ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret
In this TachyTutorial, we explore the basic principles of interpreting Liver Function Tests. We explain what the enzymes ALT, AST, ALP, GGT and what the clinical significance is if their levels are raised. We also explain some special relationships between these enzymes!
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#LiverFunctionTests #ALT #HowToInterpret
Пікірлер: 302
For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.
@Neenah44
Жыл бұрын
Did you have any other symptoms?
@MrSmith-yr9vk
Жыл бұрын
@@Neenah44 For RCC, not a single one. If I would have just done nothing, I probably would be Stage 3 or 4 by now. My Urologist said that if the tumors would have been reversed, the Ultrasound on my liver would not have seen the tumors and I would not have made 60. I was 46 when we found RCC Stage 2.
@Neenah44
Жыл бұрын
@@MrSmith-yr9vk Thank you for answering me I appreciate it very much. I’m happy that you were persistent in finding out why your numbers were growing higher. You literally saved your life. A great lesson on advocating for ourselves! Thanks again. Happy new year! 😊
@MrSmith-yr9vk
Жыл бұрын
@@Neenah44 Happy New Year to you and you are very welcome. RCC was not the answer I wanted to hear, but it was the answer to my problem so far.
@ramathakur3667
Жыл бұрын
@@MrSmith-yr9vk bro.... i have ....258.0 - AST,471.9 -ALT,221.9-GGTP,447.00 - ALP ............ i was used to be proper in shape with 83 kg BW...now it turned into 73 in just 2 weeks.... i used to hit gym.... no alcohol ..even not fast food intake.... nd now i fukd upp
All I can say is WOW! I could not understand these enzymes any better. I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results. Im officially your subscriber from now.
@TachyTutorials
2 жыл бұрын
Thank you so much for your great feedback! Very useful! Glad you enjoyed and welcome to the channel!
Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!
@TachyTutorials
2 жыл бұрын
Thank you for watching!
@HepatitisBChannelHepatitisB
11 ай бұрын
Seems way too dramatic bearing in mind everyone often has raised alt.... with every course of pain killers, pub visit, protein shakes use, junk food lifestyle and many passing infections. None of these raises represent liver damage... so maybe remove the damage and put back the function where it belongs
The best video out there on LFTs!! Thank you so much!
@TachyTutorials
3 жыл бұрын
Thank You!
@rubidiumandi2334
3 жыл бұрын
True
@andrewadali6121
2 жыл бұрын
@@TachyTutorials ,
@ZahidHussain-ht4tw
2 жыл бұрын
Right 👍👍
This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well
thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..
That truly was the best and most informative, easy to understand explanation ever. Thank you!
@TachyTutorials
2 жыл бұрын
Thank you for watching! 🙂
No one can do better explanation than this. i really find value
@TachyTutorials
4 ай бұрын
Thank you!
Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.
@TachyTutorials
2 жыл бұрын
Thank you for your support!
Thank you so much.... Best I have ever seen.
@TachyTutorials
Жыл бұрын
Wow! Thanks so much 🙂
Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.
@jjohnson9822
2 жыл бұрын
how u going now bro?
@stanleycates1972
2 жыл бұрын
@@jjohnson9822 good, except being 85. The body is worn out from overuse :)
@ragavansrinivasan1961
2 жыл бұрын
Good evening sir, were is treatment autoimmune hepatitis primary bailary colanjaitis.
@damariskendrick2591
Жыл бұрын
Hello Mr Stanley Cates. Did you have to take prednisone or azathioprine? Asking because I had the same diagnosis and my gallbladder removed.
This is the best explanation ever…..
Excellent presentation to Doctors and Patients
Excellent presentation! Thank you very much!
@TachyTutorials
Жыл бұрын
Appreciate the comments. Thank you very much
Fantastic video. Thank you
Thank you... you saved many hours of my study time 🥰❤️
@TachyTutorials
Жыл бұрын
Glad you found it useful 😊
Beautifully done, sir!
Thank you so much for the clear explanation!
@TachyTutorials
Жыл бұрын
Glad you found it useful 😊
Excellent explanation. Thank you.
@TachyTutorials
3 жыл бұрын
Thank you for watching!!!
Wonderful explanation. Keep sharing more
@TachyTutorials
3 жыл бұрын
Thank you for your support!
Very helpful video. Thanks a lot. 👍
Genius. amazing explanations
@TachyTutorials
3 жыл бұрын
Thank You!
Well explained to my understanding. Thank you very much
very clear explanation, thank you very much
Thank you so much for this very informative video.
