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Apoptosis - Introduction, Morphologic Changes and Mechanism

#apoptosis #pathology #cellinjury
Apoptosis, also called “programmed cell death” is the process where the cell regulates its own death through the production of certain enzymes. These enzymes cause degradation of nuclear and cytoplasmic DNA and the cell breaks into fragments called apoptotic bodies. Apoptotic bodies are then gobbled up by phagocytes.
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References and further reading:
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins Basic Pathology. 10th ed. Elsevier; 2018.
💡Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran - Pathologic Basis of Disease. 8th Edition. Saunders Elsevier; 2010.
💡Abbas AK, Litchman AH, Pillai S. Cellular and Molecular Immunology. 8th Edition. Saunders Elsevier; 2015.
💡Elmore S. Apoptosis: A Review of Programmed Cell Death. Toxicol Pathol. 2007; 35(4): 495-516.
💡Apoptosis and Signal Transduction. Available at www.wehi.edu.au/wehi-tv/apopt....
💡Apoptosis. Available at www.onkoview.com/das-buch/kapi....
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Пікірлер: 179

  • @GlidyBun
    @GlidyBun3 жыл бұрын

    Holy crap, Indians saving the day once again! Thank you!

  • @Claudiannamani
    @Claudiannamani4 жыл бұрын

    I’ve never seen Robbins and Cotran textbook explained this concisely and graphically! Brilliant

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    Thank you very much!

  • @nikitapaul3181
    @nikitapaul3181 Жыл бұрын

    This is such an underrated video. Thank you so much for this beautiful animation explanation with easy words. Everytime i open this chapter it reminds me of this video and boom the concept is crystal clear.😅

  • @HackDentistry

    @HackDentistry

    Жыл бұрын

    Thanks very much for the feedback. Glad you found the video useful :)

  • @selvam5755
    @selvam57552 жыл бұрын

    Please Reupload the videos. It was great help for me to study and remember. Especially oral pathology. Pls do re add the videos.

  • @shizashah6044
    @shizashah60442 жыл бұрын

    Amazing!!! Please make more pathology videos...these lectures are amazing and easy to understand 💯💯💯

  • @tejasvinimehta6198
    @tejasvinimehta61983 жыл бұрын

    A wonderful way of explanation and presentation. JUST WOW!!! Loved it !!! :)

  • @enderknight3779
    @enderknight3779 Жыл бұрын

    thank you so much for this amazing explanation I hope to see more videos like this one!

  • @azizullah7171
    @azizullah71713 жыл бұрын

    Such an amazing explaination sir!!! You made my seven minutes precious!! Thanks

  • @kaviyarasisivaraman9688
    @kaviyarasisivaraman9688Ай бұрын

    very much useful thank you! awesome animation, easy to understand

  • @naqiraza8646
    @naqiraza86462 жыл бұрын

    ur Explaination with animation is amazing

  • @uroojarshadkhan4031
    @uroojarshadkhan40313 жыл бұрын

    Thank you so much sir 😊 you have made this topic so easier to understand.

  • @AliRaza-jx5fr
    @AliRaza-jx5fr2 жыл бұрын

    Perfectly explained! Thank you so much

  • @sourishrathi3929
    @sourishrathi39292 жыл бұрын

    This is amazing! Thank you so much!

  • @DusktillDawn-09
    @DusktillDawn-094 ай бұрын

    I was so worried about understanding this topic, but you made it so easy!!!! Thankyouu . Keep making such pathology videos

  • @arijoybhattacharjee6039
    @arijoybhattacharjee60393 жыл бұрын

    Was very informative and easy to understand... Waiting for more Pathology videos

  • @LA-ug6ol
    @LA-ug6ol8 ай бұрын

    Cant be more clear !! Tysm GOAT 🙏🏻🙏🏻❤️❤️

  • @suhasinimallick2130
    @suhasinimallick21304 жыл бұрын

    very good video... thank you!

  • @Mumtaztaiba
    @Mumtaztaiba2 жыл бұрын

    Absolutely brilliant ! My teacher couldn't explain it for the last 3 days..but u ;)💯🙌

  • @kumarbibek3502
    @kumarbibek35023 ай бұрын

    Excellent animation and explanation ❤

  • @user-bm7dg6nm8x
    @user-bm7dg6nm8x4 жыл бұрын

    Thank you so much , it was great

  • @aiswaryaaishu3788
    @aiswaryaaishu37882 жыл бұрын

    Well explained..easy to understand..please keep uploading more videos

  • @aazzmmm8069
    @aazzmmm80692 жыл бұрын

    Omggggg such a great explanation. I'm amazed.

