How mRNA helped save lives: DNA Transcription: Crash Course Biology #34

You’ve probably heard of mRNA, thanks to the COVID-19 vaccine. But what is mRNA exactly? In this episode of Crash Course Biology, we learn about the role of messenger RNA in living things and how it decodes our DNA instruction manual through transcription.
Introduction: mRNA Vaccines 00:00
Messenger RNA 1:21
Transcription 3:48
Processing & Splicing 5:05
The Central Dogma 7:00
Alternative Splicing 8:39
Review & Credits 10:46
This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.
Check out our Biology playlist here: • Biology
Watch this series in Spanish on our Crash Course en Español channel here: • Crash Course Biología
Sources: docs.google.com/document/d/1G...
***
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Пікірлер: 41

  • @sebali-ferguson6303
    @sebali-ferguson63032 ай бұрын

    CrashCourse BIOCHEMISTRY WHEN?

  • @romanatorx3949
    @romanatorx39492 ай бұрын

    Yay! As a bioinformatician working with a lot ofnRNA data I can send this video to my students.

  • @trevinbeattie4888
    @trevinbeattie48882 ай бұрын

    It’s amazing to me that biologists have learned how DNA/RNA works well enough that we can now splice genes and manufacture mRNA fragments so we can treat a number of diseases and disorders this way.

  • @adpirtle
    @adpirtle2 ай бұрын

    The molecular machines that operate away in our cells are so fascinating.

  • @mattkuhn6634
    @mattkuhn66342 ай бұрын

    Dr Sammy continues to be amazing - that "devour a good book" line had such excellent delivery it had me laughing for minutes!

  • @Iceberg_maal
    @Iceberg_maal2 ай бұрын

    Oh I can't wait to read these comments 😂😂😂

  • @adamphilip1623
    @adamphilip16232 ай бұрын

    Loving this series, really informative, fun and engaging and that's coming from someone who has always struggled to really engage with cellular biology in particular. Also I love the host choice, Dr Sammy is great!

  • @AjayKumaR-vd1gy
    @AjayKumaR-vd1gy2 ай бұрын

    💯 my research interest topic 😀

  • @gregmiller9710
    @gregmiller97102 ай бұрын

    i was totally unaware of how the covid flu shot worked...now i might get one because i haven't yet due to allergic reaction to the shingles vaccine.....thanks for the education ! :)

  • @pinktights747
    @pinktights7472 ай бұрын

    Thank you for the free education. I payed a small fortune at the University.❤❤❤😂😂

  • @adamphilip1623
    @adamphilip16232 ай бұрын

    Really good coverage of the covid vaccine for this context!

  • @Teo117
    @Teo1172 ай бұрын

    Phenomenal description!

  • @gailaltschwager7377
    @gailaltschwager73772 ай бұрын

    Thank you!

  • @ich3aa
    @ich3aa2 ай бұрын

    Hey, good video

  • @sweetcreemaker
    @sweetcreemaker2 ай бұрын

    I love science ❤

  • @bvillafuerte765
    @bvillafuerte7652 ай бұрын

    Good video.

  • @turtler3603
    @turtler36032 ай бұрын

    i'm too early for the translation video when my test is in a few days :( unfortunate but this video was still helpful :)

  • @andrewp6738
    @andrewp67382 ай бұрын

    Hell yeah

  • @starc.
    @starc.2 ай бұрын

    fantastic video can you follow it up with more?

  • @nebulan
    @nebulanАй бұрын

    8:41 what science is about

  • @jawaharkonathala6950
    @jawaharkonathala69502 ай бұрын

    Can you please give examples which help students from other countries also to understand? Like I didn't understand the platypus playground.

  • @culwin

    @culwin

    2 ай бұрын

    Platypusses aren't native to America, and I can still understand just fine. If you still don't know what a platypus is, you can use a popular search engine such as Google to find out about them. I don't think it is necessary to understand anything about the video, though.

  • @beo_freo
    @beo_freo2 ай бұрын

    Unrelated question, but are those jellyfish in the background real? :c

  • @Clownworld37
    @Clownworld372 ай бұрын

    My heart!

  • @pcxPOT

    @pcxPOT

    2 ай бұрын

    myocarditis?

  • @wissam_fares
    @wissam_fares2 ай бұрын

    👍🏼👍🏼

  • @Nick-zp8wk
    @Nick-zp8wk2 ай бұрын

    So uhhh, why did Hank stop hosting again? 🌝

  • @floatingleaf9672
    @floatingleaf96722 ай бұрын

    It is important to add any risks involved in such a crash course; IMHO it is irresponsible not to. Please research off-target effects. Any potential risks involved should also be mentioned so that we can be informed. Or maybe there are no risks? But that is unlikely and certainly long term unknown. Thank You!!

  • @gqsnowman

    @gqsnowman

    2 ай бұрын

    But this is about the technology and how it works. The potential risks of treatment will differ wildly depending on what application it's used for, how it's delivered, and a ton of other factors. What you're asking for is like asking for every potential bad thing that might happen on facebook on a video about how the internet works.

  • @raidwipe

    @raidwipe

    2 ай бұрын

    have you seen the list of risks when taking ibuprofen?

  • @epiren

    @epiren

    2 ай бұрын

    Hi, epidemiologist here and editor of History of Vaccines. All vaccines come with risks, but none of the "off-target" effects bandied about by anti-vaccine organizations and activists. The mRNA from the vaccine never touches our DNA, and it has a very hard time even getting inside the nucleus. As for long-term effects, with billions vaccinated in the last three years, we have millions of life-years of analysis. It's funny, because the same was said of the smallpox vaccine in the late 1700s and early 1800s. "It's going to turn you into a cow!" Then again with the rabies vaccine in the late 1800s. "It's going to make you act like a rabid dog!" And then again with polio. "It will paralyze you!" Every vaccine has brought its own misguided misinformation, while the actual side effects were far and few in between... And certainly much rarer than the effects of the diseases themselves. And when there were issues, the vaccines were quickly taken off the market. So, yeah, no "turbo cancer" (which is a great name for a metal band), no "died suddenly" (which should be the name of a computer brand), and no "off target" effects.

  • @ErebosGR

    @ErebosGR

    2 ай бұрын

    Ask your doctor, troll.

  • @punki2291

    @punki2291

    2 ай бұрын

    Risk about what? mRNA Covid vaccine? You get the risk sheet everytime when you go get the shot. It's safe and work as intended. It's the conclusion of a Cochrane review, it settle the scientific consensus. Really low chance of long term effect since it's not a drugs taken each day. It's impossible to cause more long term effect then what the covid-19 already does since the virus is more then the spike protein mRNA that it already contain. I talking as a Microbiology student

  • @mashrabjonqoldoshev2599
    @mashrabjonqoldoshev25992 ай бұрын

    1

  • @user-kh2fs2sv5y
    @user-kh2fs2sv5y2 ай бұрын

    As king David under inspiration said we are wonderfully made.. praise God Almighty

  • @Denise-ux4xd
    @Denise-ux4xd2 ай бұрын

    BI🛑WEAP🛑N

  • @an740ny
    @an740ny2 ай бұрын

    "helped save lives" 😅 🤨

  • @Noobahmastah
    @Noobahmastah2 ай бұрын

    This and HurkaDurrGesagt are transparently prop-up-ganduhrr at this point.