David Sinclair on NUTRITION for Longevity | Study Explained | Different Foods' Impact on mTOR
To increase your longevity and defend yourself against aging,
you need your diet to be spot on.
You need the specifics.
You must feel certain about what to eat and how much -
In the surest way from the 100 years of metabolic research.
And there is nothing surer in longevity than mTOR, a genetic pathway that controls longevity. Because it extends 30% of lifespan in all animal forms.
But how does each food affect this longevity pathway?
How much should you eat?
Today, we’ll see Dr. David Sinclair talking about different diets for longevity.
We’ll try to explain his take by covering specific foods and their impact on mTOR.
So you WILL design your ideal longevity lifestyle.
And only if you love steaks - you’ll discover how to eat a steak and still keep mTOR low for the day
If all that makes you hungry, it will get much worse.
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If you missed the previous videos on protein:
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Credits: Scott Buckley
Disclaimer & Disclosure: The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Rimon, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.
Rimon is not a medical doctor. If there is a contradiction between the advice here to your doctor or local authorities, always go with the doctor and the authorities.
Statements made, or solutions suggested in this video and/or at this channel are not intended to diagnose, treat, cure, or prevent any disease.
The statements are not contradictory to first following authorities' guidelines of social distancing and hygiene.
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Generally, plant protein is lower in methionine and higher in glycine. That's exactly what you're looking for longevity wise. I'm not against meat at all. But the benefits of fish is mostly omega3, b12 and glycine. It's 2022 and fish is getting more contaminated every year. Stick with small young fish like sardines, anchovy and herring. Tuna is already risky imho.
@WellnessMessiah
Жыл бұрын
You're right mark As you said, we've contaminated the oceans and it's best to select smaller fish. But it's our fault for this ocean disaster. You're right, small young fish like sardines, anchovy, and herring are the best. I love mackerel too!
@timpenfield5
Жыл бұрын
Fish is awesome, but with more nuke subs being built every year, more nuke contamination dumped in the ocean every year, then pesticides, fossil fuels, runoff, etc.... very risky, I eat Moroccan crown prince sardines, taste great, like chicken, a little salmon, chicken, thats it for meat, miss shrimp,lobster, etc.... but the hell with it, Ocean is scary. just fukishima alone,
@furstylist
Жыл бұрын
What about eggs?
@BarryAnderson
Жыл бұрын
@@WellnessMessiah I do the same and I just added your channel to my interest and hit the big bell to get more of your new content of researched health and culinary know-how for longevity. I am a young 68 years and follow the ways of the Blue Zones from founder Dan Beauttner
@WellnessMessiah
Жыл бұрын
@@BarryAnderson Great to meet you, Barry! It's a big compliment from you.
Very good info Rimon. I like your presentation style -- concise, clear and useful. Looking forward to your future vlogs.
@WellnessMessiah
Жыл бұрын
You're very kind Rudy. Happy to have found you.
I'm taking notes. Great stuff man!
Eat a balanced diet of good quality meat and a good quality variation of vegetables. I’m glad all of these studies are finally circling back to what most people with commonsense knew, we’re omnivores.
seem like each advocate manages to include and justify the food that they like. really enjoy the video. much respect for dr. Sinclair
Thanks for all your great advice. I really enjoy watching your videos, they provide a lot of knowledge and are very helpful on a daily basis in choosing food when shopping, etc. Thank you ❤✨
Thank you for the quality video Rimon, hope to see more content on antioxidants and polyphenols too.
@WellnessMessiah
Жыл бұрын
You're very kind KZ. In 2 weeks' time, you'll get a mind-blowing video on that exact subject. It's a project I've been working on for the last 2 months, took me covering nearly 200 studies, and will include polyphenols as a group. More info here. kzread.info/dash/bejne/i3V7tKeifrCxYMo.html
@KzLollapalooza
Жыл бұрын
@@WellnessMessiah thank you for your reply Rimon! I'm excited!
Critical thinking, informative, concise, and practical! Thank you so much for the video.
Thanks for the video
Very enlightening. Most people would not think about the amino acid profile of their higher protein foods.
@WellnessMessiah
Жыл бұрын
Hey dove how are you? Yes, it's a bit of pain in the... to do this analysis. But it's worth it because you get it right once and have lifetime habits.Thank you about your compliment, you're very kind.
Great info 🤗🍀
Thank you friend
great video
Your English is fine. Thanks for the informative video.
