In case anyone is curious, her beautiful Irish name is pronounced “ee-fa”. 🥰

@whirledpeas3477

2 жыл бұрын

Cool 😎

@kingalf4828

2 жыл бұрын

I was literally just gonna look that up.. cheers

@Duckfest

2 жыл бұрын

Thanks. I don't recall ever seeing a name as Irish as hers. I love it. I also think Professor Aoife McLysaght would be an excellent name for a character in a fantasy novel.

@dboots123

2 жыл бұрын

Her name is the first reason I clicked for this video. Thanks for the info 🙏🏼

@jerfacekilla

2 жыл бұрын

THANK YOU! Literally spent most of the video trying to figure out her first name and watching ...😅

Truly an excellent presentation!!! Thank you so much for putting these online: its a great service and helps the general public understand complex matters by giving a lot of background material without anything overly technical.

@mohammedalhuneini219

2 жыл бұрын

Excellent presentation After minute 25:00 there is error in the Hb curve The fetal Hb (HbF) she is talking about is actually made of alpha/gamma not alpha/delta Otherwise a very wonderful talk

awesome on so many levels, no wonder she was exhausted in the end! i wish she'd make a whole lecture series of this with much more detail...

@ambrosewanjala8843

2 жыл бұрын

Seconded. Truly awesome

My daughter is homeschooled and will be watching this, there aren’t enough women in science and this simple explanation of a complex subject is something we need far more of, thank you. Great video.

@eddie1975utube

2 жыл бұрын

So nice to read your comment. Where I live in Alabama, 99% of home schooling parents would never show their kid such a video.

Aoife McLysaght I really enjoyed this lecture. Your view on life is extraordinary!

Charming with a purpose. Salute to The speaker and RI.

The Irish delightfully comes out more and more as she carries on speaking.

@martinpollard8846

4 жыл бұрын

I "tink" you're right

Thanks for this breathless presentation by a confident and erudite young person. I've learned a lot here, by being captivated throughout.

@AceofDlamonds

3 жыл бұрын

"young"? She's a professor

@thomasbriggs4718

2 жыл бұрын

Young compared to me…

Introduction 00:00 I will talk about evolutionary genetics 00:00 how evolution relates to the field of biology 03:50 What is a gene ? 07:43 DNA, duplicating genes 11:25 Evolution by gene duplication Examples of gene duplication 13:55 Human sense of smell 16:45 Evolution of colour vision 20:20 Globins What can we understand 26:40 Patterns of evolution 31:50 Why is there so much diversity (vertebrates/humans) 36:20 When gene duplication is problematic (pathology) 43:30 What to look for in DNA 48:15 Dosage sensitive genes

@spook_dad

5 жыл бұрын

please link to the smell your bum quote

@allwinaugustine

4 жыл бұрын

Good job elias!

@chipparker3950

4 жыл бұрын

A patently improvable statement. Amazing arrogance.

@jamesdolan4042

3 жыл бұрын

@@chipparker3950 I did not hear say anything about improvable adaptations just for the sake of it. She spoke of how olfactory genes in DNA duplicted and simultaneously changed ever so slightly to optimise survival for the species at that juncture in time. And conversely how these genes become redundant when optimizing survival does not need them. There was nothing arrogant about her iinformed and learned opinion. If you think differently I would appreciate you explaining it.

how to take an audience from the most basic explanation of DNA structure to cutting edge genomic science. Brava!

Thank you - Royal Institution- A detailed science talk without Equations ! Cheers !

Excellent presentation, very insightful. Thank you Dr. McLysaght, and thanks to the Ri.

Truly brilliant! Thank you Dr. McLysaght and the RI for putting this online. Its really as lucid as it can be, and so vital to making the general public understand where we're at, in terms of advancement in this area and the possiblities. I've shared this lecture with many. Look forward to seeing more from Dr. McLysaght..

@mattnewman5673

Жыл бұрын

Very informative . Thanks a lot Dr. McLysaght. I am not color blind about Genetics any longer.

Best speaking / teaching voice I have ever heard - concise with perfect clarity and not a moment spent on searching for words. You can tell she put a tremendous amount of thought into every idea she conveys to help us come to a basic understanding of a very complex science. I'll have to watch this several times. There is so much valuable information here.

@Insoo223

2 жыл бұрын

Totally agree!

“Some Assembly Required” by Dr. Neil Shubin has a chapter on Gene duplication. I’m halfway through the book. Watching this lecture really helped further cement what I read. I highly recommend Dr. Shubin’s three books, in this order: Your inner Fish The Universe Within Some Assembly Required.