  • @mridulproyash5691
    @mridulproyash56915 жыл бұрын

    Very Nice Presentation.Thanks a Lot.

  • @maybethisthis8280
    @maybethisthis82803 ай бұрын

    Thank you. I understood this morning cause of you

  • @halahali8108
    @halahali81083 жыл бұрын

    Soooooo amazing explanation .. Thank you 😊

  • @s.s8925
    @s.s89257 ай бұрын

    Thanks a lot for such precise explanation...

  • @medicalphilia840
    @medicalphilia8402 жыл бұрын

    Really Awesome sir ! Please continue this work to explain more complex topics into simpler....This video is worth to subscribe and like. Thank You so much !

  • @rubabmushtaqnawab8613
    @rubabmushtaqnawab86133 жыл бұрын

    Please post more pathology videos on inflammation and cell injury.. these are really helpful

  • @Crazy7speed
    @Crazy7speed3 жыл бұрын

    VERY NICE PLEASE KEEP MAKING THESE TYPE OF VIDEOS👍

  • @nityarai2909
    @nityarai2909Ай бұрын

    Really appreciate your knowledge and effort in making this video thank you sir ❤

  • @Ram-yn3b
    @Ram-yn3b2 жыл бұрын

    Thanks sir!!

  • @sabeehamehaboob6397
    @sabeehamehaboob63973 жыл бұрын

    Awesome explanation and animation

  • @aaratibhusal6486
    @aaratibhusal64863 жыл бұрын

    thank you so much sir . you saved us..

  • @excalibur9768
    @excalibur97684 жыл бұрын

    Absolutely brilliant explanation! Thank you so much, Sir.

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    Thanks very much! Our pleasure!

  • @shabnairshad2970
    @shabnairshad29702 жыл бұрын

    Cleared final year exam exam.. Your Videos helped me a lot to achieve this... Thank you so much sir..and happy teachers day also 😍

  • @HackDentistry

    @HackDentistry

    2 жыл бұрын

    Very glad. Thank you so much for the wishes.

  • @hrithishc6398
    @hrithishc63987 ай бұрын

    Excellent video ❤‍🔥❤‍🔥

  • @shrutiverse7149
    @shrutiverse7149 Жыл бұрын

    Great work 👏💕

  • @priyankapathak4665
    @priyankapathak46652 жыл бұрын

    Abosulte way of explanation and presentation. Simple n consize.Thank u so much

  • @CogniBytes123
    @CogniBytes123 Жыл бұрын

    Thanks for the video ✨❤️

  • @thanushree2684
    @thanushree26844 ай бұрын

    This video is just awesome Thank you soooo muchhh !!!! I would really like to know how could you comprehend a topic so lucidly like this !!!?

  • @humzahpostwala5525
    @humzahpostwala55253 жыл бұрын

    great work

  • @salmakhan11112
    @salmakhan111122 жыл бұрын

    Amazing Sir

  • @suchitrasardar-7659
    @suchitrasardar-76593 жыл бұрын

    Loved ur explanation...all doubts clear now😁😍

  • @suneel4422
    @suneel44228 ай бұрын

    Glad I found this video ❤️

  • @seqono1903
    @seqono19033 жыл бұрын

    Brilliant 👏🏼🖤.

