Gene Silencing mechanism
Gene Silencing - This lecture explains about the gene silencing mechanism by antisense RNA technology. Antisense RNA and RNA interference mechanisms are used to control the expression of desired genes in cell and it can be used to degrade target RNA so that the expression of proteins can be prevented.
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Пікірлер: 115
Best videos ever! Not even our university instructor in Canada explains this well. But your voice seems different a bit in this video.. :) Thanks for your efforts!
@juliamboziphiri5796
Жыл бұрын
How can I apply to your university
The way u explain the things is really commendable... Came to know about your channel last month & started following it & it's really a wonderful experience 😊 Thank you!
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share
Sir can we use GENE EDITING through that molecular scissor means complete removal instead of GENE SILENCING . CAN U PLZ EXPLAIN RELATIONSHIP B/W THESE TWO TECHNOLOGIES
and how do we decide the sequence of mRNA or that particular gene so that we can synthesize antisense RNA to target that gene for gene silencing??
Thank you for giving us amazing lectures and help us clarify our concepts always 🙏
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
HHeyy Sir!! I mean how well you explain..no words for you! i hav been watching your videos since so long..i jst learn frm your videos nd hav been getting gud marks in all my semesters! Thankyou so much..:) I keep on sharing your videos wd my frnz too:)
I can't explain that how much I understand to clear the ..concept to sea yr video ...a great way of learning ..
@shomusbiologyofficial
6 жыл бұрын
Thank you.
Sip plz rpl, why iue body to do knock doen mRNA. How we get complementary RNA. Is the antisense RNA ave no effect?hiw RNAase H decide irs target?
Soon you will have 1 M subscriber 🎊🎊🎊 and I will also be a part of that 1 M 💞 congratulations
I have just heard of this concept, I have an ask can/ how can this be performed in an alive plant like in a natural area? Thanks
Sir Mera aik question h kindly clear kerdy antisnes RNA Jo h wo just m RNA ko hi target kerta r RNA i Jo target kerta h genes r DNA ko
So many errors are there in this video...RNase H degrade RNA in an RNA-DNA hybrid. In this case an RNase L has been cited to act rather than RNase H. Now a days it is said to reside in the Dicer.
+3 1st year se Apke vdo dekh rahi honn, abb Main final year student hoon ,sare video bahat hinn helpfull hai, support you from odiaha. Thank you very much sir.
@shomusbiologyofficial
3 жыл бұрын
Glad to hear that you're getting benefit from my lectures. Please subscribe and share
you are saying that if SOD 1 is mutated or fails to function then it may leads to ALS due to reactive oxygen species which mainly affect brain cells. Why there is need to silence this gene. Suppose if u have already ROS in our body it may affect brain cells which also leads to ALS. How is it possible sir???Please explain.
Thank you sir for explaining this chapter very well... Now it will very easy for me to understand the concept...😄😄 Your videos are always helpful to me...❤️
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share
Will gene silencing work for sufferers of Thalassemia?
Simply delivered knowledge - Thank you, dear!
@shomusbiologyofficial
2 жыл бұрын
You're welcome
How heritable silencing of Gene can be occurred without a change in their coding sequence?
Thank you sir. I have been following your videos and they have been helpful.
@shomusbiologyofficial
5 жыл бұрын
Glad to hear that you are getting benefit from the videos
Excellent
Is this equal to genomic imprinting ??
thank u sir... ur all vedio are very nice and very useful to my study.ur presentation is excellent..
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
Thank for explaining,that was awesome
@shomusbiologyofficial
5 жыл бұрын
Glad you liked it
Excellent video to understand the gene silencing
@shomusbiologyofficial
3 жыл бұрын
Thank you so much for appreciating my efforts
great 😍👍🌼
what is the difference between siARN and miARN
Thank u so much sir for sharing this video...I really needed it.....😊👌👌👌
@shomusbiologyofficial
3 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
Very helpful video sir 👍 thank you
@shomusbiologyofficial
4 жыл бұрын
Glad to hear that you're getting benefit from my lectures
what is the difference between gene knock off and gene knock out
thnx bht acha lec tha
This Video was Helpful, Sir.
@shomusbiologyofficial
4 жыл бұрын
Thabk you
i studied gene silincing on book i was confused later why mRNA is degredaded later .... Watching ur video i got it's importance .. Ur legend Dear ...
@shomusbiologyofficial
5 жыл бұрын
Thank you. Glad you liked my lectures. Please subscribe and share
Pls sir speak loudly it is very useful
Thank you so much sir for this useful information......