What a Brilliant talk. So informative, simple and elegant. Congrats !!

Excellent! Copy number variation explained and explained beautifully!

One of the very best RI presentations. Love her accent - just slightly Irish and only ever really announces itself when she says 'tink' - fabulous.

@talideon

3 жыл бұрын

She sounds like a typical middle-class Dubliner. She _is_ contrasting _t_ and _th_ though: the _t_ is an alveolar stop while the _th_ is a dental stop.

I am sending the link for this video to my granddaughters. Professor McLysaght is inspiring.

yes, exceptional presentation, so look forward to hearing more from Ms McLysaght in the future

You've given us more than just a sense. Thank you for an excellent talk! :-)

Thank you, Aoife, for acknowledging Susumu Ohno. He is one of my heros!

Even after so many years, still an incredibly informative lecture!

This is one amazing, professional well produced video, I hope she has the time, energy and resources to creates many more videos like this which I really appreciate..!

what a lovely, smart and charismatic...lecture

Good presentation. Thank you for sharing! :)

Hi Aoife, a beautiful and captivating lecture, of a highly complex subject, made so watchable by your excellent delivery and style.

Simplicity and beauty is evolutionary. The presence of this curious beauty is wonderful. Thank you

Excellent presentation. Congratulations !

Really enjoyed the performance, thankyou for sharing your knowledge and skill it was great to learn so much about standing up and delivering a complicated topic. Thankyou so much.

Outstanding lecture and brilliant summary of information with great use of comparisons and analogy! Thanks for sharing!!!

This is an excellent lecture, well presented and clear. Thanks, Dr. McLysaght! Thanks, Royal Institution!

She is such a wonderful, engaging, and knowledgeable presenter of some complicated steps in the expansive, total effect of (short "e" ... I'm American) evolution on the science of life. Extraordinary!

@heinpereboom5521

2 жыл бұрын

A beautiful woman and wise words are not the same.

her name. what a kickass name. sounds like it's destined for greatness. i bet when she tried to make an account and typed just her first name, google was like... yeah that's available.

What a truly brilliant lecture.

" too much of a good thing" was fab found it really informative ! Thanks

This talk showed me something which was hiding in the plain sight right in front of my nose. Awesome presentation. Fascinating research.

Excellent subject and content!

So well presented! Great talk!!

Exceptional seamless progression of knowledge. Other presenters should try to emulate this. Best of luck.

Alright, I've finished watching and I've come to the conclusion and I'm in love with the form of this presentation. This is great work. I'd love to learn more in-depth things about the genome now

@LairdJ56

6 жыл бұрын

have you learned more about the genome now? there are loads of amazing free resources to learn from... That is the reason God invented the internet.

@williamgoode9114

3 жыл бұрын

Yes Adam, plus the individual smart phones, and the instructions to care about ; climate,flora and fauna, via fires,floods & virus.

@MacNif

Жыл бұрын

God = Internet ...whoa?

Interesting. I´m learning biology for the first time and this ignited more interest for the subject.

Beautifully explained and very engaging talk.

This lecture is one of the most incredible I have seen. I have a personal interest in evolutionary biology and I studied bio in college. Remarkable insight with this research

This was a great talk. I never knew about the 4X event in human evolution. Thank you Dr. M!

As always very interesting!

Some people really have a gift for presenting. She is incredible. There is some interesting cross pollination of ideas that adds something to what is more traditional material I have seen on the subject.

I have been obsessed with science since I was a little boy I do not have many friends because nobody likes science in my family and my friends think that I am showing off and I try to tell them I have no degrees I’m very humble I don’t consider myself smart but I can learn and I have been learning for a long time and she’s just another step on my letter of science I appreciate all her knowledge I have learned something today I just hope I remember I’m getting older sorry letter should be Latter

@schmetterling4477

Жыл бұрын

You need to get help, too. ;-)

17:44 "Rhodopsin" doesn't derive from "rod" -opsin, but from the Greek word for pink ("rhodon"), because of its colour. (Just for info, and not a criticism.)

@coolworx

2 жыл бұрын

Rhododendron!

I love these presentations ;p

I love the interest in this wonderful informative magical lecture. Simple yet complex enough to follow. I simply find the info so fascinating because the intricacies of life are so wonderful. The UNI-verse with all of It's elements are nobless than magical.

Thank you! I heard every word, and understood everything.

Take a breath.. you nailed it! 👌🏽

You really don't need to waste time debunking creationism. The people that back it aren't listening anyway.

This is packed with valuable insights!

