CRISPR and the Future of Human Evolution

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Part 4 of our special series on Human Ancestry. Watch it all ►► bit.ly/OKTBSHuman
Watch Mutant Menu on BrainCraft: • MUTANT MENU | The Et...
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In part 4 of our special series on human ancestry and evolution, we look into the future. Now that genetic engineering tools like CRISPR allow us to edit our genes, how will that impact human evolution going forward? Are designer babies or eugenics around the corner? Welcome to a world of nonrandom mutation and unnatural selection.
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REFERENCES:
WHO fact sheet on obesity risks and death vs underweight: www.who.int/mediacentre/factsh...
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., & Charpentier, E. (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science, 337(6096), 816-821.
Knoepfler, P. (2015). GMO Sapiens: the life-changing science of designer babies. World Scientific.
Enriquez, J., & Gullans, S. (2015). Evolving Ourselves. Oneworld Publications.
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It’s Okay To Be Smart is hosted by Joe Hanson, Ph.D.
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Writer: Joe Hanson
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Пікірлер: 1 800

  • @besmart
    @besmart7 жыл бұрын

    Enjoy part 4 of our human ancestry series! Here's a look at the future. Do you think CRISPR will change human evolution?

  • @Hunt3rseeker

    @Hunt3rseeker

    7 жыл бұрын

    This is the point where we go from animals, human beings, to something else. What, I do not know, but something grand.

  • @TheDigitalZero

    @TheDigitalZero

    7 жыл бұрын

    To xenomorphs? ;)

  • @ericvulgate

    @ericvulgate

    7 жыл бұрын

    we will still be human. evolution doesn't make things change into 'something else'- whatever we might become we will still be human, just as we are still mammals, and apes, and chordates.

  • @TylerMatthewHarris

    @TylerMatthewHarris

    7 жыл бұрын

    It's Okay To Be Smart memetics will become even more relevant if this happens.

  • @BlueImation

    @BlueImation

    7 жыл бұрын

    It's Okay To Be Smart hello!🔈

  • @AN1MATEK
    @AN1MATEK6 жыл бұрын

    There's definitely some top secret humans experiments going in some shady nation, I don't think everybody is passing out on being pioneer.

  • @gregoriikatastrov7472

    @gregoriikatastrov7472

    5 жыл бұрын

    It's not even top secret. China is already experimenting and dont give a fck what other nations thinks about it ;) (yeah i know its an old comment and you probably already know that, you are among a "smart people", as Joe calls us after all.)

  • @Ivan.A.Churlyuski

    @Ivan.A.Churlyuski

    3 жыл бұрын

    The year before your comment the US military agency DARPA invested $100m in an CRISPR program to extinct certain genes.

  • @The231447LucidDevTeam

    @The231447LucidDevTeam

    3 жыл бұрын

    I think we should just research it

  • @safetydave720

    @safetydave720

    2 жыл бұрын

    Wuhan China, and Area 51

  • @africanhistory

    @africanhistory

    2 жыл бұрын

    Israel

  • @Asama7
    @Asama77 жыл бұрын

    "I like to order one muscular baby with two blue eyes and blond hair". Hospitals in the future

  • @hellpwnage6665

    @hellpwnage6665

    7 жыл бұрын

    osama al-enzi aka a super saiyan

  • @aegonii8471

    @aegonii8471

    7 жыл бұрын

    QuerkyBren Your mom would be happy too. The son she always wanted 😄.

  • @leaveme3559

    @leaveme3559

    6 жыл бұрын

    Looks like everyone in the future will be tall blue eyed muscular....and quite possibly dark and mysterious

  • @BlueFrenzy

    @BlueFrenzy

    6 жыл бұрын

    I rise the stakes: "I like to order one baby with laser in the eyes and wireless brain telepathy".

  • @ILNSuryaChandra

    @ILNSuryaChandra

    5 жыл бұрын

    @@BlueFrenzy I will order a baby who can levitate, teleport, shoot lasers from eyes, shape shift etc..jack jack

  • @amcghie7
    @amcghie77 жыл бұрын

    I believe this comes to the old analogy "Science provides the keys, but it is humanity that decides what doors to open." Technologies like these are incredible developments in science, however with these developments they can be both used for morally good and bad things - similar to the development of nuclear technologies 80 years ago. We need to be careful here in how this is used.

  • @carlapatriciarodriguesbarr8322

    @carlapatriciarodriguesbarr8322

    5 жыл бұрын

    Poderiam passar este vidio para português. Gostaria de saber Est á técnicas para curar doenças .

  • @fluffycatgaming5775

    @fluffycatgaming5775

    3 жыл бұрын

    I agree

  • @tuele4302

    @tuele4302

    3 жыл бұрын

    And don't forget moral standards change from person to person, society to society, historical era to historical era.

  • @maxmitchell8180

    @maxmitchell8180

    3 жыл бұрын

    @@tuele4302 this is the most ethical way of implementing eugenics :)

  • @prapanthebachelorette6803

    @prapanthebachelorette6803

    2 жыл бұрын

    Agree

  • @menohaveaname
    @menohaveaname7 жыл бұрын

    "Dad, I can't believe you didn't give me big eyes and a cute dimples. All the other dads gave their daughters cute dimples..."

