Chronic Lymphocytic Leukemia (CLL)

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Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Chronic Lymphocytic Leukemia (CLL). CLL is a type of cancer that affects the blood and the bone marrow. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Chronic Lymphocytic Leukemia (CLL) Introduction
0:55 Hematopoiesis Pathway
5:36 Pathophysiology
17:49 Diagnostic Approach to CLL
26:27 Treatment
33:49 Comment, Like, SUBSCRIBE!
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Пікірлер: 207

  • @jefflyons6433
    @jefflyons64334 ай бұрын

    If I had teachers like you, I might have gone to med school. I recently learned that my wife has CLL. Even though I'm not in the medical field, I want to learn everything I can about her condition and your talks are absolutely amazing! One of the worst things of a disease is the unknown, and you have done so much to help me understand her situation. Thank you, thank you, thank you.

  • @asgio27

    @asgio27

    2 ай бұрын

    Yes, very good instructor. Just got my diagnosis yesterday. Will be looking for lots of information. Good luck go wife.

  • @connorcosgrove2240
    @connorcosgrove2240 Жыл бұрын

    That’s what my mom has, she got diagnosed with it on April 1, 2015. She waited treatment wise until January of 2021. She ended up doing immunotherapy for 5 months back in April of 2021. After her last treatment, she now has follow ups monthly to as of right now once every three months. She takes ibrutinib everyday along with acyclovir twice a day for shingles and celebrex for arthritis in her knees

  • @greedysourceofgod4819

    @greedysourceofgod4819

    9 ай бұрын

    How old is your mom , since my dad got diagnosed these past week

  • @connorcosgrove2240

    @connorcosgrove2240

    9 ай бұрын

    @@greedysourceofgod4819 young, mid 50s

  • @sonyafox3271

    @sonyafox3271

    9 ай бұрын

    You aren’t made to wait for treatment, a lot of times at the time your diagnosed there maybe no need for any kind of treatment right away unless something is going on where the cancer isn’t active per say and, that’s why your mom didn’t do or receive treatment till 2021! Example, I was diagnosed with CLL at the age of 42, however, I didn’t need treatment till 3 yrs later and, it wasn’t for the fact, I had to wait a certain period before, I got treated, the cancer was not active or rather nothing was going on till then, that required a reason to get any treatment!

  • @user-je1ly1th2w

    @user-je1ly1th2w

    4 ай бұрын

    She must be one strong woman. My husband was put on Ibrutinib and it put him in the hospital for nine days. They had to change to Calquence, and he did better on that.

  • @olydnk5270

    @olydnk5270

    2 ай бұрын

    ​@@sonyafox3271that's what she meant. She waited for treatment because the stage of the cancer wasn't yet at the point of treatment. It is not about being active..but stages of development as clearly explained in the video. Stage 0 you do nothing. Just wait... Etc etc

  • @user-je1ly1th2w
    @user-je1ly1th2w6 ай бұрын

    The love of my life got CLL as the result of exposure to Agent Orange when he was serving on two different Navy aircraft carriers during the Vietnam War. We lost him in February of 2023, after cancer took his bladder and prostate (not uncommon for CLL patients), as well as multiple skin cancers - all going on in his body at the same time. If you or someone you love has CLL, don’t postpone treatment. And God bless you.

  • @shooterps2434
    @shooterps2434 Жыл бұрын

    you already helped me in physiology and now a few years later in clinical oncology. you're the best

  • @user-bi4bi1ip3m
    @user-bi4bi1ip3m6 ай бұрын

    Have had CLL but never had it really explained to me. Now I have a much greater understanding. Thank you.

  • @ahmedgibrel1162
    @ahmedgibrel116211 ай бұрын

    Tons of thanks for such an outstanding tutorial

  • @ClassicB3bituh
    @ClassicB3bituh9 ай бұрын

    You are so amazing!! I cannot stop bragging about your lectures to all my med student friends. ❤

  • @user-eg6ui2qz5e
    @user-eg6ui2qz5e Жыл бұрын

    Thanks for your supporting❤❤❤❤

  • @livm99
    @livm99 Жыл бұрын

    i'm a biomed. student and these videos really help me understand hematology better

  • @tinkerfae1977
    @tinkerfae1977 Жыл бұрын

    ❤brilliantly presented lecture, so helpful and easy to follow, thank you guys x❤

  • @snowbunny8189
    @snowbunny81899 ай бұрын

    Love this! I'm learning so much.

