A 3D animation of mismatch repair in E. coli

Ғылым және технология

Made using Blender 2.75 as part of my third year Practical Project (BSc Medical Biochemistry).
March 2016

Пікірлер: 142

  • @Gamelover882
    @Gamelover882 Жыл бұрын

    My professor recommended this video and I see why. It's quick, in plain English, well animated and accurate without over complicating things. Thank you!

  • @DendyJungle
    @DendyJungle7 жыл бұрын

    dont know why you are giving this away for free but i am glad you are. Usually have to pay for really good educational videos

  • @faig4289

    @faig4289

    5 жыл бұрын

    Shut up

  • @ej_stories

    @ej_stories

    3 жыл бұрын

    @@faig4289 😂😂😂

  • @factualbiology7769

    @factualbiology7769

    2 жыл бұрын

    kzread.info/dash/bejne/m4NnlNqDdpTJhM4.html

  • @samarrowsmith1396
    @samarrowsmith13966 жыл бұрын

    If anyone enjoyed this video and would like to see another of the sort, please suggest your ideas! I'm looking for suggestions for the next topic to animate!

  • @axellir

    @axellir

    6 жыл бұрын

    The video really helped me to visualize the process! Thanks! How about an animation about homologous recombination?

  • @holden2966

    @holden2966

    5 жыл бұрын

    DNA techniques ?

  • @blandon93

    @blandon93

    5 жыл бұрын

    How dna polymerase select nucleotudes in replication. Does it take nucleotides freely or they stick?

  • @singhmilandip

    @singhmilandip

    4 жыл бұрын

    I would like to see SOS response...

  • @srikantadash4603

    @srikantadash4603

    3 жыл бұрын

    Transcription Translation post translational modification

  • @hoshi1599
    @hoshi15992 жыл бұрын

    Beautiful. I didn't realise there was going to be a bend with mutH while studying. This clears up so much .

  • @peednas711
    @peednas71118 күн бұрын

    Bro I have a professor in molecular cell biology. He's been a professor there for 10-15 years. And still, you were able to explain this mechanism better than him. Good job to you. This is your calling

  • @truth2power528
    @truth2power5286 жыл бұрын

    Great video Sam. This helps tremendously in visualizing the process and makes it easier to understand.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @trudyandgeorge
    @trudyandgeorge Жыл бұрын

    Went looking for explanations on cyclical redundancy checks and wound up here. So Mother Nature did it first! Bravo 👏

  • @johnhenry4389
    @johnhenry43898 жыл бұрын

    That was one of the best videos of DNA-enzyme interaction I've seen.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @parth2615

    @parth2615

    3 жыл бұрын

    @@samarrowsmith1396 I was studying for my molecular genetics course, I couldn't visualize the mismatch repair system so I searched "DNA mismatch repair" on youtube. This was the second recommendation. PS. It's a great video. I recently learned the basics of blender, I will also try making such nice little animations just for fun. Hope this was helpful.

  • @factualbiology7769

    @factualbiology7769

    2 жыл бұрын

    kzread.info/dash/bejne/m4NnlNqDdpTJhM4.html

  • @Ragunath21

    @Ragunath21

    2 ай бұрын

    ​@@parth2615 now it's first in recommendation

  • @holden2966
    @holden29665 жыл бұрын

    Wow! This great! Made perfect sense in just 3 minutes. Great animation! Keep it up Sam

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @holden2966

    @holden2966

    3 жыл бұрын

    @@samarrowsmith1396 I just searched it up

  • @carlosalbertolararojas3610
    @carlosalbertolararojas36103 жыл бұрын

    Thank you for this video I was trying to study methods of DNA respiration and I could not visualize this in my mind , you made it a lot easier for me many thanks.

  • @hafsaamzim1901
    @hafsaamzim19012 жыл бұрын

    It’s amazing and very clear. Thank you a lot.

  • @sliceofnoob2885
    @sliceofnoob28853 жыл бұрын

    Thanks the best vid I've found on mismatch repair....a real life saver

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @Lillith9008
    @Lillith90083 жыл бұрын

    This is one of the most aesthetically narrated biology videos I have seen. Thank you :D

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @factualbiology7769

    @factualbiology7769

    2 жыл бұрын

    kzread.info/dash/bejne/m4NnlNqDdpTJhM4.html

  • @pulgimole5
    @pulgimole58 жыл бұрын

    Very helpful! thank you

  • @adityakale6064
    @adityakale60643 ай бұрын

    It was so simple to understand and you saved me for my exams

  • @nikitamaurya6644
    @nikitamaurya66446 жыл бұрын

    Thank you so much,it helped me a lot.

