Heme Synthesis Pathway (and Associated Diseases)

​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

Пікірлер: 127

  • @DirtyMedicine
    @DirtyMedicine3 жыл бұрын

    Correction: Sulfonamides are P450 INHIBITORS however Sulfonamide antibiotics are still contraindicated

  • @partofaheart
    @partofaheart3 жыл бұрын

    I use AminoLEAVEulinic acid (leaves the mitochondria).

  • @motivationtostrive1216

    @motivationtostrive1216

    2 жыл бұрын

    Ohhjjj!!!!! That's smart 😉

  • @abdelrahmanmahmoud2527

    @abdelrahmanmahmoud2527

    2 жыл бұрын

    I like it 😁😁

  • @aradhanakkannan5450

    @aradhanakkannan5450

    Жыл бұрын

    Interesting.. tnx doc..!!

  • @ahmedfareed6546

    @ahmedfareed6546

    6 ай бұрын

    & Copro=Come back 😁

  • @Dilheimer11

    @Dilheimer11

    5 ай бұрын

    Fire.

  • @faisalal-tamimi4683
    @faisalal-tamimi46832 жыл бұрын

    Dude, you saved me from failing the part of heme synthesis, gigantic thanks to you.

  • @BooksOverKindle
    @BooksOverKindle6 ай бұрын

    You're a terrific teacher, hands down the best one to convert the burden of memorizing biochemistry cycles into a cakewalk.

  • @BooksOverKindle

    @BooksOverKindle

    6 ай бұрын

    Thankyou so much for all your efforts Sir🙌

  • @haganlawson8332
    @haganlawson83322 жыл бұрын

    I have so many resource available to me -- this is by far the best video I have seen covering this topic! Really great job here!

  • @ave8197
    @ave81973 жыл бұрын

    I wish I'd seen this this morning right before my practice test with like 5 questions on this topic *cries* seriously it's like you know exactly what I struggle with and make videos on it thank you soooo much

  • @fabehaali9013
    @fabehaali90132 жыл бұрын

    Tysm! U r an amazing teacher. Your mnemonics actually make sense and the way u teach is just amazing!! Please keep making more videos!!

  • @user-zz4qs7uz3q
    @user-zz4qs7uz3q Жыл бұрын

    Your video is AWESOME! Thank you so much. You have no idea how excellent this was!

  • @zak99msu
    @zak99msu9 ай бұрын

    Thanks you for providing such an amazing resource and making it available for medical students without cost!!!

  • @rueloka
    @rueloka3 жыл бұрын

    YESSSS!!!! 🙏🏾🙏🏾🙏🏾 test in 5 days

  • @priyam1550

    @priyam1550

    3 жыл бұрын

    Good luck! Mine is in 10!

  • @rueloka

    @rueloka

    3 жыл бұрын

    Good luck guys 🥺🥺🥺🥺 y’all got it!

  • @siphiwechanza1420

    @siphiwechanza1420

    2 жыл бұрын

    Test in the next 8 hours 😭🕯️

  • @Be1smaht

    @Be1smaht

    2 жыл бұрын

    3 day!

  • @siphiwechanza1420

    @siphiwechanza1420

    2 жыл бұрын

    @@Be1smaht All the best God bless

  • @oconnor5628
    @oconnor56282 жыл бұрын

    For lead signs, I think "A Basic Stapler vs a Lead Pipe"... Lead pipes are linear so you get the burton lines and lead lines on bones. Additionaly, Basic Stapler for the basic stippling. Stapler holes in papers once they are removed look kind of granular . Just my memory hook.

  • @robertocordero9742
    @robertocordero97423 жыл бұрын

    KING!! its the ✨mnemonics✨ for me 💕

  • @disneygirl19714
    @disneygirl197143 жыл бұрын

    iconic, yet again. my mans don't miss.

  • @mesiloa
    @mesiloa2 жыл бұрын

    I am going to support your channel, it has been helpful to summarize a lot of Biochemistry which is very confusing.

  • @annad6619
    @annad66192 жыл бұрын

    great as always 😍👏🏻 Also for Lead, I use: ALA (girl) & Ferro (boy) played with lead 😄

  • @gyang17
    @gyang177 күн бұрын

    You're the best! This was extremely helpful!

