6447
    @uyenthinguyen64472 жыл бұрын

    How come the general pka value for the carboxyl + amine terminus is 3.1 or 8? My textbook has a variety of pka values for each of the 20 amino acid. Can anyone explain the difference?

  • @kimberlysanchez6693

    @kimberlysanchez6693

    Жыл бұрын

    did you find out the difference? having the same issue/question

  • @rassimsimou1594
    @rassimsimou15949 ай бұрын

    Good

  • @ayeshasahar4772
    @ayeshasahar47725 жыл бұрын

    You didn't clear what is actually Pka value? 😐😯

  • @youareenough6148
    @youareenough61482 жыл бұрын

    If the last two structures are clear to some one then pls explain those structures to me also

  • @mariamshahzadi3796
    @mariamshahzadi37963 жыл бұрын

    Hi ! I would like to inform you about your vedio presentation that some tecneque for better perspective... Actually when you delevior the presentation so three points you should keep it on your mind that your writing partent must be clear for vesual empire and other common person and the secont point to mention on here that when you explaination about any topic so if you need the rough work by methamically assess ways so do it and make the coloum on the right side by best ways for better understand what are you explaination . right now i am attending your presentation about the topic ( amino acids and proteins from physics aspects ) so firstly i am extemly sorry about your writing I am hardly saw your written work if some one new to join your channel so how can he / she learn by these ways by verbaly you are doing nice job. thanks for delevers such choose the very effectic topic . thanks

  • @SANDRA-ho2xu
    @SANDRA-ho2xu6 жыл бұрын

    what is the average length of magnesium? Im really struggling to find an answer

  • @AlfaHanen1
    @AlfaHanen17 жыл бұрын

    The best that what YOU are. :)

  • @lanavujica4799
    @lanavujica47994 жыл бұрын

    I LOVE YOU

  • @mizzannie001
    @mizzannie0015 жыл бұрын

    love you

  • @AKLECTURES

    @AKLECTURES

    5 жыл бұрын

  • @udaykiranvadde9572
    @udaykiranvadde95723 жыл бұрын

    India ❣️💓💞💕America ❣️💖💕❣️💞💖

  • @marvinbrightyoung2520
    @marvinbrightyoung25205 жыл бұрын

    why we have to sit in the classroom and listen to someone who doesn’t know what it is talking about.lol.

  • @zeyaley13
    @zeyaley133 жыл бұрын

    he is talking TOO FAST. i watched some parts at the speed of 0,75

  • @Sunshinelovepeach
    @Sunshinelovepeach4 жыл бұрын

    marry me

  • @sja5385
    @sja53852 жыл бұрын

    I hate chemistry