Genomics Has a Diversity Problem

Someday, the information in our genome could transform healthcare as we know it, but one major hurdle we have to get over is the lack of diversity in our studies.
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#genomics #science #research #STEM
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Sources:
ghr.nlm.nih.gov/primer/precis...
www.yalemedicine.org/stories/...
ghr.nlm.nih.gov/primer/precis...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/books/NB...
journals.plos.org/plosmedicin...
www.ucsf.edu/news/2015/12/401...
www.healthaffairs.org/doi/abs...
www.cdc.gov/tuskegee/timeline...
www.cdc.gov/minorityhealth/CH...
www.kff.org/disparities-polic...
www.nap.edu/read/24624/chapter/5
www.genome.gov/about-genomics...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.sciencedaily.com/releases...
www.ncbi.nlm.nih.gov/grc/human
www.nature.com/articles/s4158...
www.ncbi.nlm.nih.gov/books/NB...
www.ncbi.nlm.nih.gov/pmc/arti...
www.nejm.org/doi/full/10.1056...
www.technologyreview.com/s/61...
www.ucsf.edu/news/2016/05/402...
www.ncbi.nlm.nih.gov/pmc/arti...
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www.ashg.org/press/201904-hgsi...
www.ncbi.nlm.nih.gov/pmc/arti...

Пікірлер: 1 600

  • @SciShow
    @SciShow5 жыл бұрын

    Skillshare is offering SciShow viewers two months of unlimited access to Skillshare for free! Try it here: skl.sh/scishow-15

  • @TheNeoLoneWolf

    @TheNeoLoneWolf

    5 жыл бұрын

    0:56 Ya, we need to focus more research on those blue people!

  • @jaredchappell2318

    @jaredchappell2318

    5 жыл бұрын

    💩💩💩

  • @VariantAEC

    @VariantAEC

    5 жыл бұрын

    So you're telling me the fact that I'm not white might potentially be fu••ing with doctors ability to correctly diagnose me??? *TELL ME SOMETHING I DON'T KNOW!*

  • @sunnymon1436

    @sunnymon1436

    5 жыл бұрын

    Hey @SciShow - "white people" aren't really a thing.... like... albino africans exist (but you're not talking about them when you say "white people" - even though they're people who are white)... whole villages in India and the Caucasus region look like white people but have very different genetic characteristics. If you're going to be a science show - be a science show - and don't get bogged down in this fallacious common language... or these unhealthy ideas. Western Europeans are a thing... white people... er.... not so much.

  • @Skylancer727

    @Skylancer727

    5 жыл бұрын

    @@TheNeoLoneWolf Believe it or not, there is actually a story of blue people existing, but they were actually just a mutant form of European. Basically it was found that their blood failed to carry the proper amount of oxygen making their skin turn blue. A doctor later devised a shot which seemed to cure the disease. It's one of those odd stories in Mysteries at the Museum. Gotta love weird history. owlcation.com/humanities/Blue-People-in-Kentucky-A-True-Story-of-a-Family-with-Blue-Skin

  • @General12th
    @General12th5 жыл бұрын

    I don't understand why this is controversial. We need more data. We don't have that data. Therefore, we should try to get more data. Simple as that.

  • @printedwit

    @printedwit

    5 жыл бұрын

    this needs to be pinned to this video. the comment section is a cluster.

  • @emperortgp2424

    @emperortgp2424

    5 жыл бұрын

    @@DK-td2sh When was that said in the video?

  • @leobat7007

    @leobat7007

    5 жыл бұрын

    J.J. Shank It's controversiam because there is no "we". Some people needs more diverse data, some others don't. And those who don't are the ones who are apparently supposed to pay for it.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    Because reactionarys and conservative like feelings over facts so they feel as if discrimination isn't a thing so they refuse to swallow that truth.

  • @EeliyaRasta

    @EeliyaRasta

    5 жыл бұрын

    My dentist happens to be a black person. Once I told him that I did 23andme and he told me that you shouldn't have given your DNA to the government. It's not my fault that he thinks like that. I would be more than happy that he participate :) but I think that won't happen :(

  • @Sciencerely
    @Sciencerely5 жыл бұрын

    As a stem cell researcher, I can tell you that people indeed sometimes react differently to certain drugs. 6-mercaptopurine for instance is a very effective drug to treat children who suffer from leukemia. However, if a child has a certain gene variation in NUDT15 this drug becomes toxic and life-threatening (the frequency of this gene variation varies between different ethnic groups). Analyzing this gene in children before giving them 6-mercaptopurine therefore is very important (but commonly not done)! Although I have a small KZread channel, I'm planning to make a video about this topic to spread awareness!

  • @TitanUranusOfficial

    @TitanUranusOfficial

    5 жыл бұрын

    Your channel is now one subscriber bigger.

  • @Gaaraape

    @Gaaraape

    5 жыл бұрын

    @SoftserveSodium who's shaming who?

  • @10feralratsinacoat76

    @10feralratsinacoat76

    5 жыл бұрын

    Your channel looks interesting and I plan on watching your cancer vaccine video. You also make a really interesting point that I’ve never really thought about. I hope you make that video :)

  • @shadmanigat2232

    @shadmanigat2232

    5 жыл бұрын

    Your smart

  • @zes7215

    @zes7215

    5 жыл бұрын

    wrr

  • @lucas29476
    @lucas294765 жыл бұрын

    Hey, really crucial recommendation here: number your sources in your video and description. Like so they can see this please. This is supposed to be the norm for educational channels. Thanks.

  • @PeppoMusic

    @PeppoMusic

    5 жыл бұрын

    While that would be quite a bit more work, that would indeed be much better! That way you can check specific statements, without having to go through all the sources.

  • @IzzyIkigai

    @IzzyIkigai

    5 жыл бұрын

    Not just educational channels, literally any channel working with sources. Like.. If that German musician tearing apart the biggest german political party can do it in an hour long video just by himself, a channel like SciShow should be easily able to do this as well...

  • @Maxfr8

    @Maxfr8

    5 жыл бұрын

    There aren't any reasonable sources to these claims. This is just liberal b.s.

  • @zeratulrus142

    @zeratulrus142

    5 жыл бұрын

    @@Maxfr8 they are literally listed in the description.

  • @Mechadude32

    @Mechadude32

    5 жыл бұрын

    The amount of sources cited makes this kinda unworkable

  • @lizageorge8923
    @lizageorge89235 жыл бұрын

    Look I love SciShow, but sometimes the sources list is really difficult to sort through. Even if you don't number it, could you at least separate the links by subject? Many links don't show the topic in the address. I know Kurztezart (omg ik I didn't spell that right but you know what I mean ^^;) does that.

  • @jwolternova1051

    @jwolternova1051

    5 жыл бұрын

    y it's kurzgesagt

  • @lucas29476

    @lucas29476

    5 жыл бұрын

    Thanks Li. I completely agree

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    I think most sources don't address everything they say, but specific points. Like when they say that there's been a demographic bias, there's maybe one source for just that claim. Then when they say there's not much diversity amongst researchers, they have a source just for that. And finally when they say there's a lack of data on other genetic groups, then they have a source (or a few) for that. And then only the video brings it all together into one, like if you were writing a paper

  • @lizageorge8923

    @lizageorge8923

    5 жыл бұрын

    @@lucas29476 hey there's someone on my scioly team has the exact same name as you! Small world huh

  • @morgen_21
    @morgen_215 жыл бұрын

    There are way more non European people and countries than European people and countries in the world. Just go to all the non-European countries and gather all the genetic data from their labs and scientists.

  • @Azknowledgethirsty

    @Azknowledgethirsty

    5 жыл бұрын

    Sadly only Europe, the Americas, China, Korea and Japan have large enough databases, the other countries are lagging behind in this research, understandably.

  • @hliask903

    @hliask903

    5 жыл бұрын

    Also, European populations aren't as monolithic as Americans often think. Southern Europeans and Northern Europeans are really different in many characteristics. And Southern Europeans, while considered technically "white" are underepresented (Still not as much as people of African or Asian ancestry though).

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    @@hliask903 This is true. Also, back in the USSR days there were many, many medical studies and innovations that included Slavs. But since the fall, and innovation in new medical and genetics science, Slavs are not being included as much in mainstream studies anymore. It's quite difficult to research when most major genetics research organizations are in 5 or 6 countries. (Germany, US, Canada, UK, China, Japan, and a little less so in France)

  • @freman

    @freman

    5 жыл бұрын

    @@Azknowledgethirsty how is that Europe, the Americas, China, Korea or Japans fault? They can make their own databases. It's not like any of the mentioned countries are preventing the others from researching.

  • @Azknowledgethirsty

    @Azknowledgethirsty

    5 жыл бұрын

    @@freman I didn't say it's anyone's fault, this kind of thinking implies that there are good and bad countries when in reality its just natural selfish behavior, I never claimed that they're unethical

  • @stevencampbell7394
    @stevencampbell73943 жыл бұрын

    As a scientific researcher who is also a POC? This video is GREAT!!!

  • @rei_cirith
    @rei_cirith5 жыл бұрын

    I mean, there are countries outside of Europe/US that have medical studies. Is it just not sufficient to make up for the data?

