Drugs for Heart Failure
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Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Drugs for Heart Failure. During this lecture we will begin by discussing the pathophysiology of heart failure. After we have provided a solid foundation to build upon, we will move into the various categories of drugs used to treat heart failure. These will include Beta Blockers, RAAS Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors (ARNI's), Direct Vasodilators, Diuretics, Ivabradine, and Positive Inotropic Agents. We will then review the NYHA Chronic Heart Failure Management Classification and how we manage Acute Heart Failure. As always, at the conclusion of this lecture we will have 10 practice problems to help you truly master this important topic. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Drugs for Heart Failure Introduction
0:45 Pathophysiology of Heart Failure
32:41 Beta Blockers
43:10 RAAS Inhibitors
57:00 Angiotensin Receptor-Neprilysin Inhibitors (ARNI's)
1:07:51 Direct Vasodilators
1:17:26 Diuretics
1:27:41 Ivabradine
1:41:19 Positive Inotropic Agents
2:08:53 NYHA Chronic Heart Failure Management
2:17:57 Acute Heart Failure Management
2:41:54 Drugs for Heart Failure Practice Problems
2:51:50 Comment, Like, SUBSCRIBE!
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Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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#ninjanerd #heartfailure #chf
Пікірлер: 248
Not only students, but also pensioners when we are lonely and have nobody to talk to we listen your lectures to know our illnesses to live longer. 60 yo. Thank you that you are. 💐
@Amanda-cc8iy
11 ай бұрын
😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊
@patriciaburman
2 ай бұрын
❤
@hellenwallo
18 күн бұрын
❤😊
Teaching cardiology better than any cardiologist we've seen in med school... thank you for making this available to train doctors and healthcare workers around the world! This channel is a gift to humanity!
@areufkingkiddingme
Жыл бұрын
Real life and models are very different
@tewodrosxwubet
9 ай бұрын
for sure
@reginaestrada2772
8 ай бұрын
couldn’t agree more 💯
I'm a very busy family medicine doctor with 28 years of ER and urgent care as well as hospitalist service experience and I have to say these Ninja Nerd videos are the BEST teaching videos I have seen. Lot's of deep dive detail that I wish I would have had in medical school, but the internet was just getting up and started in the early 90's when I was in training and residency. This would have been fantastic to have "back in the day." GREAT stuff here.
In the name of all the romanian medical students i would like to thank you. We have our residency exam in two weeks and this topic is a very big one in our bibliography and a very troublesome one, may I add. This will come in real handy. Thank you!
@yellowindian5134
Жыл бұрын
Indians too
@reggiepalmer6157
Жыл бұрын
Scottish too❣
@user-yn6fi5do5z
Жыл бұрын
Iraqi too
@nikolamarkovic4845
Жыл бұрын
serbian too
@giorgosvlachopoulos1615
Жыл бұрын
Greek too
I had heart failure with a LVEF below 40%. With Entresto and after a year on it and then discontinuing it, my LVEF was 65%. I've been without the drug for more than a year now and my heart is still perfect. In other words, I've been cured of heart failure thanks to Entresto!
I'm dealing with stage 3 heart failure and taking several meds...I learned enough to talk to my doctor thank you❤
On behalf of the entire medical students in Sierra Leone, we want to thank you for all you have done for us…Thank you Prof Ninja Nerd ❤
This dude have taught me not only medicine but also, what commitment actually means. Huge and massive respect buddy for your time and commendable efforts.🙌 Can't imagine how you gather all the information from various literatures and put them altogether within just a week that too in a 3-hour video ✌ Tons of love and appreciation to you and your team 🙌❤ please keep doing 🌠
I AM HABTAMU TEKALIGN FROM ETHIOPIA I AM CLINICAL PHARMACY STUDENT SINCE FIRST YEAR I AM USING YOUR TUTORIAL VIDEO ITS SO SUPPORTIVE NOW I AM ONE OF TOP SCORER THANK YOU BIG BRO NINJA
bro, mad respect and props. seriously your videos are great, well researched and I can tell you have spent a lot of time gathering all this info together. from the bottom of my heart. thank you fam!
@elyastesfamichael6527
Жыл бұрын
You are really Ninja bro, you make the difficult easy😉.
You are the best lecturer ever! You are very smart nerd ninja! I adore your ability to share your enormous knowledge!!!
Medical lectures owe you a lot..You are a boss man..
Thanks for you bro from my heart, your the the best lecturer in the world. Keep going Greating from sudan 🇸🇩🇸🇩
I am not even a physian but in another medical field and enjoy the courses.
