Cynthia Kenyon (UCSF) Part 1: Genes that Control Aging
Ғылым және технология
www.ibiology.org/development-...
Once it was thought that aging was just a random and haphazard process. Instead, the rate of aging turns out to be subject to regulation by transcription factors that respond to hormones and other signals. In the nematode C. elegans, in which many key discoveries about aging were first made, the aging process is subject to regulation by food intake, sensory perception, and signals from the reproductive system. Changing genes and cells that affect aging can lengthen lifespan by six fold, and can also delay age-related disease, such as the growth of tumors.
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"It's like a miracle, but it's not a miracle--it's science." Brilliant, amazing woman. So much respect for her and her research.
@stellarblur
3 жыл бұрын
so does growth hormone increase Igf1, because fasting increases growth hormone?
I've been fascinated by this since hearing a snippet of a programme on BBC Radio 4 a couple of years ago. I can by no means profess to understand all the content here but the delivery and passion for the subject makes me want to understand more. Thank you for posting this.
She was so far ahead of everyone.
Refreshing and enlightening information. Thank you.
Great video! A nice introduction to this active area of research :)
@monineh In theory, yes, if they limit glucose intake. However, there may be associated deficiencies which might affect that outcome.
Laura deming sent me here
Rod Hayes sent me here
Great learning from this intelligent scientist. Role model❤️
this is the kind of video you'd see in a zombie movie
QUESTION > I NEED TO KNOW WHICH MASTERS COURSE IS BEST SUITED FOR DOING RESEARCH IN AGEING PS > I am 20 y/o from India, Currently doing my Bachelors in Biotechnology. I am very interested in Ageing and Science. and looking for guidance from the experts themselves Kindly Do reply
Fruit flies rock!!!! :)
fascinating, but wouldn't it mean that type 1 diabetics who control their condition well should age more slowly and live longer?
@aaronsilver-pell411
3 жыл бұрын
I'm not 100% certain whether insulin-like growth factor 1 is always tightly coupled to insulin itself. it's "insulin-like" rather than insulin. Also, type 1 diabetics have to inject insulin in themselves all the time to survive so the body is not actually free from insulin. one broader point is that it seems as if nutrient clearance is an important factor in lifespan is high lipids and high glucose in the blood are associated with early mortality. Now whether this means that the body is just in distress and this is a sympton and not a cause is not completely clear, but the fact that so many people who live to 100 have mutations with fat-clearing enzymes in the blood does indicate that too many nutrients in the blood is a real problem. So no, you would not suspect that type 1 diabetics would live longer.
so does growth hormone increase Igf1? because fasting increases growth hormone. but calorie restriction increases lifespan
@aaronsilver-pell411
3 жыл бұрын
yes GH stimulates IGF1.
, - this is how c.elegans looks like
Daibetic patient live longer?
@ScientiaVeritasEtLux up with darwin, crick and hawkins? errm its obvious you have a crush on her!
@datzfast So basically, get your Vitamin C. I remember before when I didnt use to get enough. Now I feel much better than I ever had in years.
???
I Send you a message with comens. Virgilio Victoria-Troncoso Md PhD
@teewoods I'd marry her in a second! And we'd be happy together living for a few hundred years.
Well... something is wrong; just look at her appearance.