  • @Mochi_Kiti

    @Mochi_Kiti

    3 жыл бұрын

    "Well honey, we didn't want you to look like all those *other kids* we wanted you to be special."

  • @barnaliadhikary9421

    @barnaliadhikary9421

    3 жыл бұрын

    My mom gave me fair skin complexion & small nose 🤗

  • @unkind6070

    @unkind6070

    Жыл бұрын

    ​@@barnaliadhikary9421 what do you mean fair skin? All skin colors are amazing

  • @KaiserMattTygore927
    @KaiserMattTygore9277 жыл бұрын

    "It will never ever ever lead to superpowers" well not with THAT attitude.

  • @Mangofretchen
    @Mangofretchen7 жыл бұрын

    "I'll sell my inventions so that everyone can be superheroes. *Everyone* can be super! And when everyone's super... [laughs maniacally] *no one* will be." -Syndrome

  • @dommyWommy82

    @dommyWommy82

    3 жыл бұрын

    Perfect

  • @everysubonepushup

    @everysubonepushup

    2 жыл бұрын

    I was just watching incredibles

  • @smrutishikharath3025

    @smrutishikharath3025

    2 жыл бұрын

    👏🏻👏🏻👏🏻👏🏻😤😤😤

  • @treyrandolph4720
    @treyrandolph47203 жыл бұрын

    in the immortal words of Dr. Ian: "Your scientists were so preoccupied with whether or not they could, they didn’t stop to think if they should."

  • @diablo.the.cheater

    @diablo.the.cheater

    2 жыл бұрын

    Scientists should not stop to think if they should, because they have better thing to think about, the ones to think about those should or shouldn't are not scientist but the phylisophers.

  • @silentwatching9069

    @silentwatching9069

    2 ай бұрын

    "Live will find a Way." and it might surprise us. If we try to improve what Nature selected to be best in a Million years Long Experiment - we might get a nasty surprise.

  • @TimwiTerby
    @TimwiTerby6 жыл бұрын

    Instead of “unnatural selection”, I feel you should have called it “artificial selection”, which is more to the point. The word “unnatural” has negative connotations and cultural baggage.

  • @EduardoHerrera-fr6bd

    @EduardoHerrera-fr6bd

    4 жыл бұрын

    and also arbitrary mutation, not 'random' because it is not entirely random

  • @ritwikreddy5670

    @ritwikreddy5670

    4 жыл бұрын

    @@EduardoHerrera-fr6bd mutation is entirely random

  • @ritwikreddy5670

    @ritwikreddy5670

    4 жыл бұрын

    @@EduardoHerrera-fr6bd mutation is like throwing a dice. When or where the dice is thrown is not random, but the end product is completely random. Technically nothing is entirely random but I think you get my point.

  • @EduardoHerrera-fr6bd

    @EduardoHerrera-fr6bd

    4 жыл бұрын

    @@ritwikreddy5670 yeah, i guess my comment was implicitly denying that but i didn't mean that. as a worldbuilder, this topic is very important for me

  • @paradox9265

    @paradox9265

    3 жыл бұрын

    Timwi Heizmann it is pretty negative though... like ordering a more good-looking baby or something?? What u want, a robot?

  • @ahmednagy7571
    @ahmednagy75717 жыл бұрын

    I watched already in kurzesgat but I will still watch it in your voice

  • @aristerosgiatros8742

    @aristerosgiatros8742

    7 жыл бұрын

    Ahmed Nagy same bruh

  • @MegaMGstudios

    @MegaMGstudios

    7 жыл бұрын

    Ahmed Nagy both are amazing, i need to watch both

  • @scrollogy5847

    @scrollogy5847

    3 жыл бұрын

    Same

  • @koko-oz7jf

    @koko-oz7jf

    3 жыл бұрын

    OMG IS IT HIM????

  • @chatgptnewslive2023
    @chatgptnewslive20237 жыл бұрын

    Mice with human jeans. 😂

  • @Borderlands808
    @Borderlands8085 жыл бұрын

    I just want to breath underwater. Give me gills!!!

  • @Ardkun00

    @Ardkun00

    2 жыл бұрын

    You can choose argonian as your race.

  • @arrghh0
    @arrghh07 жыл бұрын

    Thank you so much for these. You're sincerely an awesome human being for what you do. It's channels like this that have motivated me, at age 27, to go back to college and actually go for a Microbiology/Molecular Biology major, so I can do my part to help advance things like this. All the kudos to you, sir.

  • @Jamess0090

    @Jamess0090

    Жыл бұрын

    And how’s life going five years later? Did you successfully completed the degree?

  • @bridgettewalker3739
    @bridgettewalker37396 жыл бұрын

    I learned about cut and splice technology in AP bio this year, it was really interesting! It's definitely something cool to read into.

  • @tonywooten596

    @tonywooten596

    3 жыл бұрын

    I want to find out why it's called palindromic

  • @aditpatel2474
    @aditpatel24747 жыл бұрын

    We need to make Crispr make trees take in large amounts of carbon dioxide

  • @l.tc.5032

    @l.tc.5032

    6 жыл бұрын

    Adit Patel it's literally the easiest way to fix climate change. I have no idea why we don't do it now.