  • @betinahnamaganda1805
    @betinahnamaganda18052 жыл бұрын

    U are extremely good. Thank you so much Sir! U have simplified my life

  • @user-fc9tn1sk4j
    @user-fc9tn1sk4j Жыл бұрын

    Dirty! I love you! Porphyrias always were my problem until this video! Thank you so much!

  • @komaldiptianandmaisuriya4301
    @komaldiptianandmaisuriya43017 ай бұрын

    Your biochem , pharma ,patho video really really helped me pass step 1 .so grateful.god bless.really beyond. great work doc.

  • @muzamara

    @muzamara

    5 ай бұрын

    Congrats!! Is the real deal similar to UWORLD or the NBMEs?

  • @udennaebii1585
    @udennaebii15852 жыл бұрын

    I'm so grateful. Thank you

  • @ewertonuchoaMD
    @ewertonuchoaMD3 жыл бұрын

    I think the Heme Synthesis Mnemo was the best until now :D. Awesome Video as always.

  • @mbbslife3780

    @mbbslife3780

    3 жыл бұрын

    Loved this video on heme synthesis ❤️❤️😘

  • @mennaayman2972
    @mennaayman29722 жыл бұрын

    thank you so much for your dedication

  • @KASH.ISH16
    @KASH.ISH16 Жыл бұрын

    I just want to say thank you and u r a great teacher toooo 🎉 congratulations

  • @acepokemontrainer1
    @acepokemontrainer12 жыл бұрын

    Thanks for another great video!

  • @khulooda4921
    @khulooda4921 Жыл бұрын

    Bro I’m thankful for you forever

  • @priyam1550
    @priyam15503 жыл бұрын

    Thank you! Just in time for my exam!

  • @ja4615
    @ja46159 ай бұрын

    This video is very helpful! Thank you!

  • @drcaocuong
    @drcaocuong5 ай бұрын

    you saved me from biochemistry. Thanks to you !

  • @aradhanakkannan5450
    @aradhanakkannan5450 Жыл бұрын

    Easily registered... thank u doc!

  • @anjumiqbal1676
    @anjumiqbal16762 жыл бұрын

    Very informative and easy to understand video

  • @padmajahawaldar4319
    @padmajahawaldar43195 ай бұрын

    God of teaching medicine ❤

  • @Krishna-ub6ij
    @Krishna-ub6ij3 жыл бұрын

    Thank you so much . This topic is extremely volatile for me and you made it easy.

  • @somalarif6474
    @somalarif64743 жыл бұрын

    thanks for the vedio Your lecture helped me to make my assignment

  • @KinzaHussain
    @KinzaHussain3 жыл бұрын

    Thank you xx

  • @prashanth-py9jc
    @prashanth-py9jc3 жыл бұрын

    Superb I learn more from you thank you

  • @AbubakarUmarMusa
    @AbubakarUmarMusa2 жыл бұрын

    Great Lectures

  • @levi--ackerman
    @levi--ackerman Жыл бұрын

    WHY ON EARTH IS HE SO UNDERRATED?!

  • @dr-bg8tn
    @dr-bg8tn2 жыл бұрын

    amazing thanks dr , is there a vid for lymphoma ?

  • @jacybaxter5457
    @jacybaxter54572 жыл бұрын

    thank you! super helpful video

  • @robindcole
    @robindcole2 жыл бұрын

    You are a good person.

  • @agarwalshivam844
    @agarwalshivam8443 жыл бұрын

    Amazing video! Is there an easy way to learn the anatomy of the respiratory tree (like where we find goblet cells, cartilage, club cells, pseudo-stratified epithelium, smooth muscles, cilia etc)?

  • @mahekrai8915

    @mahekrai8915

    2 жыл бұрын

    If you find this, please tell 🥺

  • @DrRomaMD

    @DrRomaMD

    Жыл бұрын

    Cartilage till bronchi start of club cells in bronchioles Cilia last to disappear till respiratory bronchioles start from the travhra

  • @hakaromer
    @hakaromer2 жыл бұрын

    الله على أخلاقك يا فخر اليوتوب

  • @RyanBintangSatria
    @RyanBintangSatria Жыл бұрын

    Definitely worth to subscribe

  • @ZhivagoDoctor
    @ZhivagoDoctor2 жыл бұрын

    Amazing video !!!

