Everything You Need to Know About the First Pig-Human Heart Transplant

Cardiologist examines the science, the history, and the unexpected ethical considerations as we enter a brave new world of XENOTRANSPLANTATION.
References:
Xenotransplantation review (open access) - www.ahajournals.org/doi/10.11...
Heart xenotransplantation (sci hub link) - sci-hub.st/10.1097/MOT.000000...
Comparison of human and pig hearts - www.ncbi.nlm.nih.gov/pmc/arti...
Human-mouse glial chimeras - www.jneurosci.org/content/34/...
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Пікірлер: 1 500

  • @MedlifeCrisis
    @MedlifeCrisis2 жыл бұрын

    There's yet another unusual angle on this, which I learnt after recording but didn't include as I thought it would distract from a general discussion. The recipient, David Bennett, committed a heinous crime in the past. His victim's sister made an emotional statement saying how upset she is that he (Bennett) has been given a "second chance" when her brother wasn't. But others have said he seems like an ideal candidate to test out new surgery on. Medical professionals should base decisions to treat solely on medical history, and that's what has been done. Whether you think it's a fly in the oinkment or hogwash, it's certainly food for thought.

  • @Wulfryk

    @Wulfryk

    2 жыл бұрын

    would be an interesting topic for a different video. with a broad take on multiple ethical dilemmas the medical field is facing. granted perhaps it'd be a good idea to do it as a discussion format with other professionals/guests

  • @doctorpanigrahi9975

    @doctorpanigrahi9975

    2 жыл бұрын

    Is it okay to give Homeopathy instead of Heart transplant?

  • @Wyattporter

    @Wyattporter

    2 жыл бұрын

    Personally, I would find it unconscionable to suggest that because someone previously committed a crime, then they should be denied the best possible medical care. Reading up on the situation, apparently it is the case that hospitals may lower an individual’s priority for transplants if they have a history of substance abuse, which I find disgusting and amoral! Our medical system is far from perfect in the USA, but to withhold the highest standard of care from criminals would be to worsen the situation further.

  • @BigMamaDaveX

    @BigMamaDaveX

    2 жыл бұрын

    @@Wyattporter Depends on the crime, I suppose... But that's another long debate on ethics. 😉

  • @Blowfeld20k

    @Blowfeld20k

    2 жыл бұрын

    bruvah!!!! am NOT happy!!! ...... Think you owe me an new monitor , since mine is now covered in lukewarm Tea. :P

  • @KharmaMedic
    @KharmaMedic2 жыл бұрын

    You are genuinely the best medical education channel on KZread. Highly informative videos with the best jokes I can't help but enjoy every second. Great stuff 🙌🏻

  • @MedlifeCrisis

    @MedlifeCrisis

    2 жыл бұрын

    ah thanks mate. You’re crushing it too, almost finished medical school! I actually thought of tweeting this video with “this one is a BANGER” 😂

  • @Aphelia.

    @Aphelia.

    2 жыл бұрын

    Two people that made me choose medicine interacting

  • @abchaplin

    @abchaplin

    2 жыл бұрын

    "Medlife Crisis: come for the information about medical science and the healing arts; stay for the egregious puns." :D

  • @Wayne-O-5169

    @Wayne-O-5169

    2 жыл бұрын

    @@MedlifeCrisis If you had actually used the phrase “this one is a BANGER” you would undoubtedly have gotten “mashed” in the comments! But, not to worry, your loyal fans would “pig” you up afterward.

  • @YTChannel344

    @YTChannel344

    2 жыл бұрын

    @@MedlifeCrisis The patient that received the pig-heart xeno transplant had died 2 months later. Most likely some sort of issue regarding bodies rejection, proper gene-editing and a few more drugs might be required to stabilize the patient's condition. Organ rejection is still a huge issue that needs to be solved...

  • @callmeray7705
    @callmeray77052 жыл бұрын

    This video is great for quotes; the pig is sus, dystopian novels are the blueprints for humanity, big farmer, it's all so good!

  • @nefariousyawn

    @nefariousyawn

    2 жыл бұрын

    He's a linguistic wizard!

  • @coalyboi7939

    @coalyboi7939

    2 жыл бұрын

    Big farmer was too good

  • @Harmonikdiskorde

    @Harmonikdiskorde

    2 жыл бұрын

    'big farmer' is excellent.

  • @OtterSou

    @OtterSou

    2 жыл бұрын

    my favorite is "is bacon now the cause and the cure for heart disease?"

  • @vigilantcosmicpenguin8721

    @vigilantcosmicpenguin8721

    2 жыл бұрын

    It appears there are more possible pig puns than previously purported.

  • @pjk9225
    @pjk92252 жыл бұрын

    My older brother died when he was only a few months old, and my mother opted to donate his organs. I know it must have been SO hard for her in the moment, and I'm so proud that her and my dad opted for the transplants. Our family's tragedy meant that another child could see, another could breath, and others got every other transplantable organ available (hopefully). I look forward to the day where we can just 3d print organs we need, but until then, I'm glad that one of the deepest tragedies has the smallest of silver linings

  • @Czenda24

    @Czenda24

    2 жыл бұрын

    Don't want to be cynical but I'd think the organ donation was the least hard thing about that moment for your mother.

  • @WhoAmI2YouNow

    @WhoAmI2YouNow

    2 жыл бұрын

    @@Czenda24 Uhmmm.. well I think it would be VERY hard, because if my husband dies, I think I would want to be selfish and 'keep him' for myself. So I can say goodbye to his body a couple days. When you agree to donation, you don't have this goodbye..

  • @AlexTunstall

    @AlexTunstall

    2 жыл бұрын

    @@WhoAmI2YouNow but you do get that chance though, just because they've taken organs doesn't mean the outside of the body looks any different

  • @RuthEdelstein

    @RuthEdelstein

    2 жыл бұрын

    @@WhoAmI2YouNow not wanting your loved one cut up and body parts sent wherever is not selfish.

