Drugs for Heart Failure

Official Ninja Nerd Website: ninjanerd.org
You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
www.ninjanerd.org/lecture/dru...
Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Drugs for Heart Failure. During this lecture we will begin by discussing the pathophysiology of heart failure. After we have provided a solid foundation to build upon, we will move into the various categories of drugs used to treat heart failure. These will include Beta Blockers, RAAS Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors (ARNI's), Direct Vasodilators, Diuretics, Ivabradine, and Positive Inotropic Agents. We will then review the NYHA Chronic Heart Failure Management Classification and how we manage Acute Heart Failure. As always, at the conclusion of this lecture we will have 10 practice problems to help you truly master this important topic. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Drugs for Heart Failure Introduction
0:45 Pathophysiology of Heart Failure
32:41 Beta Blockers
43:10 RAAS Inhibitors
57:00 Angiotensin Receptor-Neprilysin Inhibitors (ARNI's)
1:07:51 Direct Vasodilators
1:17:26 Diuretics
1:27:41 Ivabradine
1:41:19 Positive Inotropic Agents
2:08:53 NYHA Chronic Heart Failure Management
2:17:57 Acute Heart Failure Management
2:41:54 Drugs for Heart Failure Practice Problems
2:51:50 Comment, Like, SUBSCRIBE!
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Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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#ninjanerd #heartfailure #chf

Пікірлер: 248

  • @inalaura9292
    @inalaura9292 Жыл бұрын

    Not only students, but also pensioners when we are lonely and have nobody to talk to we listen your lectures to know our illnesses to live longer. 60 yo. Thank you that you are. 💐

  • @Amanda-cc8iy

    @Amanda-cc8iy

    11 ай бұрын

    😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊

  • @patriciaburman

    @patriciaburman

    2 ай бұрын

  • @hellenwallo

    @hellenwallo

    18 күн бұрын

    ❤😊

  • @annalussier1431
    @annalussier1431 Жыл бұрын

    Teaching cardiology better than any cardiologist we've seen in med school... thank you for making this available to train doctors and healthcare workers around the world! This channel is a gift to humanity!

  • @areufkingkiddingme

    @areufkingkiddingme

    Жыл бұрын

    Real life and models are very different

  • @tewodrosxwubet

    @tewodrosxwubet

    9 ай бұрын

    for sure

  • @reginaestrada2772

    @reginaestrada2772

    8 ай бұрын

    couldn’t agree more 💯

  • @manofreedom
    @manofreedom8 ай бұрын

    I'm a very busy family medicine doctor with 28 years of ER and urgent care as well as hospitalist service experience and I have to say these Ninja Nerd videos are the BEST teaching videos I have seen. Lot's of deep dive detail that I wish I would have had in medical school, but the internet was just getting up and started in the early 90's when I was in training and residency. This would have been fantastic to have "back in the day." GREAT stuff here.

  • @lucamirea135
    @lucamirea135 Жыл бұрын

    In the name of all the romanian medical students i would like to thank you. We have our residency exam in two weeks and this topic is a very big one in our bibliography and a very troublesome one, may I add. This will come in real handy. Thank you!

  • @yellowindian5134

    @yellowindian5134

    Жыл бұрын

    Indians too

  • @reggiepalmer6157

    @reggiepalmer6157

    Жыл бұрын

    Scottish too❣

  • @user-yn6fi5do5z

    @user-yn6fi5do5z

    Жыл бұрын

    Iraqi too

  • @nikolamarkovic4845

    @nikolamarkovic4845

    Жыл бұрын

    serbian too

  • @giorgosvlachopoulos1615

    @giorgosvlachopoulos1615

    Жыл бұрын

    Greek too

  • @rubenruiz6250
    @rubenruiz6250 Жыл бұрын

    I had heart failure with a LVEF below 40%. With Entresto and after a year on it and then discontinuing it, my LVEF was 65%. I've been without the drug for more than a year now and my heart is still perfect. In other words, I've been cured of heart failure thanks to Entresto!