  • @noellestarr5158
    @noellestarr5158Ай бұрын

    Absolute banger mnemonic

  • @KSJ1290
    @KSJ1290 Жыл бұрын

    Clear cut lecture, ty!

  • @HazratAli-oz9ty
    @HazratAli-oz9ty2 ай бұрын

    love the way you teach sir🥰

  • @CP-ov8sd
    @CP-ov8sd Жыл бұрын

    another way to remember which steps occur in the mitochondria: just remember the FIRST and LAST step are the ONLY ones to occur in the mitochondria (if you dont wanna remember his mnemonic and this conceptually makes sense to you)

  • @meenabarot2037
    @meenabarot2037 Жыл бұрын

    Wow!! Fantastic

  • @tawfeekb24
    @tawfeekb24 Жыл бұрын

    Dirty, you and all who make similar videos deserve a special spot in heaven.

  • @ThienTruong-iy5ix
    @ThienTruong-iy5ix4 ай бұрын

    a mnemonic for the Heme synthesis pathway if you prefer an alternative Great Scholars Always Prioritize Higher Understanding, Creating Profound HEMEpothesis(hypothesis) Cheers,

  • @tasneem5412
    @tasneem54123 жыл бұрын

    Chef’s kiss 🤌🏻😘

  • @cristinalee5174
    @cristinalee51742 жыл бұрын

    For the pathway mnewmonic "for" can be where Fe+2 enters the pathway

  • @aremuoreoluwa3649
    @aremuoreoluwa3649 Жыл бұрын

    Thank you🥺🥺

  • @maymayansay
    @maymayansay3 жыл бұрын

    Hahaha when he said BOOM! right after the mnemonic, went ROFL coz the mnemonic's REALLYYYY amazing!!!!!!!

  • @eugeniaagnesrombelayuk1789
    @eugeniaagnesrombelayuk1789 Жыл бұрын

    you are a life-saver :')

  • @AngelaHairston1
    @AngelaHairston1 Жыл бұрын

    Love you too! Thanks.

  • @xaaboopinkly
    @xaaboopinkly3 жыл бұрын

    Thanks sir!

  • @mishuhashem8642
    @mishuhashem8642 Жыл бұрын

    Amazing video

  • @asisababun7543
    @asisababun75439 ай бұрын

    Thanks!

  • @johnshrestha5767
    @johnshrestha57672 жыл бұрын

    You are the best

  • @alijafari25
    @alijafari256 ай бұрын

    And that's why he's GOAT, the GOAT 🐐🐐🐐

  • @emilioaguinaldo7101
    @emilioaguinaldo71013 жыл бұрын

    nice summary

  • @otmanezogdani
    @otmanezogdani11 ай бұрын

    Hey, thank you for these valuable videos, can you please provide us with the PDF

  • @kisemilekatepa3842
    @kisemilekatepa38422 жыл бұрын

    Thanks Much broo!

  • @heyitstoast8693
    @heyitstoast86938 ай бұрын

    I have porphyria, I have a cellular test showing I’m completely deficient in b6, also serine so I’m assuming I could be low in glycine as well. I might have a gene where I can’t covert pyridoxine into Pyridoxal 5 phosphate. I was experiencing severe attacks, hospital couldn’t figure out what was wrong with me. I ordered the active b6 and got immediately better each day. I’m working with a functional dr who found my porphyrians are extremely high. We are still trying to rule out of anything else could be causing this but I’m hoping it’s just b6 deficiency. I can’t drink alcohol either ever. I turn white and need to recover for days after

  • @zainabhatem85
    @zainabhatem852 жыл бұрын

    Perfect !

  • @fedhasahisa5282

    @fedhasahisa5282

    Жыл бұрын

    PERFECT

  • @elizabethphiri6740
    @elizabethphiri674011 ай бұрын

    Really useful

  • @benwolde3881
    @benwolde3881 Жыл бұрын

    wow, i can not thank you enough.

  • @cjfree8813
    @cjfree88133 жыл бұрын

    bro...

  • @ToothTalksHub
    @ToothTalksHub3 жыл бұрын

    Why are you so awesome?🔥🔥

  • @sravyareadyy
    @sravyareadyy2 жыл бұрын

    how does hydroxychloroquine help in PCT?

