Beta Oxidation of Fatty acids Made Simple-Part 1

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Beta Oxidation of Fatty acids Part 2
• Beta Oxidation of Fatt...
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In biochemistry and metabolism, beta-oxidation is the catabolic process by which fatty acid molecules are broken down[1] in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain. It is named as such because the beta carbon of the fatty acid undergoes oxidation to a carbonyl group. Beta-oxidation is primarily facilitated by the mitochondrial trifunctional protein, an enzyme complex associated with the inner mitochondrial membrane, although some fatty acids are oxidized in peroxisomes.
Fatty acid catabolism consists of:
Activation and membrane transport of free fatty acids by binding to coenzyme A.
Oxidation of the beta carbon to a carbonyl group.
Cleavage of two-carbon segments resulting in acetyl-CoA.
Oxidation of acetyl-CoA to carbon dioxide in the citric acid cycle.
Electron transfer from electron carriers to the electron transport chain in oxidative phosphorylation.
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    @MEDSimplified

    6 жыл бұрын

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    5 жыл бұрын

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    @ashvinbaldania

    4 жыл бұрын

    Too many faults in the video !

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    3 жыл бұрын

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    Wasted four hours trying to decipher what my professor meant to teach me about Beta-Oxidation. This channel does it in about ten minutes. Thank you!

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    @RohitPant044 жыл бұрын

    Mitochondria are constantly cycling throughout the neuron. Some are stationary while others are moving down the arms of the cell to assume their proper position. So, while they are complex in their machinery when it comes to neurons we can't deny there presence there. Thanks!

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    @varshitha7324

    3 жыл бұрын

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    @aegislegis7551 Жыл бұрын

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    @bodycareforhealth86566 жыл бұрын

    so simply and concisely explained, I now understand the carnitine shuttle. you have excellent educational skills to enlighten students that have to cope with ridiculous complicated notes that do not convey what it is we have to know. thank you, thank you, thank you. I can now move forward. karen

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    2 жыл бұрын

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    Nervous tissue actually has a lot of mitochondria especially neurons,for synthesis of neurotransmitters,exocytosis,neurotransmitter uptake pump,etc

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    @mohammedm7006

    4 жыл бұрын

    Samantha Gonah yep, he failed a bit there. Good you noticed, i noticed it aswell

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    4 жыл бұрын

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    4 жыл бұрын

    He said lipase work in adipocytes ! Not correct .

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    @minty_0692

    3 жыл бұрын

    @@ashvinbaldania what other mistakes are in the video?

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    @soukainayounes98834 жыл бұрын

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    @MEDSimplified

    7 жыл бұрын

    +Mohamed Kamel Thank you for your appreciation Kamel

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    @ridaiftikhar41656 жыл бұрын

    this is truly amazing..i thought i could never understand the fatty acids but u explained literally well..in both 1 nd 2 part of beta oxidation..God bless u..👍

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  • @MEDSimplified

    @MEDSimplified

    Жыл бұрын

    Glad i was able to help

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    @tainamoore917 ай бұрын

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    @MEDSimplified

    7 жыл бұрын

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    nice job guys easily understood the concept of beta oxidation

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    @harrypillay92884 жыл бұрын

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  • @MEDSimplified

    @MEDSimplified

    4 жыл бұрын

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    @MEDSimplified

    7 жыл бұрын

    +Zarlish Khan I always struggled with biochemistry like you Zarlish. Glad my videos helped u!

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    @zarlishkhan2787

    7 жыл бұрын

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    @charujamnotia91106 жыл бұрын

    thanku so much sir... best explanation ☺️

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  • @KoaPalakikoHawaii
    @KoaPalakikoHawaii2 жыл бұрын

    6:35 for generalization The enzyme is called Carnitine Acyl Transferase 1

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    @asserm.80475 жыл бұрын

    "nervous tissue doesnt have mitochondria" this knocked mw out

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    Thank you so much for all your help please make more videos on enzymology ,

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    @zoologywithadgad-xb6lm5 ай бұрын

    best explanation ever i have seen

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    @GautamKumar-hz1gy5 жыл бұрын

    Best vedio.. ..thanku sir

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    @chamomile36202 жыл бұрын

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    @chemophobicc6 жыл бұрын

    Super video really simple way of teaching thanks sir

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    @bintaibrahim20256 жыл бұрын

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    @akkuvines35845 жыл бұрын

    Love your videos

  • @hraqhraq
    @hraqhraq3 жыл бұрын

    1:25 according to your explanation it should be alpha-beta oxidation not beta. You forgot to mention to mention that fatty acyl CoA will undergo 4 reactions with 4 different enzymes that will be 1. Dehydrogenase 2. Hydrolase 3. Dehydrogenase 4. Thiolase Now the step 2 and 4 attack the Beta Carbon thus it is called beta oxidation ( first attack will add OH group and the 2nd attack will add oxo group), hope this will explain why

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    @tuljagobburu9117 Жыл бұрын

    Very helpful video, thank you so much !

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    @asayel125 жыл бұрын

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    @sindhu65105 жыл бұрын

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  • @MEDSimplified

    @MEDSimplified

    7 жыл бұрын

    +Paul Awad I am glad i was able to helo

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    @priyasontakke88136 жыл бұрын

    Best explanation!! Thank u

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    @assholapure7 жыл бұрын

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  • @MEDSimplified

    @MEDSimplified

    7 жыл бұрын

    +Aakash sholapure i m so glad. Thanks

  • @MEDSimplified

    @MEDSimplified

    7 жыл бұрын

    +Aakash sholapure. You are welcome Aakash

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    @mansisart21243 жыл бұрын

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  • @cowinlk3074
    @cowinlk30743 жыл бұрын

    I understood abt fatty acid oxidation even before my lecture😍😍😍

  • @eightafied
    @eightafied7 жыл бұрын

    God bless you!!!! Thank you so much!!

  • @MEDSimplified

    @MEDSimplified

    7 жыл бұрын

    +Sandra Lee You are welcome Sandra!

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    @abhisheknagar47505 жыл бұрын

    Very conceptual learning plz keep it up

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    @geetarautela15 жыл бұрын

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    @user-tw7lc1hz9i7 жыл бұрын

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    @MEDSimplified

    7 жыл бұрын

    +William Butacu i love you too william.. :)

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    Giving a great competition to shomu's biology

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    @geresukarbaso46215 жыл бұрын

    i learned from video very much.

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    @mugambiismbaya4 жыл бұрын

    great video, I learned a lot

  • @tobinos8018
    @tobinos80187 жыл бұрын

    You simplified the topics and made it easy to comprehend. You are one of the few indians(if im cprrect) whose English accent is clear.God bless you sir.

  • @MEDSimplified

    @MEDSimplified

    7 жыл бұрын

    +Tobi Nos thank you so much. Nd i guess u r rite. 😊

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    @Priyankkush74 жыл бұрын

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    @secret43545 жыл бұрын

    Very nice