Aneuploidy or Embryonic Chromosomal Abnormality, is a frequent event in human embryos, and its incidence is higher in oocytes and embryos from women of advanced maternal age. Aneuploidy is also a contributing factor in infertile populations, such as couples with recurrent miscarriages, repetitive implantation failure. However, even in today’s age, many women are still being told that they miscarried due to embryonic chromosomal abnormalities (not the cause of the miscarriage), which means that the baby’s chromosome had some abnormality which led to the miscarriage. After an embryonic demise, some would choose to send the embryo sample for genetic or chromosomal abnormalities analysis to determine the root cause and have a proper closure.
“If the test results reveal that the embryo had chromosomal abnormalities, then we know it was just bad luck.”
We are sure that many women that miscarried have heard this very sentence before. However, how true is that statement exactly?
Common Misconception On Embryonic Chromosomal Abnormality
It is a common misconception that there is nothing the woman can do to prevent embryonic chromosomal abnormalities in subsequent pregnancies, and it depends on your luck.
While it is true that such chromosomal abnormalities are a result of the genetic mutation of the embryo, it is not true that the mutation happened without reason.
There is another school of thought that if you or your partner carry a chromosomal abnormality, it can be passed on to the developing embryo and cause a miscarriage. However, this is also another common misconception.
Causes of Embryonic Chromosomal Abnormality
Every year, Antai hospital has encountered many miscarriages caused by embryonic chromosomal abnormalities. However, further analysis found that most of these patients had unidentified underlying conditions that resulted in embryonic chromosomal abnormalities.
The conditions can be categorized into internal and external environmental factors, and different environments will affect the cell division process.
Internal Environmental Factors
Chromosome abnormalities mostly originate in female meiosis. Recombination between homologous chromosomes is a critical event that occurs in the foetal ovary. The importance of altered recombination pertains to paternally as well as maternally derived trisomies, but as most aneuploidy arises during oogenesis, the female is at greater risk.
Internal environmental factors refer to conditions within the maternal body. Amongst all the patients that miscarried due to embryonic chromosomal abnormalities, 80 percent of them had some form of uterine malformation. The next most significant internal contributor is a reproductive immunological disorder. In particular, there were anti-embryonic antibodies in the maternal body.
Full article: antaihospitals.com/embryonic-...
About Antai Hospital:
Unexplained miscarriages are but unidentified causes of miscarriage. Antai hospital specializes in the diagnosis and treatment of recurrent miscarriages. With a team of medical professionals and exclusive technologies, Antai hospital treats 400-500 cases of miscarriage yearly.
Website: www.antaihospitals.com
Email: enquiry@antaihospitals.com
Patents Exclusive to Antai Hospital:
(1) A method for diagnosing immunity recurrent spontaneous abortion and method for treating and monitoring
patents.google.com/patent/EP1...
(2) A pharmaceutical composition used for treating recurrent spontaneous abortion and method thereof
patents.google.com/patent/EP1...
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