Easily Learn SGA Antipsychotic Receptors (Learn Anti-Psychotics and Anti-Psychotic Differences)"
Easily learn anti-psychotics through their differences including their mechanisms of action, how they interact with anti-psychotic receptors, and the nuanced anti-psychotic medication differences that influence treatment choices.
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The video provides an intuitive way to easily learn anti-psychotics and memorize the similarities and differences among atypical antipsychotics. It categorizes them into subclasses: the "pines" (olanzapine, quetiapine, clozapine), the "dones" (paliperidone, risperidone, ziprasidone, lurasidone), and the "pips and a rip" (aripiprazole, brexpiprazole, cariprazine).
The video introduces the concept of receptor "fountains," which represent the backbone of receptors that each subclass binds to. This helps explain the similarities in side effects within each subclass. For instance, the pines tend to cause more sedation and weight gain due to their affinity for histamine (H1) and muscarinic (M1) receptors.
By understanding these receptor backbones, one can intuit the side effects of a drug based on its subclass, rather than memorizing individual side effects. The video also highlights subtle differences within subclasses, such as olanzapine lacking the alpha-1 receptor, resulting in less orthostatic hypotension compared to quetiapine and clozapine.
Additionally, the video points out patterns within subclasses, like quetiapine and olanzapine being effective in treatment-resistant depression, clozapine and olanzapine causing the most weight gain, and ziprasidone and lurasidone requiring food for better bioavailability.
Overall, the video presents a novel and intuitive approach to comprehending the receptor profiles and side effects of atypical antipsychotics by organizing them into subclasses with shared anti-psychotic receptors backbones, making it easier to grasp the anti-psychotic medication differences among these drugs.
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#psychopharmacology #psychnp #pmhnp
0:00 And everything is going to the beat
0:11 Intro
0:27 SGAs
1:02 The Pines, The Dones, 2 Pips & A Rip
2:20 Chemistry is just shapes!
2:29 Receptor Profile
3:27 More fountains!
4:53 Charts suck
7:33 Little Patterns
8:35 End Screen
Пікірлер: 20
This is hopefully the new meta of educational psych content. So so good.
Wildly excellent video. I never thought to sub-classify the antipsychotics based on their chemical structure. Your explanation of why each sub-group causes different side effects was amazing. Thank you so much for this video
The pines, the dones, 2 pips and a rip!!
Great content - appreciate the educational technique!
I hope your doctorate is eventually worth it. You're doing a lot of good work.
Excellent presentation! Thank you for sharing.
very useful video - thank you!
Thanks so much dude. Very understandable.
I'm on abilify maintena. Thanks for the great explanation of the antipsychotic class.
You got the chemical structures of lurasidone and ziprasidone mixed up in your visual aid.
My memory sucks for everything except for receptor affinities for some reason. Like I can see a chart of receptor affinities for Doxepin or something for 5 minutes and remember it, but never remember what I ate yesterday or anything that a normal person would.
The fountains are great!
@PsychoFarm
Жыл бұрын
For those in the know, the fountains are filled with rum
I feel like I've watched this video a few times now. Are these just reuploads and if so, will you be making new content as well? Looking forward to it
@PsychoFarm
2 жыл бұрын
New content is being made! This is re-created older content with updated audio/smoother graphics.
Great overview, thanks! A side note: I think you have the structure of brexpiprazole wrong and thus also the highlighted structures, mate. The structure in common is the right side of the molecule :)
@PsychoFarm
9 күн бұрын
Impressive catch! Thanks
No fucking way, this is so good. THANK YOU!!!
Question on the done subclass would this be the same concept for things like trazDONE and for the pines with benotroPINE?