  • @SG-bp4lg

    @SG-bp4lg

    5 жыл бұрын

    Zimbabwe isn't exactly full of highly trained and educated scientists with access to the tools to perform genetic testing.

  • @SG-bp4lg

    @SG-bp4lg

    5 жыл бұрын

    @@Draolord11 "Best economy in Africa" is like saying "Dryest fish in the ocean"

  • @SJ-kg4wp

    @SJ-kg4wp

    5 жыл бұрын

    Jonathan Bowen So you expect people of color from Western countries to fly to countries in Asia and Africa to receive medical attention because their own countries failed to do proper research that would include more than just white people?

  • @marymimi11

    @marymimi11

    5 жыл бұрын

    I'm mixed race, so a study done in Kenya wouldn't help much, but studying 37 million black people in the USA would. . .

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    Other countries often just don't have enough funding for this kind of thing. Hopefully the progressively reduced costs will help even things out in the future

  • @LolUGotBusted
    @LolUGotBusted5 жыл бұрын

    I read that as "Eugenics has a Diversity Problem"

  • @XxRestlessGamerxX

    @XxRestlessGamerxX

    5 жыл бұрын

    It's ironically one of the more diversely held ideas in human history.

  • @Ag3nt0fCha0s

    @Ag3nt0fCha0s

    5 жыл бұрын

    Dein Fuhrer is dissapoint.

  • @deep_fried_analysis

    @deep_fried_analysis

    5 жыл бұрын

    That is exactly why this video exists, to highlight that problem.

  • @zes7215

    @zes7215

    5 жыл бұрын

    pskn s infeiror

  • @DrPonner

    @DrPonner

    5 жыл бұрын

    genomics is eugenics?

  • @TheTenthBlueJay
    @TheTenthBlueJay5 жыл бұрын

    Stefan: "It's just that different individuals have different differences." Me: *Pretends to understand*

  • @TheElusiveReality

    @TheElusiveReality

    5 жыл бұрын

    he means that each individual only varies a little, but what exactly varies is different in each person. For one person the variation could be in a gene to do with blood cell production, for example, and in another person the variation is in a gene related to eyesight. Different populations could be more prone to different types of variation.

  • @youteubakount4449

    @youteubakount4449

    5 жыл бұрын

    If I only have different eye color than what's in the reference genome and you only have a different skin color, we have different differences, but both of our differences are not represented and we have few differences. But if you count the number of possible differences you can find it can add up to a big amount.

  • @violet-trash

    @violet-trash

    5 жыл бұрын

    So instead of focusing on race, we should just expand the sample size with random selection.

  • @aleka..

    @aleka..

    5 жыл бұрын

    @@violet-trash nope, because some groups can have more of those similar differences and it might be (medically) important to know. Did you even watch (listen) the video? 🤔

  • @violet-trash

    @violet-trash

    5 жыл бұрын

    @@aleka.. Yes, he stated that there wasn't specific genetic differences between races, just differences between individuals. Are you sure _you_ watched (or listened to) the video? 😉

  • @OceanAce
    @OceanAce5 жыл бұрын

    Two words: Henrietta Lacks.

  • @azmanabdula

    @azmanabdula

    5 жыл бұрын

    Immortality has its drawbacks

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    I really thought they were going to mention her. Getting consent is a moral obligation, not a matter of choice

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    @@azmanabdula You do know that woman died from cancer, right?

  • @hliask903

    @hliask903

    5 жыл бұрын

    @@limiv5272 Yeah he just meant that her cells are immortal and still widely used in research. Still kinda distasteful though. She didn't have a say in any of that.

  • @cecesoclean4591

    @cecesoclean4591

    5 жыл бұрын

    a hero

  • @jmoreland4
    @jmoreland45 жыл бұрын

    More data is more good

  • @Baigle1

    @Baigle1

    5 жыл бұрын

    just dont give it to beurocrats

  • @Makem12
    @Makem125 жыл бұрын

    While it would be beneficial to include more diverse populations in the research, most of the main research locations are in countries dominated by people of European ancestry. In our current era of history, most of the non-European dominated countries are too poor to contribute much to the research. It's a matter of resource allocation. Our focus should be on incorporating those groups into studies while minimizing the extra cost of resources.

  • @TeeTee-bz3pv

    @TeeTee-bz3pv

    5 жыл бұрын

    Makem12 that doesn’t explain why the US has this problem. People of color are treated differently. It is well documented that people of color pain isn’t taken as serious of white people. Racism still is influencing the medical world.

  • @katiekichula5129

    @katiekichula5129

    5 жыл бұрын

    Makem12 I work in genetic research and there is currently a huge emphasis being placed on filling these gaps in knowledge - it’s made difficult by importation laws and the regulation and protection of human subjects

  • @o76923

    @o76923

    5 жыл бұрын

    I think you are confused about how diverse the US and Europe are. Minorities aren't some strange phenomenon that you hear legends about but never witness. Hell, most of our research is done in big cities. Chicago is only 31% non-Hispanic white, LA is 29%, 35% in New York, 36% in Atlanta, and so on. They absolutely have access to racial minorities. They just have history, outreach, and methodological issues causing racial bias.

  • @Ikajo
    @Ikajo5 жыл бұрын

    European descent is quite vague in and of itself. Europe is fairly diverse with variations depending on where you live. Northern Europe, Eastern Europe, Southern Europe and Western Europe all have some distinctive traits.

  • @therainbowsonicbrony

    @therainbowsonicbrony

    5 жыл бұрын

    Ikajo you are missing the point entirely, while not every European is the same looking at the differences between Europeans vs the differences of other cultures evolved from other parts of the world in comparison is massive, what works for Europeans won’t necessarily work for Africans and Asians While Europeans are all different they undeniably have some similar genetic lineage that the rest of the world doesn’t have any connection to

  • @elreytriton

    @elreytriton

    5 жыл бұрын

    You know exactly what he meant. Pale White folks. Anglo Saxons. From britain to germany to finland. Not the tan whites that get reminded theyre outsiders of arab descent when they piss the wrong person off. *most whites in america are german and british descent. they used to call them WASP, white anglo saxon protestants before they started letting other europeans into the white society in the early 1900s

  • @Ikajo

    @Ikajo

    5 жыл бұрын

    @@therainbowsonicbrony I'm not missing the point, I understand it perfectly well. What I'm saying is that European descent is not one-size fit all. Of course more diversity is needed. I'm all for it. But a Norwegian person won't have the same genes as a Spanish person who won't have the same genes as a Bulgarian.

  • @Ikajo

    @Ikajo

    5 жыл бұрын

    @@elreytriton Except that is not accurate. You can't call people from the Mediterranean pasty white. Eastern Europeans has more in common with people from west Asia. Diversity is needed, I don't argue that. But Europe is not unison. After all, the Hispanic also have European descent. From southern Europe.

  • @KateeAngel

    @KateeAngel

    5 жыл бұрын

    @@elreytriton Funny you mention Finland nearby with Anglo-Saxons. Finland has the most unique genetic composition in Europe, very different from other Europeans. Some Indians have more similar haplogroups to Anglo-Saxons than Finns do

  • @sebastianelytron8450
    @sebastianelytron84505 жыл бұрын

    *sees the like/dislike ratio* : Poor Olivia, why does she get so much unwarranted hate? *hears Stefan's voice* : wait a minute, what's going on here?!? *reads the title* : oh, the **D** word... at least the comment section will be fun!

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    We all know why they hate her. And those people can go have a second stroke.

  • @jezreelmartinez9800

    @jezreelmartinez9800

    5 жыл бұрын

    @@greymind9815 why do people hate her?

  • @davisoares7174

    @davisoares7174

    5 жыл бұрын

    @B-1LL more like her voice

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    @B-1LL and she could still pull more game then you incel.

  • @oscarbright8218

    @oscarbright8218

    5 жыл бұрын

    Julia's the only one that could've pulled this video off

  • @Jackpkmn
    @Jackpkmn5 жыл бұрын

    When i first thought of the possibility of this happening i then thought "naw those people are way smarter than i am there is no way they would leave such a huge variable twisting in the wind." Glad the world is much worse off than my child brain imagined it would be.

  • @Risulfur
    @Risulfur5 жыл бұрын

    I did :O when I saw the source list in the description.

  • @Skylancer727

    @Skylancer727

    5 жыл бұрын

    Damn!

  • @galladeguy123
    @galladeguy1235 жыл бұрын

    There's no way this comment section is going to be civil.

  • @Blaze6108

    @Blaze6108

    5 жыл бұрын

    Would help if people watched the video instead of judging it by the word "diversity".

  • @mickles1975

    @mickles1975

    5 жыл бұрын

    From what I've seen it seems fine. In fact a lot of comments are like yours, pointing out that they think the comment section is going to be a shitshow. I guess a scishow intern is on point removing the rude comments.

  • @emperortgp2424

    @emperortgp2424

    5 жыл бұрын

    @@mickles1975 Which makes the disproportionate amount of dislikes even more baffling.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    You shouldn't have to be civil with reactionaries, there smooth brained subhuman afterall.