@shomusbiologyofficial
5 жыл бұрын
You're welcome
Thank you for such a nice explanation ..help me in my seminar presentation 🥰
@shomusbiologyofficial
9 ай бұрын
You're welcome
Why only Rnase H degrade orginal mRNA why new design is not degraded
It's the best explanation❤️
@shomusbiologyofficial
3 жыл бұрын
Thank you
Very thankful to you sir
@shomusbiologyofficial
3 жыл бұрын
You're welcome
Excellent Sir👍👍
@shomusbiologyofficial
2 жыл бұрын
Thank you
Grt vdo really helpfulll. In which hospitals is gene silencing practised. Pls let me knw. Thq
@shomusbiologyofficial
5 жыл бұрын
Not in hospitals
thank u sir
@shomusbiologyofficial
3 жыл бұрын
You're welcome
Sir ur class is too much helpful for me. is there a video of Bio-genesis of Ribosomes
@shomusbiologyofficial
5 жыл бұрын
No. I will make one soon
i am higly intrested in genetic engineering and molecular biology .....plzz recommend top books for very topics..thank you
@SambitPatra1
5 жыл бұрын
Cell biology by Gerald Karp
You need to turn on the closed caption cause I can't understand what you are saying. Also, what does luciferase do to our DNA??
Thank you so much 😊 Sir🙏
@shomusbiologyofficial
2 жыл бұрын
You're welcome
RNAi or the double stranded RNA technology does not degrade the DNA, it infact degrades the specific mRNA against which the antisense RNA or the double stranded RNA has been incorporated in the cell. But in this lecture it is being said many a times that the DNA is degraded. which is completely incorrect.
@biologybasicsbyn.k.c.1744
6 жыл бұрын
Dr. Sanjeev Pandey, he is actually confused, he think he has done all the learning, nothing is left.
@lolohsn2515
6 жыл бұрын
mRNA is degraded* not the DNA
@jayeshbodkhe6156
5 жыл бұрын
@@biologybasicsbyn.k.c.1744 better you watch your channel only 2 video with 1 subscriber lol NKC
@shanzaynafees279
2 жыл бұрын
Laaaik log 😲😲,,,,, hmain kB itna knowledge ho gaya 😳😳
Shomo sir. you are a best teacher of science and your method are best but pls you are use hindi language
correction plz: mRNA is degraded instead of DNA
Tq soo much sir
@shomusbiologyofficial
5 жыл бұрын
You're welcome
Good! From Mexico! Thx a lot :)
Sir pls make a separate video on VIGS ......
@merik6131
Жыл бұрын
Yes pls sir .will be grateful
Sir I can not understand how can we find out this is my gene of interest
@red8527
3 жыл бұрын
If you disrupt a gene (by inserting a transgene), then observe what was the effect on the phenotype, you'll identify the gene's function. How to identify the gene you've disrupted? Simple. Use a probe for the transgene you inserted & isolate the segment. The sequences on both sides of the transgene will be the gene disrupted. This is known as gene tagging.
Plz sir make a video on epigenetics....coz there is no any kind of good lecture here on youtube so far.. For students
@shomusbiologyofficial
5 жыл бұрын
Okay. I will consider that
Nice
@shomusbiologyofficial
4 жыл бұрын
You're welcome
Thanksss sir.... Always....
@shomusbiologyofficial
4 жыл бұрын
You're welcome. Glad to hear that you're getting benefit from my lectures
@botanicalconcept5889
4 жыл бұрын
Yes...You are the inspiration of life.... Thanksss sir... Always....
Please can you give me the reference paper of this
@shomusbiologyofficial
4 жыл бұрын
Sorry didn't recall
Sir can you kindly make a full video on ( mechanism of gene silencing in eukaryotes )
@shomusbiologyofficial
Жыл бұрын
Okay
@asadkhn2003
Жыл бұрын
Thank u so much sir
@asadkhn2003
Жыл бұрын
I have presentation on this I so confused how to make it. I always watch your videos and make my assignments from it. U are the one who always help me thank u so much❤
Sir please can you make a vedio on virus induced gene silencing
@shomusbiologyofficial
3 жыл бұрын
Okay
Nyc
@nishantupadhyay01
3 жыл бұрын
Patanjali Rice, Very NYC
❤❤
@shomusbiologyofficial
5 ай бұрын
Thank you
🙏🙏🙏🙏🙏🙏🙏🙏
Somu da aktu jore bolun please 🙂
@shomusbiologyofficial
2 жыл бұрын
It's the fault of the mic. I always speak loud
Sir Hindi me video banao
@shomusbiologyofficial
4 жыл бұрын
Sorry
@suneelkumar-bb5mt
4 жыл бұрын
OK sir
Plesae focus on the topic, additional informations are too much added, length of vedio also irritated. Points might be focused as Definition : Gene silencing Brief history of the topic Procedure Applications Current aspects.
@shomusbiologyofficial
6 жыл бұрын
+Basic Biology Brilliants sorry friend. I don't make robotic videos
বেশি ইংরেজি ঝেড়ে নিজের মাতৃভাষায় বল বাবুমশাই।
@shomusbiologyofficial
Ай бұрын
Gadha date ta dekh. Tor social media te jonmo o hoyni tokhon.
This is the highest foolishness.... Man as ever done. Shutting off the Gods gene.