Calcineurin Inhibitors (Tacrolimus and Cyclosporine) IL2 - Mechanism of action, adverse effects
Buy PDFs here: armandoh.org/shop
I design my own shirts please support :)
"Calcineurin inhibitors such as tacrolimus and cyclosporine are immunosuppressants. They are used mainly to prevent organ transplant rejection in combination with mycophenolate and steroids as well used in severe atopic dermatitis. They are not really used as much for rheumatologic conditions any more, possibly for lupus nephritis. Calcineurin inhibitors are also used for the treatment of graft versus host disease in bone marrow transplant recipients. Calcineurin inhibitors inhibit the synthesis of IL2."
Where do I get my information from: armandoh.org/resource
Facebook:
/ armandohasudungan
Support me:
/ armando
Instagram:
/ armandohasudungan
Twitter:
/ armandohasudung
SPECIAL THANKS:
Patreon members
Пікірлер: 41
Highly appreciate those like you who do not subject people to a 20 second intro for a serious study topic
We should also know the mnemonic: Hot T Bone stEAk Hot (fever) = IL-1 T cell simulator = IL-2 Bone marrow stimulator (sim to GM-CSF) = IL-3 IgE = IL-4 and IgA = IL-5 Thanks for the short and very informative video. I have just subscribed. Btw, please share with me what apps or softwares that you use to draw, to make your videos? Thanks!
@thivz6630
Жыл бұрын
Thank you for this
Awesome! Very clear and easy explanation.
thank you for your very simple explaination
Thank you so much for the video,Found very useful for my Pharmacy study..
Hello Armando, I came here because I wanted to comment in a recent video, so it’s more probable, that you will read it. I needed to understand how do interact Calcium levels, vitamin D and PTH, so I went to your video, which explains it. I have multiple sclerosis and I’m following a therapy called Coimbra Protocol, which is based in a few pillars: - Ultra high Dosis of vitamin D3 (50.000 units in my case to set my immune system back to “default”) - Very low calcium diet (to avoid to much calcium to filter) - More than 2,5 L of liquids per day (to avoid high concentration in Urine) - Regular sport (to build bone tissue up) - Avoid stress and unhealthy food My question is, *why, when a low level of Calcium in blood stimulates the production, did my PTH level increased from 21 pg/ml to 31?* The second time I checked this value, it only increased from 19,5 to 21 in the same time frame. I ate a bit more calcium-rich food in this time, so my body should have absorbed way more calcium. I just don’t get it A video about the coimbra protocol, how it works and what are its dangers, would be really nice. I can provide you with sources of information, if you want ;) I also would share it, with MS-Groups of Facebook, because it would be reeeeeally interesting to see how it works internally.
Filling some of the gap of sketchy pharm. Nice!
T hanks armando hasudungan channel.
Wow ,! Its fun way to learn . Thank you sir
Amazing video, Thank you
Amazing. Do you have a video on mycophenolate, azathioprine, and other immunosuppressants?
Thanks , you're awesome♥️
Very informative😊
I have watched your videos for the past 10 years. I just realised that I have not clicked the subscribe button 😅😅😅 sorry, the progress is amazing. It almost feels like seeing someone grow.
Bro you can see the matrix...this channel is insanely great....
life-saving video
Well explained
Wowwwwwwwie😍. Thankyou sir!
Amazing 👏🏻
Wow , amazing
Thanks you so much
thank you
Super!!!
Keep it up ❤❤❤
What's your effect or tools to make this video plz 😍😍😍
sir please make the full digation video
Mechanism of action of calcineurin inhibitors is suppressing synthesis of pro-inflammatory cytokines. In the cytoplasm of the target cells, pimecrolimus and tacrolimus bind to the intracellular protein macrophilin-12, also called FKBP (FK506-binding protein). Similarly, cyclosporine A binds to cyclophilin.👍
Plz upload physics and chemistry lecture
Thank you for accepting the request on posting a videos on immunosuppressants, even if you haven't read my previous comment..still thanks😇❤
Genial
Best
Sir , I am teaching in Jr. College so need to take online classes coz of this pandemic. Can you plz tell me what have you used here to get such screen.? Is it a App? Of Device ? My issue is we don't get clearly when i stand in front of board and teach. So this way of yours is best . Can you guide plz
Can you also make a video about Tuberculosis please? The pathophysiology is very complex and difficult to understand by reading alone
👏👏
Millions subs ..still less likes
🌹🌹
I looked up this video just to find out how to pronounce tacrolimus