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WEC 50: Cruz vs. Benavidez 2 was a mixed martial arts event held by World Extreme Cagefighting that took place on August 18, 2010 at The Pearl at The Palms in Las Vegas.
This event marked WEC's first visit to Las Vegas since WEC 45 in December 2009 and was also shown on the TV channel Versus.
Dominick Cruz made his first title defense against Joseph Benavidez in the main event. The bout was a rematch of their contest at WEC 42, in which Cruz handed Benavidez his first career loss, via decision. Cruz defeated Benavidez again via split decision and retained his title. Cruz broke his left hand in the fight.