Ep. 12: What's Worse-Carbs or Seed Oils? Understanding a Hi-PUFA Diet-w/ Brian Kerley & Matt Quinn

Ғылым және технология

Introduction
We’re trying something a bit different today. Dr. Brian Kerley and I have found a victim, Matt Quinn. Matt’s a smart guy but he’s not as immersed in these topics as we are, and so he’s going to play our straight man, the every-day guy who can hopefully come to easily-digested conclusions about the papers we discuss.
In our inaugural episode we discuss “Brief Episode of STZ-Induced Hyperglycemia Produces Cardiac Abnormalities in Rats Fed a Diet Rich in N-6 PUFA”.
Ghosh, S., Qi, D., An, D., Pulinilkunnil, T., Abrahani, A., Kuo, K.-H., Wambolt, R. B., Allard, M., Innis, S. M., & Rodrigues, B. (2004). Brief Episode of STZ-Induced Hyperglycemia Produces Cardiac Abnormalities in Rats Fed a Diet Rich in N-6 Pufa. American Journal of Physiology. Heart and Circulatory Physiology, 287(6), H2518-2527. doi.org/10.1152/ajpheart.0048...
Guest info
Matt Quinn
/ mqsley
www.mquinn.online/
Biography:
TL;DR Here's what I am working on:
I run Rebel - a fund that buys distressed SAAS and turns it around - if you want to support share our apps here
I'm in the very early stages of building/buying a regenerative farm. Our food system is beyond broken. Our healthcare system doesn't heal people. If you're interested in the thoughts behind this read this
I've built companies, bought companies and burned companies - if you're looking for pro bono advice or mentoring - tweet/DM me here
In my day job I run a product consulting team at Tanzu Labs - if you have deep pockets and need a team to teach you how to build great software that users love - connect with me here
I have failed at so so so many things - read about them here
www.mquinn.online/
_______________________________________
Co-host
Dr. Brian Kerley
www.seedoilrebellion.com/
/ seedoildsrspctr
Looking to fix your diet by getting rid of seed oils?
Check out the Seedy app!
www.seedyapp.com/
Tucker Goodrich
Substack: tuckergoodrich.substack.com/
Twitter: / tuckergoodrich
KZread: / tuckergoodrich0
Apple podcast: podcasts.apple.com/us/podcast...
Spotify podcast: open.spotify.com/show/7wVZ3Tn...
Podcast: sites.libsyn.com/408758
Blog (deprecated, but still a lot there!): yelling-stop.blogspot.com/
_______________________________________
Show Notes
Ghosh, S., Qi, D., An, D., Pulinilkunnil, T., Abrahani, A., Kuo, K.-H., Wambolt, R. B., Allard, M., Innis, S. M., & Rodrigues, B. (2004). Brief Episode of STZ-Induced Hyperglycemia Produces Cardiac Abnormalities in Rats Fed a Diet Rich in N-6 Pufa. American Journal of Physiology. Heart and Circulatory Physiology, 287(6), H2518-2527. doi.org/10.1152/ajpheart.0048...
I discussed this in a blog post. I won’t be doing this for most of the studies we discuss, but I figured it was handy to start with one where I had already done some work!
What's Worse-Carbs or Seed Oils? Understanding a High-PUFA Diet.
tl;dr: The one study I'm aware of that shows conclusively that excess glucose acts as an accelerant for excess omega-6 fat, but it not nearly so harmful without the omega-6, in vivo.
tuckergoodrich.substack.com/p...
If you have any questions about sources for things discussed please ask in the comments.

Пікірлер: 59

  • @mymomsoldlandcruiser7220
    @mymomsoldlandcruiser72205 ай бұрын

    It doesn't matter which one is worse, I stay away from both of these and eat only meat. I feel the best ever in 65 years! I'm going to keep doing what feels good and correct. I will never listen to another vegan or politician or self absorbed Dr. about my nutrition. I will be listening to my gut from now on!