@TachyTutorials
2 жыл бұрын
Thank you for watching 🙂
It was more than awesome! Keep up!
@TachyTutorials
2 жыл бұрын
Thank you! Glad you enjoyed 🙂
Awesome video! New sub man
@TachyTutorials
3 жыл бұрын
Thank you so much!
Wow thank u for this eloquency 👏🏻👏🏻👏🏻
@TachyTutorials
2 жыл бұрын
Thanks for watching 🙂
Good explanation, animations superb.
@TachyTutorials
3 жыл бұрын
Thank You!
U absolute gem Thankyou
@TachyTutorials
2 жыл бұрын
Thank you so much! 🙂🙂🙂
Thank you thank you thank you! ❤️
@TachyTutorials
2 жыл бұрын
Thanks for watching!
Amazing explanation!
@TachyTutorials
Жыл бұрын
🙂🙂🙂
great explanation, thank you very much
@TachyTutorials
Жыл бұрын
Your welcome 🤗
thank you. really really useful.
@TachyTutorials
2 жыл бұрын
Thank you for watching 😀
Wow , Awesome thank you Doctor
Good explanation, thank you
@TachyTutorials
3 жыл бұрын
Thank You!
Excellent explanation❤
ty 4 the awesome video
@TachyTutorials
2 жыл бұрын
Thanks for watching 🙂
Great vid Thanks!
@TachyTutorials
Жыл бұрын
Thanks for watching 🙂
In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis
Thank you for this video.. God bless 🙏
@TachyTutorials
Жыл бұрын
Thanks for watching 🙂
Very good explanation...❤
I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.
Thank you, that was very easy to absorb 🙂
@TachyTutorials
8 ай бұрын
Thanks for watching 😀
Thanks great summary.
@TachyTutorials
Жыл бұрын
🙂🙂🙂
This is the amazing video 🎉
@TachyTutorials
Жыл бұрын
Thanks 😀
Very nice explained
Mine was due to alpha1antitrypsin deficiency! I think everyone with the high levels should be checked for this today! It’s not an expensive test and needs an early diagnosis when possible🙏
Great lecture.
@TachyTutorials
Жыл бұрын
🙂
Excellent explanation.
@TachyTutorials
Жыл бұрын
😀😀😀
Good job
Got ur subscription deserves it
excellant teaching
@TachyTutorials
Жыл бұрын
🙂
Thank you!
@TachyTutorials
Жыл бұрын
Your welcome 🙂
Thanks. good and perfect
@TachyTutorials
2 жыл бұрын
Thank you for watching!
Just amazing
@TachyTutorials
2 жыл бұрын
Thank you! Glad you enjoyed 🙂
Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.
@user-ne8vl2uh8g
3 ай бұрын
What if you don't drink and no it's not
very helpful thanks
@TachyTutorials
2 жыл бұрын
Thank for watching! 🙂
Thank you so so much 😍😍
@TachyTutorials
2 жыл бұрын
Thanks for watching 🙂
Brilliant
Thumbs up👍👍👍
@TachyTutorials
2 жыл бұрын
Thank you!
Really superb
@TachyTutorials
2 жыл бұрын
Thank you so much! 🙂
Very informative
@TachyTutorials
2 жыл бұрын
Thank you!
Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?
@andrewlobuznov
2 жыл бұрын
Alcoholism 🔥
@brax5715
2 жыл бұрын
@@andrewlobuznov what if you do not drink?
@brothertn708
Жыл бұрын
How’s your liver doing now?
@mudassarjabeen7548
Жыл бұрын
Yes ,u also want to ask , same reports,,can't interpret
@mudassarjabeen7548
Жыл бұрын
@DL 0001
What could a high AST:ALT ratio (>2) with low to normal GGT suggest?
Well explained
@TachyTutorials
2 жыл бұрын
Thank you! 🙂
Very clear video. What is the potential diagnosis please if there is an isolated abnormal ALT of 127? I am talking about a young nondrinker who does not so suffer from haemochromatosis. I mention haemochromatosis because his serum ferritin is also high, as is his creatinine. No viral hepatitis detected.
@12mach
Жыл бұрын
Tell him cut pork out diet its high polysatured fats are higher than alcohol
Best video
@TachyTutorials
2 жыл бұрын
Thank you for watching 🙂
Thank you so much for sharing this info! I just received my blood test result and have high ALP. The rest are alright so now I can decide to do a bone scan first just to make sure everything is ok. Cheers!
@kittyarcade2296
2 жыл бұрын
Mine started with ALP and then the rest started to elevate in a cyclical pattern. Just be sure to follow up every few weeks, months, whatever your doctor recommends.