Great presentation, so well articulated with examples specially the aircrafts with places where bullet hits were not found.

@jasonwiley798

Жыл бұрын

This also known as the mortality bias , a common statistical phenomenon.

Excellent! I wish I had seen this lecture years ago. Very informative, and a very good style of presentation. Let's see if there's more from Aoife McLysaght.

I love your presentation ! It's amazing !

How educational! Thank you, Professor!

Fascinating talk. Just awesome.

Not being an expert in the field of biology, this lecture was a real eye opener!

@heinpereboom5521

2 жыл бұрын

Maybe that's why?

This is something I needed to know. I have this idea to make special neural networks that evolve.(Not a new idea but mine is an improvement). I was wondering how genomes get longer over time and I'm pretty sure I found the answer in gene duplication. I also think it solves other problems I predicted, I can't remember. I just had it on the tip of my brain but I lost it.

Beautifully explained

Happy to be evolved enough to understand this great presentation.

I am a biology teacher. This was truly enjoyable!

@heinpereboom5521

2 жыл бұрын

So what did she really say about the beginning of life? I only heard what happened after that beginning.

@jamesdolan4042

2 жыл бұрын

@@heinpereboom5521 She said that the simple DNA molecule is already present in the fertilized egg, and that the DNA does not change throughout the life of the organism. Her presentation is not about the biology of reproduction or the origon of life that occurred eons ago.

@heinpereboom5521

2 жыл бұрын

@@jamesdolan4042 In this way all evolutionists speak, they never talk about the beginning, because they can never explain that, because it is fantasy and belief. Her whole presentation suggests that evolution is correct and that is very unbelievable to me if you always skip the beginning of it. That's what I meant.

@jamesdolan4042

2 жыл бұрын

@@heinpereboom5521 Since you put it that way can you provide me with undeniable, verifiable, singular, proof how life as we know began?

@heinpereboom5521

2 жыл бұрын

@@jamesdolan4042Of course not, so nobody can, I thought you understood that. So if you believe in a creator, that is a belief and that also proves nothing. At least believers say they have a belief and evolutionists say they have a science and that is just nonsense, they too have a belief in their own idea no more than that. So very unscientific. When scientists deal with this sort of thing, it's pseudo science. Moreover, science may not exclude anything, that is a prejudice, so not scientific. Even a scientist cannot rule out the possibility that there is a creator, even if this can never be proven.

Extraordinary. This shows how useful Evolution as a theory really is!

Fascinating, great presentation.the lady’s accent makes you take notice

At 30:54, it is interesting to compare the structure of hemoglobin and chlorophyll C1 and C2. Very similar, hemoglobin has an iron molecule in the center and chlorophyll has a magnesium molecule. Mother Nature found a useful carrier complex in plants and tweaked it in animals. She doesn't fix it if it ain't broke, just a little tweak. FYI, chlorophyll a, b, d and f have long side chains but the central complex is almost the same in all types. Another example, compare auxin and melatonin, auxin in plants and melatonin in animals.

This is great. Thank you Aoife McLysaght.

@aoifemclysaght3586

10 жыл бұрын

Thank you :-)

@RalphDratman

10 жыл бұрын

Aoife McLysaght You explain things clearly, you look good and you sound great. I would like to watch any other lectures you might have online. If you don't have any other videos online yet, perhaps you would consider making some? You don't need anything more than an iPhone, iPad or Android device to accomplish that. Having a helper to hold the camera makes things easier, but that is optional. You can do an entire video by yourself.

@tantiwahopak101

5 жыл бұрын

@The Truth of the Matter yes. She is real. Check it out.

@tantiwahopak101

5 жыл бұрын

@The Truth of the Matter wow so this is ur reason for her to not being real? Not all people are famous u know that right?

@EricDittmarrice

5 жыл бұрын

@@aoifemclysaght3586 Thank you. Stay gold!

What a powerful, pleasant, presentation: Aoife has the presence of an actress, one who could easily carry a starring role in a movie or television series! - j q t -

Brilliant presentation. I learned a lot.

Aoife is my new focus. 23:00, reminds me of a color experiment with non and savannah living heritage. Savannah heritage make reference in mind and name varying differences in the color pigments in their environment. Non environment make reference to a prescribed knowledge of the color wheel so to speak. Each tested on juxtaposed color charts had trouble distinguishing slight variances in the colors that they were not used to.

What a lovely woman! ....her person, her insight, and the way she shares it with others.

I love super smart women

Thank you! A beautiful presentation.