  • @robsprats3900
    @robsprats39005 ай бұрын

    Excellent contextualization and very thoughtful. Only minor complaint is that audio wasn't normalized so everyone came through at a different volume. Found myself have to crank it way up when doc was talking and then crank it back down to avoid getting blasted by the intensity when Tucker came back into the conversation. Wouldn't have been a problem in a quiet room but listened when driving, making it harder to hear a soft voice.

  • @w4rsh1p

    @w4rsh1p

    5 ай бұрын

    Agreed on the audio

  • @TuckerGoodrich0

    @TuckerGoodrich0

    5 ай бұрын

    Thanks for the feedback!

  • @robsprats3900

    @robsprats3900

    5 ай бұрын

    @@TuckerGoodrich0 I should also add that I think this group of people complement each other really well.

  • @hyperTorless
    @hyperTorless5 ай бұрын

    This format is incredibly helpful! Great work thank you!

  • @ogeoge6000
    @ogeoge60005 ай бұрын

    Fantastic, thank you, looking forward to more of these videos.

  • @simonwiltshire7089
    @simonwiltshire70892 ай бұрын

    These posts are super interesting. Thank you. :)

  • @carrikartes1403
    @carrikartes1403Ай бұрын

    So very informative. Thank you so much.

  • @patriciabilotta487
    @patriciabilotta4875 ай бұрын

    Thank you so much for this explanation of seed oils. I had no real understanding of it all.

  • @aprilek6003
    @aprilek60035 ай бұрын

    Very enjoyed this video and style yeah please do more

  • @BrunoCrocco
    @BrunoCrocco5 ай бұрын

    More videos like this one please! 👍💪

  • @ethimself5064
    @ethimself50645 ай бұрын

    Refined oils - 1st of all due to high temperatures these oils have been Polymerized - Plastic

  • @livincincy4498
    @livincincy44985 ай бұрын

    Squirrels eat walnuts in the fall and store fat. Nuts have “ high “ omega 6. In Spain acorns are fed to pigs to make them fat for Iberia hams. The animal models show a seasonal exposure to omega 6 makes mammals store fat. We eat it all year long…

  • @ethimself5064

    @ethimself5064

    5 ай бұрын

    In general they are talking about refined oils I believe. Correct me if I am wrong

  • @paulcallicoat7597

    @paulcallicoat7597

    5 ай бұрын

    You are wrong. Nuts go rancid which if they are shelled or not so the containers always have an expiration date on them. They will last longer if kept in a freezer or refridgerator. Squirrels bury them and if they forget where they buried them the seed germinates as they are exposed to moisture in the soil.Walnut oil has been tested and many that were tested were oxidizing well before the expiration date and the oil was in metal tins sealed under vacuum. You'd think that it wouldn't happen considering it was stored in a vacuum but it did. @@ethimself5064

  • @colinthomson5358

    @colinthomson5358

    4 ай бұрын

    Sure, but eating hundreds of nuts every day will see you in the same place. You might as well drink canola

  • @ethimself5064

    @ethimself5064

    4 ай бұрын

    @@colinthomson5358 🤣🤣🤣

  • @carrikartes1403

    @carrikartes1403

    Ай бұрын

    And seed oils have a much greater amount of omega 6 than nuts do.

  • @w4rsh1p
    @w4rsh1p5 ай бұрын

    Can you make an episode where you show off your zotero library and how you use tags and annotations?

  • @Meathead-10810
    @Meathead-108105 ай бұрын

    I don't like any of these studies because they all include a carbohydrate rich diet, assuming that carbohydrates are always required. If they are using animals that require carbohydrates then they are also using the wrong animals as a comparison. Humans can eat a zero carbohydrate diet and possibly we did for much of our past.

  • @Appleblade
    @Appleblade5 ай бұрын

    I have seen some artful defenses of burying the Minnesota Coronary Experiment... but that BMJ Re-analysis paper from 2016 (available online for free) really makes those defenses look bad.

  • @w4rsh1p
    @w4rsh1p5 ай бұрын

    I wonder if you could convince a dietitian friend of mine who is very skeptical of seed oil deniers.