  • @ophelia.artaud

    @ophelia.artaud

    2 жыл бұрын

    @@RuthEdelstein would you.. get an autopsy on a loved one who died under mysterious circumstances? They'll be getting sliced up and probably parts of them extracted so yeah that's obviously not the issue. Most people nowadays I know who've died end up getting cremated anyway if you'd burn the whole thing why would you care if organs were removed first

  • @thysonsacclaim
    @thysonsacclaim2 жыл бұрын

    @ 22:52 - To touch off this point: Quite a lot of experts of the cancer Jobs had believe he essentially caused his own death. He postponed surgery by 9 months to look in to natural cures. By the time he consented, the cancer went from needing a discrete tumor removal to an entire Whipple Procedure. His cancer is one of the ones Pancreatic Cancer patients would hope to have. It's immensely treatable when caught early like his was.

  • @nexaentertainment2764

    @nexaentertainment2764

    2 жыл бұрын

    In the spirit of interesting discussion, I've actually read that how much he decreased his odds of survival is surprisingly controversial. I'm just quoting Jobs's wikipedia article, but here's an excerpt "David Gorski [an oncologist and professor] wrote that "it's impossible to know whether and by how much he might have decreased his chances of surviving his cancer through his flirtation with woo. My best guess was that Jobs probably only modestly decreased his chances of survival, if that."" I want to be clear I'm not defending his actions, or even endorsing them. I'm firmly in the camp that believes Jobs only hurt his survival odds and did something that was blindingly obtuse and not in line with the medical consensus. But I see this story repeated with such absolute resolution very frequently, that I was surprised to learn that it's actually not entirely so black and white. While he did most certainly ignore medical advice and very likely hurt his odds of survival, there is some question as to whether or not he would've survived anyway. I find that fascinating, not really for the actual oncology/Jobs life, but because of how the story is often treated in media. It's painted as if Jobs had a 100% chance of survival and simply made a stupid hippy anti-intellectual choice and it cost him his life (to be perfectly clear, that is very possible, if not even very likely). You don't really hear any else. In complete fairness though, even on his wiki page the next quote/excerpt is from a conflicting opinion: "Barrie R. Cassileth, [...] on the other hand, said, "Jobs's faith in alternative medicine likely cost him his life.... He had the only kind of pancreatic cancer that is treatable and curable.... He essentially committed suicide."" But I do still find it fascinating, that there's even a divide in opinion, and how it's presented in media. Some doctors that believe he didn't do much harm, and others that believe he threw his life away. I am in no way qualified to really have a medical opinion either way (only that I generally agree that alternative medicine would just be called medicine if it worked).

  • @paulcooper8818
    @paulcooper88182 жыл бұрын

    Imagine pig heart recipients waking up after a successful operation and squealing with delight.

  • @srivatsajoshi4028
    @srivatsajoshi40282 жыл бұрын

    "Is bacon now the cause and the cure for heart disease?" I have been audibly laughing for a whole minute now. That was awesome.

  • @lukey666lukey

    @lukey666lukey

    2 жыл бұрын

    it was a good one, I also loved the heart dependant organ bit too

  • @scootergirl3662

    @scootergirl3662

    Жыл бұрын

    Im mean Im still gonna eat bacon, im just gonna think of this and laugh while eating bacon hence adding yet another benefit

  • @sadfacereview3591

    @sadfacereview3591

    9 ай бұрын

    @@scootergirl3662 he died in 2022... David Bennett, 57, died Tuesday at the University of Maryland Medical Center. Doctors didn’t give an exact cause of death, saying only that his condition had begun deteriorating several days earlier. Bennett's son praised the hospital for offering the last-ditch experiment, saying the family hoped it would help further efforts to end the organ shortage.

  • @iquemedia
    @iquemedia2 жыл бұрын

    I am an American, unfortunate I know, but I am currently blind and am waiting for a cornea transplant The last cornea I received was from a woman who had died in a car accident that morning and unfortunately it rejected currently the doctors at the Houston medical center are saying that my eyes can be saved and are ready for a transplant The insurance is saying that they aren't going to pay for any of it and that any old cornea will do if I had the option to take a cornea from a pig I definitely would and not only that I wouldn't have to wait for someone to die of covid to receive new corneas on top of all this, my mother was diagnosed with cardiomyopathy back in the mid 2000s due to her condition she is ineligible for a heart transplant right now, but if we would be able to give her a pig's heart it would be life-changing and a life-saving for her this video has affected me in a way that I'm not sure is expressable in words Dr Francis thank you for doing what you do you were an inspiration to my KZread channel and an inspiration for why I have wanted to become a cardiologist since I was 14 before coronavirus I was applying to medical school and my disability has kind of thrown a wrench in becoming an MD I apologize for any errors in this comment, like I said I am blind and I am using text to speech My mother and I are fighters and we will never give up and to anyone who is reading this who is going through a similar situation I encourage you to keep fighting I know that it is hard but there is a light at the end of the tunnel

  • @drtasnia

    @drtasnia

    2 жыл бұрын

    Best of luck to you. An ironically very well written comment ;) I hope you can see again very soon. X

  • @Obomber

    @Obomber

    2 жыл бұрын

    I wish I was blind. You can have my cornea.

  • @khazermashkes2316

    @khazermashkes2316

    2 жыл бұрын

    You deserve better than discount corneas. If there is any possible way to appeal the insurance company’s decision or get the local news to shame them please do not hesitate to do so.

  • @iquemedia

    @iquemedia

    2 жыл бұрын

    @@khazermashkes2316 thanks for the support! once we told the insurance we have a lawyer they started paying for things real quick, sad lol but it's paid I'll be posting a video explaining my story soon :)

  • @khazermashkes2316

    @khazermashkes2316

    Жыл бұрын

    @@iquemedia I am glad that the insurance company did their job, but angry that you needed a lawyer. Please let us know once you have posted the video about it!