  • @mcgrudo

    @mcgrudo

    6 жыл бұрын

    It could have a dangerous run away effect like expelling too much oxygen. Insects would be the size of trucks if the oxygen level rose to a certain level :O

  • @drizzelkun

    @drizzelkun

    5 жыл бұрын

    how do u imagine trees work? like they just suck up all the co2 and then everything is fine ? nani?

  • @Jan-hu1hk

    @Jan-hu1hk

    4 жыл бұрын

    but trees and plants need co2, so it wont be wise to take out too much

  • @k1esther1w
    @k1esther1w7 жыл бұрын

    I found this channel about a week ago and watched several of your videos. Although I do not understand everything I am enjoying learning and watching. Thanks for the videos, keep them coming.

  • @60secondsuccess39
    @60secondsuccess397 жыл бұрын

    I love the possibilities that this unveils. Curing disease? Curing malignant mutation? All of this is great, I just worry about the eugenic implications of this. Does anybody have any similar ideas?

  • @josefernandez1077

    @josefernandez1077

    7 жыл бұрын

    I think that this is a slippery slope. In the short run, the curing of disease is fantastic. But in the long run, the potential to modify somatic appearance is quite frightening. Edit: I clicked off onto your channel and I was pleasantly surprised.

  • @Rowow

    @Rowow

    7 жыл бұрын

    So selecting sperm from specific males for specific traits in a sperm bank is fine but CRISPR is not? So getting a abortion due to health defects or other issues that can be seen during embryo development is fine by CRISPR is not? So on and so forth. The only different between the two is that one is slightly more "natural" then the other. The outcome is the same or better. You just have a hypocritical view point and fail to understand the failure in your logic rather then opening your mind to the countless lives and humanities progression in society that will happen.

  • @morgangreen2526

    @morgangreen2526

    7 жыл бұрын

    60 Second Success Another worry for me is overpopulation. In light of that, eugenics in itself does not worry me much.

  • @morgangreen2526

    @morgangreen2526

    7 жыл бұрын

    Humans are prone to fucking up in the vain of making *our* world more comfortable; Human genetic selection has the potential to be one of the worst fuck ups.

  • @60secondsuccess39

    @60secondsuccess39

    7 жыл бұрын

    robert karas I think there are two separate arguments here. The first of which we agree on; using CRISPR and other genetic marker detection systems to deal with potential health defects, is good. The second question is more morally ambiguous. I'm worried about the potential class divide that CRISPR could create. We are approaching a time, where through the means of a (potentially) expensive embryonic procedure, it is possible to create physically superior humans. Who's to say that this doesn't create a divide in the human race? Genetically engineered vs. non-genetically engineered. I think that this divide is already coming in terms of physical technological enhancements. These procedures are going to create an objective divide between classes. This is conflict theory on steroids. This is how anarchy is formed.

  • @superj1e2z6
    @superj1e2z67 жыл бұрын

    The question is can CRISPR make crispier chicken skin?

  • @emperortunalirius2753

    @emperortunalirius2753

    7 жыл бұрын

    superj1e2z6 yes it can

  • @thewitheringproduction1761

    @thewitheringproduction1761

    7 жыл бұрын

    yes it can.

  • @bluedwarf1699

    @bluedwarf1699

    7 жыл бұрын

    superj1e2z6 hopefully not while the chicken is alive though.

  • @jordanmoser7908

    @jordanmoser7908

    7 жыл бұрын

    +Gotrek Gurnisson that'd be fucked up 😂 you'd have a bunch of people running around chasing crispy chickens 😂 could u imagine!

  • @SchmegmaOnToast

    @SchmegmaOnToast

    7 жыл бұрын

    who knows, editing chicken genes might end up with cripy chicken, instead.

  • @marianghobreialmakeup
    @marianghobreialmakeup5 жыл бұрын

    I loveeeee your channel you opened my eyes to alot of things i didn't know before thank you so much

  • @seanclarkdesign
    @seanclarkdesign7 жыл бұрын

    This was one of the most epic videos you've done guys. Thank you so much for what you do.

  • @radio_static6222
    @radio_static62227 жыл бұрын

    That designer-baby thing reminded me a lot of the movie Gattaca

  • @ericvulgate

    @ericvulgate

    7 жыл бұрын

    that's our near future.

  • @axue4248

    @axue4248

    7 жыл бұрын

    Ehhhh... tbf the Gattaca world didnt seem like that bad of a place to live in given that ur a genetically modified human. I mean I would personally like to have a child while not having the fear of passing on some of my negative traits to my child. Though I can see a massive issue with a lack of genetic diversity as everyone just follows a 'template' for the ideal person, sorta like how Korean beauty standards have lead to an ideal face that people have cosmetic surgery to attain.

  • @whydoievenbothertoputthish2199

    @whydoievenbothertoputthish2199

    7 жыл бұрын

    i heared they could scan a baby in the woumb to check if it has an extra chromosone so they can remove it so the whole designer baby is closer than you think

  • @JoyStar

    @JoyStar

    7 жыл бұрын

    Never heard of that movie, would you recommend it?

  • @georgiajaw

    @georgiajaw

    7 жыл бұрын

    JoyStar Yes. Gattaca is a really good movie. Kind of sad too.

  • @654pedro123
    @654pedro1237 жыл бұрын

    Humans already have the power to shape their children's lives for good and bad. How is giving those children good traits bad for them?