  • @JonO387

    @JonO387

    5 жыл бұрын

    @@mickles1975 If they're suppressing ideas by removing comments I'm out. Surely SciShow wouldn't be that Draconic.

  • @DanskerneFraDanmark
    @DanskerneFraDanmark5 жыл бұрын

    it is like the research is done by them with all the money

  • @HaartieeTRUE

    @HaartieeTRUE

    5 жыл бұрын

    "all the(ir) money"? is that what you meant to say ?

  • @macsnafu
    @macsnafu5 жыл бұрын

    This is still *SciShow*, right? Recent videos are starting to make me wonder.

  • @KnightRaymund

    @KnightRaymund

    5 жыл бұрын

    Why?

  • @AverytheCubanAmerican
    @AverytheCubanAmerican5 жыл бұрын

    This is gonna be a fun comments section.... *grabs popcorn*

  • @StudioUAC

    @StudioUAC

    5 жыл бұрын

    don't think you're ever better than anyone else.

  • @AverytheCubanAmerican

    @AverytheCubanAmerican

    5 жыл бұрын

    @@StudioUAC It's a joke mate

  • @zes7215

    @zes7215

    5 жыл бұрын

    wrg

  • @j.hypolite5163

    @j.hypolite5163

    5 жыл бұрын

    so so many idiots. the world amazes me

  • @culwin

    @culwin

    5 жыл бұрын

    Why do you spam these comment sections with your crap all the time?

  • @trafalgarlaw8373
    @trafalgarlaw83735 жыл бұрын

    We need diversity in the database. For scientific reasons, not ethical ones. I think everyone agrees about the scientific part. Adding the ethics aspect, and the end about diversity among researchers are what will drive this comment section.

  • @SleepyFen

    @SleepyFen

    5 жыл бұрын

    Completely agree.

  • @imporia

    @imporia

    5 жыл бұрын

    Unfortunately that's not really true. Reasonably smart and well-intentioned people can disagree on how diversity in researchers will or won't impact research, but a lot of the vileness in the comment section is coming from people angry that "WE have to fix the everyone else's problems", because they think it's bad that scientists care about non-white people

  • @papa_pt

    @papa_pt

    5 жыл бұрын

    @@imporia nope. That's your imagined divisiveness

  • @morgen_21

    @morgen_21

    5 жыл бұрын

    @@imporia Thanks for caring, but poc don't need to be saved by white science.

  • @Randomgen77

    @Randomgen77

    5 жыл бұрын

    Ethics is pretty important to keep in our science, though. Science without ethics can get pretty warped, and I think it’s relevant in any scientific pursuit or discussion to talk about ethical ramifications and factors alongside more “scientific” rationales.

  • @ratatataraxia
    @ratatataraxia5 жыл бұрын

    Is anyone surprised by this?

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    No, but it's still important to talk about this

  • @nuadathesilverhand3563
    @nuadathesilverhand35635 жыл бұрын

    Why am I receiving a notification for a video that's been out for a week, on a channel I'm not subscribed to? * insert confused Jackie Chan *

  • @glemmstengal
    @glemmstengal5 жыл бұрын

    So you're saying all races of humans AREN'T the same?

  • @FantasyUnited04

    @FantasyUnited04

    5 жыл бұрын

    It might be because you use ancestry.com instead of tinder, but typically individual members within a species do have genetic differences. Only morons (& strawmen) claim otherwise.

  • @jasper3706

    @jasper3706

    5 жыл бұрын

    @@FantasyUnited04 I was going to respond to this but I can't beat that savagery

  • @lucillefrancois150

    @lucillefrancois150

    5 жыл бұрын

    Not understanding that a species can be diverse without that causing massive differences within said species, like differences in behaviour and intelligence, is just proving that you don’t care about actual science. Human populations within different areas and that breed with different groups are gonna end up having differences like what diseases impact them and how; but if they all have mostly the same problems like how to get food, clean water, and shelter, then they’ll not see any major genetically caused differences in intelligence or behaviour.

  • @rafaellisboa8493

    @rafaellisboa8493

    5 жыл бұрын

    they're not "races", they're ethnicities ethnic groups are different

  • @imporia

    @imporia

    5 жыл бұрын

    @@WrathAdaft519 ah yes the difference in intelligence between a golden retriever and chinchilla is exactly the same as the differences between a black person and a white person. Now I get it, the reason that I struggle with quantum mechanics is because somewhere in my ancestry I just have some black people dna in me

  • @NethDugan
    @NethDugan5 жыл бұрын

    Medicine and clinical trials have also had issues with women. How things as diverse as autism and heart attacks can present in different ways - but people only look out for or recognise those commonly linked to men. Things like different metabolisms. Also an issue for people of different sizes - with some medications not working as well for larger people and it not being talked about. I'm sure there's a ton of other areas. In short, research needs to include people of all backgrounds and body types to get a good handle on how things work for everyone. And teach that. Make that info available.

  • @KiyomiNight

    @KiyomiNight

    5 жыл бұрын

    ​@@ChaosSwissroIl But they don't really outnumber girls. The statistics are wrong because only the male symptoms have been studied extensively. Girls are constantly misdiagnosed because we present differently than boys do. That's the whole point Neth was trying to make. When I was a teenager I was diagnosed with depression because of my social isolation but I've never been depressed and my isolation was self-inflicted because being around other kids was exhausting and gave me migraines. I wasn't diagnosed with ASD until adulthood when I read about it online and decided to talk about it with a psychologist.

  • @KiyomiNight

    @KiyomiNight

    5 жыл бұрын

    ​@@ChaosSwissroIl That's hard to say simply for that fact that girls tend to be misdiagnosed or undiagnosed so having a precise statistic right now is unlikely. Tony Attwood has a great youtube video about girls with Aspergers (now classified as ASD in the DSM 5) and how they present differently than boys. If you have time, you should give it a watch.

  • @Ikajo

    @Ikajo

    5 жыл бұрын

    @@ChaosSwissroIl The differences between male and female brains are lesser than the differences between people of the same sex. Most prominent differences can be explained by neurological plasticity. Meaning that upbringing and social conditioning plays a far greater role in how the brain develops than development during gestation. Which is also why early diagnosis and habilitation can do wonders for a child's continued development. It won't make the condition go away but it does help with coping and handling different situations. Besides, women also produce testosterone. There is even a medical condition causing over-production of androgens in women.

  • @kelley0815

    @kelley0815

    5 жыл бұрын

    Waa! Waa! Waa! Quit bitchin and get to work

  • @Ikajo

    @Ikajo

    5 жыл бұрын

    @@ChaosSwissroIl Artificial? More artificial than to assume boys are naturally more interested in cars and girls are more interested in horses? Because that's what the studies you mention pretend is the case. And we can't compare to other species either, that's even more silly. We are not chimpanzees. The brain change in correspondence to our environment.

  • @Duke00x
    @Duke00x5 жыл бұрын

    Most genome studies were done in mostly european countries. It kind of goes without saying that this would lead to majority european test subjects.

  • @HaartieeTRUE

    @HaartieeTRUE

    5 жыл бұрын

    yes... its almost like …. THAT'S THE LOCAL POPULATION, WHERE THIS TESTS ARE CONDUCTED.... huh

  • @Duke00x

    @Duke00x

    5 жыл бұрын

    @@HaartieeTRUE Yes. I mean I am not saying we don't need more diverse samples. Just that if the tests are done in countries that are 70% or more European than 70% or more of the samples are going to be european. You don't need the whole "minorities don't trust because of past wrongs" (not saying that doesn't exasperated the problem only that it is likely not the main reason for the problem) rigmarole to explain it.

  • @lucillefrancois150

    @lucillefrancois150

    5 жыл бұрын

    Because no studies are ever purposefully done on minority groups within a population. We simply can’t ask that to happen more, or question why it doesn’t already happen more despite people saying it would happen more almost 30 years ago. No, we can only work on the majority population and never question why.

  • @nw932

    @nw932

    5 жыл бұрын

    @@lucillefrancois150 No one is stopping anybody from doing genetic research.....

  • @milesm9564

    @milesm9564

    5 жыл бұрын

    Duke00x Maybe your idea of Western is white but there is a huge percentage of colored people who live the Western societies, they have just been previously excluded.

  • @wsc31
    @wsc315 жыл бұрын

    It is hardly surprising to find that scientific research conducted in a given society will find the majority of that society are represented in the findings of that research. If such research was conducted in Africa it would be reasonable to expect to find the native population would be the majority of those studied. I expect the same can be said of any country or society that they are most likely to study their own population before looking elsewhere to do additional research on minority communities. Additionally those who are supporting and paying for said research are most likely to be interested in how it applies to them. It would be instructive to find if research done outside the Western, Chinese, Japanese and Indian societies is more "inclusive" of minorities.