  • @noorulhassankhan
    @noorulhassankhan3 жыл бұрын

    Wonderful video, thank you so much!

  • @theeducationtree8272
    @theeducationtree82725 жыл бұрын

    AMAZING!! THANK YOU.

  • @a.i892
    @a.i8923 жыл бұрын

    One of the best educational videos i've ever seen

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @shivamverma2754
    @shivamverma27542 жыл бұрын

    wow so much wow ... great job Sam

  • @litchfirmian7562
    @litchfirmian75622 жыл бұрын

    This is really helpful, thank you, sir.

  • @satabdideka8832
    @satabdideka8832Ай бұрын

    Ahh, you made it so easy! Thanks a lot

  • @maryamsediqi3726
    @maryamsediqi3726 Жыл бұрын

    Awesome, thank you so much

  • @DL551997
    @DL5519977 жыл бұрын

    extremely helpful. thank you very much!

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @musicspeaks0101
    @musicspeaks01016 жыл бұрын

    thank you so much!!!

  • @harvey2733
    @harvey27333 жыл бұрын

    Such an amazing presentation. Loved it.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @niharikagovindjha8919
    @niharikagovindjha89196 жыл бұрын

    it's really good but a bit more clarity about methylation and also references to RecJ and endonuclease VII would have been great

  • @wealllovelina
    @wealllovelina3 жыл бұрын

    awesome animation! thanks!

  • @Mk-hc9jm
    @Mk-hc9jm3 жыл бұрын

    Legend, thank you so much

  • @hayilee9601
    @hayilee96012 жыл бұрын

    you just saved me! thank you so much :)

  • @ayeshaqamar5972
    @ayeshaqamar59724 жыл бұрын

    Thank you so much for the video

  • @nitukharsel3625
    @nitukharsel3625 Жыл бұрын

    A well animated vdo 😊. I liked it very much .please animate mor topics of Molecular biology😢

  • @feliscatus4921
    @feliscatus49212 жыл бұрын

    this is an informative and useful video!

  • @lisarichards3217
    @lisarichards32177 жыл бұрын

    More science videos! This is well done.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @twisampatidas9965
    @twisampatidas99653 ай бұрын

    Awesome brother

  • @ubaldogennaromastrominico786
    @ubaldogennaromastrominico7862 жыл бұрын

    Great job!

  • @wasifullahdawar6962
    @wasifullahdawar69623 жыл бұрын

    Thank you

  • @superiorslush5147
    @superiorslush5147Ай бұрын

    every good 3d biochemistry animation has a british accent

  • @blancaparraga3006
    @blancaparraga30063 жыл бұрын

    Thank you so much

  • @aisheebhattacharya4228
    @aisheebhattacharya42285 жыл бұрын

    Wht abt uvrD helicase?

  • @kalpanamurmu3776
    @kalpanamurmu37765 жыл бұрын

    Thanks you sir .

  • @arvindshankar7679
    @arvindshankar76795 жыл бұрын

    Good work fam, this is helpful.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @atanasatanasov9036
    @atanasatanasov90367 жыл бұрын

    Awesome! Thanks

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @saja4887
    @saja48874 жыл бұрын

    Thanks a lot :)

  • @lapetiteloutre9345
    @lapetiteloutre93455 жыл бұрын

    Great video, thanks a lot :)

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @corvette724
    @corvette7244 жыл бұрын

    well done Blender job

  • @reviewsbymithy8532
    @reviewsbymithy85323 жыл бұрын

    Question please Why Dna is looped out in search of nearest d(GATC) methylation site?

