Antibodies | Immunoglobulins Structure & Function | Part 1
#drnajeeb #medicines #pharmacology #antibodies #antibodytest
Antibodies | Immunoglobulins | Structure & Function | Part 1
Like this video? Sign up now on our website at www.DrNajeebLectures.com
to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM KZread). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $45 ONLY!
Sign up now on our website at members.drnajeeblectures.com/...
---------------------------------------------------------------------------------------------------------------------------
Why sign up for premium membership? Here's why!
Membership Features for premium website members.
1. More than 800+ Medical Lectures.
2. Basic Medical Sciences & Clinical Medicine.
3. Mobile-friendly interface with android and iOS apps.
4. English subtitles and new videos every week.
5. Download option for offline video playback.
6. Fanatic customer support and that's 24/7.
7. Fast video playback option to learn faster.
8. Trusted by over 2M+ students in 190 countries.
---------------------------------------------------------------------------------------------------------------------------
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion).
To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few variants, which define the antibody's class or isotype: IgA, IgD, IgE, IgG, or IgM. The constant region at the trunk of the antibody includes sites involved in interactions with other components of the immune system. The class hence determines the function triggered by an antibody after binding to an antigen, in addition to some structural features. Antibodies from different classes also differ in where they are released in the body and at what stage of an immune response.
Together with B and T cells, antibodies are the most important part of the adaptive immune system. They occur in two forms: attached to a B cell or in soluble form in extracellular fluids such as blood plasma. Initially, antibodies are attached to the surface of a B cell - they are then referred to as B-cell receptors (BCR). After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells, which secrete soluble antibodies with the same paratope, or memory B cells, which survive in the body to enable long-lasting immunity to the antigen. Soluble antibodies are released into the blood and tissue fluids, as well as many secretions. Because these fluids were traditionally known as humors, antibody-mediated immunity is sometimes known as, or considered a part of, humoral immunity. The soluble Y-shaped units can occur individually as monomers, or in complexes of two to five units.
Antibodies are glycoproteins belonging to the immunoglobulin superfamily. The terms antibody and immunoglobulin are often used interchangeably, though the term 'antibody' is sometimes reserved for the secreted, soluble form, i.e. excluding B-cell receptors.
(0:00-11:00)
Defining Antibodies/Immunoglobulins.
Plasma Cells; role in producing antibodies;
Antibodies as part of Plasma Proteins; Albumins, Globulins & Fibrinogen.
Globulins; Gamma Globulins are antibodies.
(11:02-29:00)
Basic structure of antibody; Glycoproteins.
Tetrapeptide; 2 Heavy Chains & 2 Light Chains; Y-shaped.
Antigen-Binding Area (ABA); binding specificity of this site & its variable regions;
Variable Domain of the Light & Heavy Chain; Constant Domain"s" of the Light & Heavy Chain.
Antibody Classes: IgG, IgA, IgM, IgE, IgD.
"ME has longer heavy chains".
Review.
---------------------------------------------------------------------------------------------------------------------------
Join this channel to get access to perks:
Sign up now on our website at members.drnajeeblectures.com/...
/ @doctornajeeb
Follow us on Facebook :- / drnajeeb
Follow us on Instagram :- / drnajeeblectures
Пікірлер: 256
Part 2 of Antibodies (Immunoglobulins) Structure and Function will be published within next 48 hours. Stay tuned. ❤️
@mikechaidez3160
3 жыл бұрын
Thanks for the videos!
@hlufe.e
3 жыл бұрын
@@pre-doctorworld7198 pakistan ❤
@mukhtaramin1251
3 жыл бұрын
Thank you sir .the way you deliver the lecture is too impressive .💗💗💗
@khurshidalam1026
3 жыл бұрын
@@pre-doctorworld7198 America..
