Inflammation and the Metabolic Response to Injury

What is the metabolic response to injury and trauma? How does the body respond to pain?
What cascades are initiated by hypovolemia and hemorrhagic shock?
What about all of those circulating hormones and cytokines following injury?
MUST HAVE SURGERY BOOKS
Sabiston's Textbook of Surgery citizensurgeon.co/Sabiston
Moore's Clinically Oriented Anatomy citizensurgeon.co/Moore
Netter's Anatomical Atlas citizensurgeon.co/Netter
Schwartz Principles of Surgery citizensurgeon.co/Schwartz
Fischer's Mastery of Surgery citizensurgeon.co/Mastery
Zollinger's Atlas of Surgical Operations citizensurgeon.co/Zollinger
Top Knife (MUST MUST HAVE) citizensurgeon.co/topknife
Sign up and join the CITIZENSURGEON Community: citizensurgeon.co/signup
Welcome back friends! In this tutorial we'll take a deep dive into the Metabolic Response to Injury and Trauma. It's a difficult topic and this is a pretty long video so I've provided some shortcuts below!
WHAT YOU ARE GOING TO LEARN
1.). The THREE major factors involved in the body's metabolic response to injury
2.). The hormones critical in the injury response
3.). The most important cytokines involved in injury and their function
FAST FORWARD WITH THESE TIMESTAMPS
Start 00:00
Goals for Understanding 01:14
Why are we learning about the Metabolic Response to Injury 02:00
What are the 3 Major Stimulants of the Body's Response to Injury 02:40
Pain, Fear and Anxiety and Related Hormones 03:11
Hypovolemia, Baroreceptors and Feedback Loops 05:20
Circulating Hormones, Cytokines and Interleukins 08:05
An Awesome Table for Hormones 08:37
Autonomic Nervous System and the Body's Response to Injury 13:32
RAA Axis, Glucagon and Insulin 15:49
Another Awesome Table for Cytokines 18:21
Summary and Tying it All Together 21:02
BE MY FRIEND
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WHO AM I?
I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a weekly newsletter called the Saturday Six where I identify Six different discoveries of the week. You can get the weekly newsletter by signing up to the CITIZENSURGEON Community!
REFERENCES
Norton's General Surgery Textbook - citizensurgeon.co/Norton
DISCLAIMER
While my aim is to help educate you for the ward, the surgical ICU, the operating room and your exams remember these videos are not a replacement for your reading, your medical school and residency preparation and most important your own decision making. Good luck and enjoy!
Affiliate Links - There are a few links in the description that may lead to a kickback to me to help support the channel.

Пікірлер: 106

  • @the0master200
    @the0master2004 жыл бұрын

    I am a surgical resident preparing for my exams, finding your channel is a blessing. please keep it up.

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    the0master200 great to hear, good luck with your exams! More topics on the way if there is anything you want to hear about definitely let me know

  • @the0master200

    @the0master200

    4 жыл бұрын

    @@citizensurgeon Thank you so much Dr. You are so kind. Well, I'd suggest continuing with the basics, such as, surgical infection, pre-operative planning and post-operative care, and surgical critical care and bedside procedures.

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    the0master200 certainly, the next video is planned for bleeding, transition and Hemostasis, surgical infection and wounds to follow. Great idea for bedside procedures, thank you!

  • @the0master200

    @the0master200

    4 жыл бұрын

    @@citizensurgeon you are welcome Dr. I appreciate your rapid responses and willingness to teach. Looking forward to your future videos.

  • @rebbekandahuma2173

    @rebbekandahuma2173

    2 жыл бұрын

    Hi, so what do you wanna specialize in? I wanna become a surgeon too and rn I’m a third year medical student 🙃

  • @dr.alishmehta3104
    @dr.alishmehta31044 жыл бұрын

    Thank you sir for this wonderful video. I'm a second year post graduate student of general surgery in India. I never understood this topic so well. Thank you for making this simplified. Looking forward for more such surgical educational videos.

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    Alish Mehta I’m so happy you enjoyed it! More on the way!