  • @andrewlamore72

    @andrewlamore72

    7 жыл бұрын

    It's not so much about giving children what we think are good traits, but instead it's about designing someone for a specific task. For example, with crispr we could breed babies that are stronger than everyone else, but force them into jobs as laborers or soldiers. What most people are afraid of is the rich using their money to create a breed of humans naturally smarter than everyone else, thus putting humans into two camps: dumb and poor or smart and rich, and there wouldn't be anything the dumb and poor people could do about it.

  • @user-cw9lf3gl6x

    @user-cw9lf3gl6x

    7 жыл бұрын

    654pedro123 "Hey, look, it's trending now to have babies with smooth-pale skin and blue eyes, let's design our baby that way!" And long behold every baby that generation will look the same. Good luck using pheromones only to find your companion.

  • @ESPmrBrough

    @ESPmrBrough

    7 жыл бұрын

    the only people who think fat people are beautiful are fat people in denial, and fetishists.

  • @vinny5638

    @vinny5638

    7 жыл бұрын

    +Mr Blank My parents already molded my life after someone else wanting me to be a theological professor or pastor. BILLIONS of humans lives are predetermined in HUNDREDS of ways by governments, arranged marriages, etc and almost NONE of them are positive. Now we have a way to create babies with better traits and you think its bad because of a subjective view of perfection? Dude what?

  • @castorpolux9050

    @castorpolux9050

    7 жыл бұрын

    "good traits"

  • @MrUmbraya
    @MrUmbraya7 жыл бұрын

    Best video yet. Very easy to understand and a clear presentation of ethics without taking sides. Keep it up!

  • @zertilus
    @zertilus7 жыл бұрын

    So much work gets put into these videos, good stuff guys. Thanks so much for the informative, entertaining content!

  • @Master_Therion
    @Master_Therion7 жыл бұрын

    BUT HEY, IT'S JUST A THEORY, A *GENE* THEORY.

  • @hussainattai4638

    @hussainattai4638

    7 жыл бұрын

    Thanks for watching!!

  • @TUSH4R451

    @TUSH4R451

    7 жыл бұрын

    Thanks for watching!

  • @yahschild9348

    @yahschild9348

    7 жыл бұрын

    Master Therion how is this evolving of any sort?

  • @mistermccoolface1361

    @mistermccoolface1361

    7 жыл бұрын

    Master Therion haha! i get it! *tightens noose*

  • @martinstip9

    @martinstip9

    7 жыл бұрын

    it's not a theory it's real

  • @PikaPetey
    @PikaPetey7 жыл бұрын

    furries rejoice when this technology becomes mainstream. or the world becomes G A T A C A

  • @eternalbastion7454

    @eternalbastion7454

    7 жыл бұрын

    Pikapetey Animations yiffers' rejoice.... 😁😁😁😁😁😁

  • @LimeyLassen

    @LimeyLassen

    7 жыл бұрын

    CATTACA

  • @cauchyhorizon5983

    @cauchyhorizon5983

    7 жыл бұрын

    I gotcha covered, Pikapetey. I'm already working on a wolf/human genome.

  • @eternalbastion7454

    @eternalbastion7454

    7 жыл бұрын

    The Improbable Space it's gonna be Renamon taking the world by storm all over again. 😂😂😂😂

  • @jamesha175

    @jamesha175

    7 жыл бұрын

    human ewok hybrids?

  • @laszlowisniewski
    @laszlowisniewski7 жыл бұрын

    ive read and watched some really technical articles and videos on the CRISPR CAS-9 system and genome editing. this video realllllly breaks it down into digestible chunks! great watch

  • @briethey-them9542
    @briethey-them95424 жыл бұрын

    It was my first day back to school and I guarantee the 4 videos in this series taught me more than I'm going to learn all school year. Definitely subscribers OK no now.

  • @marcos186cy
    @marcos186cy7 жыл бұрын

    2:08 dat pun almost killed me

  • @FZ8Yamaha
    @FZ8Yamaha7 жыл бұрын

    I love how this video gets me excited about the future!

  • @reemeruxd
    @reemeruxd7 жыл бұрын

    Haha the character creation bit was really well done. Nice one guys!

  • @thaikeaugusto4356
    @thaikeaugusto43567 жыл бұрын

    This channel ia simply amazing... Thank you very much for your beautiful work!

  • @chubbsmasterson
    @chubbsmasterson7 жыл бұрын

    0:20 Some...BODY ONCE TOLD ME....

  • @morgangreen2526

    @morgangreen2526

    7 жыл бұрын

    Christopher Luke the world was macaroni...

  • @faze_d4nk775

    @faze_d4nk775

    7 жыл бұрын

    the world is gonna roll me

  • @pizzamandhx

    @pizzamandhx

    7 жыл бұрын

    She was lookin' kinda dumb with her finger and her thumb

  • @faze_d4nk775

    @faze_d4nk775

    7 жыл бұрын

    In the shape of an "L" on her forehead

  • @ObjectsInMotion

    @ObjectsInMotion

    7 жыл бұрын

    Christopher Luke Well the years start coming *and they don't stop coming*

  • @loganhamilton4246
    @loganhamilton42465 жыл бұрын

    Hey, Joe! I've heard this topic come up several times and am very interested in it. I'm just a bit in two minds about the ethics of CRISPR. Could you make a follow - up video on that topic please?? 👍

  • @user-mr7cw8wf9k
    @user-mr7cw8wf9k7 жыл бұрын

    Best KZread Channel out there. Your videos, sir, give me chills!

