Claisen Condensation Reaction Mechanism

This organic chemistry video tutorial provides a basic introduction into the claisen condensation reaction mechanism which involves the reaction of two esters and an alkoxide to produce a beta keto ester. This video contains plenty of examples and practice problems.
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  • @TheOrganicChemistryTutor
    @TheOrganicChemistryTutor5 ай бұрын

    Final Exams and Video Playlists: www.video-tutor.net/ Full-Length Math & Science Videos: www.patreon.com/mathsciencetutor/collections

  • @zsmith550
    @zsmith5502 жыл бұрын

    this man has been carrying me through my major in college

  • @PunmasterSTP

    @PunmasterSTP

    Жыл бұрын

    What's your major?

  • @alejandrosantos1879
    @alejandrosantos1879 Жыл бұрын

    This guy does better explanation than ph.d profesors, better examples than the online homework!

  • @TheSepticSid
    @TheSepticSid2 жыл бұрын

    Thanks man. Been watching your vids for years now so again thank you.

  • @26d8
    @26d83 жыл бұрын

    Great explanation Sir, Would it be possible for you to make more videos on alkylation, acylation, adol reactions, beta elimination and related rxns, heterocyclic synthesis and reactivity Pleaseee They way you explain is very clear.

  • @PunmasterSTP
    @PunmasterSTP Жыл бұрын

    This might be basic of me to say, but thanks again for all these great videos!

  • @nourkourbeh7152
    @nourkourbeh71523 жыл бұрын

    Thank you for all your videos

  • @sandeepsinghbisht3489
    @sandeepsinghbisht34892 жыл бұрын

    Thanks for extras🙏🙏....it helped to understand better

  • @sierrabarlow4109
    @sierrabarlow41095 жыл бұрын

    Bless you

  • @PunmasterSTP

    @PunmasterSTP

    Жыл бұрын

    How'd it go!?

  • @jonathansanchez8802
    @jonathansanchez88023 жыл бұрын

    bless you, gotten ,me through both Ochems!

  • @tarunkumar.m8887
    @tarunkumar.m8887 Жыл бұрын

    great explanation sir!!!

  • @kalyanikudalkar5037
    @kalyanikudalkar50373 жыл бұрын

    Hello, can you please explain perkin condensation too?

  • @jesusmrosario-claudio4104
    @jesusmrosario-claudio41043 жыл бұрын

    Thank you once again.

  • @revathin7292
    @revathin72922 жыл бұрын

    Will the Ester part hydrolyse into alcohol if we have 2eq of hcl?

  • @kayth1373
    @kayth13732 жыл бұрын

    this is a lifesaver

  • @kaviyarasanm7133
    @kaviyarasanm7133 Жыл бұрын

    Sir Why ethoxide ion not attack Alpha corbon in in the first reaction?

  • @malkaleban4330
    @malkaleban43302 жыл бұрын

    Thanks!

  • @silverdove9911
    @silverdove99115 ай бұрын

    this man knows everything under the sun

  • @electro8032
    @electro8032 Жыл бұрын

    Can you make a video on perkin's Condensation,Please.

  • @tamannaparveen735
    @tamannaparveen7356 жыл бұрын

    Thanks upload daily for neet ug 2019

  • @songohan393
    @songohan3932 жыл бұрын

    thanks

  • @user-pg3hw9qg8t
    @user-pg3hw9qg8t Жыл бұрын

    Awesome

  • @rahullovesthepayne8690
    @rahullovesthepayne86902 жыл бұрын

    why does it attack the alpha-hydrogen only? And also, why ethoxide is a good leaving group?

  • @sandeepsinghbisht3489

    @sandeepsinghbisht3489

    2 жыл бұрын

    EtO- is weak base and also there is no other better leaving group than EtO-

  • @fiaahuja
    @fiaahuja Жыл бұрын

    Why does it needs to match?

  • @wissen5410
    @wissen54106 жыл бұрын

    Interesting

  • @saiei
    @saiei3 жыл бұрын

    Nice

  • @jyji6976
    @jyji69764 жыл бұрын

    why hydroxide can attack carbon directly but not when it was Eto? (Eto attacked alpha hydrogen first)

  • @bailassandijani3788

    @bailassandijani3788

    3 жыл бұрын

    Because Eto is not sterically hindrance so it will not added to carbonyl group at first

  • @mahfuzamarzan3905

    @mahfuzamarzan3905

    2 жыл бұрын

    Thanks

  • @bailassandijani3788
    @bailassandijani37883 жыл бұрын

    why the LDA didn't react directly with carbonyl carbon at first but it react first with alpha hydrogen?

  • @anjaleitner9171

    @anjaleitner9171

    3 жыл бұрын

    LDA isn't nucleophilic

  • @sandeepsinghbisht3489

    @sandeepsinghbisht3489

    2 жыл бұрын

    Because Acid -base rxn happens at a very faster rate. Then Nu attack

  • @JoeyVX
    @JoeyVX3 жыл бұрын

    Can HCL be substituted with sulfuric acid?

  • @JoeyVX

    @JoeyVX

    3 жыл бұрын

    @@asmaakram250 yes thank you, I was able to understand perfectly, a stronger acid can replace a weaker acid only in this reaction they are using HCl and I wanted to know if sulfuric acid a weaker acid can be used instead of HCl not the other way around. So for instance I would be using sulfuric acid to form the ketone. I think it can be used instead only it would require a larger quantity of sulfuric acid over HCl I presume

  • @ivantimofeev2233

    @ivantimofeev2233

    3 жыл бұрын

    yes, and it actually would be better a stronger acid gives a better kinetic constant but be careful with the concentration of the sulfuric, in my experience, going over 70% chars the reagents (basically reduces all organic compounds to elemental carbon, which is not great)

  • @JoeyVX

    @JoeyVX

    3 жыл бұрын

    @@ivantimofeev2233 I appreciate your comment, thank you for your input. The good thing is that the reaction takes place in an aqueous soln. and the sulfuric acid would be added slowly but I guess it would be best to pre-dilute the sulfuric acid before addition. I actually ended up trying sulfuric acid and it worked, it was performed at mg scale just as proof of concept and it worked great. Took quite a lot of sulfuric acid, I was surprised.

  • @bluer_3392
    @bluer_33924 жыл бұрын

    bless you

  • @GBK100
    @GBK10011 ай бұрын

    🎉

  • @saiei
    @saiei3 жыл бұрын

    Bless u Lol