  • @polgabaldon
    @polgabaldon2 жыл бұрын

    What an utter gem of a video Rohin! Enthralling by the storytelling and facts, and I laughed out loud many times, both because of the editing and the witty jokes. Thanks! ❤️

  • @alp1738

    @alp1738

    2 жыл бұрын

    Is bacon now the cause and the cure for heart disease 😂. Yeah this video is absolute gold!

  • @thePronto

    @thePronto

    2 жыл бұрын

    I wonder how many Americans get Rohin's humor. I (attempt to) crack similar jokes with American colleagues and all I get are blank stares. But I come to this channel and roar with laughter. It's kinda like coming home, but without the tax liability. (See what I mean?)

  • @taviss2775

    @taviss2775

    2 жыл бұрын

    Fantastic video! Your humour is on point here and I loved it. 10/10!

  • @serendipitouspareidolia2220

    @serendipitouspareidolia2220

    2 жыл бұрын

    Has he made any jokes about the idea of 'heritability' as postulated by Gary Schwartz, i.e. in this case acquiring more pig-like behaviour?

  • @Subfightr
    @Subfightr2 жыл бұрын

    I love this man. He always does an amazing job of explaining things, and combats pseudoscience. For him to take his precious time to make complex videos like this to help educate people, really is quite incredible. Thank you good sir.

  • @samrusoff

    @samrusoff

    2 жыл бұрын

    Genuinely impressed by how fun the educational videos are via humor and editing too. I keep rewatching the organ tier list video, it's fantastic

  • @nikkitronic80
    @nikkitronic802 жыл бұрын

    This subject is so very interesting to me. I am a cardiac patient. Three years ago I had my aortic valve replaced with a porcine valve. I thanked my little piggy every day for my life. I loved telling people my story and of my pig part. I knew that my little piggy would wear out some day and have to be replaced. It happened pretty fast as I am young (41) and very active. Feb 4th 2022 I had to have piggy replaced, this time I got a mechanical valve. It’s called a Top Hat (sounds fancy, ya?) and a bovine patch had to be placed on my aortic root due to an abscess we didn’t know was there. So now I have a cow part in me (thanks my bovine friend). Recovery from this second surgery was long and very hard. I’m just now feeling myself again. I just found out that unfortunately I might be looking at another surgery because in the 11 weeks since surgery I’ve grown much scar tissue around my valve which is impeding the flow of blood through the valve which makes it hard for me to catch my breath under much exertion. I’ll be seeing a specialist cardio surgeon at UW next week to find out what can be done for me. It’s pretty scary. I’m so young and have so much I still want to do in life. The thought of not being here to reach those goals or being here for my boys is just terrifying. But I have much faith in the medical professionals who look after me and look up to a higher power as well. It’s all I can do (besides taking my prescribed meds and doing my best every day to be as healthy as possible through exercise and heathy eating). I often think of all the doctors and patients and research and experiments and great minds and processes that went on in the past to enable someone like me to even have lifesaving surgery. And I thank them. So ya, that’s my story in a nutshell. Videos and topics such as this are endlessly fascinating to me ever since my heart troubles began. I quite enjoy telling my story involving my heart. Even in KZread comments. So thanks for reading and I hope you have a great day! 🐷 ❤️

  • @fairenough7984

    @fairenough7984

    Жыл бұрын

    Conversely, my father had an aortic valve replace with a pig valve when he was 60. He was also told it would likely need replaced at some point, however, it functioned well for 20 years and may have worked longer but he was diagnosed with lymphoma at age 80 and passed away. The pig valve was never an issue, and it was speculated that maybe because he tended to have low blood pressure, which may have not been as taxing on the valve itself. I wish you continued good health and a blessed new year.

  • @ksharma103
    @ksharma1032 жыл бұрын

    BIG FARMER- nearly spilled my coffee there. The media references. The flawless timing. The witty sarcasm and clever puns. Every single joke was absolutely pristine *chef's kiss* The content, of course, just as engaging! Also, bioethics is a reaalllyy messy arena- yet, you've managed to include it in a rather immaculate manner here. Surgical caps off!

  • @BigMamaDaveX
    @BigMamaDaveX2 жыл бұрын

    The closing lines of Orwell's "Animal Farm" at the end are chilling. Considerable food for thought.

  • @andrewharrison8436

    @andrewharrison8436

    2 жыл бұрын

    Glad you made this comment. Remember Orwell wrote his books as warnings not as instruction manuals. (Not everyone got the memo saying this).

  • @sandwich2473
    @sandwich24732 жыл бұрын

    Goodness me, this is definitely up there in the greatest videos you've ever made. Trotterly captivating from start to finish, highly informative and very entertaining to boot. Well done indeed 👀

  • @zyansheep

    @zyansheep

    2 жыл бұрын

    THE PIG DO BE LOOKIN A BIT SUS THO

  • @aesbj9228

    @aesbj9228

    2 жыл бұрын

    I express my agreement

  • @MazHem

    @MazHem

    2 жыл бұрын

    oh hey sandwich it's me maz from twitter

  • @sandwich2473

    @sandwich2473

    2 жыл бұрын

    @@MazHem :o hello o/

  • @brownianmotion7747
    @brownianmotion77472 жыл бұрын

    Waiting for the video that will discuss how it failed.

  • @SilveniumTheDrifter

    @SilveniumTheDrifter

    2 жыл бұрын

    Agreed

  • @markhitchcock7380
    @markhitchcock73802 жыл бұрын

    This video encapsulates everything I love about your channel. Stupid jokes, interesting medical topics, and thought provoking philosophy.