You are the best person ever who can discuss anything you’re asked to do. You have a unique way of explaining everything so we can understand. Pls keep doing your education videos. Plenty of medical staffs are benefiting out of them like me. I love you!!!
I can't listen to any other person having 3 hours of lectures but it's only youuuuuu to whom I can listen 😭
From someone who found Dr Ninja looking for just this subject, your other video on this topic helped me know that my husband was on the correct drugs for his possible class 2 of heart failure. (He had a quintuple bi -pass just just 3 1/2 years before.) Which then lead to the three scheduled tests US of abdomen, CT, and an Echo! All waiting to take place, to help find the cause of his now (some 70 lbs )of Water weight gain in 4 weeks time!
I am starting a cardiology posting and all I can say is thank you very much for what you do.
One of the best teachers in the world 🌎 ❤ I'm learning a lot from your lectures. Keep it up guys, your work is highly appreciated All the way from South 🇿🇦 ❤
This guy does such an AMAZING job of explaining these concepts!! I hope he continues to teach bc many are not able to explain complex mechanisms this well, making it easy to hold our attention in my opinion!! His pace of speaking is just perfect!, easy to keep up with & definitely not dull & boring!! Thank you!!
This as a phenomenal lecture. I listened to some of your stuff during nursing school and am now studying for PCCN and wow, so helpful. Thank you!
you, your team, your spouse, your dog, your mailman and your mama....IS THE MAN. Thank You for helping out the little guy !!!!!
so impressed by the depth of your knowledge and how well you are able to explain it. You're a tru master of your craft.
Your videos are so good that I always hit the like before watching. Congratulations on your dedication and knowledge!
I never knew medicine could be this interesting!! BRAVO!
I wish this was published prior to my ICU rotation in PA school, but it's still a great review now. Thanks!
Awesome video, I have heart failure and like to review what my meds are doing for me every now and then haha. Losartan, Carvedilol, Warfarin, spironolactone, and a few others in the past. Thanks everyone in the medical field!
EMT-b and nursing student here. Thank you. I believe I have a better and more in depth understanding of the material than any of my peers now.
Amazing video Zack! You have an amazing talent to teach! You make all these concepts so easy to understand!
Thank you for this awesome lecture. Your knowledge and commitment is remarkable.
Great content as always. Easy to understand, easy to revise and learn from. Your videos are a lifeline!
Great work. Doctors can easily make their right approach towards patients and diseases. You make it too easy. God bless you for your great work.
Due respect 🙏 .....!!bow down to u dr Zack🙌🙌🙌🙌
This is one of the best educative sites ever visited
literally was asked to do this by my professor today - let''s go ! Cant wait for this video :) Love you ninja nerds
hey, I'm not a medical student or anything but I love genuinely learning about how the body functions, thank you so much for making this knowledge available for free, actually would cost thousands of dollars of books to learn this stuff otherwise. actual chad
Thank you for this detailed explanation. You are a fantastic teacher.
This is so awesome. I have a child with chd and its sooooooooo helpful to hear what these meds are doing
LOVE his energy for teaching!!!
You just dymystified heart failure with low EF. Thank you so very much for this presentation
Thank you very much for your time and effort producing this learning material. It will help me in my practice and benefit hundreds of my patients.
My exam is on the 5th of January And I'm so thankful cos I'm studying pharma from your wonderful channel It's so entertaining to learn it from you zach Thank you so much for your magnificent effort 💗
Thank you for this detailed explanation. It is truly a fantastic video.
You are so intelligent, You have such a cool way of explaining things and I absolutely love your board and marker pens. Keep up the good work.
Thank you so much for educating patients with their diseases CHF.
thank you so much for your lecture and your passionate teaching. it really really helps
Just in time! Thank you
From all different countries, we support you, love you, and wish all best for you
I enjoy all your videos I think I'm ready for medical school now after watching your videos and the way you teach the lecture
wow this is helping me drastically. I am an ICU new grad and this is very helpful! THANK YOU!!!
Zach is a such amazing human being- lovely and talented. ❤️
I am a 74 year old male with a pacemaker and use anti hypertension drugs. I did not want to use metaprolol because I am still a racing cyclist and I want a high cardiac output for that reason. You told that metaprolol initially lowers the heartrate (and therfore the Cardiac output) but after some time it even increases the cardiac output. That is nice to hear and I wished I knew that earlier. Thank you! Today I use Perindopril, Nifedipine, Xarelto and Jardiance and I feel fine.