@pre-doctorworld7198
3 жыл бұрын
@@khurshidalam1026 great ... Thank you 💕
It’s funny how all these years I’ve studying Medicine some people would avoid Dr Najeeb videos because “they take forever” but when I impress the Docs & Professors because I know more they then start to somewhat dislike me, People who watch Dr Najeebs lectures are those who aspire to be the best ❤️❤️❤️❤️❤️ much love from South Africa 🇿🇦 now doing my final year, thank you Doc Najeeb
@DoctorNajeeb
3 жыл бұрын
You are welcome. Best of luck for your future endeavors. ❤️
@gigigigi1508
24 күн бұрын
I've noticed that too when you show you know more either at work or at University everyone will start hate you. If you want to be the best, learn from the best and thank Dr. Najeeb.
When I'm read , I thought what is this, why it is named like this? when dr.najeeb sir teach , I thought how beautifully formed by God, how beautifully discovered by scientists, but most important thing how beautifully taught by dr.najeeb sir .simple , easily understandable, reasonable narration .during watching ur lectures , everytime I thought , he is the messenger from God for medicine profession nd for students.....❤️
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support. :)
@shanthiganthan5691
2 жыл бұрын
Yes u r crt mam.
@drdhirajrajregmi
2 жыл бұрын
Najeeb is a scammer
I lack words to express my gratitudes but for sure you have made me understood this better...much love from🇰🇪🇰🇪🇰🇪🇰🇪🇰🇪
I am from a small village called salboni, Midnapore, in West Bengal. I am studying Zoology honours affiliated to VU. I love your lectures very much. You teach very simply, who doesn't have any idea about biology he also can understand. My previous search on KZread like' anything by anyone'. After your lecture my searches are like 'anything by najeeb sir'. Thank you for your work it really helps us so much..♥️
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support. :) May you be blessed with knowledge, prosperity, love and happiness, always. We wish you success and happiness in every walk of life and good luck in your future endeavors. Regards, Dr. Najeeb Team
Now doing my final year, Dr. Najeeb you’re by far the most the best lecturer 👨🏫 I’ve ever had, THANK YOU
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support.
How could someone be so perfect?? Your lecture made me stay awake for whole night .. because it built my interest in the topic .. first time I took your lecture.. and this is unbelievable i must say❤️❤️❤️
@DoctorNajeeb
2 жыл бұрын
Wonderful! Glad to hear that. Happy learning ❤️❤️
You're lectures are the best! Your teaching methodology, your friendly interaction during the lectures! Just awesome! May Allah bless you !💓
Even though iam a btech graduate and i am seeing your video because you are providing those information in a very interesting way and your lectures consist of those factors which a student doesn't feel any kind of stress or sleep as you are also building curiosity among students which make them listen to you.. respect you sir❤️
@DoctorNajeeb
3 жыл бұрын
Glad to hear that. Stay blessed.
Your lecture explanation are very clear thanks for giving us this opportunity as medical students ,may Allah bless you Dr Najeeb love from Somalia.
Come here with speed of light. Awesome lecture. Just love it.🥰🥰
Intezaar mein bhi itni khushi ho rahi.. Bepanah.. Beandaza.. To wait for your lecture has its own pleasure 😻😻😻
It's really amazing ...May Allah bless you sir
Wow! I think not everyone deserves to be called a teacher. only like you have to be honored so-called "excellent teacher". Thanks. you are explaining everything from the source and the student can go with you easily and easily understand the terms that usually are the nightmare of the students
Ooh thank you for your generosity
No words can define your extra ordinary teaching skills The way you make your students hypnotized by your lectures is breathtaking......Allah bless you always
@DoctorNajeeb
2 жыл бұрын
Thanks a ton for the appreciation. Keep supporting my efforts 💝💝
Thank you very much. Good work
Thank you sir your lecture was awesome. ❤❤❤🙏🙏🙏🙏
YOU ARE THE BEST DR.NAJIB
I was staring at my notes confused. Alhamdulillah I found Ur videos. Thank u so much for making this subject so interesting. May Allah bless you the best.