  • @bobsmith9177
    @bobsmith91775 жыл бұрын

    Me and my medical genetics degree are rolling our eyes 🙄

  • @LEDewey_MD
    @LEDewey_MD5 жыл бұрын

    There are many excellent comments here, and some are pointing out that, of course, if research is being done in Western nations, that it is not surprising that most of the participants and research tend to focus on Caucasians "by default", as if no real discrimination or exclusion of people of color is occurring. As a physician who has cared for thousands of patients at 3 Michigan hospitals, I can assure you that blatant racism, (and to a lesser extent, sexism), by both doctors and staff, is very much alive and well - and most medical research is based in hospitals. (E.g., black patients are frequently treated like they are drug-seeking addicts when they justifiably require pain medicine, or not being offered the same advanced or expensive care that is automatically offered to a white patient - even when they have identical health insurance.) I think some efforts are being made to address this, but there is still a lot of work to do. Great video, SciShow!!

  • @morgen_21

    @morgen_21

    5 жыл бұрын

    I always suspected that most physicians, especially physicians in Michigan were racists. Finally now, based on your iron clad anecdotal evidence, I can rest assured that my intuition was more than a hunch.

  • @Monojoe

    @Monojoe

    5 жыл бұрын

    @@morgen_21 classic

  • @azmanabdula

    @azmanabdula

    5 жыл бұрын

    @@morgen_21 Dont blame a doctor for your cultures problems We dont blame you for your cultures problems

  • @azmanabdula

    @azmanabdula

    5 жыл бұрын

    @@Monojoe Classic racist pretending to find racism everywhere, trying to analyze human behaviour while overlooking their own

  • @morgen_21

    @morgen_21

    5 жыл бұрын

    @@azmanabdula My comment was obviously satirical comedy. You don't know anything about me or my "culture". Also, when you say "we", who else are you talking about, or are you more than one person?

  • @pdreding
    @pdreding5 жыл бұрын

    I'm happy to see this wasn't sponsored by a genetic testing service. Opt-in paid services can't be making the register more balanced.

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    It's important to note that those genetic profiling services don't sequence genomes, they use microarrays. This means they're only looking at a small portion of the genome, and they can only find the types of variations they're looking for. Therefore their data can't be used for studies trying to get new information about whole genomes.

  • @thstroyur
    @thstroyur5 жыл бұрын

    Tayloring references to specific subgroups is sure to cut some corners, but ultimately I feel "precision" medicine will really take off only with cheap and fast enough genome-sequencing tech for widespread _individual_ diagnosis; that way, you solve two problems at the price of a big one

  • @thstroyur

    @thstroyur

    5 жыл бұрын

    Plus, I realized there might be bad consequences for, e.g., drug regulation with too much "diverse" research; know those paper slips that come within a med's box? Some are practically a book already; can you imagine how they'll manage to fit them in tiny boxes if we expand them to include ever more ethnic-specific data? Those things should go to a digital database (if not already), and _doctors_ should have to go through 'em, not the patients, anyways Again, having the extra data won't hurt (AI problem), as long as the subgroup data don't overfit the individual data and lead to _worse_ diagnoses - Statistics is a fickle mistress, folks...

  • @smolsnek14
    @smolsnek145 жыл бұрын

    Problem: Black people aren't taking DNA tests Solution: Replace researchers with black people. *CONFUSED*

  • @ChrisBryer
    @ChrisBryer5 жыл бұрын

    So... You are saying that race and ethnicity are in fact a thing?

  • @TheJuanTrueKaiser

    @TheJuanTrueKaiser

    5 жыл бұрын

    Chris Bryer race is a social construct. It’s a political category. Genetics is real. Race is not even a genetics term. Just look how race is used throughout history and it becomes incredibly obvious.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    @@TheJuanTrueKaiser trying to explain it to these smooth brained people is frivolous, just direct them to creators.

  • @lucillefrancois150

    @lucillefrancois150

    5 жыл бұрын

    Haploid groups are real, and in biology are generally just called races. They are not however anything like the laments idea of races. For example: There’s some groups of black people on islands off the coast of india that are more closely related to tibetans and the ainu than any other group. According to the laments idea of races they’re black, so they’re closely related to black people, but that’s that true. What group goes in which “race” is far more difficult to tell than most people can accomplish. There’s also how race impacts the people. And for the most part: It doesn’t. It impacts things like diseases, but most things like intelligence and behaviour have no good evidence that they’re related. As far as science is concerned intelligence is related to education and behaviour is related to a list of factors like education and economic status.

  • @ChrisBryer

    @ChrisBryer

    5 жыл бұрын

    ​@@TheJuanTrueKaiser Its more complicated then that. Just cuz race it a broad term and has become problematic does not mean its not real.

  • @ChrisBryer

    @ChrisBryer

    5 жыл бұрын

    ​@@greymind9815 That was extremely rude. What the hell is your problem?

  • @Ceruleanturkeyz
    @Ceruleanturkeyz5 жыл бұрын

    For real though people die because of reasonable lack of trust in medical professionals. The fact that the lack of trust is justified given documented differences in care and mortality rates I think something like this video is good way to show that the problem is more wide spread then just thinking your doctor doesn't care about you. The system excludes diversity. That has to be fixed.

  • @Talladarr
    @Talladarr5 жыл бұрын

    5:36 Look, based on the information needing additional genetic data on the other populations on this planet is a must; however, diversity of skin color=/=diversity of perspective or thought. A rich black guy in the US and a poor Afrikan aren't going to have even remotely the same "perspective" on any relevant genetic studies on the mean. The same can be said for Asians, Native Americans, Middle Easterners or Caucasians. This second part of the argument breaks down.

  • @Katiecatsy

    @Katiecatsy

    5 жыл бұрын

    the fist thing I do is think in relation to what he mentioned is this, because there is a history of colored people being abused by white scientists, having more scientists or color would promote trust and make them more likely to participate in studies. it might also add more perspectives as to how to approach research since different backgrounds could diversify starting angles / ideas. it might benefit everyone.

  • @Talladarr

    @Talladarr

    5 жыл бұрын

    @@Katiecatsy What part of diversity of skin color=/=diversity of perspective or thought was difficult to grasp? Sure, a black kid is going to have a greater chance of growing up in a primarily poor, black neighborhood, but that doesn't mean that a poor Asian or Caucasian can't grow up there and have the same/similar perspective. Again, the second part of the argument breaks down. I'm not arguing against the first part, how is that hard to grasp?

  • @sasidharankarthikeyan3798
    @sasidharankarthikeyan37985 жыл бұрын

    And the video is USA centric.

  • @adroitdroid5989

    @adroitdroid5989

    5 жыл бұрын

    athreyum kooduthal centric alla kurzegast is much more eurocentric while pbs is a complete americophile

  • @spindash64

    @spindash64

    5 жыл бұрын

    To be fair, given that the US has a larger population of PoC than basically any country in the EU, and more resources to work with than much of the Southern Hemisphere, it’s in a good position to fix this situation. One of the best, in fact (outside of Japan’s good resources for research, but even if that fills out another group, iirc, they’re among the most homogeneous groups on earth, thanks to a long period of isolationism)

  • @sasidharankarthikeyan3798

    @sasidharankarthikeyan3798

    5 жыл бұрын

    @@spindash64 I agree that the USA is the most diverse country. But the sample could leave out many people groups like, south American natives, non-west Africans etc. If at all nurture has any bearing on the DNA, things could get more complicated.

  • @declaringpond2276

    @declaringpond2276

    5 жыл бұрын

    @@sasidharankarthikeyan3798 Well, PBS is also a US government funded program... So, you know, they might be paid to be more US focused

  • @sasidharankarthikeyan3798

    @sasidharankarthikeyan3798

    5 жыл бұрын

    @@declaringpond2276 To be frank, I didn't know that PBS is funded by the US govt. Now, I can understand why it is so US-centric. Thanks.

  • @fredriks5090
    @fredriks50905 жыл бұрын

    Meanwhile in the comment section; *Literal clown fiesta rodeo show*

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    Nobody wants you here you dumb reactionaries.

  • @michaeleisner4758

    @michaeleisner4758

    5 жыл бұрын

    Grey Mind Triggered much?

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    @@michaeleisner4758 says the people that flood a video when they place the word diversity in its title.

  • @michaeleisner4758

    @michaeleisner4758

    5 жыл бұрын

    Grey Mind Nope it just seems that you’re triggered with those insults. Insults won’t get you anywhere in life

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    @@michaeleisner4758 yes thank you, there is possible no way I couldn't have know people dont like bieng insulted. Your big brain intellegence is impressive Sir. And such insult that I made clearly shows my triggeredness by the clear and distinct word dumb. Being annoyed that race realist flood your chat or better know as trigered is also one of the greatest ways to teare a leftist a new hole and obliterate them with the stick of facts and logic because clearly calling someone "triggered" is the best come back ever. Yes I know the cacasian race to be the best to there wonderfull bone structue. Thank you. You smooth brained reactionary.

  • @pichu3186
    @pichu31864 жыл бұрын

    Does being mixed race add another issue to diagnosis and finding a working cure? Are mixed race people more likely to react like one race over another or a mix of both when doing tests on them?

  • @edi9892
    @edi98925 жыл бұрын

    I guess that prior 2015, it was pretty hard to find an African test subject in e.g. Germany... Of course, you can request samples to be sent from the other side of the world, but testing new medicine on a diverse cast of test subjects would be a logistical nightmare, especially if you had to involve many hospitals from over the world to cooperate, despite having different cultures of bureaucracy...