  • @Albert23456
    @Albert23456Ай бұрын

    I'm dealing with stage 3 heart failure and taking several meds...I learned enough to talk to my doctor thank you❤

  • @sallieukamara5156
    @sallieukamara515626 күн бұрын

    On behalf of the entire medical students in Sierra Leone, we want to thank you for all you have done for us…Thank you Prof Ninja Nerd ❤

  • @yachiapatel
    @yachiapatel Жыл бұрын

    This dude have taught me not only medicine but also, what commitment actually means. Huge and massive respect buddy for your time and commendable efforts.🙌 Can't imagine how you gather all the information from various literatures and put them altogether within just a week that too in a 3-hour video ✌ Tons of love and appreciation to you and your team 🙌❤ please keep doing 🌠

  • @tube7663
    @tube7663 Жыл бұрын

    I AM HABTAMU TEKALIGN FROM ETHIOPIA I AM CLINICAL PHARMACY STUDENT SINCE FIRST YEAR I AM USING YOUR TUTORIAL VIDEO ITS SO SUPPORTIVE NOW I AM ONE OF TOP SCORER THANK YOU BIG BRO NINJA

  • @mr.ssj3847
    @mr.ssj3847 Жыл бұрын

    bro, mad respect and props. seriously your videos are great, well researched and I can tell you have spent a lot of time gathering all this info together. from the bottom of my heart. thank you fam!

  • @elyastesfamichael6527

    @elyastesfamichael6527

    Жыл бұрын

    You are really Ninja bro, you make the difficult easy😉.

  • @ednatrepanier
    @ednatrepanier2 ай бұрын

    You are the best lecturer ever! You are very smart nerd ninja! I adore your ability to share your enormous knowledge!!!

  • @faisalmehedi2490
    @faisalmehedi2490 Жыл бұрын

    Medical lectures owe you a lot..You are a boss man..

  • @esammohammad5978
    @esammohammad5978 Жыл бұрын

    Thanks for you bro from my heart, your the the best lecturer in the world. Keep going Greating from sudan 🇸🇩🇸🇩

  • @MH-yr6bp
    @MH-yr6bp9 ай бұрын

    I am not even a physian but in another medical field and enjoy the courses.

  • @ednatrepanier
    @ednatrepanier2 ай бұрын

    You are the best person ever who can discuss anything you’re asked to do. You have a unique way of explaining everything so we can understand. Pls keep doing your education videos. Plenty of medical staffs are benefiting out of them like me. I love you!!!

  • @aminaqamar50
    @aminaqamar503 ай бұрын

    I can't listen to any other person having 3 hours of lectures but it's only youuuuuu to whom I can listen 😭

  • @Melaniexb1
    @Melaniexb1 Жыл бұрын

    From someone who found Dr Ninja looking for just this subject, your other video on this topic helped me know that my husband was on the correct drugs for his possible class 2 of heart failure. (He had a quintuple bi -pass just just 3 1/2 years before.) Which then lead to the three scheduled tests US of abdomen, CT, and an Echo! All waiting to take place, to help find the cause of his now (some 70 lbs )of Water weight gain in 4 weeks time!

  • @mariamadenola6534
    @mariamadenola6534 Жыл бұрын

    I am starting a cardiology posting and all I can say is thank you very much for what you do.

  • @sibuleleshude3366
    @sibuleleshude3366 Жыл бұрын

    One of the best teachers in the world 🌎 ❤ I'm learning a lot from your lectures. Keep it up guys, your work is highly appreciated All the way from South 🇿🇦 ❤

  • @karenmoore2972
    @karenmoore297229 күн бұрын

    This guy does such an AMAZING job of explaining these concepts!! I hope he continues to teach bc many are not able to explain complex mechanisms this well, making it easy to hold our attention in my opinion!! His pace of speaking is just perfect!, easy to keep up with & definitely not dull & boring!! Thank you!!

  • @user-jg1cu2qv5p
    @user-jg1cu2qv5p Жыл бұрын

    This as a phenomenal lecture. I listened to some of your stuff during nursing school and am now studying for PCCN and wow, so helpful. Thank you!

  • @aacc8466
    @aacc8466 Жыл бұрын

    you, your team, your spouse, your dog, your mailman and your mama....IS THE MAN. Thank You for helping out the little guy !!!!!

  • @amandavitaglian5859
    @amandavitaglian5859 Жыл бұрын

    so impressed by the depth of your knowledge and how well you are able to explain it. You're a tru master of your craft.

  • @salvadorhirth2919
    @salvadorhirth2919 Жыл бұрын

    Your videos are so good that I always hit the like before watching. Congratulations on your dedication and knowledge!

  • @robynneRN
    @robynneRN Жыл бұрын

    I never knew medicine could be this interesting!! BRAVO!