@WellnessMessiah
Жыл бұрын
You're very kind! Thank you!
I like the presentation. A bit complicated but precise. I'm 81 and exercise a lot. I can't stand fish and never could eat it. So far so good. Thank you
@WellnessMessiah
Жыл бұрын
nice to meet you, Patrick!
@hedgehogthesonic3181
Жыл бұрын
Why can't you eat fish?
Thank you Rimon, it is a good balance with David's vegan diet. I do like eggs, dairy and fish. Activated nuts where available.
Good video.
@WellnessMessiah
Жыл бұрын
Thank you Olya you're very kind
Great vídeo! Thank you! BRAZIL!
@WellnessMessiah
Жыл бұрын
Nice to meet you Ildevanio, was rooting for you in the world cup
Thanks for the info. I’m eating the ideal diet and I didn’t know it, but the best part about it is that I find it delicious! I’ve recently added goji berries to my diet at breakfast time. They energise me and lift my mood! Also a lift turmeric each day is good for you!
@Jiwonsharma
Жыл бұрын
Whats your intake of carbs
@monnoo8221
Жыл бұрын
goji : high in sugar, high in antiox, high in melatonin ... just not too much of it ...which is difficult. but the sugar break\s fast
I would love to see the macro needs and AAs needs for an elite athlete who trains 2-3x a day. Additionally, what the insights says for RMR match requirements to mitigate metabolic syndromes. There’s always so much contradictory advice when it comes to longevity vs athletic performance. We often see long term cardiovascular disease developed in elite athletes. Finding the fine line balance in diet and supplementation that allows oxidative stress management, cellular recovery without sacrificing performance. Often we, the athletes, live on a very high protein diet. Where it’s 1+ grams protein/1lbs body weight. Massive difference from the 1g/kg lean muscle mass. Really appreciate your time and thoughts. I’ve found your channel very educational.
@oolala53
Жыл бұрын
As has been said, living a life to become or continue to be an athlete is off and actually at odds with a long health span, so I don’t think it’s something that wellness messiah spends a lot of time on. He has even said that the average person has an advantage, and not having to try to improve athletic performance all the time and his inference is that it’s actually a distraction. There’s been some studies on lifespan of athletes, but if you also look at the information on long lived cultures, they are active for their lives, but they don’t do a lot of pushing themselves for long hours every day. There are some channels out there of people who have a very different point of you on this and think that higher protein amounts and working for strength even more than aerobic ability does lead to a long life. Maybe you have heard of Layne Norton or Dr. Gabrielle Lyon, both students of Donald K. Layman. I don’t know what these people think about the whole M tour issue, which I am, assuming is the one that leads other researchers to think that low protein diets are better for long-term health. Best of luck to you and your endeavors.
@KenNYinternational
6 ай бұрын
My best friend is a Brazilian jiu jitsu black belt that has actually fought on espn and hes been a vegan for years and doesnt even eat imitation meat so it’s definitely possible
what about L-Citruline? Are the amino acids to high in supplement form?
I am using this dite to lower my sugar levels and it do works !💫 my question is what about the tuna 🍣 & nori paper can i have it like 2/3 times a week!!? And what about drinks like green tea and Herbal tea of all kinds is it ok every day ?!
Thanks a lot for so Good healthy information!/SemiVegetarian
Given sarcopenia and the poorer absorption of nutrients with age, I wonder if the protein intake should increase with age?
@WellnessMessiah
Жыл бұрын
Hi Steve, you're correct. in the middle of this video I speak (probably too little) about this: kzread.info/dash/bejne/oGyMuLOdZpnMlJs.html Some doctors claim to increase by 20% (on my formula inside that link), but I think the tracking lean mass I mentioned in the video is best.
I'm 59 and pure carnivore. I feel great!
Excellent info, but anyone over 60 needs more protein, not less. Studies show if you are younger, you benefit from less, but as you age, you need more protein to sustain muscle mass.
@WellnessMessiah
Жыл бұрын
Yes, you're right Frances, especially over 65- or 70. I think I mentioned that in this video, didn't I?
@phoenixgirl11
Жыл бұрын
I totally agree with you. Once you get in your 60s you definitely need more protein to maintain muscle. As we age we loose muscle at a fast rate. If you don’t increase your protein you will practically waste away. I’ve seen older women that had no muscle tone and a fall will break just about every bone in their bodies. At that age is not longevity is quality of life. Do you want to live a couple more years in a nursing home or you want to live those years being active and enjoy life. I’ll pick the later.
