How To Prevent Post Finasteride Syndrome | The Gillett Health Podcast #12

James O'Hara NP, determines how to potentially prevent PFS and what to look for if you think you have it.
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Пікірлер: 46

  • @rickycarvalho4883
    @rickycarvalho4883 Жыл бұрын

    The best way to prevent PFS is not taking the drug unless you have a swollen prostate and urinary problems at the same time. Androgenetic alopecia is not a disease but a normal human condition.

  • @andrewvideos5328

    @andrewvideos5328

    Жыл бұрын

    How to cure?

  • @rickycarvalho4883

    @rickycarvalho4883

    Жыл бұрын

    @@andrewvideos5328 there's no cure for PFS, but there's treatment to reduce its symptoms!

  • @rickycarvalho4883

    @rickycarvalho4883

    8 ай бұрын

    @@tiagomoraes1510 balding doesn't kill anyone unless you have a mental problem.

  • @miguelalejandro4357

    @miguelalejandro4357

    6 ай бұрын

    I’m taking 5mg for prostate problems for 2 months .. I’m on day 35 of 60 and my libido is low and my erections are weak .. I wonder if the side effect Will Gone away after I ended my 2 months treatment?

  • @kauadasilva6140

    @kauadasilva6140

    4 ай бұрын

    wish i knew this before getting the sides tho, but yeah, lets keep going

  • @HairCofe
    @HairCofe2 ай бұрын

    finasteride, we can expect side effects to occur. For one, there’s increased GABA activity in the brain with DHT, likely due to DHT metabolites modulating GABA-A receptors (10, 11), which provides an anxiolytic effect (reduced anxiety). DHT may also modify circuitry in the brain by altering the number of excitatory spine synapses in a paracrine manner, which can therefore affect cognitive function (in a positive manner) of the brain (12). It’s been established that the risk of dementia is in fact greater for patients using 5α-reductase inhibitors (13), further demonstrating the need for DHT in the brain for adequate cognitive function and health. In male rats, it has been demonstrated that finasteride inhibits the brains dopaminergic system (involved in the reward system and sense of wellbeing) (14) which may well transfer to humans. It has even been suggested to use testosterone supplementation (note: within physiological levels) to improve cognition in older men, in part due to the neuroprotective and excitatory effects of DHT (12). Put simply, DHT is actually quite important for good mental health. It will reduce feelings of anxiety, improve feelings of wellbeing, and improve cognitive function. Additionally, progesterone (another important steroid hormone) can be converted to allopregnanolone via 5α-reductase. Allopregnanolone is a potent ligand of the GABA-A receptor, which in normal circumstances will reduce the risk of anxiety, major depression, impulsive aggression, and negative symptoms in schizophrenia (15). So, that’s another thing lost to the use of finasteride.

  • @icyrunner2070
    @icyrunner2070 Жыл бұрын

    What company is a good source to supplement pregnenalone from?

  • @husainismaeel2981
    @husainismaeel2981 Жыл бұрын

    Thanks for addressing the PFS topic. Can you make a video for PFS sufferers on how to recover? Thanks.

  • @fraooqkhan2293

    @fraooqkhan2293

    Жыл бұрын

    Bro r u the victim too?

  • @husainismaeel2981

    @husainismaeel2981

    Жыл бұрын

    @@fraooqkhan2293 yes for 2.5 yeats so far

  • @fraooqkhan2293

    @fraooqkhan2293

    Жыл бұрын

    @@husainismaeel2981 i am too scared to take it... losing hair in my 20s😔

  • @husainismaeel2981

    @husainismaeel2981

    Жыл бұрын

    @@fraooqkhan2293 Losing your hair is better than losing your health. If hair is your concern, there are safer alternatives out there. Finasteride has ruined my life.

  • @Vectorman2X

    @Vectorman2X

    Жыл бұрын

    @@husainismaeel2981 also mine, i am facing terrible health issues from 2005

  • @mikereynold2078
    @mikereynold2078 Жыл бұрын

    do you see a lot of success treating patients with post finasteride syndrome? it seems so hard to get back to our pre pfs state...