  • @SofaKingShit
    @SofaKingShit2 жыл бұрын

    I saw on a msm news broadcast that apparently the guy who got the transplant had stabbed a fellow in a bar 30 years ago and put the unfortunate victim in a wheelchair which raised questions about his deservedness to get the operation. If you take that sort moralism to it's logical conclusion then hospital emergency rooms would have to wait to for an investigation to determine if a road accident victim was at fault before any treatment was offered. Personally I wish the guy well.

  • @IndisSongs

    @IndisSongs

    2 жыл бұрын

    Yes!

  • @PedroRodriguez-kg4bq

    @PedroRodriguez-kg4bq

    2 жыл бұрын

    Wouldn’t say I wish him well :D But I’m not his doctor who, as you say, won’t do a background check and is simply trying to treat the body.

  • @Ole_Rasmussen

    @Ole_Rasmussen

    2 жыл бұрын

    People who stab others do not deserve life.

  • @teteteteta2548

    @teteteteta2548

    2 жыл бұрын

    @@Ole_Rasmussen unless you agree with the,, in which case you protect them

  • @Wyattporter

    @Wyattporter

    2 жыл бұрын

    @@Ole_Rasmussen heavily disagree. Doctors and hospitals need to provide the best care possible, regardless of the patient’s history.

  • @ivanjednobiegowiec7656
    @ivanjednobiegowiec76562 жыл бұрын

    Like they are saying in my country: "bawiąc, uczyć", that I would somewhat crudely translate into: "educate through fun". You, Good Sir, are the prime and stellar example of that philosophy, me thinks. I can feel echoes of Hugh Laurie, Stephen Fry and John Cleese in your comedic chops. Classic British Humour with very, very serious undertones, if you are quick and smart enough to see it. Chapeau Bas!!! Cheers! I.

  • @WhatsSoGreatAboutThat
    @WhatsSoGreatAboutThat2 жыл бұрын

    I'm glad other people remember Pig Heart Boy because whenever I hear anything about heart transplants all I can think is PIG HEART BOY! I do not remember it looking so much like a bad PSA though lol

  • @WhatsSoGreatAboutThat

    @WhatsSoGreatAboutThat

    2 жыл бұрын

    Another thing I didn't remember, they gave Babe a little wig?! wtf

  • @estebanchicas6340

    @estebanchicas6340

    2 жыл бұрын

    Omg I've loved your videos for like 4 years!!!

  • @wavicle42
    @wavicle422 жыл бұрын

    I met an American guy at a comicon a couple of years ago whose job it was to prepare bodies for subsequent medical use (or something like that). He told me that the silver lining of the opioid crisis in the US was that the heart and lung transplant waiting lists were super short because if someone died from an opioid overdose, those organs were still good. Just wondering if you have any thoughts or further info on this!

  • @pattheplanter

    @pattheplanter

    2 жыл бұрын

    I believe it was found that adding opioids preserves organs for longer while awaiting transplant. So some are pre-cured like ham.

  • @juliusfinkas

    @juliusfinkas

    2 жыл бұрын

    Wow. I feel like we can almost always give something positive in any situation if we just look hard enough. Still pretty cool.

  • @mamacito1795

    @mamacito1795

    2 жыл бұрын

    @@juliusfinkas I mean sure that's one way to look at it, but it's still hella grim

  • @villevalste1888

    @villevalste1888

    2 жыл бұрын

    @@mamacito1795 How so?

  • @juliusfinkas

    @juliusfinkas

    2 жыл бұрын

    @@mamacito1795 i agree, i just find it fascinating that we can take a bad situation and still find positives. I don't think it could ever justify it being okay.

  • @rambam23
    @rambam232 жыл бұрын

    “Treif” is specifically referring to forbidden foods: it literally means “torn.” “Asur” means forbidden more generally and so would be correct in this instance. In terms of the ethics, I’m torn. I’m a vegetarian and I think that we shouldn’t be exploiting animals for any purpose, but it’s hard to condemn the potential use of a few thousand pigs to save human lives when hundreds of millions are killed for culinary enjoyment.

  • @BigMamaDaveX

    @BigMamaDaveX

    2 жыл бұрын

    🔎 I never knew that "Treif" meant "torn"; I'd always thought it to be synonymous with "Dreck" meaning "dirt". 🙏 Thanks for clearing that up. (I appreciate learning new things... Keeps my brain doing pushups!) 😉

  • @nicka3697

    @nicka3697

    2 жыл бұрын

    I can see why you're Torn it's hard to be Asur as you would like to be on such complex matters.

  • @brianb.6356

    @brianb.6356

    2 жыл бұрын

    Also: treif is pronounced "TRAYF". One syllable, rhymes with "safe".

  • @shouko4218

    @shouko4218

    2 жыл бұрын

    @@BigMamaDaveX didn’t know there are words in the English language that have kept their German form because “Dreck” is literally dirt in German :D

  • @surealivro6242

    @surealivro6242

    2 жыл бұрын

    @@shouko4218 Yiddish

  • @Jonathan-zf6ho
    @Jonathan-zf6ho2 жыл бұрын

    just ask david cameron. fuck me (not the pig) that was an amazing joke

  • @universeofdiscovery
    @universeofdiscovery2 жыл бұрын

    As medicine advances with science and technology, we are finding more ways to keep people alive for longer. While keeping someone alive longer is a great thing, you would also have to consider there quality of life. Also as you mentioned ethics is something we can not forget. Great explanation. 👍

  • @silverdragon612
    @silverdragon6122 жыл бұрын

    Thank you for talking about Jewish and Muslim necessity to save life over all else. It's felt weirdly pointed and uncomfortable with how many people have been directly asking about this to only us. There's this stupid trope of Jews in media (specifically medical shows), refusing treatments because it's not "Kosher", and I feel like this over-obsession on our opinion of this transplant partially comes from that. Idk its weird; I was so worried watching this that you were gonna be like "another issue is whether Jews and Muslims will take this treatment and so on" but I was really really pleased, just another reason I love this channel!