  • @em8066
    @em8066 Жыл бұрын

    I wish this was published prior to my ICU rotation in PA school, but it's still a great review now. Thanks!

  • @demetrikasher1237
    @demetrikasher1237 Жыл бұрын

    Awesome video, I have heart failure and like to review what my meds are doing for me every now and then haha. Losartan, Carvedilol, Warfarin, spironolactone, and a few others in the past. Thanks everyone in the medical field!

  • @garrettross9999
    @garrettross99993 ай бұрын

    EMT-b and nursing student here. Thank you. I believe I have a better and more in depth understanding of the material than any of my peers now.

  • @griselgaspar6904
    @griselgaspar6904 Жыл бұрын

    Amazing video Zack! You have an amazing talent to teach! You make all these concepts so easy to understand!

  • @annjelasantiago8057
    @annjelasantiago8057 Жыл бұрын

    Thank you for this awesome lecture. Your knowledge and commitment is remarkable.

  • @labs2798
    @labs27987 ай бұрын

    Great content as always. Easy to understand, easy to revise and learn from. Your videos are a lifeline!

  • @shoukatmirza5014
    @shoukatmirza50147 ай бұрын

    Great work. Doctors can easily make their right approach towards patients and diseases. You make it too easy. God bless you for your great work.

  • @jenispatel1024
    @jenispatel1024 Жыл бұрын

    Due respect 🙏 .....!!bow down to u dr Zack🙌🙌🙌🙌

  • @nanadarkoampem
    @nanadarkoampem5 ай бұрын

    This is one of the best educative sites ever visited

  • @JodyLeeSchroeder
    @JodyLeeSchroeder Жыл бұрын

    literally was asked to do this by my professor today - let''s go ! Cant wait for this video :) Love you ninja nerds

  • @alexistremblay3604
    @alexistremblay3604 Жыл бұрын

    hey, I'm not a medical student or anything but I love genuinely learning about how the body functions, thank you so much for making this knowledge available for free, actually would cost thousands of dollars of books to learn this stuff otherwise. actual chad

  • @yvonnevillalba7722
    @yvonnevillalba77228 ай бұрын

    Thank you for this detailed explanation. You are a fantastic teacher.

  • @hdskl2150
    @hdskl215011 ай бұрын

    This is so awesome. I have a child with chd and its sooooooooo helpful to hear what these meds are doing

  • @trudikaye2326
    @trudikaye2326Ай бұрын

    LOVE his energy for teaching!!!

  • @ngoziemozie9779
    @ngoziemozie9779 Жыл бұрын

    You just dymystified heart failure with low EF. Thank you so very much for this presentation

  • @SortedBody
    @SortedBody4 ай бұрын

    Thank you very much for your time and effort producing this learning material. It will help me in my practice and benefit hundreds of my patients.

  • @fatimaalarabi5581
    @fatimaalarabi5581 Жыл бұрын

    My exam is on the 5th of January And I'm so thankful cos I'm studying pharma from your wonderful channel It's so entertaining to learn it from you zach Thank you so much for your magnificent effort 💗

  • @mathiasmontalvo3683
    @mathiasmontalvo36838 ай бұрын

    Thank you for this detailed explanation. It is truly a fantastic video.

  • @user-qp2br8lh1h
    @user-qp2br8lh1h2 ай бұрын

    You are so intelligent, You have such a cool way of explaining things and I absolutely love your board and marker pens. Keep up the good work.

  • @JETMDS
    @JETMDS7 ай бұрын

    Thank you so much for educating patients with their diseases CHF.

  • @hoangthinh8007
    @hoangthinh80072 ай бұрын

    thank you so much for your lecture and your passionate teaching. it really really helps

  • @salahal-saleh3076
    @salahal-saleh3076 Жыл бұрын

    Just in time! Thank you

  • @noormamoon8920
    @noormamoon89203 ай бұрын

    From all different countries, we support you, love you, and wish all best for you

  • @brucenome989
    @brucenome989 Жыл бұрын

    I enjoy all your videos I think I'm ready for medical school now after watching your videos and the way you teach the lecture

  • @katiela972
    @katiela97224 күн бұрын

    wow this is helping me drastically. I am an ICU new grad and this is very helpful! THANK YOU!!!