  • @ricksanchez7965
    @ricksanchez7965 Жыл бұрын

    Dr, I'm more then thankful and surprised that you put every important piece of information regarding the topic in just under 25 minutes, you truly are a genius!

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Thanks for such an awesome and supportive comment, that was my first video now over two years ago and it continues to be a good one! Such an important topic! Let me know what else you would like to learn…

  • @DTheDuude
    @DTheDuude3 жыл бұрын

    I’m writing a paper for A&P 2 and i just wanted to thank you for answering questions I wasn’t able to find!

  • @kenkel9184
    @kenkel9184Ай бұрын

    This should be patented, laminated & sold.... Never seen a summary that cleared so much confusion. Thank you sir!...Absolutely succint!...

  • @citizensurgeon

    @citizensurgeon

    Ай бұрын

    Love that! Thank you! I think it’s time for an update!

  • @JEFFLAKRONIA1
    @JEFFLAKRONIA13 жыл бұрын

    Thank you so much doctor I have watched this and then read the chapter from Bailey and Love .. awesome I really like your simplification of complex concepts

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    JEFFLAKRONIA1 thanks so much for the feedback, it’s definitely an overwhelming topic and I’m glad the talk made it a little more clear!

  • @user-ng5cp2mu9w
    @user-ng5cp2mu9w7 ай бұрын

    Your clear explanations rescued me from confusion. Thank you!

  • @citizensurgeon

    @citizensurgeon

    7 ай бұрын

    I love that so much!!

  • @tariqhassan7306
    @tariqhassan73063 жыл бұрын

    U totally nailed it. Love for this ...

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Love that! Sorry for the delayed reply somehow I missed this! Thank you. If there is anything you want to learn please let me know!

  • @jplayah5264
    @jplayah5264 Жыл бұрын

    I'm not even a medical student and I learned a ton from this. Thank you!

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Awesome, pumped that you enjoyed it!

  • @malithjuraghok
    @malithjuraghok Жыл бұрын

    thank so much Doctor for this well elucidated lecture.

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Awesome thank you for the feedback!!

  • @prokastinatore
    @prokastinatore6 ай бұрын

    It's a breathtaking damn perfect summary! Thank you so much!

  • @citizensurgeon

    @citizensurgeon

    6 ай бұрын

    Thanks so much! First video I ever did :)

  • @djanorlartey918
    @djanorlartey9184 жыл бұрын

    Thanks for making this so simple!

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    Thank you for the feedback! It’s definitely a complicated topic that comes down to just a couple of main players. I’m very happy to hear that it was helpful!

  • @drtuhin
    @drtuhin4 жыл бұрын

    Thanks sir, please continue.

  • @EJDin
    @EJDin3 жыл бұрын

    Thank you so much for this doc!!! Definitely helped me in studying for my exam

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Hope the exams continue to go well!!

  • @zadranakhan8366
    @zadranakhan83666 ай бұрын

    Really amazing helpful ,keep posty❤

  • @citizensurgeon

    @citizensurgeon

    6 ай бұрын

    Awesome so excited you loved it!

  • @jomzski27
    @jomzski273 жыл бұрын

    I’m a 2nd year medical student, I just now found out about your channel doc! Thanks! And stay safe

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Awesome thanks so much for the feedback, if there is a topic you want to learn about let me know. I have a few talks ready to post!

  • @NarutoUzumaki-tq6wp

    @NarutoUzumaki-tq6wp

    3 жыл бұрын

    I think you're a Filipino, just like me. High five dude!

  • @NarutoUzumaki-tq6wp

    @NarutoUzumaki-tq6wp

    3 жыл бұрын

    @@citizensurgeon Please talk about neurologic cases (common cases such as traumatic head injuries), Thyroid disorders, Gall bladder disorders, and any common emergency cases as well. It would be a great help if you'll discuss it Sir since these are common in our setting. Thank you!

  • @adilhusain8826
    @adilhusain88263 жыл бұрын

    Thanks for this wonderful lecture sir.

  • @aymanfouad1163
    @aymanfouad11632 жыл бұрын

    Billions of thanks for this magnificent summary for metabolic response

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Wow, thanks so much, this type of feedback gives me the fuel to make more content. I certainly appreciate it. What topic do you want to hear about next?