  • @krishg8647
    @krishg86472 жыл бұрын

    19:40 "The pig is sus" Always love these memes from an informative channel! Thanks for the laughs 🤣

  • @oskarstaudte

    @oskarstaudte

    2 жыл бұрын

    I blasted out laughing

  • @ayrendraganas8686

    @ayrendraganas8686

    2 жыл бұрын

    timestamp should be 19:40

  • @krishg8647

    @krishg8647

    2 жыл бұрын

    @@ayrendraganas8686 updated, thanks!

  • @krishg8647

    @krishg8647

    2 жыл бұрын

    @@oskarstaudte me too 🤣🤣

  • @weissergspritzter
    @weissergspritzter2 жыл бұрын

    One of your best videos, especially the part about ethics. Fascinating times ahead.

  • @DuffyElmer
    @DuffyElmer2 жыл бұрын

    "The Washington Post reported that Bennett's son, David Bennett Jnr, said that hospitals had refused to add his father to the wait list because he previously failed to follow doctor's orders, take his medication regularly, and attend follow-up visits." Perfect candidate for a pig heart tbh, proven treatments should go where they'll be the most likely to do good, and that means patients who will take care of the donor organs they've been gifted

  • @robmalek3731
    @robmalek37312 жыл бұрын

    "All animals are equal, but some animals are more equal than others." -George Orwell, Animal Farm Great video! A good deal creepier than I expected it to be but that just goes to show how I saw this matter with a mindset that was far too uninvolved.

  • @evannibbe9375

    @evannibbe9375

    2 жыл бұрын

    Animals are not equal

  • @AdrianParsons
    @AdrianParsons2 жыл бұрын

    The first 27 seconds of this video is all that it needed. Just perfection. Everything else is a bonus.

  • @AdrianParsons

    @AdrianParsons

    2 жыл бұрын

    The Loony Toons outro is *inspired*.

  • @levismith5169
    @levismith51692 жыл бұрын

    As someone who’s goal in life is to become a doctor the rapid advance of medical technology is so incredibly exciting

  • @revolvency

    @revolvency

    2 жыл бұрын

    Good luck 👍🏻

  • @levismith5169

    @levismith5169

    2 жыл бұрын

    @@AlanTheBeast100 idunno that question seems patronizing to me…

  • @levismith5169

    @levismith5169

    2 жыл бұрын

    @@revolvency thank ya!

  • @ratusbagus

    @ratusbagus

    2 жыл бұрын

    @@levismith5169 guess you don't need a humourectomy then.

  • @medullaoblongata1616

    @medullaoblongata1616

    2 жыл бұрын

    As a medical student myself, I am rooting for you!

  • @sopyleecrypt6899
    @sopyleecrypt68992 жыл бұрын

    As well as Oryx and Crake, the ethics part of your video made me think of Kazuo Ishiguro’s novel Never Let Me Go, in which clones are bred for the use of their organs by the clone’s original when needed. The clones are normal human beings. They are raised knowing their purpose. It’s horrifying.

  • @trytoguess

    @trytoguess

    2 жыл бұрын

    There's also a movie with that premise (The Island). Interestingly, it seems both came out in 2005.

  • @rabbitwho

    @rabbitwho

    2 жыл бұрын

    That's in MICHAEL BAY's film The Island. in Okja the pigs are genetically modified to be tastier, but they are mixed with human DNA as well as the DNA of other species, and they inadvertently make them extra smart as well as extra delicious, so their suffering is magnified. Maybe it's the increased suffering that makes them more delicious. In fairness, pigs are already really loving and intelligent creatures and it already breaks my heart the amount of unnecessary cruelty there is in the meat industry. If you think it's ok to eat them, ok cool, whatever, but why does society also think it's ok to torture them?

  • @rdizzy1

    @rdizzy1

    2 жыл бұрын

    Just do the exact same thing but grow the body without a brain and run the body off of an advanced computer system instead (just runs basic physical functions to keep the body alive), will probably be possible within a few decades when technology and biology inherently end up connecting.

  • @Ruthavecflute

    @Ruthavecflute

    2 жыл бұрын

    @@rdizzy1 I think you underestimate both the complexety of the brain's job and the difficulty in growing a body without a brain.

  • @rdizzy1

    @rdizzy1

    2 жыл бұрын

    @@Ruthavecflute No I don't, I over estimate the technological advances of future society, considering how technological advances usually compounds the speed at which it advances.

  • @abcdisaster
    @abcdisaster2 жыл бұрын

    I hope an update is coming soon given current events

  • @rob7166
    @rob71662 жыл бұрын

    I think Singer's ideas about speciesism were explained incorrectly here. For example, Singer would have no problem saying that humans are superior to worms because we are more intelligent, more capable of complex emotions, and so on. The gap between us and pigs in those areas is much smaller, so it makes sense to treat pigs with much more respect (while still not valuing a pig life as much as a human life). Speciesism is when we ignore an animal's intelligence, capacity for emotions, etc. and treat them as without rights or value *just because* they are not human.

  • @paulgoogol2652

    @paulgoogol2652

    2 жыл бұрын

    This is just a great example of lifeism. There is no reason to give privilege to living beings based on arbitrary traits.

  • @merrymachiavelli2041

    @merrymachiavelli2041

    2 жыл бұрын

    @@paulgoogol2652 So why do we value human life? Is murder okay? There is no way to provide a coherent, secular argument for the value of human life that doesn't imply we should value animal life to differing degrees as well.

  • @josiahferguson6194

    @josiahferguson6194

    2 жыл бұрын

    While the consideration of intelligence does solve some ethical problems it also creates new dilemmas. For example, if we treat animals based on their intelligence, by what justification can we oppose treating humans who are less intelligent differently? How do we measure intelligence? etc.