@DoctorNajeeb
2 жыл бұрын
Glad to hear that❤️
Payi laaagu guru g 🙏🏻🙏🏻🙏🏻🙏🏻...
I am an O Level Student, and before Exams I studied from your lectures and got good marks! Thank You SIR!!
@DoctorNajeeb
3 жыл бұрын
Wow. Great! best of luck.
Thank you sir.. Its very clear💕
You are evergreen sir❤️❤️❤️❤️
Great teaching
U r the best teacher
Awesome sir I am thank ful to you❤️❤️❤️❤️❤️❤️❤️
Dr. Najeeb just knows how to teach. You're the Aristotle of medical students.
@DoctorNajeeb
8 ай бұрын
Thank you for your love and support❤
sir , I am very very proud at you that every country students are getting lot of benefits from INHERENTLY PK-92 DOCTOR,,,I am high school student right now in PAKISTAN,but I have been watching your"s lectures since 2020 because of grandeur explanation.
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support.
Best sr in universe
Great and thanks sir g
Sir u r really a great teacher in world . Your lectures are very useful for all medical students
@DoctorNajeeb
3 жыл бұрын
Thank you.
You are an amazing teacher...I am so grateful to u sir ...ua words nd ua teaching is crystal clear...Ua teaching is mind blowing sirrrrrr.... Good teacher Kind teacher Intelligent teacher Fair teacher Calm teacher😚 Sir keep it up..God bless u sir Lots of love from Kashmir 💓💓💓💓
@DoctorNajeeb
2 жыл бұрын
Thank you for all the love and support dear❤️ Keep supporting ❤️
Sir I m highly impressed by you ....u are an angel for sure....your concepts and the way of explaining is A1.....lots of love and respect 🙏🙏
@DoctorNajeeb
3 жыл бұрын
Glad to know that. Keep sharing your feedback. Thank you for your love and support. :)
Amazing teacher you are
What an amazing lecture on antibody.you r great sir.May Allah Bless you a happy and prosperous life...💖❤️
@DoctorNajeeb
3 жыл бұрын
Glad to know that. Hope this helped you. Keep sharing your feedback.
May u live with happy and prosperous life sir!! ❤️❤️
@DoctorNajeeb
3 жыл бұрын
Thank you for your blessed words.
Great Sir g
i really love u man,,,u r like a dad figure for me ..thank u
Dr najeeb really u are a gift for Pakistan
Please keep teaching us❤️🌙
thank you so much ^-^
thankyou soo much sir 😊 it really helps a lot🤗 You r great sir🤗 Again thankyou soo much lots of love from 🇳🇵❤️
@DoctorNajeeb
3 жыл бұрын
Most welcome 😊
Mashallah very wonderful explanation you make always difficult things into simpler 1 keep it up sir Allah bless you
@DoctorNajeeb
3 жыл бұрын
Thank you for the blessed words.
Good evening dr
The best lecture ever on KZread
@DoctorNajeeb
2 жыл бұрын
Glad you loved it. Stay tuned ❤️
Thank u sir
Sir you are amazing 😊
Sir you are amazing 👏 .. Cristal clear concept 🙏
@DoctorNajeeb
2 жыл бұрын
Thank you for your kind words❤️ Stay blessed❤️
We have quite same topic in 12th.😄
Loved this story of antibodies and antigens , both now appear almost two individuals :)
@DoctorNajeeb
2 жыл бұрын
Glad you enjoyed watching this lecture and got to learn as well 🤗💗
Our teacher 💝💝
Very much appreciate your efforts. Thank you Sir!
@DoctorNajeeb
2 жыл бұрын
Thank you dear. Keep supporting my hard work. ❤️
Nice session
I'm RN but I always enjoy your lecture. You are the best of best. Thank you so much 🙏🙏
@DoctorNajeeb
3 жыл бұрын
That’s so nice of you. Students like you keep me going. More power to you. ❤️🔥
Sir your way of explanation is too good.....A big thanks to you Sir....😊
@DoctorNajeeb
2 жыл бұрын
Glad you loved it. ❤️
Sir your explanation is so better than other and you define all thing clearly .