  • @paigemittelbrunn4621
    @paigemittelbrunn46217 жыл бұрын

    This is such a cool channel!! You make learning super fun. Definitely gonna subscribe!

  • @Garium87
    @Garium877 жыл бұрын

    Most parents don't want a purple-eyed hulk with the IQ of Tesla. Most parents want simply the best for their children and they are smart enough not to go to the extreme. And I don't see the problem if someone who isn't really sick but let's say is bold, or short, or maybe has a rather low IQ, doesn't want his child to have the same kind of problems to deal with. I doubt that the child will blame his parents for changing such obvious, disadvantages. To be able to prevent your child from a disadvantage and then to choose not to, *that* is the morally questionable decision, in my eyes.

  • @redmondokelly2464
    @redmondokelly24647 жыл бұрын

    0:20 You look beautiful

  • @pokemonmaster9593

    @pokemonmaster9593

    7 жыл бұрын

    He made my dream boy.

  • @WarisAmirMohammad

    @WarisAmirMohammad

    7 жыл бұрын

    he looks just like Bart from Simpsons

  • @MrPianoMatt12

    @MrPianoMatt12

    7 жыл бұрын

    From tip to toe, that's a bart

  • @evilmatt91

    @evilmatt91

    7 жыл бұрын

    Looks like Piccolo's mentally challenged cousin

  • @jamiehughes5573

    @jamiehughes5573

    7 жыл бұрын

    Special Needs cannon

  • @MrGuykgk
    @MrGuykgk6 жыл бұрын

    Favourite video so far! Awesome stuff, love the little animations they're hilarious!

  • @billmalcolm4291
    @billmalcolm42917 жыл бұрын

    I could go for a larger, faster prefrontal cortex. Figure that should help improve my higher executive functions. Fewer Ige antibodies would be nice too (thanks for your allergies episode). Love your work IOTBS and PBS!

  • @tarrakis
    @tarrakis7 жыл бұрын

    "What if only the rich can afford to edit genes?" What if? Really? ;)

  • @tuele4302

    @tuele4302

    3 жыл бұрын

    "So what?" is the question. People naturally want the best for their children. If they already choose private schools or fancy extracurricular activities, this seems natural.

  • @tarrakis

    @tarrakis

    3 жыл бұрын

    @@tuele4302 Capitalism at its best. Or worst.

  • @tuele4302

    @tuele4302

    3 жыл бұрын

    @@tarrakis At its best for sure. It is normal and adaptive to pursue the best interest of our children.

  • @tarrakis

    @tarrakis

    3 жыл бұрын

    Of course we are going tu pursue the best interest for our children. But what about people who can't afford it? Eg: Healthcare

  • @tuele4302

    @tuele4302

    3 жыл бұрын

    @@tarrakis What about them? Why should children of a given couple suffer because some parents of other children cannot do certain things? Children deserve the best from their parents.

  • @Kaikaku
    @Kaikaku7 жыл бұрын

    I think it's not a question if we will, cause we will. What is technologically possible, will be tried out sooner or later.

  • @magal.oliveira682
    @magal.oliveira6827 жыл бұрын

    I found this chanel some days ago... now I love it! 😍

  • @InvokingPeace
    @InvokingPeace7 жыл бұрын

    outstanding presentation, really entertaining to watch as well, you're my favourite science-channel at this point

  • @FrustratedBaboon
    @FrustratedBaboon4 жыл бұрын

    Stop my aging so I can help speed up this research. Aging should be taken care of first.

  • @TheNewsDepot
    @TheNewsDepot7 жыл бұрын

    We will. CRISPR is so cheap and easy to use relative to other options that less economically sound countries, like North Korea, will eventually create "super soldiers" and "Super citiznes" to gain an edge over more powerful countries. It's not a matter of if, but when.

  • @MikiDii1
    @MikiDii17 жыл бұрын

    idea channel just made a video about this too! I love it when the pbs channels connect with each other

  • @patriciamartinez1783
    @patriciamartinez17834 жыл бұрын

    This information is really interesting, as a student in the area of biological science, CRISPR is a subject that causes me many questions. As you mentioned, this technique can be used to cure illnesses, however in the wrong hands it could also be used for human edition, getting into a problem with our ethics. It is a topic that will always be in discussion, due to the benefits that we can obtain. Although it sounds like something futuristic, it is something that is happening today.

  • @tjep997
    @tjep9977 жыл бұрын

    Let's do it! Curing all diseases sounds good to me!

  • @marcelloascani
    @marcelloascani7 жыл бұрын

    awesome

  • @I_THE_I

    @I_THE_I

    3 жыл бұрын

    No

  • @tanyag2499

    @tanyag2499

    3 жыл бұрын

    @@I_THE_I ok

  • @sparkers70
    @sparkers707 жыл бұрын

    One of your best videos so far. Fascinating stuff. :)

  • @dkennell998
    @dkennell9987 жыл бұрын

    Best explanation of CRISPR I've seen so far!