  • @Trirosmos

    @Trirosmos

    2 жыл бұрын

    @@merrymachiavelli2041 We came to value human life and have empathy for one another because it was hugely advantageous, evolutionarily. I don't think there's any rational explanation for why we ought to value human life inherently, or any other kind of life for that matter, and I think that's okay.

  • @sita1267

    @sita1267

    2 жыл бұрын

    @@josiahferguson6194 From what I understand, Peter Singer says that the capacity to suffer, rather than intelligence, is what we should use when deciding how to treat them. Source: kzread.info/dash/bejne/k6pmlMWLgbGombQ.html

  • @Mover333
    @Mover3332 жыл бұрын

    I've watched almost all of your videos and this one was your best one ever. The pacing, jokes, education, subject matter all combined artfully. Thank you for the great content. P.S. I still love your vitamin video :)

  • @Biped
    @Biped2 жыл бұрын

    Man you're having way too much fun with your jokes. It's like this whole scientific endeavour was made just to give you a reason for corny comments. I especially liked the outro. Also all books/films/ted-talks seem well worth giving a shot, so thanks in advance for those!

  • @joodsterr

    @joodsterr

    2 жыл бұрын

    His true passion is comedy, clearly!

  • @AeolianMusica
    @AeolianMusica2 жыл бұрын

    The quality of the questions you receive is, at least in part, a reflection of the extremely high quality of your videos. This is superb.

  • @Propulus
    @Propulus2 жыл бұрын

    What a fantastic intro! Your videos somehow keep getting better and better.

  • @raa9558
    @raa95582 жыл бұрын

    Marvelous. Love the depth and discussion.

  • @xoxULTIMATExox
    @xoxULTIMATExox2 жыл бұрын

    Long time viewer, and that is only relevant for the fact that I am sooo happy for your growth and success. Idk man, but your videos are soo entertaining and educational! I can literally just watch your content anytime anywhere. I also love how you focus on the "good and bad" of science and medicine, introducing your viewers to using their own critical thinking and not to go by group-think. You sir got it all and I am here to enjoy it! Much love :)

  • @CelticKnight2004
    @CelticKnight20042 жыл бұрын

    You've nailed it. Human life, is paramount. *if* we can do it to save lives, if we can do it to make lives better, we should research it.

  • @danieljinsun
    @danieljinsun2 жыл бұрын

    the joke output in this video is crazy considering how little time you've have to write this (almost as crazy as a pig heart in a human being)

  • @Friek555
    @Friek5552 жыл бұрын

    This is one of the best videos I have seen in a loooong time. That ending montage is just perfect.

  • @Natasha-tu5qs
    @Natasha-tu5qs2 жыл бұрын

    Great video. And yes you we correct with אסור. The concept is called 'pikuach nefesh', or 'watching over a soul', which basically says that you can ignore almost all of the 'do not' commandments if necessary in order to save a person's life .

  • @georgechrysaphinis6761
    @georgechrysaphinis67612 жыл бұрын

    Brilliant. The content, the delivery and coming so soon after the story came out. Was hooked throughout.

  • @LinusBoman
    @LinusBoman2 жыл бұрын

    13:45 If this person worked in my industry, they'd know that intelligent designers are a myth. 🖍️

  • @JonTullett
    @JonTullett2 жыл бұрын

    This is your best video ever. The info was so accessible and the light-touch ethics thoughtful but not judgmental or condescending, but the puns were even better than usual. I live for the day KZread and medical science combine so I can give three thumbs up at a time.

  • @abdulamin4007
    @abdulamin40072 жыл бұрын

    You're an incredible teacher and create the most engaging videos, I really respect what you do my friend.

  • @John-gw3mj
    @John-gw3mj2 жыл бұрын

    The Cameron joke was a work of art!

  • @NoCokeOnlyIce
    @NoCokeOnlyIce2 жыл бұрын

    I really hate how much you manage to make me chuckle while watching a rather educational video about porcine human heart transplants and the ethics behind it and also make it interesting. Honestly well done.

  • @Jules_Pew
    @Jules_Pew2 жыл бұрын

    I think growing organs from human stem cells is the best way forward. I know it's years away and tinkering with pigs might be easier, but I'd feel happier with more stem cell research.

  • @tissuepaper9962

    @tissuepaper9962

    2 жыл бұрын

    Stem cell research suffers from almost exactly the same problem as nuclear energy. It's a seriously powerful technology that has been dragged through the mud by decades of misinformation and emotional/political disputes.

  • @RuthEdelstein

    @RuthEdelstein

    2 жыл бұрын

    @@tissuepaper9962 I think it's unethical to create human embryos and then take cells from them.

  • @tissuepaper9962

    @tissuepaper9962

    2 жыл бұрын

    @@RuthEdelstein and that is your shortsighted opinion. You're entitled to it.

  • @mathewb7609
    @mathewb76092 жыл бұрын

    You are my muse. I look up to you and admire the high standards you have, for yourself and your content. Keep on being an excellent role model!

  • @thomaswalsh4552
    @thomaswalsh4552 Жыл бұрын

    The first 30 seconds of this video are the best of any KZread video I’ve seen in ages

  • @alexanderivanov646
    @alexanderivanov6462 жыл бұрын

    One of the best videos I have seen in a while. It is fascinating to think about not starting immunosuppressive therapies for pts after a transplant. It goes even further - if you can exchange your heart, next step will be lungs and liver. The only organ not amenable to transplant in the foreseeable future is one’s brain. But who knows who happens next.

  • @maxbramwell.1598
    @maxbramwell.15982 жыл бұрын

    You inform me and make me laugh outloud in the same video. As a comedically scrutinous 21 year old with no background in medecine, i shall hope you realise what an honour that is for me to say that. I love your channel, I love the fact you are an NHS doctor, you communicate health topics in an amazingly understandible way and i think you've got a good grasp on the world. Good work pal!