  • @abhisheksarkar5559
    @abhisheksarkar55592 жыл бұрын

    It was really very helpful to understand the apoptosis

  • @nianni9809
    @nianni98092 жыл бұрын

    thank you so much

  • @thedarklamp02
    @thedarklamp02 Жыл бұрын

    Liked it very much , thanks ❤️

  • @bhavishapatel8459
    @bhavishapatel8459 Жыл бұрын

    ❤Such a simplified explanation❤ Thankyou 😊

  • @zukhrufnoor7154
    @zukhrufnoor71542 жыл бұрын

    Very very helpful vedio !! Thanku very much ❤

  • @samariddintirkashevMCT
    @samariddintirkashevMCT2 жыл бұрын

    I think this is the best video by apoptosis

  • @komaldiptianandmaisuriya4301
    @komaldiptianandmaisuriya43014 жыл бұрын

    Thanks understood everything

  • @drhawaanwar1267
    @drhawaanwar12673 жыл бұрын

    well explained.. very helpful.. ❤❤❤❤🧡🧡

  • @Gypsy_soul13
    @Gypsy_soul133 жыл бұрын

    Thanks man ♥️

  • @aashikaam6627
    @aashikaam66272 жыл бұрын

    Thank you very much sir

  • @mohammadassaf2715
    @mohammadassaf27153 жыл бұрын

    Great job

  • @srushtipatel9088
    @srushtipatel90884 жыл бұрын

    Great work❤️......Please make more videos to simplify pathology ....☺️☺️☺️

  • @alfiafarooqui5947
    @alfiafarooqui59473 жыл бұрын

    Thank you ❤️

  • @kanchanbhagat9256
    @kanchanbhagat92562 ай бұрын

    Thank you

  • @mariammuqadas437
    @mariammuqadas4373 жыл бұрын

    Best everrrrr video..

  • @DR.SAHARSHA
    @DR.SAHARSHA4 жыл бұрын

    Very nice explanation.. saw this just half an hour before my exam.. and even this less time i understood very well.. thank you

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    We are very happy the video helped. Cheers and all the very best!

  • @salmakhan11112
    @salmakhan111122 жыл бұрын

    Sir kindly upload more videos about pathology.... your way of conveying lacture is fabulous

  • @madhu9832
    @madhu98328 ай бұрын

    Good vedio thankyou ✨

  • @Happysoul_007
    @Happysoul_0072 жыл бұрын

    Very nice and helpful video 🙏🙏

  • @Andromeda-ii8gz
    @Andromeda-ii8gz4 жыл бұрын

    Brilliant work. Thank you sooo much sir. May god bless you 😄❤👍

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    Thank you so much!

  • @blackstar6908
    @blackstar69082 жыл бұрын

    A very lot thanks for this teacher

  • @JasleenKaur-xi3eu
    @JasleenKaur-xi3eu Жыл бұрын

    Loved it 🥰

  • @zainabcassim6010
    @zainabcassim6010 Жыл бұрын

    Amazing. Thank you very much for explaining all three mechanisms in such a small time in a easy way to understand. I became a new subscriber to your channel as to this amazing video. From srilanka

  • @shalinikurkule7402
    @shalinikurkule7402 Жыл бұрын

    Great it is best ever,so much helpful .plz make more videos on pathalogy

  • @interestingstuff2043
    @interestingstuff20432 жыл бұрын

    Nice explanation sir

  • @adrianciobotaru8770
    @adrianciobotaru877010 ай бұрын

    Great video! It helped me understand better the process of apoptosis.

  • @HackDentistry

    @HackDentistry

    10 ай бұрын

    Happy the video was helpful :)

  • @drkarthikm8738
    @drkarthikm87383 жыл бұрын

    Excellent 👌

  • @sakshisood7375
    @sakshisood73753 жыл бұрын

    Doing 2nd year mbbs...best video ever seen

  • @riturajbaruah_
    @riturajbaruah_3 жыл бұрын

    Thankyou sooo much

  • @farzanatanjil3070
    @farzanatanjil30703 жыл бұрын

    Excellent

  • @Maria-xg7xe
    @Maria-xg7xe2 жыл бұрын

    Mashallah so amazing thank u 🙏🏻

  • @anantikarai8245
    @anantikarai82452 жыл бұрын

    That phagocyte sounds like me eating lays 😂 Thanks for the video 🙂

  • @dr.sapnayadav4023
    @dr.sapnayadav40233 жыл бұрын

    Amazing🤩

  • @yogeshwarijagadeesh3930
    @yogeshwarijagadeesh39304 жыл бұрын

    Really nice video 👌👌 this helps me a lot for revising the concepts for viva exams, thank you much😊

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    We are very glad it helps! All the very best!

  • @Himanshu-pj4wk
    @Himanshu-pj4wk3 жыл бұрын

    Just amazing wow

  • @vasanthapriyadoc8588
    @vasanthapriyadoc85883 жыл бұрын

    Kudos to u sir, understood the concept Bcoz u!

  • @HackDentistry

    @HackDentistry

    3 жыл бұрын

    I am very glad :)

  • @riteshvishwakarma475
    @riteshvishwakarma4759 ай бұрын

    U r a genius 🙌

  • @shaiklathifmunnisha1426
    @shaiklathifmunnisha14262 жыл бұрын

    Tq so much sir

  • @taniasagheer-kw3sr
    @taniasagheer-kw3sr Жыл бұрын

    Well explained 💯👏🏼

  • @sakeena313
    @sakeena3133 жыл бұрын

    This is incredible sir👍 Exceptional 👍 Thanks a lot sir

  • @HackDentistry

    @HackDentistry

    3 жыл бұрын

    Thanks very much for the feedback. Glad it was useful.

