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Sir thank you so much, I love the way you teach pathology, please don't stop releasing videos...

I like the way you simply explain the hard concept. We also need alot video sir thanks alot 🙏🙏

Thanks a lot doctor Plz is there any video for non~hodgkin

Sir Please make video on MI

@ilovepathologyVijayPatho

25 күн бұрын

Sure

So sir, RS cells are the one that are considered neoplastic within the lymph node affected, even though the entire bulk is coming from the reactive surrounding lymphoid cells (depending on the subtype involved). So my query here, first is the aforementioned statement correct? And second, what's so neoplastic about RS cells, meaning, do they have the ability of replication as like any other cancer? (Do RS cell give rise to another RS cell or they are permanently differentiated?) And does the surrounding B cells are expected to transform into RS cells also?

@ilovepathologyVijayPatho

27 күн бұрын

Yeah.. The first statement is correct RS are derived from germinal center B cells and are the terminally differentiated ones.. So. They don't divide.. And at the same time, they escape death too.. The mechanisms I have explained in pathogenesis.. Not all B cells can give rise to RS cells... Its only from the ones in germinal Centre

@waelfadlallah8939

27 күн бұрын

@@ilovepathologyVijayPatho thank you for the comprehensive explanation 🙏