  • @irame5701
    @irame5701Ай бұрын

    Zach is a such amazing human being- lovely and talented. ❤️

  • @hansbeukers7725
    @hansbeukers77254 ай бұрын

    I am a 74 year old male with a pacemaker and use anti hypertension drugs. I did not want to use metaprolol because I am still a racing cyclist and I want a high cardiac output for that reason. You told that metaprolol initially lowers the heartrate (and therfore the Cardiac output) but after some time it even increases the cardiac output. That is nice to hear and I wished I knew that earlier. Thank you! Today I use Perindopril, Nifedipine, Xarelto and Jardiance and I feel fine.

  • @ndukeabasiinyang9421
    @ndukeabasiinyang9421Ай бұрын

    Thank you Dr., for this awesome video

  • @user-yq3fz7gc1z
    @user-yq3fz7gc1z3 ай бұрын

    No matter how much i try .. i can't thank u enough

  • @oliviafransson8882
    @oliviafransson8882 Жыл бұрын

    This is amazing! Thank you so much!

  • @asanglajamir
    @asanglajamir Жыл бұрын

    Love love love your videos. Please keep posting on more and more new topics

  • @tamngoc6046
    @tamngoc60462 ай бұрын

    Thank you Ninja Nerd very much!

  • @SuperLittleTyke
    @SuperLittleTyke3 ай бұрын

    I'm male, 78 (almost) and I was diagnosed with heart failure 4 months ago with an ejection fraction of 25% to 35%. I'm now taking a cocktail of drugs: Entresto, Apixaban, Rosuvastatin, Furosemide, Bisoprolol, Eplerenone, Dapagliflozin and Aspirin. 11 years ago I had a triple CABG and made a full recovery. Three months after the operation I had a follow-up with a cardiologist and had an echocardiogram. The result of that, however, was an EF of 60%, no noticeable valve disease and the heart was pronounced good. In the intervening years I lost a lot of weight by counting calories and I modified my diet considerably with grains, wholemeal bread, lots of fish, including oily fish. What I want to know is how the EF can sink from 60% to as low as 25% in 11 years.

  • @EntEmpireTV
    @EntEmpireTV3 ай бұрын

    Thanks man , you are a great help to medical students

  • @robertoluis9238
    @robertoluis923810 күн бұрын

    a lot of info presented very well.

  • @marigorgadze732
    @marigorgadze732 Жыл бұрын

    You are doing really great job ❤️ thanks for your effort ❤️

  • @paulbaddoc2470
    @paulbaddoc2470 Жыл бұрын

    Zach Murphy the great 🖤🇸🇸

  • @ammaraltayib9891
    @ammaraltayib98919 ай бұрын

    So insightful thank you so much and much appreciated

  • @mercyochoa2135
    @mercyochoa21359 ай бұрын

    Your video to this topic is impressive, Brilliant, thank you

  • @awalehussein9614
    @awalehussein9614 Жыл бұрын

    Thanks you Dr ninjanerd you are best lectural for medical department, we hope next video for pharmacology will be Diabetes mellitus drugs and their classification in best teaching and memory way

  • @deepakrtr4840
    @deepakrtr4840 Жыл бұрын

    Bro...I have no words for these masterpiece.. Greetings fm 🇮🇳

  • @kusineraunoniebyang6102
    @kusineraunoniebyang61023 ай бұрын

    Thank you so much for sharing in more in-depth information on these drugs. I am HFrEF

  • @duaajawed2273
    @duaajawed22738 ай бұрын

    Thank you so much for saving my semester! ❤

  • @irereomio1797
    @irereomio1797 Жыл бұрын

    Thank you for your lectures

  • @entsarzaid
    @entsarzaid8 ай бұрын

    Im so grateful for you prof

  • @meimei9057
    @meimei9057 Жыл бұрын

    Thank you dear!

  • @stephen8289
    @stephen8289Ай бұрын

    Excellent tutorial!

  • @Fofa_b_q
    @Fofa_b_q19 күн бұрын

    Thank you so much ❤

  • @arduh
    @arduh Жыл бұрын

    can you please continue on the cell biology videos, for example, the techniques for monitoring and manipulating cells and genetic material? you are the best teacher ever:)

  • @CarolReidCA
    @CarolReidCAАй бұрын

    I'm watching again. The signals from the heart to the medulla obligata is by the IXth (9th) cranial nerve, or the glossopharangeal nerve. The Xth (10th) is the vagus never. I had to look it up to be sure, as it had been a while, but hopefully, that's helpful for someone. The carotid sinus baroreceptors are innervated by the carotid sinus nerve branch of the glossopharyngeal nerve. Their stimulation results in heart rate reduction mediated by the vagus nerve. Thanks for your lectures!

