Beta Oxidation of Fatty acids Made Simple-Part 1
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Beta Oxidation of Fatty acids Part 2
• Beta Oxidation of Fatt...
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In biochemistry and metabolism, beta-oxidation is the catabolic process by which fatty acid molecules are broken down[1] in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport chain. It is named as such because the beta carbon of the fatty acid undergoes oxidation to a carbonyl group. Beta-oxidation is primarily facilitated by the mitochondrial trifunctional protein, an enzyme complex associated with the inner mitochondrial membrane, although some fatty acids are oxidized in peroxisomes.
Fatty acid catabolism consists of:
Activation and membrane transport of free fatty acids by binding to coenzyme A.
Oxidation of the beta carbon to a carbonyl group.
Cleavage of two-carbon segments resulting in acetyl-CoA.
Oxidation of acetyl-CoA to carbon dioxide in the citric acid cycle.
Electron transfer from electron carriers to the electron transport chain in oxidative phosphorylation.
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@MEDSimplified
6 жыл бұрын
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@lovemashup2103
5 жыл бұрын
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@ashvinbaldania
4 жыл бұрын
Too many faults in the video !
@aditirafalia1672
3 жыл бұрын
@@ashvinbaldania Hey I am studying for an exam, so can you please let us what is wrong in the video?
@bransonkingston600
3 жыл бұрын
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Wasted four hours trying to decipher what my professor meant to teach me about Beta-Oxidation. This channel does it in about ten minutes. Thank you!
Mitochondria are constantly cycling throughout the neuron. Some are stationary while others are moving down the arms of the cell to assume their proper position. So, while they are complex in their machinery when it comes to neurons we can't deny there presence there. Thanks!
@varshitha7324
3 жыл бұрын
Thanks for the comment. I am budding medico. I didn't noticed it.
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@ktxoxo183
2 жыл бұрын
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Nervous tissue actually has a lot of mitochondria especially neurons,for synthesis of neurotransmitters,exocytosis,neurotransmitter uptake pump,etc
@mohammedm7006
4 жыл бұрын
Samantha Gonah yep, he failed a bit there. Good you noticed, i noticed it aswell
@collinmackey2391
4 жыл бұрын
I was thinking the same thing and thought I was going crazy, thx for reassuring
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4 жыл бұрын
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@ashvinbaldania
4 жыл бұрын
He said lipase work in adipocytes ! Not correct .
@minty_0692
3 жыл бұрын
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@MEDSimplified
7 жыл бұрын
+Mohamed Kamel Thank you for your appreciation Kamel
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@MEDSimplified
Жыл бұрын
Glad i was able to help
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@MEDSimplified
7 жыл бұрын
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@MEDSimplified
4 жыл бұрын
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@MEDSimplified
7 жыл бұрын
+Zarlish Khan I always struggled with biochemistry like you Zarlish. Glad my videos helped u!
@zarlishkhan2787
7 жыл бұрын
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6:35 for generalization The enzyme is called Carnitine Acyl Transferase 1
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1:25 according to your explanation it should be alpha-beta oxidation not beta. You forgot to mention to mention that fatty acyl CoA will undergo 4 reactions with 4 different enzymes that will be 1. Dehydrogenase 2. Hydrolase 3. Dehydrogenase 4. Thiolase Now the step 2 and 4 attack the Beta Carbon thus it is called beta oxidation ( first attack will add OH group and the 2nd attack will add oxo group), hope this will explain why
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@MEDSimplified
7 жыл бұрын
+Paul Awad I am glad i was able to helo
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@MEDSimplified
7 жыл бұрын
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@MEDSimplified
7 жыл бұрын
+Aakash sholapure. You are welcome Aakash
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@MEDSimplified
7 жыл бұрын
+Sandra Lee You are welcome Sandra!
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@MEDSimplified
7 жыл бұрын
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@MEDSimplified
7 жыл бұрын
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