  • @OlegTheBoss
    @OlegTheBoss2 жыл бұрын

    One of your greatest videos. It's one of those times when I'm sad I don't have anyone with whom I can share it and they can appreciate it.

  • @Omar-jn9zf
    @Omar-jn9zf2 жыл бұрын

    You're the absolute best doctor on KZread. Down to earth doctor with a sky high intelligence. Thank you for the amazing talk.

  • @regular-joe
    @regular-joe2 жыл бұрын

    My brain hurts, and my heart hurts. This video did its job very well. This should be taken seriously. Thank you, Doctor.

  • @1234j
    @1234j2 жыл бұрын

    Excellent video as usual, and you crushed the perfect and appropriate ending! Well done for the appropriate topical insert, who currently needs a topical insert from the country, especially where it hurts.

  • @biancapasca-saturn6269
    @biancapasca-saturn62692 жыл бұрын

    This is the perfect KZread video! Very informative, funny and it leaves you with questions that don't have easy answers. Thank you!

  • @Perl88
    @Perl882 жыл бұрын

    My Dad had a heart transplant in October of last year. After taking out his old heart they estimated that he would have had less than a year to live. Without the precious gift that the donor was willing to make and without the fantastic work of the cardiology team it most probably would have been his last Christmas. Getting more organs to more people in need is definitely worth exploring but using animals must be done the right way. The last thing we need is for it to fall flat on it’s arse as it could be a fantastic way for more people’s lives to be saved.

  • @hiimdandy
    @hiimdandy2 жыл бұрын

    A genuine question: Does the 50% bear DNA go in before or after we add the 50% pig? We gotta get those 3 halves in there somehow

  • @KonradTheWizzard

    @KonradTheWizzard

    2 жыл бұрын

    ...not even talking about squeezing in the 97% chimp DNA! All mammals have a comparatively recent common ancestor about 100 million years ago. So, all mammals have very similar DNA - after all mice are much more similar to humans than they are to plants or birds. If you say pigs and bears each have 50% in common with humans, then there is probably a big overlap of basic mammalian DNA that all 3 species have in common within those 50% - for example the genes that make us grow 4 (instead of 5 or 8) appendages are very similar, but pigs, bears and humans all form different hands and feet, so those genes have differences (not necessarily big ones). We even have a lot of genes in common with plants. That's why we can use many plants as medicine - many substances produced by plants are similar to stuff that our own body produces - it just has a different function in those plants.

  • @FKProds
    @FKProds2 жыл бұрын

    That nonchalant Churchill quote was outrageous. Love it.

  • @ImplodedAtom
    @ImplodedAtom2 жыл бұрын

    The conclusion of that video was brilliant!

  • @robertgarland5012
    @robertgarland50122 жыл бұрын

    This might be the best video yet Rohin! Appreciate the work you put in ❤️

  • @tamara3984
    @tamara39842 жыл бұрын

    Loving the support act.

  • @MollyPrewittWeasley
    @MollyPrewittWeasley2 жыл бұрын

    My grandfather got a pig valve and everytime he ate pig meat he said he was being a cannibal.

  • @akiratoriyama1320
    @akiratoriyama13202 жыл бұрын

    I am following you less than a year. I really enjoy your videos. But this was something else! Thank you!!

  • @Word-Smithy
    @Word-Smithy2 жыл бұрын

    All of your videos are brilliant but, this one ... chef's kiss!! So glad you exist.

  • @Syd448
    @Syd4482 жыл бұрын

    Just came back to rewatch this video, he died March 9, 2022 just two months after his surgery. Great advancements were found though!

  • @Blabla130
    @Blabla1302 жыл бұрын

    Another banger of a video from Dr Francis, veterinarian at large

  • @beepoboopo546
    @beepoboopo5462 жыл бұрын

    This video is amazing! So grateful for you using your time to do these!!

  • @the_0_man
    @the_0_man2 жыл бұрын

    Love your vids man! Love the sarcasm and the jokes and the puns and stuff! The timings are absolute fab

  • @TheMegaMrMe
    @TheMegaMrMe2 жыл бұрын

    You'll probably never read this but you have been a north star of factual comedy these past 2 years. Thank you for the effort you put into these videos. I love to laugh while being fascinated by your field. Although I am not working in the medical field, I love learning more about the human body. The sources you mentioned in the past help me learn even more. This video was a 10/10 (that's an A for the Americans out there). P.S. The exploitation of your children at the beginning of the video for views was also smart. Cute AF :))

  • @magnusbruce4051
    @magnusbruce40512 жыл бұрын

    Yes, yes I do remember Pig Heart Boy. I actually thought that because of that series, the pig heart transplant had been successfully tried before.

  • @Chodor101
    @Chodor1012 жыл бұрын

    I don't know what's better, informative part of your videos, irony or jokes.

  • @recklessroges
    @recklessroges2 жыл бұрын

    I love the proper roasting that you gave this subject, both as a doctor and as a comedian. Bravo.

  • @rdownie1788
    @rdownie17882 жыл бұрын

    Sadly, the recipient died today 9th March 2022

  • @dazraf
    @dazraf2 жыл бұрын

    That was brilliant, thank you! And the jokes, notably Cameron and Andrew, made me laugh out loud!

  • @Mhurilo10
    @Mhurilo102 жыл бұрын

    Your videos are very often better than the papers I read

  • @WobblycogsUk
    @WobblycogsUk2 жыл бұрын

    Brilliant video, one of your best. Easily my favourite channel on KZread. Your videos inspire me to keep my brain active instead of giving in to the daily grind. So many people give in to life and stop thinking.

  • @Zolacolor
    @Zolacolor2 жыл бұрын

    Brilliant video, you really porked out on the pig puns. Very well written.

  • @jeebs1298
    @jeebs12982 жыл бұрын

    This video was especially funny and informative--thank you

  • @COLDMKULTRA
    @COLDMKULTRA2 жыл бұрын

    Love the subtle digs during the wonderful Pigs commentary!