@DoctorNajeeb
2 жыл бұрын
Made my day! I'm glad that you found my lectures to be more valuable and easy to understand. Stay tuned and stay blessed. ❤️
well sir exellent lecture you dillivered each points with fully explained thank you so much
@DoctorNajeeb
2 жыл бұрын
You are most welcome❤️ Keep supporting ❤️
The legendary teacher of world 🗺
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support.
What a beautifull method sir mashaAllah mashaAllah🤲🤲🤲
@DoctorNajeeb
2 жыл бұрын
Thank you for your love and support ❤️
@sadafsadafsha5965
2 жыл бұрын
@@DoctorNajeeb Sir your convencing power is mashaAllah very high
@sadafsadafsha5965
2 жыл бұрын
@@DoctorNajeeb Thank you soo muchhhh sir for giving me such a great time 🤲🤲🤲 Sir wish you all the best of luck and keep remmber me in your special prayer 🤲🤲🤲
Really Awesome sir... . It's giving a real class room feeling
@DoctorNajeeb
2 жыл бұрын
Glad to hear that. Thank you so much for your love and respect! ❤️
Good evening sir
Sir u are osm Love u SIR
You inspire and give a brief insight Sir. Thanks so much
@DoctorNajeeb
Жыл бұрын
I appreciate that!❤️
Sir, I am always copying ur style of teaching in my class. Salute ❤
@DoctorNajeeb
3 жыл бұрын
Wow. Thank you for your love and support.
Respected team of najeeb sir Your lecture still world best lecture of medical education but now you should record again with New animation, diagram and with new concepts
@DoctorNajeeb
2 жыл бұрын
All because of your love and support dear students! ❤️
Love you sir And long live sir
Wonderful class....May God bless you abundantly....🙏 Thanks for teaching beautifullyy....
@DoctorNajeeb
2 жыл бұрын
Thank you so much for the appreciation! Stay tuned ❤️
Thanks for existing. .... I love u...❤️❤️❤️
@DoctorNajeeb
3 жыл бұрын
Love you too.
It's very helpful to me. Thank you so much 🙏
@DoctorNajeeb
2 жыл бұрын
Glad it was helpful. Stay tuned ❤️
Your lectures are the best 👌 👍 thank your doc
@DoctorNajeeb
Жыл бұрын
Most welcome❤
amazing sir g. keep growing worlds best teacher.
@DoctorNajeeb
2 жыл бұрын
Thanks a lot. Keep supporting ❤️❤️
Great love for Dr. Najeeb May Allah bless you ♥️♥️♥️♥️
@DoctorNajeeb
2 жыл бұрын
You are most welcome. Happy learning ❤️
Thnx
Sir, u are leact and teaching method are very superb ,i blong frm pak ,I m 1st year mbbs student . I have take lots of help frm your leactures, Sir u have miss some leactures of embrylogy which are needed to all students, Ok sir bundle of thanks frm pakistani Students,
@DoctorNajeeb
3 жыл бұрын
Dear, To watch the complete lectures on embryology, Please visit www.drnajeeblectures.com.
@MuhammadIbrahim-wk7ed
3 жыл бұрын
Yes sir video library is full of your leactures problem are solve, Sir all pakistani🇵🇰🇵🇰 🇵🇰people love with U
@shashibalayadav3835
Жыл бұрын
@@MuhammadIbrahim-wk7ed apne sir k course ko 99 rupee m purchase kiya h kya Mujhe kch lectures ni mil rhe the or without purchasing wo library k vedios opn ni ho rhe to mujhe purchase krna h to agr apne kiya ho to aap mujhe purchase krne k process bta do
thank you dr , your explanation so intersting go ahead
@DoctorNajeeb
2 жыл бұрын
You are most welcome! ❤️
You are superb in the world sir...