  • @HaHaroni

    @HaHaroni

    5 ай бұрын

    You'd think a dietitian could hear out Tucker. Maybe it's too much to ask.

  • @w4rsh1p

    @w4rsh1p

    5 ай бұрын

    haha not really. Yesterday she wanted to get dinner at Raising Cane's@@HaHaroni

  • @livincincy4498

    @livincincy4498

    5 ай бұрын

    A dietitian is a clergy member of a dogma. There role is not to interpret the Bible.

  • @tomunderwood4283

    @tomunderwood4283

    5 ай бұрын

    Have them do an experiment on themselves of how long it takes to get a sunburn. High pufa = quicker sunburn

  • @fbrown2014
    @fbrown20145 ай бұрын

    RE: presence in average diet of a given population of adults Both seed oils (ALA) and (fructose + glucose) are worse than their absence.

  • @tomunderwood4283
    @tomunderwood42835 ай бұрын

    I’d like to see a video debunking people who promote seed oils as healthy and anti-inflammatory such as Nutrition Made Simple KZread influencer.

  • @Veganbutchershop
    @Veganbutchershop5 ай бұрын

    Its the combination

  • @tomunderwood4283
    @tomunderwood42835 ай бұрын

    So both Oreos and seed oils lower cholesterol.

  • @pjjmsn
    @pjjmsn5 ай бұрын

    Since glutathione cleans up damage of PUFAs then is taking NAC a good idea since it increases glutathione?

  • @TuckerGoodrich0

    @TuckerGoodrich0

    5 ай бұрын

    Question is: is it necessary, or is cutting seed oils sufficient?

  • @pjjmsn

    @pjjmsn

    5 ай бұрын

    @@TuckerGoodrich0 Good point Tucker. I have been cutting seed oils for about 4 years but have recently become concerned that I have been eating a decent amount of pork and olive oil (genuine, I live in Spain) both of which I have heard contain a lot of linoleic acid. So given the half life of fat in the body I was wondering if NAC could help. Do you think I should worry about pork and olive oil?

  • @TuckerGoodrich0

    @TuckerGoodrich0

    5 ай бұрын

    @@pjjmsn It really depends on the level of LA in those two foods and that of the rest of your diet. I understand both Spanish oil from the Picual olive and some Spanish pork have lower levels of LA than that from other sources. I'd look into that further...

  • @pjjmsn

    @pjjmsn

    5 ай бұрын

    @@TuckerGoodrich0 Thanks Tucker. Much gratitude for brilliant detective work you have done to figure this stuff out. Before I eliminated seed oils, I had severe hip pain along with hip weakness, Now I can say that my legs feel amazing. I also follow to a certain degree your barefoot recomendations along with trying to use footware that aligns with your concepts as well which I also feel has helped a lot. Amazing work!!!

  • @TuckerGoodrich0

    @TuckerGoodrich0

    5 ай бұрын

    @@pjjmsn Glad to hear you're getting a benefit from all of this!

  • @gerlachsieders4578
    @gerlachsieders4578Ай бұрын

    Thank you for rehabilitating carbs, this low-to no-carb nonsense in the ancestral community frustrates me to no end, healthy persons can thrive just fine - or even better - on say 150 gr carbs per day. However, I do value starches over sucrose as a reflection of evolution. Thank you for your voices of reason, as are the voices of Paul Jaminet and his wife.

  • @TuckerGoodrich0

    @TuckerGoodrich0

    Ай бұрын

    I don't know that I've rehabilitated them. I still think a high-carb diet is harmful to humans, and wouldn't recommend it if better options are available.

  • @baguaboy11
    @baguaboy115 ай бұрын

    So is Olive Oil ok .. technically it’s not a seed oil ( and if extra Virgin , it’s not refined at all ) yet it is still relatively high in Omega 6 ?