  • @salam7905
    @salam790510 ай бұрын

    thank you so much really appreciate all the work you put into these lectures 💐💐💐

  • @user-hx7xz9rt8k
    @user-hx7xz9rt8k Жыл бұрын

    Yay 🎉🎉 I’ve been waiting for CLL thank you ❤

  • @abdulazizhalimov
    @abdulazizhalimov3 ай бұрын

    I appreciate all the efforts you have done for these incredible whiteboards..

  • @ethelski1
    @ethelski1 Жыл бұрын

    Great info, great teacher🙌

  • @fatimasyed9156
    @fatimasyed91564 ай бұрын

    Amazing content.Basics explained very nicely.

  • @zafarqarizada8173
    @zafarqarizada8173 Жыл бұрын

    Wow keep uploading thanks 😊

  • @hone7719
    @hone77195 ай бұрын

    u said "please" so sincerely that i liked the video before watching eyes teared

  • @maureenmonney60
    @maureenmonney609 ай бұрын

    Thank you! Love your videos.

  • @noone00000
    @noone00000 Жыл бұрын

    Just been diagnosed with CLL so I'm just trying to understand it thank you

  • @faithfisk2199
    @faithfisk21992 ай бұрын

    These are great lectures; so helpful

  • @brendaliz1989
    @brendaliz1989 Жыл бұрын

    Thank you for this most informative video!!!

  • @nataliiaivanova6943
    @nataliiaivanova6943 Жыл бұрын

    Thank you, so proud of you 👏 🙌

  • @user-wn6lz3ff9u
    @user-wn6lz3ff9u7 ай бұрын

    Amazing explanation, I really appreciated your countless effort to bring this high quality education for free.

  • @olydnk5270
    @olydnk52702 ай бұрын

    Brilliant well presented thank you.

  • @user-gx5pf7tp9i
    @user-gx5pf7tp9i9 ай бұрын

    You are the best doctor worldwide

  • @user-wo9dq1gu8o
    @user-wo9dq1gu8o Жыл бұрын

    Every word will not be enough to thanks you right Thanks for every thing that you do here Your effort will not ever fogetten ❤

  • @user-zv1dm2gy7p
    @user-zv1dm2gy7p16 күн бұрын

    Thank you a lottt! What a great channel.

  • @hudashah2255
    @hudashah225510 ай бұрын

    thank you for the video!!

  • @user-ok3cq3fg1e
    @user-ok3cq3fg1e9 ай бұрын

    Wonderful incredible outstanding idea of coming up with such KZread channel. Millions and probably more than that support your channel and they say between them that it’s helpful even though they don’t comment here. Keep up with this job. Your channel is no. 1 ranked in my opinion.

  • @AhmedAdel-hx9ce
    @AhmedAdel-hx9ce3 ай бұрын

    Thank you for your hard work ❤❤

  • @johnlokpar6434
    @johnlokpar643411 ай бұрын

    Good job Prof Zach

  • @funnytube6570
    @funnytube6570 Жыл бұрын

    Thank You🙌🏽

  • @Ilovesunrise25
    @Ilovesunrise259 ай бұрын

    amazing video as always

  • @naturesoundshome9864
    @naturesoundshome9864 Жыл бұрын

    Thank you 😊

  • @rachellehales9442
    @rachellehales94427 ай бұрын

    love how well you explain these complex concepts! this lecture really helped me with my research paper. keep being amazing! how do you know so much about so much?

  • @narjesalbazi7190
    @narjesalbazi7190Ай бұрын

    Thank you so much 😊

  • @araphamvugalo6521
    @araphamvugalo65216 ай бұрын

    Perfection as always

  • @roeeamir7020
    @roeeamir7020 Жыл бұрын

    Thank you for the video

  • @kaytee789
    @kaytee789 Жыл бұрын

    Thank you so much 🙏❤

  • @user-oc9pf5de7z
    @user-oc9pf5de7z Жыл бұрын

    our great teacher thank you

  • @Roger-hu4tk
    @Roger-hu4tk Жыл бұрын

    Thank you so much

  • @KR-jz9xv
    @KR-jz9xv10 ай бұрын

    Amazing! Tyssm Zach

  • @walaaalbokhaity3390
    @walaaalbokhaity3390 Жыл бұрын

    Thank you very very much

  • @rawanalmansouri
    @rawanalmansouri Жыл бұрын

    Thank you❤️

  • @udaykiran8061
    @udaykiran806110 ай бұрын

    Thank you very much ❤

  • @SukhwinderKaur-us6em
    @SukhwinderKaur-us6em6 ай бұрын

    Sir u are really a diamond of the medical science ...loves u a lot ....keep supporting us sir we need ur help❤❤❤

  • @lilysal8858
    @lilysal8858 Жыл бұрын

    I really dunno how to thank you, ur such an angel God sent to us , thank u so much for posting ur videos and these amazing info for free, ur amazing bro , love ya ❤!