@DoctorNajeeb
3 жыл бұрын
Thank you.
Awesome Sir Thank you a lot of love from india
@DoctorNajeeb
3 жыл бұрын
Thank you for your love and support. Stay blessed. :)
Thank u so much sir🙏helped me a lot ❤️
@DoctorNajeeb
3 жыл бұрын
Glad to know that. Hope this helped you. Keep sharing your feedback.
Excellent explanation sir.thanq so much
@DoctorNajeeb
2 жыл бұрын
You're most welcome. Stay blessed ❤️
🙏 Good evening Sir awesome presentation
@DoctorNajeeb
3 жыл бұрын
Thank you.
Salute to you Professor Dr Najeeb. I do not understand my college's power point recorded video but your's videos are life saver. It's visual and easy to understand and if we understand then its easy to memorize. Thank you again Sir.
@DoctorNajeeb
9 ай бұрын
You are most welcome
Good morning sir Iam watching this video at midnight 12:12.
god bless you doctor, you inspired me
@DoctorNajeeb
2 ай бұрын
Happy to hear that❤
ALLAH bless u sir ♥️🥰
good teacher thanks
@DoctorNajeeb
8 ай бұрын
You are welcome❤
Your teaching is the best👍💯
@DoctorNajeeb
Ай бұрын
Glad you think so!
Thankyou sir.. Lecture was too good.
@DoctorNajeeb
2 жыл бұрын
Thank you for your appreciation! ❤️
O m g... U r genius 👍🏻👍🏻👍🏻👍🏻👍🏻 yr explanation is veryyyyyy veryyyyy clear👍🏻👍🏻👍🏻👍🏻👍🏻 ❤️❤️❤️❤️❤️ I'm very much interested your lacture... 🎈🎈🎈
@DoctorNajeeb
2 жыл бұрын
Thank you so much ❤️ Keep supporting❤️
Sir you are the bestest teacher
@DoctorNajeeb
3 жыл бұрын
Thanks a lot, it makes my day to hear that. Happy learning.
Thank u sir 🙏
@DoctorNajeeb
2 жыл бұрын
Most welcome💓
Sir, you are amazing ❣️❣️
@DoctorNajeeb
Жыл бұрын
Thank you❣️ Keep supporting ❣️
Sir u are the best best best best...........................❤❤❤❤💖💖
@DoctorNajeeb
3 жыл бұрын
Thanks alot.
Making very very easy, u present this lecture. Thqnks a lot,sir
@DoctorNajeeb
3 жыл бұрын
Glad to know that. Hope this helped you. Keep sharing your feedback.
@r-48tanusreesaha84
3 жыл бұрын
@@DoctorNajeeb Thank you so much sir for ur reply♥️
Thank you so much sir 🥰
@DoctorNajeeb
3 жыл бұрын
You're welcome stay blessed. :)
Thanks for all
@DoctorNajeeb
3 ай бұрын
You are welcome ♥
May you live long my great sir Becuse i follow your methodology
@DoctorNajeeb
2 жыл бұрын
Thank you for your kind words❤️
@sadafsadafsha5965
2 жыл бұрын
@@DoctorNajeeb 🤲🤲🤲🤲🤲🤲🤲🤲🤲🤲🤲i have no word to explain your methodology very very best best mashaAllah
you are great sorry to say some are disliking
Mashallah awesome 👍👍 I love ur teaching method sir
@DoctorNajeeb
3 жыл бұрын
Thank you for your love.
@azizrocky2335
3 жыл бұрын
@@DoctorNajeeb always welcome my ideal sir
Immune System_1 Antibodies(1) 24-06-2021 Morning Thanks,Sir!
@DoctorNajeeb
3 жыл бұрын
You're welcome stay blessed. :)