  • @HairCofe

    @HairCofe

    2 ай бұрын

    finasteride, we can expect side effects to occur. For one, there’s increased GABA activity in the brain with DHT, likely due to DHT metabolites modulating GABA-A receptors (10, 11), which provides an anxiolytic effect (reduced anxiety). DHT may also modify circuitry in the brain by altering the number of excitatory spine synapses in a paracrine manner, which can therefore affect cognitive function (in a positive manner) of the brain (12). It’s been established that the risk of dementia is in fact greater for patients using 5α-reductase inhibitors (13), further demonstrating the need for DHT in the brain for adequate cognitive function and health. In male rats, it has been demonstrated that finasteride inhibits the brains dopaminergic system (involved in the reward system and sense of wellbeing) (14) which may well transfer to humans. It has even been suggested to use testosterone supplementation (note: within physiological levels) to improve cognition in older men, in part due to the neuroprotective and excitatory effects of DHT (12). Put simply, DHT is actually quite important for good mental health. It will reduce feelings of anxiety, improve feelings of wellbeing, and improve cognitive function. Additionally, progesterone (another important steroid hormone) can be converted to allopregnanolone via 5α-reductase. Allopregnanolone is a potent ligand of the GABA-A receptor, which in normal circumstances will reduce the risk of anxiety, major depression, impulsive aggression, and negative symptoms in schizophrenia (15). So, that’s another thing lost to the use of finasteride.finasteride, we can expect side effects to occur. For one, there’s increased GABA activity in the brain with DHT, likely due to DHT metabolites modulating GABA-A receptors (10, 11), which provides an anxiolytic effect (reduced anxiety). DHT may also modify circuitry in the brain by altering the number of excitatory spine synapses in a paracrine manner, which can therefore affect cognitive function (in a positive manner) of the brain (12). It’s been established that the risk of dementia is in fact greater for patients using 5α-reductase inhibitors (13), further demonstrating the need for DHT in the brain for adequate cognitive function and health. In male rats, it has been demonstrated that finasteride inhibits the brains dopaminergic system (involved in the reward system and sense of wellbeing) (14) which may well transfer to humans. It has even been suggested to use testosterone supplementation (note: within physiological levels) to improve cognition in older men, in part due to the neuroprotective and excitatory effects of DHT (12). Put simply, DHT is actually quite important for good mental health. It will reduce feelings of anxiety, improve feelings of wellbeing, and improve cognitive function. Additionally, progesterone (another important steroid hormone) can be converted to allopregnanolone via 5α-reductase. Allopregnanolone is a potent ligand of the GABA-A receptor, which in normal circumstances will reduce the risk of anxiety, major depression, impulsive aggression, and negative symptoms in schizophrenia (15). So, that’s another thing lost to the use of finasteride.

  • @Man-u-flex
    @Man-u-flex Жыл бұрын

    I heard testing interleuken 8 will tell you if you have pfs because of the neuro cns inflammation.

  • @tired_of_everything0

    @tired_of_everything0

    10 ай бұрын

    how are you now. did you have it

  • @Vectorman2X
    @Vectorman2X Жыл бұрын

    My next supplement to try is PEA (Palmitoylethanolamide) this supplement supposed to restore the function of the star protein. Steroid regulatory protein. Its the protein that is responsible for neurosteroid genesis in our brain, many exams reveal that fina downregulate star protein and this is one of the major problems that is associated with pfs.I read that hcg upregulate star protein, but pea is a more safe route.

  • @shawnpeters2196

    @shawnpeters2196

    Жыл бұрын

    Did it work??

  • @rustysack2568

    @rustysack2568

    2 ай бұрын

    Why even comment if you aren’t going to give an update?

  • @Vectorman2X

    @Vectorman2X

    2 ай бұрын

    @@shawnpeters2196 Sorry for the late reply, pea dont work for me. I can testify that tribulus terestris work, i am on this 2 g per day and i feel a lot better, the problem is that when i stopping it the results diminished.

  • @Vectorman2X

    @Vectorman2X

    2 ай бұрын

    @@rustysack2568 Sorry for the late reply, pea dont work for me. I can testify that tribulus terestris work, i am on this 2 g per day and i feel a lot better, the problem is that when i stopping it the results diminished.

  • @miguelalejandro4357
    @miguelalejandro43576 ай бұрын

    I’m taking 5mg for prostate problems for 2 months .. I’m on day 35 of 60 and my libido is low and my erections are weak .. I wonder if the side effect Will Gone away after I ended my 2 months treatment?

  • @pitbullsami8475

    @pitbullsami8475

    4 ай бұрын

    Update ?

  • @miguelalejandro4357

    @miguelalejandro4357

    4 ай бұрын

    @@pitbullsami8475 after a few days of leaving finasteride 5mg my libido went back to normal !!

  • @Yiahi65
    @Yiahi65 Жыл бұрын

    Hey guys the pfs community has two huge studies going on and we need more backing to have more studies, the faster we get the studies done the faster we will get to a cure. Hit me up let’s make this bullshit something of the past. We’re confident we can fix this. Donate anything helps. Lmk

  • @IgrwOw
    @IgrwOw Жыл бұрын

    My androgens were at the sky. It didn't prevent me from drowning in this hell of Post finasteride syndrome. 14 days of topical! 6 months of mental and sexual side effects..

  • @tired_of_everything0

    @tired_of_everything0

    10 ай бұрын

    what are the mental effects

  • @IgrwOw

    @IgrwOw

    10 ай бұрын

    @@tired_of_everything0 brain fog, personality is gone, no good feelings. Difficulty concentrating and poor memory..

  • @tired_of_everything0

    @tired_of_everything0

    10 ай бұрын

    @@IgrwOw I can't even taste or smell food. The anhedonia is also severe

  • @kxni122

    @kxni122

    5 ай бұрын

    this is not possible with finasteride dont taske or smell food ? cmon man stop self diagnose no study shows these symptoms@@tired_of_everything0

  • @kauadasilva6140

    @kauadasilva6140

    4 ай бұрын

    yes, its rather unpredictable how it can affect people, as most say, its like a russian roulette unfortunately