  • @tsg2009

    @tsg2009

    5 ай бұрын

    Olive oil, avocado oil and coconut oils aren't to bad because to get the oil they are squeezed not heated to extract but they still have toxins and carcogines in them but nowhere near as bad as seed oils

  • @rontiemens2553
    @rontiemens25535 ай бұрын

    Q: what’s worse, carbs or seed oils? A: Yes

  • @niranjanpaul2176

    @niranjanpaul2176

    5 ай бұрын

    Seed oils

  • @w4rsh1p
    @w4rsh1p5 ай бұрын

    Kerley needs a better mic.

  • @TuckerGoodrich0

    @TuckerGoodrich0

    5 ай бұрын

    We got him one, we may need to tune it a bit. We both have the same mic in fact. Thanks for the feedback!

  • @malvanlondon8683
    @malvanlondon86835 ай бұрын

    But aren't there also papers (based on human rather than rodent trials) that say seed oils are good and actually lower mortality?

  • @moomin7461

    @moomin7461

    4 ай бұрын

    Yes.

  • @douglasahart1874
    @douglasahart18745 ай бұрын

    I want to tear my hair out whenever I hear a podcast like this from health professionals! You guys seem never to distinguish between ADULTERATED omega 6s from UNADULTERATED ones! Its like feeding distilled water vs. contaminated water with toxins! Those rat were fed highly processed high Linoleic oils that have been hydrolyzed and made toxic for shelf life. If those rats had been fed cold-pressed, carefully stored linoleic corn or soy oils---the lab results would have been completely different. The Omega-6s are labeled essential fatty acids for a reason. They are needed to sustain life and we don't make them. If you have a diet full of toxic factory Omega-6s, it will replace the good omega-6s in cell membranes and in Cardiolipin and basically cause hypoxia and disrupt the electron transfer chain. If you supplement with cold pressed good linoleic fatty acids, it will improve you cell health. This is the basis for the Budwig Protocol which has cured cases of cancer in the past. As far as cardiolipin, It is naturally made up of LA 80-90% of the fatty acid chains are linoleic fatty acid (LA omega-6) in healthy individuals. If you replace the good linoleic with the toxic, naturally, you will get a "fried" mitochondria!

  • @TuckerGoodrich0

    @TuckerGoodrich0

    4 ай бұрын

    They're not essential, they oxidize in your body.

  • @douglasahart1874

    @douglasahart1874

    4 ай бұрын

    @@TuckerGoodrich0 Give me a break! A omega-6 free diet will cause death. If the body needs them and we can not make them, they are essential. They are protected from oxidation by natural anti-oxidants in the body.

  • @douglasahart1874

    @douglasahart1874

    4 ай бұрын

    They are essential. This was first discovered in 1962 when a woman had abdominal surgery and was fed a diet that was fat-less. She died from that diet. later in 1970 an infant that underwent intestinal surgery was fed IV a diet that was PUFA-less and its health deteriorated. Blood tests showed it could make the other fats, but not Omega-6 or 3. The body can protect the PUFAs with antioxidants. You completely ignored my main point of the difference between cis-omega-6 vs trans-omega-6! Why do you consider them both the same when both are totally different--particularly health wise?

  • @TuckerGoodrich0

    @TuckerGoodrich0

    4 ай бұрын

    @@douglasahart1874 Long-chain omega like DHA or AA are essential, 18 carbon omega like those found in seed oils are not. See research from Mark Puder's lab, or see episode 5 with Tom Brenna. You did not mention cis- vs. trans-omega 6. There are naturally occurring forms of both.

  • @douglasahart1874

    @douglasahart1874

    4 ай бұрын

    Ok, I will check out Puder and Brenna. While some natural trans fats occur in meat and dairy products, the majority of trans fats come from processed foods (i.e., hydrogenated oils) and these are all quite harmful to health. From what I have read from Puder so far, he writes " These findings challenge the essentiality of LA and ALA in the presence of ARA and DHA." The KEY WORDS here is "in the presence"! What his study found may be true, but we as humans do not normally have access to refined ARA or DHA, alone, but we must use the precursors found in nature to manufacture out own ARA or DHA. So in this sense, LA and ALA is very essential! Unlike ARA and DHA, which can be synthesized from precursor fatty acids like LA and ALA, our bodies cannot produce LA and ALA on their own.

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