  • @ab97md
    @ab97md Жыл бұрын

    thank you zach

  • @elizabethchryst3297
    @elizabethchryst32974 ай бұрын

    I was just diagnosed with CLL. (Feb. 2024) I am not symptomatic yet and will be living near MD Anderson in Texas. Should I consider a clinical trial for CLL? I am relatively young (not yet 65 yrs old) Thank you for all you do! God Bless!

  • @luckyfat5236
    @luckyfat52365 ай бұрын

    Thank you so much ❤❤❤❤❤❤

  • @user-pb4pe5qe3y
    @user-pb4pe5qe3y Жыл бұрын

    thank you for fabulous lesson. Your lecture is indispensable for me

  • @user-oh5pl2bo2s
    @user-oh5pl2bo2s3 ай бұрын

    thank you very much doctor

  • @naturesoundshome9864
    @naturesoundshome9864 Жыл бұрын

    Please do us myeloproliferative neoplasms

  • @sumayamaxamed3304
    @sumayamaxamed330411 ай бұрын

    Thanks so much sir

  • @tatianazhiglova5924
    @tatianazhiglova59249 ай бұрын

    Thank you !

  • @anabelfulterer2377
    @anabelfulterer23773 ай бұрын

    Thank you for this videoo!

  • @maggieensley8819
    @maggieensley88199 ай бұрын

    RN here recently diagnosed with CLL/SLL under investigation for large B cell lymphoma, need a FISH study(you didn’t mention) Now I know Im Rai 2 symptomatic with the typical B symptoms. Recent 50 lbs weight loss in 6 mths, lots of abdominal symptoms and pain. FYI My other presenting initial symptom was thoracic back pain spinal cord compression along with the lymphocytosis . Thats a big problem. Knowledge is power! Fantastic lecture Im gonna send it to my GP😂❤Thank you!!

  • @grammyg8x

    @grammyg8x

    3 ай бұрын

    @maggieensley8819 your story sounds like mine. I have had a weird rash for 1.5 years. It was called psoriasis, but nothing helps. Now it's on my back. Recently got intracellular nutrient test back and shows anemic. I've struggled with fatigue. So, next step is bloodwork. Has anyone experienced rashes? I am in my early 60's.

  • @blessingsunday151
    @blessingsunday15111 күн бұрын

    Thank you for this presentation, God bless you 🙏

  • @user-rn7gp8ms8b
    @user-rn7gp8ms8b Жыл бұрын

    thank you for your supporting us please we need explanation about chronic myelogenous leukemia ❤❤❤

  • @eras2730
    @eras2730Ай бұрын

    Best video on CLL ever!

  • @rozanahwirt1311
    @rozanahwirt131114 күн бұрын

    You are brilliant!

  • @roselily3269
    @roselily3269 Жыл бұрын

    Thank you so much Zack you are the best

  • @danielapau3232

    @danielapau3232

    Жыл бұрын

  • @jovinkomba2908
    @jovinkomba290811 ай бұрын

    Very Useful Bravooo your soo Good ❤️❤️

  • @sllvax448
    @sllvax448 Жыл бұрын

    THANKS A LOT 🫶🫶🫶🫶🫶

  • @mohammadsaad539
    @mohammadsaad5399 ай бұрын

    Thank you so much sir…….

  • @obadadabbour2043
    @obadadabbour2043 Жыл бұрын

    AMAZING!!!

  • @user-cq4tk1kw4s
    @user-cq4tk1kw4s5 ай бұрын

    thank you!

  • @salama7758
    @salama775824 күн бұрын

    You're the best, you helped in pathology

  • @andreiafn
    @andreiafn11 ай бұрын

    THANK YOU ❤❤

  • @akozrar1330
    @akozrar1330 Жыл бұрын

    thanks Dr

  • @acheampongjoshua5781
    @acheampongjoshua5781 Жыл бұрын

    am from africa , ghana your videos help me alot

  • @ahutamorris
    @ahutamorris Жыл бұрын

    Watching from Nairobi, Kenya. Nice video prof, am gaining a lot from you and now it's almost 5yrs since I started your lessons. Ninja Nerd...... please give us certificates 😂😂 and we pay for it.