What does it mean if there is no liver damage? Does it mean that it is functioning well?
Thank yo so much
Concise and to the point. So helpful! Thank you so much!
@TachyTutorials
3 жыл бұрын
Glad you enjoyed!
Could raised ALT and AST be due to beta blockers and/or anti-coagulants?
what about NAFLÐ (non alcool fatty liver disease)?
Can anyone plzz explain me the difference between liver infection and liver damage???
You got a subscriber.
@TachyTutorials
2 жыл бұрын
Thank you and welcome to the channel! 🙂
@densilcardna
2 жыл бұрын
@@TachyTutorials Thank you.
So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?
Great analysis but i suggest you to use better microphone for sound quality
My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.
@Jeswin_Jose
Жыл бұрын
Did you get the answer for your concern?..I also want to know whether the ratio is important or the values of AST and ALT are important.
Wishing you had included a low ALP result. Otherwise, great information.
Tacky tutorials Can the DTaP shot raise AST if given directly before blood work?
my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain? My AST and ALT were normal
What about alkaline phosphatase at first test 182 now 211, 5 weeks later and alt at 48? Thoughts? Everything else seems to be good
Upon getting my Bloom simple tests results.....de hace discovered i am experiencing "LowLevels of GamaGlutamylTransferase" I am uncertain what that implies....i do know i am experiencing VeryLowEnergyLevels????
My ast level is 36 and alt is 18 , but ast alt ratio is 2 , is there any problem?
i am hep b patient what test results interpret that i am in danger or out of danger?
Thanks sir 👍👍
@TachyTutorials
2 жыл бұрын
Thank you for watching! 🙂
Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation
wow. 👌
@TachyTutorials
25 күн бұрын
Thanks ❤️
Hello, my GGT numbers are coming out to 111 other than that everything else is good. I have over a year and a half with out drinking alcohol just recently i had 1 drink thats it. What are the factors that could be causing my numbers to continue to increase? And is it reversable? If so how can I drop the numbers?
@pavanpabbireddypavanpabbir1897
2 жыл бұрын
My ggt level went to 166 and i dont know what to do? Any suggestuons ?
@timh-c7186
Жыл бұрын
@@pavanpabbireddypavanpabbir1897 ...suggest low carb/keto diet
@timh-c7186
Жыл бұрын
sugar causes high GGT, as I understand it
ihave an Isolated high GGT all others are normal, and im not an alcohol drinker, What could this isolated ggt mean?
@shoot4thstars
Жыл бұрын
I have the same, and it accompanies hepatobiliary problems. I have read, it can be indicative of inflammation of the bile ducts.
Alt 40. AST 30. Alp 47. Ggt 85u/l. Have not drank alcohol for 5 years. What’s up with ggt being 20 points out of range?
What if my ast is slightly elevated am I okay ??
Normal AST &ALT but alightly high GGT ( results 43 &51) can chemo do this?
Ast Alt ratio is 1.35 normal or not.
I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?
ALt 180 Ast 68 What to treat for it??? Plz give me advice and tell me is it normal
My ast 52.8 and alt 86.1....sap 103 pl suggest it's ok
What if the ALP is LOW ?
I had fever vomiting for a week then had my ultrasound and blood work done in the 11th day of my first symptoms My blood test showed multiple times higher liver enzymes alt was the highest tho. I started developing jaundice at the 10th day. I had my ct and another ultrasound by the end of the second week but it was all good except for a few lymphnodes enlarged next to the gallbladder. On the 19th day i had a new blood work and it showes all enzymes decreased drastically and it is not too far from highs normal levels. Thats being said bilirubin kept increasing and hit 125 umol/l while it was 77 in the first blood work. I am feeling much better but still cant eat normally because i get uncomfortable feelings in my guts Any ideas?
@user-zl3xs1cf8x
Жыл бұрын
It sounds like a bile duct blockage perhaps? Blocked by sludge. The bible ducts release bile that aids in helping to break down the food we eat so the stomach can digest it. If there's a slow down in bile production, then it effects how we digest food and can cause stomach pain, but if it's mainly the Alt that's elevated, it can often point to liver and the Ast can be liver but very high can point to the billery system. I'm not a doctor, but since I have chronic liver disease, I would naturally do the research. Your P.C.P should get you set up with a G.I./ heptology Doctor. It's not like you will get any answers on these sites from an actual Dr. As they hate to give info without running their exams on the patient first, and perhaps to even get in trouble hand out info. But again you should see a specialist being a G.I. / heptology, I would!! Good luck.🙏