  • @uafridi1179
    @uafridi11793 жыл бұрын

    Thank you 👍🏼

  • @QabasAbdAllah-qe1nt
    @QabasAbdAllah-qe1nt16 күн бұрын

    Perfect 🙏💯

  • @roselin4087
    @roselin40874 жыл бұрын

    thank you very much sir for this wonderful video

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    rose lin I’m glad you enjoyed it, more to come!

  • @paromitasarker151
    @paromitasarker1513 жыл бұрын

    So glad i found your channel 🤗🤗

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Paromita Sarker totally awesome thanks for the feedback!

  • @abdiazizwaasuge5162
    @abdiazizwaasuge51624 жыл бұрын

    Thank you Dr Erick pearson You helped me understand

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    Abdiaziz Waasuge thank you for the feedback! Part three coming up this week. If there is anything I can do to make them better let me know!

  • @estherf6242
    @estherf6242 Жыл бұрын

    Thank you so much for this, Dr!

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Absolutely! Hope it helped!

  • @tempo8785
    @tempo87852 жыл бұрын

    Thank you so much for this beautiful lecture ❤

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Thanks so much for the feedback I’m happy you enjoyed it!

  • @albertorobles6273
    @albertorobles62733 жыл бұрын

    Thank you

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Absolutely! Glad you enjoyed it! If there is another topic you would like let me know. Be safe. Be well!

  • @dostmuhammad2944
    @dostmuhammad29442 жыл бұрын

    Thank u

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    You are welcome I’m so glad you enjoyed it! Sorry for the late reply!

  • @oluwaseyiadeoye2627
    @oluwaseyiadeoye26273 жыл бұрын

    Thank you so much for this video. Now I can read the topic without having a headache 😂😂

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Thank you so much! This is the type of feedback that keeps me pumped up and excited to make more videos! Let me know if you have any topics you would like covered!

  • @KHOISANKING
    @KHOISANKING3 жыл бұрын

    Thank you for being more than my college lecturer

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    That’s awesome thanks for the feedback!

  • @fabianazaninotti2176
    @fabianazaninotti21763 жыл бұрын

    Thanks for all this info!!! 🙌🏼🙌🏼

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Fabiana Zaninotti you are welcome!

  • @natashavs
    @natashavs3 жыл бұрын

    This lecture really helped filling in the gaps, Thank you! 🙏🏻

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Absolutely! Thanks for watching, tell your friends!

  • @muqtadaqutaiba2882
    @muqtadaqutaiba28823 жыл бұрын

    Subscribed, fantastic lecture and great channel! Thank you, Doctor.

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Thank you for the feedback! And welcome, let me know if there is a topic you want to learn about!

  • @muqtadaqutaiba2882

    @muqtadaqutaiba2882

    3 жыл бұрын

    ​@@citizensurgeon Thank you for the kind words, I'm honored. So far, everything I needed to for the first semester is already covered here which is great! For the second semester which will be starting in the next month, I would absolutely love to prepare myself with your fantastic lectures, so if you can do any of the following topics, that'd be great! -Oncology (principles) -Surgical Anastomosis -Vascular Surgery -Burns Thank you!

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    @@muqtadaqutaiba2882 you got it, should be able to hit a couple of those!

  • @najatbenhasan8725
    @najatbenhasan8725 Жыл бұрын

    Thank you for this wonderful lecture

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Thank you so much for the feedback!

  • @ngwuarinze6209
    @ngwuarinze6209 Жыл бұрын

    Thanks Doc

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    You are welcome!

  • @monakanwal378
    @monakanwal3784 жыл бұрын

    Amazing doc gud job

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    Mona Kanwal Thanks for the feedback Mona, recording Surgical Nutrition today and should have it out by tomorrow!

  • @saharhaider1908
    @saharhaider19082 жыл бұрын

    It is so good , Thank you

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    So glad you enjoyed it!

  • @messiwhatasppstatus3982
    @messiwhatasppstatus39822 жыл бұрын

    Thank you sir 🙏 ☺

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    You are welcome, fever series coming this week!