  • @gondwana6303
    @gondwana63032 жыл бұрын

    One of your very best videos!

  • @Richardincancale
    @Richardincancale2 жыл бұрын

    I truly think this is your best video yet! Well done and thank you! [PERV, Sus, Big Farmer references included!!]

  • @thesudaneseprince9675
    @thesudaneseprince96752 жыл бұрын

    This video was extremely interesting and thought-provoking, but also profoundly terrifying - The Percy pig bit at the end was just straight-up disturbing

  • @0.-.0
    @0.-.08 ай бұрын

    Wow! Hard to believe you have less than half a million follows. You're one of the best KZread channels out there. Humourous and educational, not to mention interesting and charismatic. You're so awesome!

  • @lukey666lukey
    @lukey666lukey2 жыл бұрын

    amazing video and that ending, just perfect. chefs kiss

  • @handswaps6163
    @handswaps61632 жыл бұрын

    My mum’s a journalist and actually reported on the 1997 Indian transplant attempt at the time - she travelled from Hong Kong to be on the scene, and I think she was struck by how insanitary and improvised it seemed. She wasn’t surprised that the transplant was a failure. Thanks for the video, really interesting!

  • @starlight8554
    @starlight85542 жыл бұрын

    I’m a vegetarian but I’m also a medical intern so I’m a bit torn on this. For me saving a patient’s life will always be paramount, obviously. This makes the already large grey area when it comes to medical ethics even greyer. This is all very very interesting stuff though. Reminds me of my medical ethics classes in third year.

  • @vdinh143

    @vdinh143

    2 жыл бұрын

    I find it a trivial problem from the perspective of a consequentialist. However many years the animal suffers in its upbringing (if it even experiences suffering depending on our rearing quality) can simply be compared to the number of years the human would spend in pain or, worse, death.

  • @starlight8554

    @starlight8554

    2 жыл бұрын

    @@jackoh991 I’m a vegetarian, so I still eat some animal products. I’m more against the killing part than anything else. I’m an intern and I haven’t personally prescribed anything yet.

  • @grmpEqweer

    @grmpEqweer

    2 жыл бұрын

    @@starlight8554 One of the medicines keeping me alive took _thousands_ of rats to invent. I take a lot of different meds. 😬 I'm otherwise a vegan, mainly for health reasons.

  • @OrWhatWeHave

    @OrWhatWeHave

    2 жыл бұрын

    @@starlight8554 mice/rats are typically euthanized at the end of a pharmaceutical experiment, especially considering many experiments require giving them awful diseases to start with. Animal testing is killing.

  • @knufyeinundzwanzig2004

    @knufyeinundzwanzig2004

    2 жыл бұрын

    @@starlight8554 Why are you more against killing than torture?

  • @idkbruh299
    @idkbruh2992 жыл бұрын

    Man I don't know how we are getting this content for free.

  • @myce-liam
    @myce-liam2 жыл бұрын

    Loving the jabs at David Cameron and Prince Andrew. Also a really informative video, thanks for putting the time into this.

  • @ForeignManinaForeignLand
    @ForeignManinaForeignLand2 жыл бұрын

    Lawd we putting pig hearts in ppl? What a time to be alive!

  • @Land89

    @Land89

    2 жыл бұрын

    I don't think the pig would agree :D

  • @ForeignManinaForeignLand

    @ForeignManinaForeignLand

    2 жыл бұрын

    @@Land89 🤣 okay, you should be the one with the YT channel. Not me

  • @TASHITE

    @TASHITE

    2 жыл бұрын

    A di same ting ppl we'n seh when de'n first start with electricity. But look at the world now. The future is unlimited replacement organs.

  • @zyansheep

    @zyansheep

    2 жыл бұрын

    Two Minute Papers reference?

  • @pedroff_1

    @pedroff_1

    2 жыл бұрын

    @@zyansheep Just wait to see how it'll be two pigs down the line

  • @ArtixBlader
    @ArtixBlader2 жыл бұрын

    Physician associate in the UK here! Love your wonderful ability to entwine education and humour. We are taught as healthcare professionals not to be judgemental and yet it occupies one of the four pillars of ethics. Many patients awaiting livers will miss their opportunity for a transplant without evidence of sobriety, but this seemingly endless supply (although I'll hold my breath for the QALY analysis) would potentially avoid these judgement calls as well as the grey cases as you mentioned. Again wonderfully interesting, keep up the great work!

  • @notmyname327
    @notmyname3272 жыл бұрын

    I'm so glad I found your channel through Tom Scott's video. "The pig is sus", "big farmer", I need to watch all your videos now. Also the subject is really interesting and I found you touched on all the angles I was intrigued by, and many others I hadn't even thought about. Really good stuff.

  • @Kombivar
    @Kombivar2 жыл бұрын

    The ending line from the Animal Farm gave me shivers - Awesome stuff, as always!

  • @surealivro6242
    @surealivro62422 жыл бұрын

    10/10 video

  • @LivingNexus
    @LivingNexus2 жыл бұрын

    Have you considered doing a video on neurocardiology? I would love to see you have a conversation about it with a neuroscientist, since I haven't seen that many people talking about it in detail, even though research on the subject has been around since the 1970s. It also directly relates to organ transplants in that a lot of the time, it seems the heart's own internal immune system takes a very long time to reactivate after transplantation, and it never reaches pre-transplantation levels of activation. It would be really interesting to learn how the heart's neural wiring works and how that affects their nervous system as a whole from someone who can understand the research.

  • @erikawhelan4673
    @erikawhelan46732 жыл бұрын

    Perfect outro! Very interesting subject and as usual a stimulating discussion. Thank you.

  • @samtravis4822
    @samtravis48222 жыл бұрын

    What a brilliant, thoughtful and well made video. Keep up the great work!