How to Draw Haworth Projections of L and D Glucose from Fischer Projections | Chemistry Tutorial
In this video, we will go through how to draw Haworth projections of both L and Glucose from a Fischer Projection. I will go through a step by step process of how to number your carbons, determine your ring size, draw your OH groups for your projections.
I will also discuss alpha and beta anomers and how you know which version you will have in most introductory biochemistry courses and problems. Alpha and Beta anomers exist in a state of equilibrium due to the monosaccharide ring being able to open and close. Meaning that both alpha and beta exist naturally within the cell and the body. We will also briefly discuss the concept of mutarotation as well.
0:00 Introduction to Carbohydrates
0:36 Step 1: Draw the Enantiomer of your Fischer Projection
2:52 Step 2: Rotation Structure Clockwise 90 degrees for Top/Bottom
4:34 Step 3: Determine Ring Size (5 or 6 Carbons)
7:27 Step 4: Build your projection, place top and bottom, and CH2OH (L or D)
12:21 Step 5: Alpha or Beta? Anomers Explained!
14:38 Final Haworth Projections labeled and shown
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Want to Learn More on this Topic: Learn to Draw a Fischer Projection Starting from a Haworth (Backwards): kzread.info/dash/bejne/mHaK2o-ij6jOncY.html Cyclic Acetals and Ketals: Step by Step Reaction: kzread.info/dash/bejne/qZyKrsyKmNuZdqw.html
Thank you very much. I really appreciated the video, because it helped me to understand beta and alpha Haworth projections.
@ItsDrDan
Ай бұрын
You are absolutely welcome :) I am so happy that it helped you. I wish I was able to put these out faster for all of you students :)
You are the best wow it's been so helpful indeed
@ItsDrDan
11 күн бұрын
I'm so glad that it was helpful!
This was super helpful
@ItsDrDan
15 күн бұрын
Glad you think so!
Really helpful thank you ❤
Thank you for your Video! You’re very good at explaining! 😊 My question would be: how do you figure out alpha and beta with pentapyranoses like alpha-L-Arabinose since it doesn’t have the CH2OH group?
@ItsDrDan
4 ай бұрын
Thank you so much! Those ones are a little strange being that they can become the 5 ring or 6 ring structure. I know that alpha and beta are still based on if the OH group is written down or up. L or D would be based off the original Fischer projection or chirality of the molecule. I may be incorrect, but i believe the 5 member ring isomerizes into the 6 member ring. The labeling is based off what the 5 member ring would have been for a molecule like arabinose… so if the 5 member furanose structure was alpha-L then the pyramids structure would also be alpha-L even though it does not have the CH2OH group. As long as you draw the Haworth projection. I would say the alpha or beta notation would be based off how the OH is pointed, which both of them would be possible to exist.
@anjac8131
4 ай бұрын
Thank you so much for your detailed answer! I will totally look more into what you described! All the best from germany 😊
@ItsDrDan
4 ай бұрын
@@anjac8131 You are very welcome! Hopefully, it was able to help a little bit. Best of luck with your studies!