you've made a seemingly complicated process very easy to understand, thank you!

It's wonderful bro....now I,m feeling that it,s so easy to understand it

Now that I see it, I understand. Thank you !!

Thank you🥰

super helpful thank you

Thank you so much

Thank you

i think N Glycolase does not remove the base it just identifies the wrong base. ap endonuclease cleaves the region and the base will be removed from 5 exonuclease than comes polyemrase one with the base and finally dna ligase to repair the cleavage.

@umbra9029

Жыл бұрын

That's exactly what happens if I'm not mistaken

@sameerhussain3709

Жыл бұрын

no he is correct you guys are wrong..... read books 📚📚📚

@becheaachi

7 ай бұрын

You think wrong man...glycosylase breaks the n-glycoside bond between the base and sugar

Thank you so much you are really goog to explain.

thank you

Excellent 👌

Very nice 🙏👍

It's helpful ☺️

Amazing 🤩😍

thank you so much

Thankyou sir

saved my life

Thanks . L am Azerbaijan💪🇦🇿

Great

best video ❤

the animation shows a 3' to 5' DNA pol. but the narration say it was a 5' to 3' DNA pol, so which one is it?

@allaboutakoo

5 ай бұрын

dna is always built 5 - 3 prime

@cygthings

3 ай бұрын

The overall direction is 5' to 3' but in that instance, the exposed ends are 3'-OH on the left side and 5'-P on the right side.

@Phoenix-np1iu

2 ай бұрын

if i understand correctly, each nucleotide has a 5 prime end and a 3 prime end. the new nucleotide is added so that its 5 prime connects to the 3 prime of the one before it

Weldone

❤❤

When DNA glycosylases remove modified base then already 3'OH nd 5'P site open so AP endoculease what actually did??🤔🤔

@tanvirahmed-rr7vt

2 жыл бұрын

Nope the phosohodiester bond is not broken as the nucleotide moeity( without the base) still remains at the region..

Weldone