  • @georgeiribar8412
    @georgeiribar8412 Жыл бұрын

    If lead inhibited ALA dehydratase , the pathway should stop here right? So, how come it continues to protoporphyrin 9?

  • @davidrios1492
    @davidrios14925 ай бұрын

    i love you man

  • @ajabisong
    @ajabisong4 ай бұрын

    Aminolev LEAVES, COP enters.

  • @redpilledbachelor7776
    @redpilledbachelor77763 жыл бұрын

    I should study for my nursing final, but nah, I'm watching this first. The test contains anemia and hematology too.

  • @lanaakhras4909
    @lanaakhras49093 жыл бұрын

    Omggggggg ur the best !!!!!

  • @bookbites101quotes
    @bookbites101quotes3 жыл бұрын

    Congenital erythropoietic porphyria ?

  • @user-mg8tc5ko7q
    @user-mg8tc5ko7q10 ай бұрын

    Where can I download your lectures?

  • @rafisarhandi5626
    @rafisarhandi5626Ай бұрын

    For Lead , use ALEAD instead of ALAD (both pronounced as A lead)

  • @sassydancers3601
    @sassydancers3601 Жыл бұрын

    Can you please make a video on gene mutations!!

  • @ashutoshanand8831
    @ashutoshanand88313 жыл бұрын

    You are the best .

  • @rameezakhan985
    @rameezakhan985 Жыл бұрын

    Thankk uuuu❤❤❤❤❤

  • @yukizrox
    @yukizrox3 жыл бұрын

    For the slide on sideroblastic anemia, the HY point seems to be incorrectly presented. Should it be isoniazid consumption --> B6 def? Instead of isoniazid deficiency?

  • @DirtyMedicine

    @DirtyMedicine

    3 жыл бұрын

    I meant to type Isoniazid Induced Deficiency > B6 Deficiency. I left out the word "induced" but if you listen to the words I say you still get to the same end point

  • @tenawobebetwo3917
    @tenawobebetwo39175 ай бұрын

    Please someone explain to me. I am confused with the pathogenesis of lead poisoning. Is it lead poisoning that inhibits those enzymes or does the deficiency of those enzymes lead to lead poisoning? I believe the former is.

  • @Thegoodchanelsonly
    @Thegoodchanelsonly2 ай бұрын

    5:10 The first and Last step in Mitochondria

  • @chiahsuantsauo8375
    @chiahsuantsauo83752 жыл бұрын

    Wait so erythropoietic protoporphyria, coproporphyria, and variegate porphyria isn't important?

  • @augustortiz
    @augustortiz Жыл бұрын

    7:38 That pneumonic should qualify you for a Noble Prize.

  • @foodiesworldUSA
    @foodiesworldUSA Жыл бұрын

    How does lead poisoning cause sideroblastic anemia

  • @rickydhouse18
    @rickydhouse18 Жыл бұрын

    Just in case you need to remember when Iron comes into this process. Same mnemonic, "Get Some Additional..." but change the end "for Heme" to "(Fe)r Heme". Good luck fam.

  • @maabhussein9910
    @maabhussein99102 жыл бұрын

    ♥️♥️♥️

  • @sirikadenu5462
    @sirikadenu54624 ай бұрын

  • @fatemaabdulla2728
    @fatemaabdulla2728 Жыл бұрын

    the mnemonics had me cracking

  • @Thegoodchanelsonly
    @Thegoodchanelsonly2 ай бұрын

    FEAD LEAD , FE ferrocheltase AD ala dehydretase

  • @shaynemcgowan4049
    @shaynemcgowan40493 жыл бұрын

    Amino-leave-ulinic acid 🤔

  • @cacayanhilarynicole3620
    @cacayanhilarynicole362010 ай бұрын

    If only I had watched your video last year, I wouldn't have failed hematology 1

  • @jamiek6471
    @jamiek64713 жыл бұрын

    i love you

  • @burteenkhbold6297
    @burteenkhbold6297 Жыл бұрын

    love you Dirty

  • @hritvikjain__3594
    @hritvikjain__35942 жыл бұрын

    good shit dirty!

  • @lyly-wc1rj
    @lyly-wc1rj2 жыл бұрын

    مو دكتور ضيم مع تحياتي لبقية الدكاتره خليعزلون ويفتحون چمبر مخضر 😂