  • @leonchikumba
    @leonchikumba3 ай бұрын

    Thank you

  • @younusessack9315
    @younusessack931510 ай бұрын

    Brilliant

  • @petahayden4412
    @petahayden44122 ай бұрын

    You are an absolute legend ❤️

  • @alejacarrasquillo1291
    @alejacarrasquillo12915 ай бұрын

    LOVE!!! thanks

  • @CaseyBurnsInvesting
    @CaseyBurnsInvesting3 ай бұрын

    Great videos my friend

  • @doctortidbits
    @doctortidbits5 ай бұрын

    Maybe i'm wrong but you look under the weather in this video. Hope you are doing well. You are an incredible teacher! God bless you!! Prayers your way!

  • @chisulochisanga7809
    @chisulochisanga78096 ай бұрын

    The best videos on Leukemia's😊

  • @mariakara4848
    @mariakara4848 Жыл бұрын

    谢谢您!🌸

  • @mohammedhealing
    @mohammedhealing Жыл бұрын

    Thank u ninja You're the best bcz of u I wanna be neurologist ❤

  • @cathleenpatane6855
    @cathleenpatane68558 ай бұрын

    Thanks

  • @Z.almagdi
    @Z.almagdi21 күн бұрын

    Commenting to support

  • @hadeel1822
    @hadeel1822Ай бұрын

    I love this man

  • @bunny8352
    @bunny8352 Жыл бұрын

    love these

  • @medstudentdaily2269
    @medstudentdaily22696 ай бұрын

    شكراً ❤

  • @humanbeing3177
    @humanbeing3177 Жыл бұрын

    A legend indeed

  • @sophiaiwuoha1496
    @sophiaiwuoha14968 ай бұрын

    Love you Doc😘

  • @NomaMPride
    @NomaMPride2 ай бұрын

    Thank you for the video really appreciate it, I tried reading Davidson but didn’t understand

  • @user-vj2wt7jh7j
    @user-vj2wt7jh7j11 ай бұрын

    I have atypical CLL with multiple paraneoplastic syndromes starting with a massive Pulmonary Embolism with cor pulmonale in 2108 spent a week in the ICU. Most of my paraneoplastic syndromes have been neurologic. I have found that oncologists seem to know very little about paraneoplastic syndromes and just ignore my symptoms. I never get any answers and have to research everything myself. I delt with almost a year of appendicitis level lower abdominal pain with no help or answers. It seemed to be a vascular type pain which fit angioedema in my colon which is occassionaly seen with CLL. I have seen peripheral angiodema in the past and the pain was identical to what my patients complained of. I am trying to figure out how to get oncologists to listen, or find an oncologist who knows atypical CLL.

  • @user-vj2wt7jh7j

    @user-vj2wt7jh7j

    8 ай бұрын

    I am looking for help and get none. I also get no answers, which is very frustrating. I have to research everything myself to get answers. My oncologists don't even try. It is extremely frustrating! I have had to find treatments on my own with no help from oncologists.

  • @imanetargui3836
    @imanetargui3836 Жыл бұрын

    You are amazing❤️🥰

  • @avapond5682
    @avapond56826 ай бұрын

    You said please twice. So here I am. and I get to say a big thank you!

  • @gamingwala2
    @gamingwala2 Жыл бұрын

    Please make a video on tissue it's really helpful for me and many other medical students. It's a humble request Zach 🥺

  • @shirleycisneros2948
    @shirleycisneros2948 Жыл бұрын

    Justo lo que estoy estudiando ahora ❤❤❤

  • @ahmedeldimllawi5092
    @ahmedeldimllawi50925 ай бұрын

    ur awesome, i am a hematology fellow and the ASH SAP is complicated i need someone to simplify it for me so thank you for that really

  • @mercymaeda2237
    @mercymaeda2237 Жыл бұрын

    You teach better than my lecturer

  • @azlanalikhan6043
    @azlanalikhan60435 ай бұрын

    Please do an overview video on leukemias and lymphomas.

  • @PureLove1818
    @PureLove18188 ай бұрын

    I have to watch this 10 more times to get it all down, but my mom was just diagnosed at 74. We meet with her med team tomorrow. Ill have lots of questions for them because of the knowledge in this video. Im armed and ready to fight! (With knowledge) xxoo thank you to the creator of this video.

  • @ula7254
    @ula725410 ай бұрын

    I am jealous of u bro, great work ❤ we hope you have a great life with lot of beautiful blessings ❤