Anti-Psychotics Explained and the History of Psychopharmacology (History of Psychiatric Drugs).

Anti-psychotics explained, by reviewing the history of psychopharmacology, and the history of psychiatric drugs.
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Sources:
Ramachandraiah CT, Subramaniam N, Tancer M. The story of antipsychotics: Past and present. Indian J Psychiatry. 2009;51(4):324-326. doi:10.4103/0019-5545.58304
Carpenter, W., Davis, J. Another view of the history of antipsychotic drug discovery and development. Mol Psychiatry 17, 1168-1173 (2012). doi.org/10.1038/mp.2012.121
The video delves into the history and development of antipsychotic medications, focusing on the differences between typical and atypical antipsychotics. It begins by exploring the psychoanalytic perspective on mental health disorders prevalent until the 1950s, highlighting the lack of effective treatments. This changed with the discovery of chlorpromazine (Thorazine) in the 1950s, marking a paradigm shift towards biological approaches to treating mental illness. Chlorpromazine's efficacy in treating schizophrenia led to a surge in its usage and the emergence of psychopharmacology as a field. However, typical antipsychotics like Thorazine had significant side effects, including extrapyramidal symptoms (EPS). The introduction of haloperidol (Haldol) in 1958 offered a more potent alternative with fewer side effects. The classification of antipsychotics into high, middle, and low potency helped guide treatment choices based on their receptor affinities. The video also touches on the serendipitous discoveries of antidepressants like MAOIs and TCAs, shedding light on the evolution of psychiatric medication. The term "atypical antipsychotics" emerged with the discovery of clozapine, marking a new generation of medications. Overall, the video provides a comprehensive overview of the development of antipsychotics, from their serendipitous discoveries to their classification and evolving understanding of mental illness.
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#psychopharmacology #pharmacology #pmhnp #psychnp
00:00 Farm-House Intro
00:31 Intro
00:50 Can't Not Talk About Freud
01:34 Pre-1950 Psych Treatment
02:08 Thorazine
02:47 Mood Stabilizer Tangent
05:25 Dopaminergic Pathways
07:55 Haldol
08:51 Potent Potables
10:22 Anti-Depressant Tangent

Пікірлер: 34

  • @tristanwegner
    @tristanwegner2 жыл бұрын

    The history was really interesting. Looking forward to the next part.

  • @Dudemon-1
    @Dudemon-12 жыл бұрын

    How does someone find a clinician who uses such thoughtful analysis, rather than just throwing random medications at a problem?

  • @PsychoFarm

    @PsychoFarm

    2 жыл бұрын

    Someone, quick, medicate this guy^

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @sugarhana
    @sugarhana2 жыл бұрын

    I'm a PGY2 psych resident and thinking about/actually studying for boards makes me want to fall asleep. These videos are so well made and getting me interested in psychopharm. Thank you!!!

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @Royalewithcheese3000
    @Royalewithcheese30002 жыл бұрын

    Another cracking video, you deserve many more views!

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @seancady4570
    @seancady45708 ай бұрын

    This filled in so many gaps I had with antipsychotics. Appreciate the info brother, you deserve FAR more views than you have currently.

  • @Ruturaj240
    @Ruturaj2402 жыл бұрын

    This channel is so good. The videos are amazing!

  • @Eve0127
    @Eve01272 жыл бұрын

    I am literally obsessed with these videos. I just subscribed. You're amazing.

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @ddd778
    @ddd7782 жыл бұрын

    Amazing, thank you!

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @naftalibendavid
    @naftalibendavid7 ай бұрын

    Nice work.

  • @paulflur4519
    @paulflur45193 ай бұрын

    You’re very informed and have nice editing. I subscribed. The whole world is a psych ward.

  • @LeonAruba
    @LeonAruba13 күн бұрын

    thanx a lot for everything you have uploaded.

  • @PsychoFarm

    @PsychoFarm

    12 күн бұрын

    You are welcome!

  • @summer7529
    @summer75292 жыл бұрын

    Please do a video on ziprasidone, it's side effect profile is so much better than other APs. Thank you so much your videos are really helpful in my Psych rotation. Helps understand the history and the mechanism. Thanks for making these

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

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  • @aniki1934

    @aniki1934

    Жыл бұрын

    The withdrawal can be brutal though tbf

  • @summer7529

    @summer7529

    Жыл бұрын

    @Aniki what do you mean ? Can you please elaborate.. Why would the medicine be withdrawn if it's working fine?

  • @Plataani

    @Plataani

    10 ай бұрын

    ​@@summer7529well... Schizophrenics or any psychotic patients aren't the most treatment compliant patients out there - psychotic strike-throughs might make some just quit meds.

  • @unknown-10k
    @unknown-10k2 жыл бұрын

    I have a question sir is the nature vs nurture debate over or not yet ??

  • @PsychoFarm

    @PsychoFarm

    2 жыл бұрын

    I will probably circle back, but it won't be for quite some time!

  • @wobina
    @wobina Жыл бұрын

    To me the "really scary one" is dystonia. Having a dystonic reaction and especially not being informed enough to know what is happening is the worst....... Tardive dyskinesia is mild in comparison....... Sucks it's permanent but yeah

  • @polarbear1954
    @polarbear19542 жыл бұрын

    Sooo good and easy to follow. The intro is so good 😂🥲

  • @milatripzonInstagram

    @milatripzonInstagram

    Жыл бұрын

    Check out👆👆I got the best (psych), mushroom,chocolate bar, SSRIs,SNRIs,TCAs, LSD,they are the best and free shipping......

  • @Lpm100
    @Lpm100 Жыл бұрын

    This channel just kills me. I've listened to the few videos, and a couple of them did not even finish. Also, he used a sample of a Madonna song in one, and, I believe, the theme song from the TV show "Full House" in 2 other

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