  • @CreeepsMind
    @CreeepsMind7 жыл бұрын

    2:10 "Mice with human jeans"

  • @juki0h391
    @juki0h3917 жыл бұрын

    in the near future, two human species will walk among earth , organic humans vs genetically modified humans. going to be interesting which one will win out.

  • @drakan4769

    @drakan4769

    7 жыл бұрын

    don't forget the cyborgs

  • @alaapsarkar

    @alaapsarkar

    7 жыл бұрын

    genetically modified cyborgs also!

  • @aegonii8471

    @aegonii8471

    7 жыл бұрын

    Don't forget the ground people

  • @dannyp2970

    @dannyp2970

    6 жыл бұрын

    and the rat people.

  • @self-crownedroyalty6712

    @self-crownedroyalty6712

    6 жыл бұрын

    But genetically modified humans are organic. I mean everything is modified so i see no difference, except you know one side has more power and control to their own genome.

  • @yawhbrawh6984
    @yawhbrawh69847 жыл бұрын

    this has been done since 2012, but it's amazing to see another break down on it

  • @RhysIsThisGood
    @RhysIsThisGood7 жыл бұрын

    Don't you just love it when he says "STAY CURIOUS."

  • @sciyay
    @sciyay7 жыл бұрын

    That makeover game in real life would be amazing.

  • @starcoreart

    @starcoreart

    7 жыл бұрын

    pefcoy "amazing"? You're joking, right?

  • @vicokhang7178
    @vicokhang71787 жыл бұрын

    I want to CRISPR my male pattern baldness so do other billions people out there.

  • @feynstein1004

    @feynstein1004

    7 жыл бұрын

    As a fellow MPB victim, I agree. But I don't think it's happening anytime soon. Unfortunately.

  • @In_TheMoonlight
    @In_TheMoonlight6 жыл бұрын

    this looks so cool! it would be interesting to see how gene editing is used in the future

  • @sthephaniec
    @sthephaniec7 жыл бұрын

    Loved this video! Great work :)

  • @Elduque40
    @Elduque407 жыл бұрын

    a platypus? Perry the platypus

  • @eternalbastion7454

    @eternalbastion7454

    7 жыл бұрын

    Elduque40 Curse you perry the platypus !!!!😁😁😁😁😁

  • @aristerosgiatros8742

    @aristerosgiatros8742

    7 жыл бұрын

    Elduque40 platypus---- platyPUSSIES

  • @iwatchedtoomuchsaikik8949

    @iwatchedtoomuchsaikik8949

    3 жыл бұрын

    Dr. Doofinsmerts

  • @johnbartholf777
    @johnbartholf7776 жыл бұрын

    Not "if we will," "when we will."

  • @lukaspxixixixixi3626
    @lukaspxixixixixi36267 жыл бұрын

    wow thank you so much joe. I'm planning a biology lesson on crispr/cas for school at the moment and stole a few of your ideas =)

  • @briandang6766
    @briandang67667 жыл бұрын

    Intro was gold

  • @WWZenaDo
    @WWZenaDo7 жыл бұрын

    I have a feeling there may be some unpleasant side effects from selecting appearances based on transient human fads. It's possible that changing everyone's hair to blonde (for example) will bring with it the shortened life span, higher vulnerability to skin cancers & thinner bones that many blondes are prone to.

  • @geiss747
    @geiss7477 жыл бұрын

    so basically people could get near to immortality?

  • @Mochu_s_Junkyard

    @Mochu_s_Junkyard

    4 жыл бұрын

    @Psywriter Pls you clearly dont know what are u talking about @Geisseboeckli Yes, que celular aging is caused by the phisical wear of the telomere that protecs our DNA (as the aglets do in our shoes), something that evolution hasn't fixed because it was REALLY unusual that someone could die due to the problems with an advanced age when... a small cut could kill you before Peniciline. So yes, we will able in a distant future to enlarge Telomeres with CRISPR in form of vacinations or at least that is what the science community thinks, but this could come in a far far time

  • @abhiprakash74999

    @abhiprakash74999

    4 жыл бұрын

    Not crispr alone. But with advances in other fields of biotech , infotech , nanotech , etc . Well cumulatively they could make us immortal

  • @abhiprakash74999

    @abhiprakash74999

    4 жыл бұрын

    @Psywriter well true. We won't be like Superman who almost nothing can kill. We will still die from accidents or violence. But the chances of both can decrease very , very much. Besides I'm too sure about this but I guess if you can create a copy of your mind. An exact copy with memories , etc. U could technically keep it in statis and once u die. Well I guess u could wait a few decades or centuries until u can reload them into a new bod. Yes I'm aware this is all speculation. But I really think that is possible in our lifetime. Or maybe that's just my optimism bias . 😊

  • @dsmerda
    @dsmerda6 жыл бұрын

    Hello, can I ask you, what is the name of the song that you used from APM music library around 4:30 of this video? I cannot find it. Thanks for your time, nice work, by the way.

  • @Felixkeeg
    @Felixkeeg7 жыл бұрын

    I wouldn't mind elongating my life span a little bit. Theres so much to learn, to see and to research.