  • @bogwife7942

    @bogwife7942

    11 ай бұрын

    black people also live in germany my guy

  • @jinbiezel683
    @jinbiezel6835 жыл бұрын

    I don't think "recruited" is the right terminology. Like, not even in the same universe remotely close! Not only were these men Not told that they were being purposely INFECTED with a serious and deadly sexually transmitted disease. But they were told that what they were being treated for was "bad blood". In the end, none of them were even given the proper treatment for the Disease, which caused deaths, their wives (who were also infected), and some sadly even passed it on to their children. The criminality of this "experiment" is ridiculous! The cretins responsible for and administers of this so-called "experiment" should have had to be "experimented" on themselves. I think this would have been the only appropriate punishment.

  • @rrs1550

    @rrs1550

    5 жыл бұрын

    and at that time..they qualified themselves as the smart ones. aka 'educated'

  • @ICantSpellDawg
    @ICantSpellDawg5 жыл бұрын

    That's why it is called "Western Medicine"

  • @ICantSpellDawg

    @ICantSpellDawg

    5 жыл бұрын

    @Cool Breeze en.m.wikipedia.org/wiki/Western_world

  • @VVabsa

    @VVabsa

    5 жыл бұрын

    Cool, only thing we have to do now is the get the POC motivated enough to get into that field of research so they can help people.

  • @Azknowledgethirsty

    @Azknowledgethirsty

    5 жыл бұрын

    Latin America is western and I'm suspecting there arent much studies on Colombians, slavs are western aswell Besides its no longer called western medicine but modern medicine in contrast to traditional medicine, homeopathy is european traditional medicine, Chinese traditional medicine etc So there is nothing western to this, and even if it were, large parts of the west are missing

  • @Shaden0040
    @Shaden00405 жыл бұрын

    Maybe what needs to be done is that every country needs to sequence the genome of every child born in that country. and have it on file for the lifetime of that person. Once that person has died it can then go into the general population genomes sequenced for the world. This needs to be a voluntary sequencing OKed by the parent(s) of said child and reaffirmed by that child when they reach the age of majority in their country. These genome sequencing needs to be shared between countries if the parents(s) and child move to a new country. And shared with the new country. If each country can do a census of its population each year it can cretainly do a genomic census as well on all of its inhabitants.

  • @Seadalgo
    @Seadalgo5 жыл бұрын

    Time and reduced cost will give us time to play catch up with increasing effectiveness with every leap forward. And that's said as a PathA in next-gen sequencing research and US Citizen of Dominican origin

  • @Seadalgo

    @Seadalgo

    5 жыл бұрын

    The same way we parsed out GFR for Europeans and non-Europeans decades ago

  • @TrichterNET
    @TrichterNET5 жыл бұрын

    I was trying to figure out why so many people disliked the video, But once 5:36 came around it became clear. I agree that we need more researchers in the field, but do you care to explain further how the culture of the researchers will change the results of research? (COMMENTS THAT RESOLVED THE ISSUE) TRiG - Also, you clearly didn't listen to the rest of the sentence, which also answered your question. The clue's in the word "since". michael hopper - Ok, I see. I needed to play that last part over a few times. I'm still not too sure about the different perspectives part because usually you want to set aside your bias in order to obtain good data, Culture influences your bias. I guess it's better to have multiple sets of biases rather than just one, now that I think of it we can just compare all the different results and look for consistencies in the data and pin point where the bias comes in.

  • @two-face1041

    @two-face1041

    5 жыл бұрын

    michael hopper humans....if I am a researcher I tend to choose people who are similar to me when researching big groups unconsciously so that means in theory if people of different cultures and skin tones are the ones doing the research they would choose people are similar to them therefore diversifying the research

  • @spiritxdancer

    @spiritxdancer

    5 жыл бұрын

    A minority researcher is less likely to forget about everyone who isn’t white, and they’ll be more familiar with cultural and class boundaries in their group, making working with those people easier.

  • @qwertyTRiG

    @qwertyTRiG

    5 жыл бұрын

    Were you not listening to the first five minutes of the video, which explain the problem? Do you think that the syphalis experiment would have happened in a world where most researchers were black?

  • @qwertyTRiG

    @qwertyTRiG

    5 жыл бұрын

    Also, you clearly didn't listen to the rest of the sentence, which also answered your question. The clue's in the word "since".

  • @TrichterNET

    @TrichterNET

    5 жыл бұрын

    @@qwertyTRiG Ok, I see. I needed to play that last part over a few times. I'm still not too sure about the different perspectives part because usually you want to set aside your bias in order to obtain good data, Culture influences your bias. I guess it's better to have multiple sets of biases rather than just one, now that I think of it we can just compare all the different results and look for consistencies in the data and pin point where the bias comes in.

  • @Stickywicket
    @Stickywicket5 жыл бұрын

    Is this research mostly done in America?

  • @limiv5272

    @limiv5272

    5 жыл бұрын

    While I don't really know, I'd bet there's a lot of research going on in Europe. Americans tend to forget that "western civilization" doesn't equal USA

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    Most medical research is done in Europe (East and West), and the Americas. More recently China, Korea and Japan have gotten involved and have some big research groups. Arabs, Indians, Native Americans, Austr aborigines, polynesians and Africans (who are really multiple very different genetic groups) don't have their own major medical research organizations so it's rare to see many medical studies include them.

  • @colindupee

    @colindupee

    5 жыл бұрын

    With the socialized medicine of Europe, medical research there focuses on cures and cost-effectiveness. With the mercenary medical system in the US, most research is focused on patentable treatments. Honestly, I'm glad we have both.

  • @notpulverman9660

    @notpulverman9660

    5 жыл бұрын

    Most advanced medical research is done in America(yes).

  • @thescribe5494
    @thescribe54945 жыл бұрын

    I came in expecting the normal REEEEEEE but was kinda surprised. If gynomes can cause such drastically different effects from different types of medications... why isn't more research being done? I'm not fully educated on whether skin pigmentation is honestly that important when it comes to saving lives, but how your base DNA can cause issues or conflict with different medications, then there's an obvious need for a solution. The real question being... why though? What makes the gynome inhospitable to these meds? It's very curious and who knows! Maybe we'll find something new about ourselves in the process!

  • @DasAntiNaziBroetchen

    @DasAntiNaziBroetchen

    2 жыл бұрын

    "I came in expecting the normal REEEEEEE but was kinda surprised" Look again.

  • @bobbyvee260
    @bobbyvee2605 жыл бұрын

    I'm surprised that Japan and China aren't extremely active in the DNA research.

  • @violet-trash

    @violet-trash

    5 жыл бұрын

    I'm pretty sure that the Chinese doctor that went public with their gene editing is far from the first to practice it.

  • @sephikong8323

    @sephikong8323

    5 жыл бұрын

    For Japan I am pretty sure that this is because the public founding goes more towards other fields. As for China, I have no idea (but it is important to remember that not all researches are published so who knows maybe they do and they just don't tell others to keep an edge or to avoid outrages, it is a possibility)

  • @bobbyvee260

    @bobbyvee260

    5 жыл бұрын

    @@sephikong8323 Yes, I don't know. It seems that for scientific prestige alone that they would publish. That is a lot of potential data.

  • @bobbyvee260

    @bobbyvee260

    5 жыл бұрын

    @@violet-trash I was thinking more along the lines of genetic data linked to health issues. Gene editing can bring backlash for the public at large, but information on health and health risks is pretty much all upside.

  • @violet-trash

    @violet-trash

    5 жыл бұрын

    @@bobbyvee260 It still using sequenced genome data either way, which it would seem they've not been idle on obtaining.

  • @rgerber
    @rgerber5 жыл бұрын

    I'm not saying it was Skillshare. ...but it was Skillshare *Alien meme*

  • @williamhardway6436
    @williamhardway64365 жыл бұрын

    Geez. Everyone ought to be included. For accurate data as well as social reasons

  • @zes7215

    @zes7215

    5 жыл бұрын

    wrg

  • @LucidFL

    @LucidFL

    5 жыл бұрын

    How about you stop pushing narratives into science.

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    @@LucidFL Genetics studies need more diverse samples. Researching only Anglos isn't going to get you much info. He's right

  • @MrNotBot

    @MrNotBot

    5 жыл бұрын

    @@luizmatthew1019 Diverse samples are one thing, and diverse researchers are another. The issue lies with the latter and not the former.

  • @michaelrauch8629
    @michaelrauch86295 жыл бұрын

    Very interesting.

  • @ulaskaplan8069
    @ulaskaplan80695 жыл бұрын

    The differences between the genomes of different ethnicities are obvious examples but there are differences even between the members of a family - children and their parents. This is because even if the genes of two people are identical, the expression of the gene can be dramatically different due to accumulated mutations in the genome or epigenetic differences. So, instead of the genome, it is better to focus on the presence of the RNAs and proteins in the individuals. That's why the techniques such as RNA-seq gives way too much detailed and precise information compared to sequencing the genome. As far as I am aware, nucleotide sequence informations are out of date in precision medicine literature.