  • @messiwhatasppstatus3982

    @messiwhatasppstatus3982

    2 жыл бұрын

    @@citizensurgeon thank you sir... I'm from India 🇮🇳. Can you cross the whole chapters of surgery one by one.. if its lengthy videos .. its ok for us . Actually I saw ur last video on 2 months ago.. that time I'm so little bit up set. Now I'm happy sir ☺ 😊

  • @afiak739
    @afiak7394 жыл бұрын

    Omg thank youuu

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    Awesome! So glad you enjoyed it. The next video on bleeding disorders will be out tomorrow!

  • @afiak739

    @afiak739

    4 жыл бұрын

    Doing a rotation in surgery in Ghana had to give a presentation on this topic today ... your video saved me😊. Am hooked

  • @user-jq9wz7ld7f
    @user-jq9wz7ld7f2 жыл бұрын

    U are the best

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Awesome! Thanks!

  • @relaxingsounds8582
    @relaxingsounds85822 жыл бұрын

    dr u mentioned that glycolysis is anabolic process and it is inhibited during injury which it is wrong

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Thanks for the feedback, do you have the time stamp I mentioned that? My apologies if I made a mistake, glycolysis is certainly catabolic!

  • @hadeelahmed9217
    @hadeelahmed9217 Жыл бұрын

    Thanks for this great channel Is evernote pediatric surgery note is public ?

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Thank you! It’s not public but I would definitely encourage you to find a few mates and create your own. A huge part of the value is creating what you think is important! Good luck with your studies!!

  • @malakhroub8697
    @malakhroub8697 Жыл бұрын

    This is wonderful, thank you! :).... Allow me to correct an info: Arterial baroreceptors are located within the carotid sinuses not the carotid body

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Thank you for the correction Malek!

  • @the0master200
    @the0master2004 жыл бұрын

    I have one comment to make as feedback, please try to make the videos have higher volume, my phone and laptop both can't seem to be loud enough for me to hear you clearly.

  • @citizensurgeon

    @citizensurgeon

    4 жыл бұрын

    the0master200 that is fantastic, thank you for letting me know, learning how to edit :)

  • @the0master200

    @the0master200

    4 жыл бұрын

    @@citizensurgeon appreciate it Dr.

  • @theorenda3841
    @theorenda38412 жыл бұрын

    Please increase the volume in further videos.

  • @citizensurgeon

    @citizensurgeon

    2 жыл бұрын

    Thanks for the technical feedback! Much needed! I can say that the early videos on 20/21 were low on the volume side and too much background music/noise, I think now I have it dialed in :)

  • @richellemarizdimatulac2557
    @richellemarizdimatulac25573 жыл бұрын

    Thank you so much for this channel, doctor! This is a huge help in my preparation for my board exams :) P.S. I'd just like to respectfully point out the ff (based on berne & levy's physiology textbook): aortic and carotid BODY = peripheral CHEMOreceptors aortic and carotid SINUS = BAROreceptors

  • @Anonymous-mf1cu
    @Anonymous-mf1cu Жыл бұрын

    sadly i can't get acces to the Evernote page, it says 'error' please help

  • @citizensurgeon

    @citizensurgeon

    Жыл бұрын

    Oh dang, I’ll fix that!

  • @Anonymous-mf1cu

    @Anonymous-mf1cu

    Жыл бұрын

    @@citizensurgeon thanx, let me know please when you update it that page would save my life, appreciate it.

  • @SG-yn1qj
    @SG-yn1qj9 күн бұрын

    6:00

  • @Riano1989
    @Riano19892 ай бұрын

    👌👌👌👏👏👏🙏🙏🙏

  • @citizensurgeon

    @citizensurgeon

    2 ай бұрын

    Thanks so much! An oldie but a goodie, gotta make an update!

  • @allahhabibi591
    @allahhabibi5912 жыл бұрын

    The music distracts my attention so annoying 😭🥲

  • @Kailash7982
    @Kailash79824 жыл бұрын

    Thank you

  • @citizensurgeon

    @citizensurgeon

    3 жыл бұрын

    Absolutely! Glad you enjoyed it!