  • @princekyros
    @princekyros6 жыл бұрын

    Well, I would've wanted to be a blue eyed muscular baby :(

  • @Preuen-zs1fz
    @Preuen-zs1fz6 жыл бұрын

    4:10 "Cancer hunter" feel like calling a cancer hunter when I read KZread comments from creationists

  • @GosiaatjeQui
    @GosiaatjeQui6 жыл бұрын

    OMG! The way you explain this is so funny I'm giggling uncontrollably! 😄 I love it!

  • @Jasmic0137
    @Jasmic01377 жыл бұрын

    The intro was great :D

  • @burdogashi3922
    @burdogashi39227 жыл бұрын

    I wold sat with this technology. Take away life threatening jeans like cancer. But parents get no say in what to make the kid look or act like

  • @melvinpariyadan4884

    @melvinpariyadan4884

    7 жыл бұрын

    i am so scared, all places where i go i see life threatening jeans. lets remove those with CRISPR

  • @Angela-pj5xy

    @Angela-pj5xy

    6 жыл бұрын

    Sometimes life threatening genes and life saving genes are the same genes, just look as sickle cell, it both protects from malaria (still a major global killer) and it causes "genetic disease". This isn't all that simple.

  • @shridharjoshi5602
    @shridharjoshi56027 жыл бұрын

    where is my never on time squad at

  • @christiandevey3898

    @christiandevey3898

    7 жыл бұрын

    Killer Pyjamas that's me in a nutshell

  • @needsomesuga

    @needsomesuga

    6 жыл бұрын

    Killer Pyjamas wow I'm so early

  • @JJJ2_00

    @JJJ2_00

    3 жыл бұрын

    You called?

  • @Ahguang85
    @Ahguang857 жыл бұрын

    the graphics are really neat!

  • @LuisGermanRT
    @LuisGermanRT3 жыл бұрын

    The part of the mice with human jeans really had me 😂

  • @morgangreen2526
    @morgangreen25267 жыл бұрын

    Eugenics?

  • @thewitheringproduction1761

    @thewitheringproduction1761

    7 жыл бұрын

    not really because you aren't killing anyone with bad genes or stopping them from breeding.

  • @morgangreen2526

    @morgangreen2526

    7 жыл бұрын

    the withering production Eugenics is not about elimination of sections of the gene pool. Eugenics is the belief that there are superior and inferior gene expressions in humanity. CRISPR rides on such a belief being true, which is somewhat true.

  • @BlueSun_

    @BlueSun_

    7 жыл бұрын

    "Somewhat true" is the understatement of the year.

  • @Blackmark52

    @Blackmark52

    7 жыл бұрын

    I don't understand why eugenics itself is of any concern. Humanity should be striving to improve itself and considering how fast we are changing our environment -- and may even need to adapt to entirely new environments such as the harshness of space -- evolution just isn't going to cut it. Genome editing techniques may be one of the most important tools we have to ensure the continued existence of humanity. It seems to me that the bad rep of eugenics comes from archaic implementations of times past and primitive understanding of what genetics actually is.

  • @morgangreen2526

    @morgangreen2526

    7 жыл бұрын

    Blackmark52 I am concerned about human error

  • @Sixsince-dd2eu
    @Sixsince-dd2eu7 жыл бұрын

    _"Mice with human jeans."_

  • @RealMikeClements
    @RealMikeClements6 жыл бұрын

    Damnit i came here for one video and I’m still here 3 later haha, great content. Right to the point.

  • @belletran5403
    @belletran54037 жыл бұрын

    I think for this to have a positive impact and little to no unethical use, its use needs to be extremely transparent to the public maybe some government regulation. (also i'm so glad people are becoming aware and this video exist! i remember trying to explain this to people three years ago and they didn't believe it!)

  • @justsomestranger4894
    @justsomestranger48947 жыл бұрын

    How would the people working on CRISPR feel if some parents wanted to select for their future child to have something like deafness instead of against it?

  • @gregoriikatastrov7472

    @gregoriikatastrov7472

    5 жыл бұрын

    Can you imagine the people that will make their lives more difficult because of no reason? After all they would have to nurse that deaf baby for at least 18 years. Thats kinda dumb idea. And surely there will be some kind of regulations on this process.

  • @finderskeepers8

    @finderskeepers8

    4 жыл бұрын

    Exactly. D/deaf or HoH people are part of a culture. Removing deafness or blindness would be removing the culture. It is a struggle in society mostly due to inaccessibility.

  • @DGP406
    @DGP4067 жыл бұрын

    what kind of parent wouldn't want his\her baby to be safe from cancer or diabetes?

  • @Gerpar_

    @Gerpar_

    7 жыл бұрын

    Anti-Vaxers

  • @orhalperin892
    @orhalperin8927 жыл бұрын

    awesome video Joe!!!

  • @saandyyvh6682
    @saandyyvh66826 жыл бұрын

    This is very interesting! Customizable children. It would be interesting to think about what genes could lead the gene popularity contest, how it would change our diversity, and perhaps even body type. Like in a totally sci-fi setting, what if it's socially looked down upon if your child is NOT like the rest?

  • @RandomUploader7
    @RandomUploader77 жыл бұрын

    We will create soldiers. I guarantee it.

