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In this lecture EKG is going to cover drug distribution. We’re going to break down what drug distribution is, the factors influencing this process, body fluid compartments and the apparent volume of distribution.
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Lecture Overview:
0:00 Intro
1:05 Body Fluid Compartments (Total Body Water, ECF, ICF)
2:45 Solubility & Blood Flow
4:55 Protein Binding
9:15 Capillary Permeability & Specific Barriers
11:50 Apparent Volume of Distribution
✏️ All diagrams were made by EKG.
For educational purposes only; NOT medical or other advice.
Lecture Source:
Ritter, J., Flower, R.J., Henderson, G., Yoon Kong Loke and Rang, H.P. (2018). Rang and Dale’s Pharmacology. 9th ed. Endinburgh: Elsevier.
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