@monnoo8221
Жыл бұрын
The whole aging argument is crap. It goes like this: they compare young Y and old O under different conditions A and B, If then OB is doing as good as Y it is concluded that B is necessary. Yet, the baseline is taken from a detrimentally aged population, defined as norm, yet NOT being representative at all, for what would objectively be good. What actually WOULD BE good: nobody knows. There are educated guesses, at most. However, if your biological age is much less than the nominal age, say 40 against 60, and you actually ARE healthy, it would be a mistake to conclude that you would need more protein, just for the reason that nominally you are 60. Too much protein makes sick, and hence is a self-fulfilling prophecy. The argument is circular. if however you are NOT healthy then first improve your general condition: fasting, I.F, exercising, keeping inflammation in check = supplement 6 mo with GlycNAC.... and the implement a on\off balanced approach for mtor and ampk.
NAC and Glycine, good topics
I dont understand why you are quoting David Sinclair. He just said animal foods are the worst food for longevity?
@WellnessMessiah
Жыл бұрын
Hi Ellen how are you? I'm not sure what you mean. I believed referred to his fish study, as quoting him. Fish are animals too, so I refer to that and said fish. The whole purpose is to view foods as specific individual composition and impact on longevity, instead of grouping them as animal vs plant. We need to get very specific.
@AL_THOMAS_777
Жыл бұрын
Ever visited a pathologist microsoping meat for poisonous substances and antibiotics ?
I learned more health information from Rimon than most others on KZread.
@WellnessMessiah
Жыл бұрын
Thank you Felicisimo, you're very kind !
This was great information. Thank you. Now if i can just start liking sardines.
Hi. what about shrimp and such?
I rarely got out In sunlight, what do you think should I take vitamin d3 + k2 which I have everyday or every other day also omega 3 for best benefits.
@WellnessMessiah
Жыл бұрын
Hi ichika I'll do video in the future on these. Sunlight has other benefits besides vitamin D, try to get 20 minutes at least every day if you can. "What do you think should I take vitamin d3 + k2" - wasn't sure what you meant. Omega 3 is an everyday supplement.
@ichikakuroki1716
Жыл бұрын
@@WellnessMessiah I mean, I remember when I started taking Omega 3 and Vitamin d3 for first 5-6 days I would see after taking the medicine twice a day every time I would feel to got to bathroom, I felt my guts were cleaning or something, my hair also seemed falling less, kind of felt thick and strong, but then later as the days goes by, It was no longer the same, and then after watching your video In which you said, some supplements like resveratrol should be taken every day instead of everyday due to beneficial clinical data from David Sinclair, so I thought could It be, I should take omega 3 or "Vitamin d3 + k2" not every day for them to work properly!!! Just confused whether It's omega 3 or Vitamin d3 that was causing pressure to go to bathroom due to food digesting properly.
Hi! how much L-arginine is the max amount per day? also, I'm a student and I'd like a consultation with you if possible, I'm trying to figure out the best nutrition plan for myself
@WellnessMessiah
Жыл бұрын
Hi Your Evilness, Since L-arginine isn't needed by your body, the lower the better. It's pure evil. Send an email to wellnessmessiah at gmail com, although, it may take some time, at least you'l be registered when things open up.
Its very confusing dr Sinclair insist vegetarian and dr berg insist keto. I was vegetarian but just started eggs and butter. Dont know whats what
@WellnessMessiah
Жыл бұрын
Hey sairandhree. I understand your point, it's confusing. Sinclair is against fat a bit because he used it in his lab in a toxic way, which can help you understand his position. Here, I tried to show that you can design whatever diet that makes you feel great and energized yet preserve your youthfulness by targeting mTOR. And being accurate with the amount of the foods that you love. There is no point in living longer if you are not in love with your lifestyle ☺
@sairandhreefilms4331
Жыл бұрын
@@WellnessMessiah i understand but what you think of eggs, butter ? Plenty,Everyday or moderate ? Not everyone understands mTOR
@WellnessMessiah
Жыл бұрын
@@sairandhreefilms4331 The truth is that any food needs to look up in the greater view of the diet, because carbs and protein can change how fat works. Sinclair is against fat a bit because he used it in his lab in a toxic way, which can help you understand his position. Generally speaking, I'm very pro eggs (unless highly oxidized, deep frying, brown yolk). Butter - it depends if your body can burn it, which depends on your entire diet. But it is good fat, especially from grass-fed cows. It's different from red meat fat which is more toxic, as it is designed to nourish babies, not just be storage of fat with agricultural toxins.