  • @withCharles
    @withCharles5 жыл бұрын

    Overall a good video. Only suggestion is to change the title, because ultimately it's gonna lead to unnecessary hate and an, admittedly funny, flaming comment section. Something like "Genomics Needs a Greater Diversity in Data", or anything along the lines of addressing the main issue the video itself makes a talking point. Of course if the point of the title was to get people to watch the video with an intentional clickbait, then good job. That being said, keep up the good work SciShow.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    They dont need to change simply because a few smooth brained reactionaries get triggered thay sci show acknowledged reality as in there is racism and discrimination in the world.

  • @withCharles

    @withCharles

    5 жыл бұрын

    @@greymind9815 I do agree, I just simply think that the change would allow for an overall more positive reaction, and be more likely to get people who might be triggered by the word diversity, but may agree with the content of the video, to at least get their drawers out of a wad and listen for a bit, allowing for a, hopefully, more civil discourse. That being said it would also likely make whoever is in charge of getting rid of the truly troublesome comments have an easier time. It's ultimately their decision and they'll do what they want.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    @@withCharles why would you want it to be civil. They sure as hell arent.

  • @DasPlayer2

    @DasPlayer2

    5 жыл бұрын

    The video is titled for clickbait. A massive proportion of SciShow's videos are, and it doesn't matter what the votes look like as much as the views, and thus the ad revenue.

  • @dylanvellut
    @dylanvellut5 жыл бұрын

    It got fine until the 5:40 A researcher does not need a different skin color to diversify his field. He/she has to know the science, question everything until he/she point a weakspot in a theory and prove a better explanation for the observation. Skin color has nothing to do with that

  • @ediblecrayon4989

    @ediblecrayon4989

    5 жыл бұрын

    Ok but if researchers are mostly white they tend to unconsciously study more so on white individuals. Diversifying the scientists can lead to more diversified control groups.

  • @dylanvellut

    @dylanvellut

    5 жыл бұрын

    raya sessoms why « unconsciously » ? We figure out the problem pretty accuratly Western countries, richer ones, have labs in white populated area where people can be studied. Minorities are underrepresented, which implies further studies should be imposed on these minorities to get the datas we lack a black scientist wouldn’t be more or less critical, nor valid, than a white scientist. The most important part is that anybody apply the scientific method and no skin color give an advantage on how to think and rethink properly Moreover, scientists HATE biais, good ones will track any mistakes or errors in their work. I wouldn’t say they are biais free, but neither are non white scientist. So it will not change anything

  • @furkantozan5437

    @furkantozan5437

    5 жыл бұрын

    @@ediblecrayon4989 By your logic, if you were a scientist, you would unconsciously ignore people of a descent other than yours? Wow. I hope you have as little to do with science as humanly possible.

  • @ediblecrayon4989

    @ediblecrayon4989

    5 жыл бұрын

    @@furkantozan5437 not exactly. I was mentioning tendencies.

  • @furkantozan5437

    @furkantozan5437

    5 жыл бұрын

    @@ediblecrayon4989 You were mentioning unsubstantiated tendencies that might as well be just completely wrong to give yourself the illusory validation for imagining a problem in such a way that it's not only imaginary but also racial. Shall we move on to discussing the Flying Spaghetti Monster now?

  • @toddmorningstar4206
    @toddmorningstar42065 жыл бұрын

    You lack an explanation for why both the statement that the difference between individual genomes usually caps at 1% only and the statement that the use of a European genome is less effective for those of non-european descent medically do not contradict each other in the context which they are used. This is something that should not be skipped over.

  • @o76923

    @o76923

    5 жыл бұрын

    Let me try to explain it with an analogy. Pretend the genome is exactly 26 characters long and a capital letter matches the reference genome and a lower case one deviates. We'll also assume each individual has two letters that deviate on average. While any given individual will have 24 capital letters, you can still construct that in such a way that subpopulations differ. For example, maybe white people never have a lower case letter in the GHIJKL range and be twice as likely to have a lower case letter in the QRST range compared to the UVWX and MNOP ranges. That means researchers will pay more attention to QRST and almost none to GHIJKL. That can be a problem in a few ways. You may miss patterns like lower case Q requires a capital H. You could also pay too much attention to RST when STU actually contains the sequence you care about but was not considered because it wasn't in the high variance area.

  • @toddmorningstar4206

    @toddmorningstar4206

    5 жыл бұрын

    @@o76923 Ok, but my point is that an explanation such as this is not given in the video. I myself am already aware of this but others may not be. I am not asking a question, I am giving a critique.

  • @o76923

    @o76923

    5 жыл бұрын

    ​@@toddmorningstar4206, I completely disagree. It is would be a digression over a minute long on the topic of how statistical distributions work to people who don't understand them. Most viewers of the video should either 1. Already know it, 2. Accept that the expert you would trust for an explanation can in fact explain it, or 3. Won't be swayed anyway because their politics already determined whether they agree or not. There were tons of tangents that he could have gone on to explain not critical topics within the video. But none of them would have helped explain the problem, why it's a problem, or what some solutions are.

  • @toddmorningstar4206

    @toddmorningstar4206

    5 жыл бұрын

    @@o76923 You fail to address others that may use this to prove race-biased beliefs. Sure, their political opinions would likely not be changed by this video, but it leaves a loophole that can be used to validate racist claims which such people would relentlessly search for and show to others an out-of-context version. Basically my argument is that the need to clarify is to reduce the amount that the message can be warped.

  • @lucusloc
    @lucusloc5 жыл бұрын

    5:35: classic fallacy, race =/= culture, and culture is what defines perspective. Race is a component of physical aspects, like DNA, but it is a poor proxy for maintaining a diversity of perspective.

  • @mopeybloke

    @mopeybloke

    5 жыл бұрын

    @Leonard Erasmus Race doesn't cause culture, does it? The recognition of races impacts culture as any other grouping.

  • @lucillefrancois150

    @lucillefrancois150

    5 жыл бұрын

    Because it’s so very likely that a white person would be part of the Yoruba culture, and that an asian person would be part of the Navaho culture. It’s not 1:1, but it’s statistically incredibly likely to lead to at least somewhat important differences in culture.

  • @notpulverman9660

    @notpulverman9660

    5 жыл бұрын

    Culture causes race. Race is divergence in populations. Culture causes divergence in populations.

  • @Elohist2009
    @Elohist20095 жыл бұрын

    Another group that showed no side effect from Warfarin: Klingons

  • @joannaleiserson9120

    @joannaleiserson9120

    5 жыл бұрын

    What's a Klingon's favorite battery? Duras-ell

  • @Elohist2009

    @Elohist2009

    5 жыл бұрын

    Zak Arranda 😂😂😂

  • @OriruBastard
    @OriruBastard5 жыл бұрын

    Europeans studying europeans in the 90's. Imagine my shock.

  • @jamesfoster6414
    @jamesfoster64145 жыл бұрын

    This is kind of like clothes sizes we have basic sizes because otherwise old navy would be a 5 square mile building i know it’s not perfect but it’s a cost/ benefit problem

  • @Tepid24

    @Tepid24

    5 жыл бұрын

    Maybe medicine shouldn't be treated as a cost/benefit problem then?

  • @jamesfoster6414

    @jamesfoster6414

    5 жыл бұрын

    Weeb Extraordinaire probably not but I don’t know the financial side of it not just studies but fda approval developing patents production stocking marketing and all the other clerical things that would be a part of having a gene spastic medicine it depends on the percentage of gene specific drugs

  • @lostmybadger
    @lostmybadger5 жыл бұрын

    why did i read the comments.....

  • @joshualee2458

    @joshualee2458

    4 жыл бұрын

    I feel your pain :(

  • @Asdfgfdmn
    @Asdfgfdmn5 жыл бұрын

    Who also read it comics’ diversity problem?

  • @maverick9708

    @maverick9708

    5 жыл бұрын

    apparently nobody else read those comics either

  • @Lwydius
    @Lwydius5 жыл бұрын

    But ... but ... I thought race was a social construct ...

  • @tomlangford1999

    @tomlangford1999

    5 жыл бұрын

    these two things are not inconsistent in the slightest

  • @Lwydius

    @Lwydius

    5 жыл бұрын

    ​@@tomlangford1999 That sounds cognitively dissonant.

  • @brianc5581

    @brianc5581

    5 жыл бұрын

    @@Lwydius Exactly what I thought when I heard it.. Try argueing about difference in IQ between races and all of a sudden races don't exist anymore and you're a racist for even seeing a difference in skin color..

  • @Lwydius

    @Lwydius

    5 жыл бұрын

    @@brianc5581 Yeah, it's science when it suits the agenda, bigoted hateful ignorance when it doesn't.

  • @tomlangford1999

    @tomlangford1999

    5 жыл бұрын

    @@Lwydius nope - 95% of human genetic diversity is irrelevant to race - primarily because Africa is where 95% of human evolution occured and it is only relatively recently that humans migrated out of Africa. Races are not discrete groupings and show a vast amount of overlap - the only reason we think races are so different is because they look different to our eyes and we are biased toward outside looks - but that's not a scientific way of grouping individuals. Are there differences between races? Certainly, but a majority of it cannot be explained by genetic differences alone and is better explained by social differences.

  • @Zappyguy111
    @Zappyguy1115 жыл бұрын

    Guess, as a hybrid, I should volunteer.