  • @anandsagar2590
    @anandsagar25907 ай бұрын

    You made my day, tomorrow is my exam and I understood everything

  • @HackDentistry

    @HackDentistry

    7 ай бұрын

    All the very best ✌

  • @jamjamredvelvet
    @jamjamredvelvet3 жыл бұрын

    Thanks 👌

  • @juanignaciomathieu5390
    @juanignaciomathieu53903 жыл бұрын

    Gracias por salvarnos y por tu magia que nos brindas dia tras dia. Sin exagerar, no?, es un honor apreciar y escuchar tus conocimientos y sabidurias adquiridas con tanto esfuerzo en el famosísimo Robbins and Cotran's Book. We love you!

  • @HackDentistry

    @HackDentistry

    3 жыл бұрын

    Gracias por sus amables palabras. Me alegro mucho que lo encuentre útil.

  • @swapnadeep641
    @swapnadeep6413 жыл бұрын

    Oh what explain heart touching

  • @Loveinvibes3526
    @Loveinvibes3526 Жыл бұрын

    I love your method of teaching god bless u 💓

  • @HackDentistry

    @HackDentistry

    Жыл бұрын

    Thank you Sana. Glad you find the video useful!

  • @monetweldon8672
    @monetweldon86723 жыл бұрын

    This is a wonderful explanation. I do have one question, at 4:51 where you state FADD adheres to the cytoplasmic end of at least 3-4 Fas ligands, did you mean 3-4 Fas receptors? I'm not understanding if the receptor has to bind to multiple Fas ligands or if FADD binds to multiple ligands or what is going on there. That part was a little confusing but overall this was a very informative video. Thank you for making it.

  • @HackDentistry

    @HackDentistry

    3 жыл бұрын

    You are right. That was a mistake there. I meant FADD binds to Fas receptors. Nice find. Thanks for pointing it out.

  • @user-ek7cy2lx2t
    @user-ek7cy2lx2t3 жыл бұрын

    Best explanation I have ever found for apoptosis, thank a lot

  • @HackDentistry

    @HackDentistry

    3 жыл бұрын

    Glad it was helpful!

  • @abdullahmelhim92

    @abdullahmelhim92

    3 жыл бұрын

    ياليل ناشب لي في كل مكان ياعز :) نشوفك بالجامعة

  • @abdullahmelhim92

    @abdullahmelhim92

    3 жыл бұрын

    ياليل ناشب لي في كل مكان ياعز :) نشوفك بالجامعة

  • @user-ek7cy2lx2t

    @user-ek7cy2lx2t

    3 жыл бұрын

    @@abdullahmelhim92 هههههه

  • @sukanyaurupasula8251
    @sukanyaurupasula82514 жыл бұрын

    Nice video

  • @gunjangupta6618
    @gunjangupta66184 жыл бұрын

    Best ❤❤

  • @onyidoozioma2994
    @onyidoozioma2994 Жыл бұрын

    Finally 🙏🙏

  • @abdullahmagdy19
    @abdullahmagdy192 жыл бұрын

    Nice work Greetings from Egypt, mother of the world 🇪🇬❤️🤍🖤

  • @mx5315
    @mx53154 жыл бұрын

    Thank you for saving me and my cancer biology exam tomorrow

  • @HackDentistry

    @HackDentistry

    4 жыл бұрын

    Great stuff! Our pleasure. Glad to know our videos were helpful.

  • @shutupakshai

    @shutupakshai

    3 жыл бұрын

    is cancer bio a subject

  • @sombuddhabiswas8407
    @sombuddhabiswas84075 жыл бұрын

    amazing content best one

  • @HackDentistry

    @HackDentistry

    5 жыл бұрын

    Thanks very much :)

  • @robertmiller5258

    @robertmiller5258

    4 жыл бұрын

    Has anyone any idea how this might have evolved?

  • @sanadnatekar6329
    @sanadnatekar63292 жыл бұрын

    Good explanation sir👍👍 can you plz do one video on hard tissue mineralisation

  • @aynalsaba7982
    @aynalsaba79823 жыл бұрын

    Thanks alot sir, u cleared my all doubts.