@sairandhreefilms4331
Жыл бұрын
@@WellnessMessiah thanks I think moderate eggs and butter is fine with vegetarian diet 😊👍
@AL_THOMAS_777
Жыл бұрын
Please dont stress yourself too much. Eggs and butter are quite innocent food. Just dont eat em daily a n d . . . . strictly ORGANIC !!!
How much protein per body weight for longevity purposes though? So confusing …
I hate click baiters who use a noted expert to ge you to click then they espouse their "expertise."
Your English is good
Can someone tell me please if peanut butter is also bad for our health, the same as seed oils?
Fish is good compared to what? As it is a package including both good and bad components, it would likely be better to just use the good components which are basically B12 and omega3. This way you will avoid the saturated fat, the cholesterol and the bioaccumulated toxins.
@Tutokoman
Жыл бұрын
Cholesterol and saturated fat aren't necessarily bad.
@carinaekstrom1
Жыл бұрын
@@Tutokoman It is if you get too much.
@Another_Revert
9 ай бұрын
@@carinaekstrom1nope
Great content but what on earth is that loud music in the background. I found it a challenge to stay with your video because of the music. Would you please reconsider at least turning down the volume so one can cozy up and enjoy the great content. Thanks.
@WellnessMessiah
Жыл бұрын
Thank you Billie for your idea. Are you referring to the section change music, beginning or end?
@gro16
Жыл бұрын
@@WellnessMessiah starting at 3:30 point in the video - It highly competes with the info you are about to give us. It stops and then again later in the second half of the video. It seems that whenever you are about to go over the breakdown or the lowdown of things the music wants to take over.
Great information! Is there any life worth living left if you stick to these strict rules? Just eat your healthy food and fast once in a while and let God do the rest.
@WellnessMessiah
Жыл бұрын
How are you Jay? Yes, as you said, the whole idea is giving leeway and eat the variety of foods that suits your perfect lifestyle :)
How to build muscle in the gym with such low protein?
There's no mention of fruit.are we just supposed to eat any kind of fruit?😊
All right, your comment at around 9:45 minute mark. You forgot to mention that only if the association is causal. Big difference. Fallacy of this type of logic is that you’re using the number as a fact, when the researchers themselves are cautious by clearly stating the caveat upfront.
I think it’s interesting that I believe recently David Sinclair said that he has stopped eating any fish as well as other animal flesh. I don’t know why he thinks that’s a better idea given his reporting on this study.
There are many people like you who only do one thing , and that is to be critics of the creation of others I find those people in every area of life from religion to science . Ironically most of them do not create anything, only say negative thing about those who are pioneer in any fields.
Hi Rmon, I will listen carefully and hope you have an diet option for 65 +plus people.Thanks Rimon Because of Dr David ,I’ve & my family left eating red meat but once a month enjoy eating duck meat or red meat. . Fish & it's products ,I eat nearly 5 times. Plant products have so many Chemicals in it. How will these plant products make our lives longer. Thank you Rimon. I trust your videos👏👏👏 💅✨💫🌟
@pastamandjinka
Жыл бұрын
Organic plant foods are low on chemicals.
@matthewhunter6421
Жыл бұрын
@@pastamandjinka lol, no they're not,.and naturally they're full of chemicals of their own. Google how many naturally occurring carcinogens are in your favorite vegetables
Dairy products?
@WellnessMessiah
Жыл бұрын
HI Angelica. In the context of mTOR (longevity) 1. You need to look at the package and count the protein. 2. Mik has 4 components: - Sugar - bad for longevity. Butter, cheese, don't have a problem here - Butter - good, won't affect mTOR - Whey & casein protein - have good stimulation on mTOR. Suggest limitig to 40% of total daily protein consumption. The most important thing is to avoid eating too much protein, once a week on intense exercise days is fine.
The good for body is that 80-90 % of protein is from meat , eggs and dairy-produce !
So no Leucine? We need mtor to build muscle though.. hmm so we have to be weak and fragile to live longer?
Follow Satvic diet from Yoga India
I am a healthy,fit and active 75+ year old. Good blood pressure not diabetic. I eat meat at least twice a day. Is it to late to change my diet or am i destined to die young.