  • @ZIEIaou
    @ZIEIaou5 жыл бұрын

    steph curry is a skillshare teacher

  • @itaybron
    @itaybron5 жыл бұрын

    i miss having DNA

  • @TheFish711

    @TheFish711

    5 жыл бұрын

    Same

  • @luissemedo3597

    @luissemedo3597

    5 жыл бұрын

    VIRUS

  • @neonlemurs4865
    @neonlemurs48655 жыл бұрын

    All the people who disliked saw the word diversity and freaked out.

  • @chamodhimanodhya7224

    @chamodhimanodhya7224

    5 жыл бұрын

    @@DK-td2sh there is nothing wrong with having a diverse group of researchers.

  • @TheJuanTrueKaiser

    @TheJuanTrueKaiser

    5 жыл бұрын

    D K And that happens where? Is this the hill you wanna die on to? Lol

  • @MrCordingly

    @MrCordingly

    5 жыл бұрын

    @@DK-td2sh Hi DK, you focused on one part of a 6 minute video, you also dropped that those were suggestions from experts.

  • @billyosullivan4514

    @billyosullivan4514

    5 жыл бұрын

    No it says blacks think differently

  • @Uhlbelk
    @Uhlbelk5 жыл бұрын

    Diversity of skin color does not indicate a diversity of thought, or a diversity of genes. Yes we need more data from more diverse populations to get the most accurate information, and then apply that knowledge accurately, but that doesn't mean limited data and information is bad, just that more is better.

  • @quincy9908
    @quincy99085 жыл бұрын

    This topic doesn't get enough clout (just like most science) so every thing you can to support research in diversity and spread awareness of this problem

  • @secretplatypusperry
    @secretplatypusperry5 жыл бұрын

    SciShow: Comprehensive data representative of a population is crucial for improving genetic research. Dislikers: "I'm going to pretend I didn't hear that."

  • @jamesguinan415

    @jamesguinan415

    5 жыл бұрын

    Why are you so dishonest?

  • @secretplatypusperry

    @secretplatypusperry

    5 жыл бұрын

    Where does he say "unqualified for the job?"

  • @billyosullivan4514

    @billyosullivan4514

    5 жыл бұрын

    No they suggest at the end that race links to your views in other words race determins how you think

  • @Eyerleth
    @Eyerleth5 жыл бұрын

    Absolutely nothing about this is controversial. Greater diversity of data and perspectives is always good.

  • @Kobolds_in_a_trenchcoat

    @Kobolds_in_a_trenchcoat

    5 жыл бұрын

    Thank you.

  • @faramund9865

    @faramund9865

    5 жыл бұрын

    5:38

  • @billyosullivan4514

    @billyosullivan4514

    5 жыл бұрын

    Why does the researcher race matter they said it does

  • @Deontjie
    @Deontjie5 жыл бұрын

    All our breakthrough science discoveries from Africa we keep to ourselves.

  • @spacejaga

    @spacejaga

    5 жыл бұрын

    And if im not mistaken you are white guy from South African Republic with obvious ancestors in Netherlands region :))))

  • @Deontjie

    @Deontjie

    5 жыл бұрын

    @@spacejaga Yes, but there are millions of groundbreaking scientific, engineering and industrial discoveries from Africa that we have successfully hidden from the rest of the world for the past 2,000 years.

  • @yuirick
    @yuirick5 жыл бұрын

    Aight, I'm a bit confused. I looked up some papers on races the other day, and they stated that races in humanity do not exist. I suppose the increase in genetic diversity in research is still useful, but yeah, that's left me somewhat confused.

  • @imporia

    @imporia

    5 жыл бұрын

    what papers did you read on that? taxonomy gets really unclear and vague as you go further down

  • @yuirick

    @yuirick

    5 жыл бұрын

    @@imporia I didn't have full access to any of the articles, but all of the year 2000+ articles on google scholar had the same idea in the abstract, where the genetic diversity was too small in humans to be classified as a race, like we would do in other species. (Like certain monkeys). Here's an example: www.sciencedirect.com/science/article/pii/S1369848613000460

  • @yonatanbeer3475

    @yonatanbeer3475

    5 жыл бұрын

    @@yuirick hm... Interesting.

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    Here's the thing. There's various genetic groups. Haplogroups. Those sometimes vaguely follow race lines, especially in Europe, but they often do not. The Haplogroup D-M174 for example exists in former Ainu territory, the Ryukyuan islands, Tibet, and the Sentinalese islands. Note pure Ainu look almost European even though they are from north Japan. Tibetans look similar to most e asians. Sentinalese look african, though they share about as much in common with them as Indians do. The Haplogroup I exists in most of Europe. You could say this almost a "White" haplogroup. So race does exist? Again, it's more complex. Kurdish people share this, while Portuguese, Galicians, Occitans and Leonese don't. Then there's Haplogroup I1 that pretty much exists only in Germanic countries. So is this a Germanic gene? Well, there's exception. Fins and North Russians have it. Tl;DR Race doesn't really exists, but can sometimes be used to simplify groups that share similar genetic traits, however in many cases it's utterly useless.

  • @yuirick

    @yuirick

    5 жыл бұрын

    @@luizmatthew1019 That was fairly informative, from what I can tell. Thank you. :)

  • @Neoprototype
    @Neoprototype5 жыл бұрын

    Whitecentric ? Oh you mean like SciShow hosts.

  • @derpywoodoo

    @derpywoodoo

    5 жыл бұрын

    Half of their cast (at least of the 4 I can think of off the top of my head) are POC. What are you talking about?

  • @proton8689
    @proton86895 жыл бұрын

    The like-dislike ratio worries me, despite the fact that the video is pretty much standard.

  • @greymind9815

    @greymind9815

    5 жыл бұрын

    The reactionaries hate accepting basic facts like that discrimination and racism is a thing.

  • @General12th

    @General12th

    5 жыл бұрын

    Most of the dislikers aren't actively racist, but if you ask them to even _acknowledge_ that racism still exists and we should do something about it, they'll come up with a dozen justifications for why they shouldn't have to change anything because the system is fine.

  • @matty7834

    @matty7834

    5 жыл бұрын

    @@General12th the system is fine. Sure, there may be some disgusting individuals with racist intent, but these people are few and far between. Also, not wanting equality of outcome isn't racist. There are less black people than white people on the UK for example, so it's expected for there to be less black people as a % in a workplace. Forcing there to be an even split for 'equality' is not equality at all.

  • @misanthropiclusion

    @misanthropiclusion

    5 жыл бұрын

    Racists get real mad when science happens to be about something they dont like

  • @proton8689

    @proton8689

    5 жыл бұрын

    @@matty7834 The video's about genetic diversity in medical research. Where on earth did you get equality of outcome from?

  • @micklepickle0159
    @micklepickle01595 жыл бұрын

    Another problem is insurance companies have a habit of exploitation of genome testing in their insurance policies. Until genome testing is kept private, screw giving that stuff away.

  • @walkingbushie3568
    @walkingbushie35685 жыл бұрын

    That was very interesting. I wasn't even aware of this lack of diversity. What I'm curious about is how does this affect a mixed racial person like me? Will it be more difficult to research?

  • @carissstewart3211
    @carissstewart32115 жыл бұрын

    "We need more data" Absolutely. Yes. "We need more researchers of color." The skin color of the researchers shouldn't matter.

  • @TheJuanTrueKaiser

    @TheJuanTrueKaiser

    5 жыл бұрын

    Cariss Stewart maybe we need this magical thing called perspective? And even if it doesn’t matter... who cares?

  • @carissstewart3211

    @carissstewart3211

    5 жыл бұрын

    @@TheJuanTrueKaiser i care when science begins to bend the knee to politics. Science ought to be objective.

  • @imporia

    @imporia

    5 жыл бұрын

    you're right it shouldn't matter, however people aren't perfect and it seems that most of the researchers who have been working on it so far have overlooked some pretty important details because of their color

  • @DennyVlogs

    @DennyVlogs

    5 жыл бұрын

    The JuanTrueKaiser so different races would have different perspectives? Is that what you are saying?

  • @ShrapnelProductionHD

    @ShrapnelProductionHD

    5 жыл бұрын

    @@TheJuanTrueKaiser in science you dont need to have to achieve a different perspective. this isnt social sciences we are talking about. if the person is the best fit for the position skin color doesnt matter. but if the position is forced in for racial diversity then we have a problem.

  • @SlideRulePirate
    @SlideRulePirate5 жыл бұрын

    But how can this be? People are all exactly the same aren't they?