Thank you Dr., for this awesome video
No matter how much i try .. i can't thank u enough
This is amazing! Thank you so much!
Love love love your videos. Please keep posting on more and more new topics
Thank you Ninja Nerd very much!
I'm male, 78 (almost) and I was diagnosed with heart failure 4 months ago with an ejection fraction of 25% to 35%. I'm now taking a cocktail of drugs: Entresto, Apixaban, Rosuvastatin, Furosemide, Bisoprolol, Eplerenone, Dapagliflozin and Aspirin. 11 years ago I had a triple CABG and made a full recovery. Three months after the operation I had a follow-up with a cardiologist and had an echocardiogram. The result of that, however, was an EF of 60%, no noticeable valve disease and the heart was pronounced good. In the intervening years I lost a lot of weight by counting calories and I modified my diet considerably with grains, wholemeal bread, lots of fish, including oily fish. What I want to know is how the EF can sink from 60% to as low as 25% in 11 years.
Thanks man , you are a great help to medical students
a lot of info presented very well.
You are doing really great job ❤️ thanks for your effort ❤️
Zach Murphy the great 🖤🇸🇸
So insightful thank you so much and much appreciated
Your video to this topic is impressive, Brilliant, thank you
Thanks you Dr ninjanerd you are best lectural for medical department, we hope next video for pharmacology will be Diabetes mellitus drugs and their classification in best teaching and memory way
Bro...I have no words for these masterpiece.. Greetings fm 🇮🇳
Thank you so much for sharing in more in-depth information on these drugs. I am HFrEF
Thank you so much for saving my semester! ❤
Thank you for your lectures
Im so grateful for you prof
Thank you dear!
Excellent tutorial!
Thank you so much ❤
can you please continue on the cell biology videos, for example, the techniques for monitoring and manipulating cells and genetic material? you are the best teacher ever:)
I'm watching again. The signals from the heart to the medulla obligata is by the IXth (9th) cranial nerve, or the glossopharangeal nerve. The Xth (10th) is the vagus never. I had to look it up to be sure, as it had been a while, but hopefully, that's helpful for someone. The carotid sinus baroreceptors are innervated by the carotid sinus nerve branch of the glossopharyngeal nerve. Their stimulation results in heart rate reduction mediated by the vagus nerve. Thanks for your lectures!
Thank you!
thank you bro like really we are all grateful you exist ,
I’m a med tech entrepreneur and you are the reason my company exists ❤
NOT ONLY YOU ARE AN AMAZING TEACHER, YOU ARE SO FUNNY TOO
thanks a bunch
Thanks!
Can't imagine studying medicine without your videos! :')❤❤❤
Thank you
thank you for everything
I am thankful you to for your interesting teaching methods.great work. I m interested very.
THANKYOU so much!
Thank you Dr ninja
You are the bomb! Better lectures than during med school The why’s of pharm!
Just amazing! he is like the Bob Ross of medical teaching!
@I_am_Anne
4 ай бұрын
Yes. Exactly. 🤣😂🤣😂 It is funny because it is true.
thank you so much great effort
Just want to say you have gotten me through nursing school. Used you last semester and got an A when the previous semester I got a C.
Thanks Dr ...from Yemen
Respect,luv and bundle of thnx
In Australia we've added SGLT2 inhibitors like dapagliflozin to our first line therapy along with the beta blockers and ARNI + valsartan. It's unknown why but seems to be cardioprotective and improve outcomes, likely due to the diuretic effect.
@em8066
Жыл бұрын
We also learned about the role of SGLT2-i in my PA program in the US. Seems especially useful given the frequent comorbidity of HF and DM.
@prithvirajdhonde2430
Жыл бұрын
In NHS too we add DAPA 10 along with others
Thanks
When are you coming at India sir???
Very beneficial. Thank you!
Thank you.
amazing stuff as usual
1:04:15 Actually, the 2022 AHA/ACC Guideline on heart failure now suggests that ARNi are now first-line RASi in HFrEF, *ahead* of ACEIs and ARBs. ARNi first, then ACEI if ARNi can't be tolerated (or afforded), then ARB if ACEI can't be tolerated (e.g., angioedema, bradykinin cough). This recommendation is different than what you say in here regarding order of priority. Nitpicking aside, this is a *fabulous* teaching video.
@Vamparina413
3 ай бұрын
Ah yes coz that was what I was given which is the Entresto when I was diagnosed with CHF last year with reduced EF.