  • @taranciucgabrielradu
    @taranciucgabrielradu7 жыл бұрын

    Welp, with great power comes great responsibility

  • @cyantulip
    @cyantulip5 жыл бұрын

    3:55 Every time Joe says “another”, I get a flashback of “another one...and another one...and a-NUH-ther one!” 😄

  • @natesh1
    @natesh17 жыл бұрын

    Thanks for video, its really amazing!

  • @imcintyre01
    @imcintyre017 жыл бұрын

    I'm sick to my stomach now.

  • @Ibnblackbird
    @Ibnblackbird7 жыл бұрын

    last time I was this early Iris was still alive on flash

  • @Ibnblackbird

    @Ibnblackbird

    7 жыл бұрын

    White Gangster Panda I'm so sorry brother. I'm so sorry

  • @feynstein1004

    @feynstein1004

    7 жыл бұрын

    Lmao mate. Don't worry. She's in the last episode.

  • @alecwinner
    @alecwinner7 жыл бұрын

    I'd sign up for this in a second, cure my genetic mutation and like half the problems in my life, from constant pain, to inability to walk properly would be cured instantly. Sign me up

  • @XTeaOrCrumpetsX
    @XTeaOrCrumpetsX7 жыл бұрын

    I'd recommend reading "Brave New World" if you want more information on the ethics. I think it is important that we have differences in human characteristics and traits.

  • @thelethalmoo
    @thelethalmoo7 жыл бұрын

    how long until we can design our own genes and be able to predetermine exactly how to change what for what effect... I say worry about the ethics later, it's gonna happen eventually. peoples idea of what is wrong and right seem to change based on what science is like at the time... I want glow in the dark ears and no one can stop me

  • @melvinpariyadan4884
    @melvinpariyadan48847 жыл бұрын

    Is it ever possible to change the genetic information, so that we can stop random mutation? I think random mutation always uses a minimalist approach, so if we evolve too efficiently by changing genetics ourselves, random mutations might try to bring us backk to the more minimalist style or the clash between our changings and random mutations would cause unwanted results.....p.s this video is the only thing i know about CRISPR so nothing what am saying might be facts.

  • @MisterDewong

    @MisterDewong

    7 жыл бұрын

    Melvin Pariyadan Cool idea. I don't know if CRISPR would be used to do this though. I think this would be more of a genetic "protective barrier" of some sort. Genetic mutations occur randomly when our cells replicate DNA in order to divide which would be the biggest problem in the way. As far as we know, our genes don't want to randomly mutate. Although, would we want to stop this from happening? After all, we are human due to random mutations and natural selection.

  • @melvinpariyadan4884

    @melvinpariyadan4884

    7 жыл бұрын

    Mel hooprah thanks for the good reply. You're right! I now just realised how important random mutation is. OMG i don't want it to go away now, that would bury is too deep in a dystopia

  • @georgegray2712
    @georgegray27127 жыл бұрын

    Great video thanks mate!

  • @roslynnflores3276
    @roslynnflores32765 жыл бұрын

    I think we should do this! Make ppl better eventually from the get go! Either way things happen, thanks for the informative video!

  • @krishnarao4290
    @krishnarao42907 жыл бұрын

    being an Asian, I like the video at 0:07, I dreamt of that all my life!! 😢😢😢

  • @panpiper
    @panpiper7 жыл бұрын

    We must. Ultimately we will have no choice but to do the designer baby thing. We have long stopped selecting for survival. For a long time now, people who in the past would have not survived to pass on their genes are now surviving and having children. Those children in turn go on to have more children with others who are similarly less survivable without the benefit of modern medicine and convenience. The literal fact is that the human genome, on the whole, is degrading, and it is degrading fast. Designer babies is in essence the solution. As a for instance... Do we do a prospective child any favors by allowing them to be born with substandard IQ? The answer is to me an utterly unambiguous no. Where is the harm in having more intelligent people? We have an ethical responsibility to give our children the best possible future, and that includes the best possible genes.

  • @theunknownperson5632

    @theunknownperson5632

    7 жыл бұрын

    I know this is unrelated but I never thought of intelligence as a gene controlled thing

  • @ungureanubogdan2398

    @ungureanubogdan2398

    7 жыл бұрын

    Theunknown Person think it's more of a predilection to certain factors

  • @axue4248

    @axue4248

    7 жыл бұрын

    I'm pretty sure that there is a genetic correlation between genetics and IQ even when factoring for environment. I mean think of it this way, if you inherit everything from your parents including your height, hair colour, race etc, why wouldn't you inherit your parent's brain?

  • @theunknownperson5632

    @theunknownperson5632

    7 жыл бұрын

    Axue it makes total sense to treat such genetic diseases but to make everyone have the same genes has some implications. Honestly i think we should fix genetic problems and improve our genes but not use it for fashion purposes

  • @Killinemkid

    @Killinemkid

    7 жыл бұрын

    Theunknown Person Not everyone would have the same genes. I would want my kid to have medium brown skin, olive eyes, and white hair-making it easier to dye, along with the gene to increase speed, the ability to sing, and anti-aging hormones. Some people will want their kids to be very pale, with red hair, and blue eyes, extra muscle mass and a stronger immune system. Genetic diversity would increase, not decrease.

  • @saishkhanna
    @saishkhanna3 жыл бұрын

    Do more of this series

  • @WarisAmirMohammad
    @WarisAmirMohammad7 жыл бұрын

    love the Monster Factory intro