  • @robertpalumbo9089
    @robertpalumbo90895 жыл бұрын

    Dont forget Shetland and terra de feugue

  • @luizmatthew1019

    @luizmatthew1019

    5 жыл бұрын

    Hobbits don't need genetic testing

  • @BogdanManciu
    @BogdanManciu5 жыл бұрын

    The issue is real, first time research is based on a small dna sample size, because it was expensive and research must blow all that money on a single target dna or gene to be able to get results and get published, it's what we see generally with study replication, nobody does it because it's as expensive as the first study but the results aren't published for lack of innovation. It's a risky move do you go wide and cover your bases but risk not getting results published in time, or go narrow and beat everyone to the patent. It's too bad that they chose to present this from a racial perspective and a progressive historical lens followed up by an diversity , equity, inclusivity argument. Once the process for full genome sequencing drops researchers will use the data. Once China and Europe and Africa invest in more research diversity in studies and samples will solve the problem itsel. The tragedy here is the "monopoly" the US has on medical research, they do pubpish the majority of papers in this field. Europe is investing some money but their investments in London are at risk due to Brexit and the Lübeck Center is still WIP. China has started doing some interesting work, let's hope they continue to get funded. Africa unfortunately hasn't developed their economy at the level where they can fund many of these academic studies, but often do shared research with US groups. It's maybe important to keep journals to better standards of sample size and sample diversity and peer review and the free market will correct fir past narrow results. Rant over.

  • @flibbernodgets7018
    @flibbernodgets70185 жыл бұрын

    I was bracing for some unfounded complaint, but this makes sense. The title does sound like trying to throw around blame though. *Edit: added "the title"*

  • @Nata-rb4vc

    @Nata-rb4vc

    5 жыл бұрын

    Flibber Nodgets how is it throwing blame? It’s literally just science being like, we go where there’s the most data, we have the most data for europeans so we go there. It just happens. And PoC avoid clinical trials because historically we’ve been used as literal guinea pigs. We still have healthcare disparities to this day, look at the postnatal mortality rate blacks vs whites. It’s not a blame game, it’s just systematic distrust and racism my dude. And that’s not the fault of scientists or white people, it’s a fault of the *system* we all have to fix.

  • @spindash64

    @spindash64

    5 жыл бұрын

    It didn’t sound too Blame heavy to me, more “we need to get on this already”

  • @flibbernodgets7018

    @flibbernodgets7018

    5 жыл бұрын

    @@Nata-rb4vc yup, and that's what they talked about. I should have been clearer originally

  • @ActionAlligator

    @ActionAlligator

    5 жыл бұрын

    @@Nata-rb4vc Well, you're blaming the system of course, so you are blaming something, and I don't see any reason to believe there's a problem with "the system," depending on what you specifically mean by that. _"And PoC avoid clinical trials because historically we’ve been used as literal guinea pigs"_ Firstly, assuming they are actively avoiding clinical trials (as opposed to just not taking part in them due to whatever reason, such as ignorance that the trial is even under way, or just neutrally being uninterested, etc.), is that really the reason they're doing so? Do we actually know? And secondly, those are far and away the exceptions, not the rule (being treated as guinea pigs). But yeah, agree on everything else; it's unfortunate that we don't have more data on other groups and it's unfortunate that we suffer the consequences because of it.

  • @Nata-rb4vc

    @Nata-rb4vc

    5 жыл бұрын

    ActionAlligator when I say I blame the system I mean: my mom was born in a different state because blacks weren’t allowed to be born in her county. I mean my grandfather dying because he thought the doctors were trying to kill him with his heart medicine so he didn’t take it. I mean when they send black kids to underfunded schools, then get shot in the streets and everyone blames it on the child that was killed because they looked “suspicious” aka existing while black. I mean the fact that poc have higher poverty rates because of a whole system built in the 1700s that was designed for white men only. A system that prioritizes ownership of land that isn’t ours to keep, that was designed to mute the voices of the masses. I seriously think only a few things’d have to change to make this country a good place for everyone in it, I just think that these changes aren’t popular because white Americans see it as a loss of power. When I say the system, I mean the school to prison pipeline, I mean the systemic distrust of doctors, I mean funding school districts with property taxes. And no one person is responsible for all of that. No one race. It’s a culmination of history, experience, and bureaucracy. And we just need equity, not equality, but equity.

  • @ramennight
    @ramennight5 жыл бұрын

    Well this episode got firebombed.

  • @ramennight

    @ramennight

    5 жыл бұрын

    Or im just talking about how the response to this video is going to get massive downvotes, without any commentary on the who or why.

  • @bazookallamaproductions5280
    @bazookallamaproductions52804 жыл бұрын

    how can 10 percent of a genome not be on the reference genome if we only differ in dna from GORILLAS by about 2 percent?

  • @mysteepulcine2510
    @mysteepulcine25105 жыл бұрын

    I gave my medical files, blood, and urine to the All of Us program! You should too. More data is better.

  • @rrs1550

    @rrs1550

    5 жыл бұрын

    that's the story........aka bs

  • @mysteepulcine2510

    @mysteepulcine2510

    5 жыл бұрын

    @@rrs1550 why would data for research be a bad thing?

  • @janellabaxter3396
    @janellabaxter33965 жыл бұрын

    I have been waiting for SciShow to do a video on the deep methodological problems involved with using genomics to classify human populations into ancestral and racial categories. This area of research employs a diverse range of methods and assumptions, but historians, social scientists and philosophers have been arguing that there are many reasons we should be skeptical that genomics can give us non-circular answers. Please have a look at some of the really important research on this issue. www.sciencehistory.org/profile/ramya-rajagopalan is a great start.

  • @delpresley5015
    @delpresley50155 жыл бұрын

    *Damn* .......those hands in the thumbnail look ashy.

  • @5starview

    @5starview

    5 жыл бұрын

    Das wacist

  • @SageVaughn

    @SageVaughn

    5 жыл бұрын

    Raysist

  • @liamwinter4512
    @liamwinter45125 жыл бұрын

    Itll be fascinating when sickle cell could be wiped from human genetic history.

  • @jumpenjackflash780
    @jumpenjackflash7805 жыл бұрын

    But in the end it shouldn't matter

  • @MineKynoMine
    @MineKynoMine5 жыл бұрын

    > Research done in Europe > Results prioritise Europeans Scishow: DAS RAYCIST

  • @SolveForX
    @SolveForX5 жыл бұрын

    Sounds like Africa needs to be doing more science things, huh?

  • @VVabsa

    @VVabsa

    5 жыл бұрын

    Well, the middle class is on the rise over there. So it ougth to happen soon.

  • @jesipohl6717
    @jesipohl67175 жыл бұрын

    Biggest major hurdle, is that so-called individualised med was never meant to treat a diversity of people, but was rather going to be relevant to so-called "certain demographics", ie racist med, a discredited field reborn. I am so happy people are turning this on its head to open it up to a truly diverse and specific understanding of individual differences which are actually generally significantly greater between any two humans than between any two groups of humans.

  • @somepunkinthecomments471
    @somepunkinthecomments4715 жыл бұрын

    Although I agree with the general message of this video, that being, research needs to be done equally on all races, I find the fact that it focused on black people being underrepresented disgusting. Equality isn't pro black, it's pro everyone. You never even mentioned any race other than white, black, and one tiny reference to puerto ricans. How about asians, indians, middle easterns peoples, native Americans, so on and so forth. Pro black isn't pro equally, even if they're underrepresented, the journey is just as important as the destination.

  • @Twiggierjet
    @Twiggierjet5 жыл бұрын

    I wonder how many people saw the title, went "HURDUR ESS JAY DOUBLE-U'S", disliked and left without actually watching the video?

  • @ixis

    @ixis

    5 жыл бұрын

    Twiggier half, because KZread racism

  • @michaelsinclair9310
    @michaelsinclair93105 жыл бұрын

    Imma gonna leave this comment section before it gets ugly.

  • @EIixir
    @EIixir5 жыл бұрын

    Why don't African and Asian research companies share the data from their own genetic studies?

  • @puppeli
    @puppeli5 жыл бұрын

    This all has been a commonly known problem for years. But at the same time gene technology is becoming cheaper, better and faster, every year. That means that, year by year, solving the diversity problem is becoming easier. And at some point it *will* become a non issue.

  • @greenbeans7573

    @greenbeans7573

    5 жыл бұрын

    If we had medicare-for-all and made genetic testing free no-one would be justified in complaining (if they want to make a dent in the data then they can go get the test done).

  • @LiDARs
    @LiDARs5 жыл бұрын

    This reminds me of his MSG video. Very heavy on the racial undertones.

  • @o76923

    @o76923

    5 жыл бұрын

    It's not an undertone. This is about a real disparity based on race that is causing problems. This is what institutional racism looks like.

  • @ActionAlligator

    @ActionAlligator

    5 жыл бұрын

    @@o76923 Does your immediate family include "people of color?" How many dates have you been on with "people of color" compared to those of European descent? Are your answers to those questions what individual racism looks like?

  • @-4subscriberswithahammerad521
    @-4subscriberswithahammerad5215 жыл бұрын

    I wish we put more of our budget on studies like this an space exploration than in the military

  • @damnthosetorpedos5663

    @damnthosetorpedos5663

    5 жыл бұрын

    @trenbolonely You can cut the fat of a bloated budget, though.

  • @General12th

    @General12th

    5 жыл бұрын

    @trenbolonely Sure you can. Well, Congress can.

  • @mojobob4964
    @mojobob49645 жыл бұрын

    An oversight???! 😂😂😂😂😂 That shits done on purpose

  • @mikelord93
    @mikelord935 жыл бұрын

    How about making medical profiles of all people, anonymised of course, and make the database public. If anyone doesn't want his data made public he can opt out. PROBLEM SOLVED