@zayd7282
6 ай бұрын
LOL good sarcasm. You will not die young even if you wanted to. Bless u.
You didn't mention soy and other legumes, did you?
@WellnessMessiah
Жыл бұрын
Hey Otto . Good question - I did mentioned legumes shortly, as high in l-arginine, moderate in essential amino acids. Carb content varies based on type of legume. I can tell you also, you absorbed 70% of protein in them.
does this apply to all human races ?
I heard that daily intake of proteins is per kg :D and you use constant for an adult (even without splitting it into men and women), not good, but rest is ok
Do you accept the research by an organization that is very anti-meat up front? Doesn't it seem that they might be biased right out of the gate?
Sinclair looked like he was 40 when he was 40. Sinclair looks like he is 40 in his fifties.
What happened to David Sinclair?
Eating 60-70% of animal protein does not seem to coincide with what David Sinclair says..
I don't eat meat or fish and I am fine
The music is annoying
65g protein?? Sarcopena here we come. This diet might be ok for women. How about a man who wants to look and feel strong and masculine.
Dr Grundy claims vegetables are bad for you.
Non vegetarians, 1. Okay, who paid for this? Why am I suspicious of such 'data' ? Lamb chops! I have been eating food for seven decades, and haven't died at all.
@WellnessMessiah
Жыл бұрын
Hi Chris which data do you mean? The processed vs unprocessed study I showed or Sinclair's study? Let's keep you alive for another century :)
@AL_THOMAS_777
Жыл бұрын
Well Christopher, you´re 100% right since especially l a m b chops are quite innocent ! THIS meat does n o t contain antibiotics and other undesirable substances !!
I don't understand why you are presenting the study that pesco-vegetarians, vegetarians and vegans live longer and than shortly after that you say that red meat boosts longevity. Red meat was evaluated by the WHO / IARC as probably carcinogenic to humans - I just don't understand why everyone is promoting the daily consumption of it.
@WellnessMessiah
Жыл бұрын
Hi Michael, I understand your point. Where did I say red meat boosts longevity? Feel free to put here the time. I analyzed the amino acid content of different foods and their impact on mTOR. I suggested limiting to 30%-40% max of protein requirement if you eat red meat. If anything, I showed that processed meat increases death and a high intake of red meat can activate mTOR. Both are the opposite of boosting longevity.
@AL_THOMAS_777
Жыл бұрын
So TRUE Michael, especially since exatly t h i s meat contains sooooooooo many undesirable and dangerous substances . . . and organic red meat iis unaffordable . . .
@debstayblessed9549
Жыл бұрын
@@WellnessMessiah would you consider having dr Greger on your show. he presents the science of the deleterious effects of eating fish for health and longevity.
@monnoo8221
Жыл бұрын
@@debstayblessed9549 yep, just forget about him (Greger)
Can someone stop the annoying background music. It’s so stupid
There's no serious study about the health of meat
🥩🚫
This food is cheap and is garnished with so many spices and gravies to mask the quality. One meal was turkey mac and cheese misleading title it was dog food with pasta and canned peas and carrots.
Fish IS meat!
If you keep your insulin down, then mTor goes up then comes down quickly, if your insulin remains high then mTor stays high longer, read Porfessor Ben Bikmen, the key is to AVOID starchy refinded carbs. ie sugar and carbs that convert rapidly into sugar. Protein is absolutely essential along with fats.
DO NOT WASTE YOUR MONEY IT'S GARBAGE FOOD.
Shame on you Sinclair I bet you wouldn't eat this terrible food.
Why would i take any of these foods when i can get all of the same plus more macro and micro nutrients from animal meat and organs? In addition, vegatables and seeds contain defense chemicals and also have poor bioavailability
@cbh2409
Жыл бұрын
it's the defense chemicals in plants that in part aid longevity in humans. Read his book and he talks all about that.
i dont trust david sinclair
@owensheasbyfitness
Жыл бұрын
why?
Жыл бұрын
Take what you need that is all.. You dont need emotional implication. And if you can give a little bit more than Sinclair, give it.
@monnoo8221
Жыл бұрын
he is completely transparent in saying what he knows, anyone knows, or he or anyone else does not or could not know. And fact is he did an absolute great work in his Lab together with his group... meaning that he can think and is intelligent.... but probably its too complicated for you