  • @CadeChurch
    @CadeChurch Жыл бұрын

    Thank you!

  • @tewodrosxwubet
    @tewodrosxwubet9 ай бұрын

    thank you bro like really we are all grateful you exist ,

  • @amanalok4647
    @amanalok464729 күн бұрын

    I’m a med tech entrepreneur and you are the reason my company exists ❤

  • @unicefox_sharksit109
    @unicefox_sharksit109 Жыл бұрын

    NOT ONLY YOU ARE AN AMAZING TEACHER, YOU ARE SO FUNNY TOO

  • @ilytito2112
    @ilytito2112 Жыл бұрын

    thanks a bunch

  • @kabirmoz5369
    @kabirmoz536914 күн бұрын

    Thanks!

  • @joudizawet7573
    @joudizawet7573 Жыл бұрын

    Can't imagine studying medicine without your videos! :')❤❤❤

  • @taghridmohamed7838
    @taghridmohamed78382 ай бұрын

    Thank you

  • @edanurdinc8344
    @edanurdinc8344 Жыл бұрын

    thank you for everything

  • @sudharshikawshalya3733
    @sudharshikawshalya3733 Жыл бұрын

    I am thankful you to for your interesting teaching methods.great work. I m interested very.

  • @mylittlcornr
    @mylittlcornr Жыл бұрын

    THANKYOU so much!

  • @sayidali8142
    @sayidali8142 Жыл бұрын

    Thank you Dr ninja

  • @5pmShaun
    @5pmShaun5 ай бұрын

    You are the bomb! Better lectures than during med school The why’s of pharm!

  • @janemercado5815
    @janemercado5815 Жыл бұрын

    Just amazing! he is like the Bob Ross of medical teaching!

  • @I_am_Anne

    @I_am_Anne

    4 ай бұрын

    Yes. Exactly. 🤣😂🤣😂 It is funny because it is true.

  • @moradzayed
    @moradzayed6 ай бұрын

    thank you so much great effort

  • @Scoob-hb5eb
    @Scoob-hb5eb2 ай бұрын

    Just want to say you have gotten me through nursing school. Used you last semester and got an A when the previous semester I got a C.

  • @nw3251
    @nw3251 Жыл бұрын

    Thanks Dr ...from Yemen

  • @Xiphapha
    @Xiphapha9 ай бұрын

    Respect,luv and bundle of thnx

  • @lich5655
    @lich5655 Жыл бұрын

    In Australia we've added SGLT2 inhibitors like dapagliflozin to our first line therapy along with the beta blockers and ARNI + valsartan. It's unknown why but seems to be cardioprotective and improve outcomes, likely due to the diuretic effect.

  • @em8066

    @em8066

    Жыл бұрын

    We also learned about the role of SGLT2-i in my PA program in the US. Seems especially useful given the frequent comorbidity of HF and DM.

  • @prithvirajdhonde2430

    @prithvirajdhonde2430

    Жыл бұрын

    In NHS too we add DAPA 10 along with others

  • @shahidgillani292
    @shahidgillani2922 ай бұрын

    Thanks

  • @user-dh8dx4qi9h
    @user-dh8dx4qi9h Жыл бұрын

    When are you coming at India sir???

  • @JuliaJones-vi9zx
    @JuliaJones-vi9zx9 ай бұрын

    Very beneficial. Thank you!

  • @thewaddy
    @thewaddy Жыл бұрын

    Thank you.

  • @mathewskataso8907
    @mathewskataso8907 Жыл бұрын

    amazing stuff as usual

  • @tl4340
    @tl4340 Жыл бұрын

    1:04:15 Actually, the 2022 AHA/ACC Guideline on heart failure now suggests that ARNi are now first-line RASi in HFrEF, *ahead* of ACEIs and ARBs. ARNi first, then ACEI if ARNi can't be tolerated (or afforded), then ARB if ACEI can't be tolerated (e.g., angioedema, bradykinin cough). This recommendation is different than what you say in here regarding order of priority. Nitpicking aside, this is a *fabulous* teaching video.

  • @Vamparina413

    @Vamparina413

    3 ай бұрын

    Ah yes coz that was what I was given which is the Entresto when I was diagnosed with CHF last year with reduced EF.