The Beauty of explanation 😍

Excellent, even I understand it and I've been accused if missing a chunk of my DNA. When she pronounces "think" does she actually say "tink?" Must be in the Irish DNA.

Very informative. What do you think of Dawkins's definition of a gene, where it is defined as the smallest section of a chromosome that can potentially last over deep time? The definition you give, which is a gene is a section of a chromosome that codes for a certain chain of amino acids, is what is taught in school. However in 'the selfish gene', Dawkins tells us something different. Is there a 'conventional' definition, or is the issue still subject to debate?

Incredible knowledge and takes evolution to another level.

Beautiful, lyric. I can listen to her pronunciation all night..

Instantly in the running for "Best RI Lecture". Who could resist learning genetics from a beautiful elf straight out of Tolkien?

@mokobaby6181

3 жыл бұрын

27:25 she gets a little flustered at her drawing of a plane.

what a nice dress and great presentation lol

Brilliant expose, thank you

A remarkable show of fluency across such a wide array of disciplines making up the study of biology. Informative, impressive, and inspiring. Just a thundering and authoritative barrage against any possible anti-evolution understanding of how life works.

I love ice cream and cheeseburgers so I am quite happy to carry the mutation that let's me stay lactose tolerant all my life. But I don't like fruit and veg, so I want my Ligo gene back! Heh. This presentation is just as engaging as any by the cosmologists or physicists.

In programming language: a gene is a variable length field within the DNA database.

Absolutely brilliant! :)

I loved this lecture

No supernatural deity was needed in this presentation about life.

@brucemulvey9948

5 жыл бұрын

Marco Meerman That’s right. That’s the point after all isn’t it?

@williamgoode9114

3 жыл бұрын

No, but science will, via AI+Net, encouraging better behavior for a varied and sustainable PLANET.

16:00 "we no longer sniff each other's bum" nice one 😂

@epajarjestys9981

4 жыл бұрын

I do.

Learned great information- thanks 🙏

Outstanding and informative presentation

"this is where the magic begins" - she said this in that dress and I simply could not NOT think about Tinker Bell :- )

I am terrible at speaking in front of a group and would not wish to criticise but if she slowed it down a bit she would be magic.

@RalphDratman

10 жыл бұрын

She has a lot to communicate in a relatively short time.

@RalphDratman

10 жыл бұрын

FRANCIS FALUDI I agree! In fact, I sent her a message suggesting she make more youtube videos!

@bickleigh3283

10 жыл бұрын

For a lecturer I though her pacing was spot on!

@RalphDratman

10 жыл бұрын

Bick Leigh It was for me, too, but I think people really differ in the rate they prefer. I like to hear a lot in a short period of time -- as long as I can follow what's being said. Others might want more time to digest what's been said.

@timlandscheidt

9 жыл бұрын

FRANCIS FALUDI I'm pretty sure I heard a sigh at the end of the video :-).

Well done dear lady. Bravo!! 👏

Going to have to watch this again to understand better.

Invoking ID or Creationism comes easier to theists than learning new concepts as an adult because they've been exposed to these cultural, subjective ideas from birth. It's easy to speak the language you've grown up with... it's just who you are. Attempting to speak another language takes up to a year of learning. The same goes for religion. Their brains are structured for religiosity due to a congenital/pedagological indoctrination. It's not their fault but you can't force these people to suddenly change their neurology which was established over decades. They have to want to learn and change themselves but that will only happen if they're intelligent enough. Unfortunately, religiosity is negatively correlated with education/intelligence.

@unitelanka

7 жыл бұрын

organized religion is no different from cults. we've heard about how difficult it is to 'deprogram' people that have been taken in by cults.

@mozkitolife5437

7 жыл бұрын

+JZoidberg Agreed. IMO the only difference between organised religion and a cult is the number of people subscribing to them.

@colinscholey

6 жыл бұрын

that is a very narrow minded viewpoint try studying all the religions including the alien annunaki therory and try linda moulton howe if you dare ...she will blow your tinhat right off...the idea that nothing has produced dna is laughable...as is the idea that there is not an alien overlord...look at the face and pyramids on mars...

@bobaldo2339

5 жыл бұрын

Yes and no, Jason. What you think of as "religiosity" is conditioned by your own upbringing, in other words by your own culture. Westerners tend to see all other religions through the distorted lens of the 3 desert religions.

@paulinecoburn181

4 жыл бұрын

Jason Axford Religiosity?

Kate Mckinnon is a geneticist now?

Einfach - Klasse (Simply the Best). the young lady should be teaching this to GAMSAT students

Amazing lecture, thank YOU!