  • @malekmohamad4815
    @malekmohamad48152 жыл бұрын

    that was epic..my regards from syria

  • @ryanisber2353
    @ryanisber23532 жыл бұрын

    So good

  • @Ssalma6338
    @Ssalma63389 ай бұрын

    About the DNA polymerase , is it polymerase III which is responsible for the resynthesise of the new strand or the Polymerse I ? I get confused

  • @shafiamobasheri830
    @shafiamobasheri8302 жыл бұрын

    The best ever

  • @user-hq8mx7mn3u
    @user-hq8mx7mn3u6 жыл бұрын

    Infinitely helpful

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @elnazzeinali3240
    @elnazzeinali3240 Жыл бұрын

    Thats good tnx

  • @zuhaltatar935
    @zuhaltatar9355 жыл бұрын

    İts very helpfull! Thank you so much :)

  • @SURESHKUMAR-gt7eo

    @SURESHKUMAR-gt7eo

    4 жыл бұрын

    Hello

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @matthewgrammatico8434
    @matthewgrammatico84347 жыл бұрын

    thanks mate. great video!

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @matthewgrammatico8434

    @matthewgrammatico8434

    3 жыл бұрын

    I was doing a genetics module at the university of Nottingham and just searched mismatch repair on KZread. It's a great video because of the visual aspect.

  • @richachawla7931
    @richachawla79317 жыл бұрын

    Amazing

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @ej_stories
    @ej_stories3 жыл бұрын

    👌👌👌

  • @katarinala
    @katarinala7 жыл бұрын

    THANK YOU, it was so confusing in my book!

  • @asifhamid9676
    @asifhamid96766 жыл бұрын

    Superb.....

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @AlessandroDonaggio
    @AlessandroDonaggio3 жыл бұрын

    hope you got a first for this!

  • @7mikepd
    @7mikepd7 жыл бұрын

    i think it's dna polymerase I that fills in the nucleotides before ligase fills in the nick.

  • @camelliaxie9381

    @camelliaxie9381

    7 жыл бұрын

    Pol I is for proof reading and Nick translation (replacing RNA primers between Okazaki fragments). Pol III is for elongation, so the video is correct.

  • @zsusanner

    @zsusanner

    6 жыл бұрын

    The video is correct. It is DNA polymerase III that fills the gap

  • @user-de3qh4os7s
    @user-de3qh4os7s7 жыл бұрын

    thank you...... please how can download this video

  • @Ahnzhie

    @Ahnzhie

    7 жыл бұрын

    1. Go to www.keepvid.site/ 2. Copy the link of this video and paste it on keepvid site 3. Click download and you can find more options down :)

  • @zaynas2100
    @zaynas21007 жыл бұрын

    It's a very good video thanks

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @mcpba3857
    @mcpba38575 жыл бұрын

    1:15

  • @maheenejaz360
    @maheenejaz3605 жыл бұрын

    Kindly tell mismatch repair of e. Coli and eukaryotes differs? Pls answer as soon as possible.

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Hi Maheen, I realise this is a VERY late reply on my part so I can only apologise. I imagine my hesitation to answer this question is because I don't fully know the answer myself. There are analogues of the mismatch proteins across life, but the difficulty comes of looking at things within the chromatin environment. Making an accurate animation of the movement of histones and unzipping the DNA strands that have been exposed would be a comparative nightmare (for me anyway, there are probably skilled animators who could try making a representation of this). The wikipedia article for mismatch repair has a basic outline of the analogues: en.wikipedia.org/wiki/DNA_mismatch_repair

  • @abhiriseagain9303
    @abhiriseagain93034 жыл бұрын

    awesome vid thank youu

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @abhiriseagain9303

    @abhiriseagain9303

    3 жыл бұрын

    @@samarrowsmith1396 Hey thank you so much for your video. I searched for DNA repair and your video came up in search results..I watched many , this was the best one. For me this video was very beneficial in understanding the topic easily. And the animation was amazing, gave a clear picture. These are the topics which confuses some, so people tend to search for this kind of videos maybe thats why and you did a great job with the video.

  • @anilk1241
    @anilk12417 жыл бұрын

    great video !! - a medical student

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @priyasultania8943
    @priyasultania89435 ай бұрын

    Dam good

  • @agri_lover_boy1292
    @agri_lover_boy12923 жыл бұрын

    Please apki volume high kordo

  • @stephenhawking9155
    @stephenhawking91552 жыл бұрын

    How can i pay you. You just saved me ❣️❣️❣️

  • @wassmmd8521
    @wassmmd85213 жыл бұрын

    Very nice

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @adammiah235
    @adammiah2354 жыл бұрын

    It is a very good video.......thanks ....

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @muskanpathan7623
    @muskanpathan76236 жыл бұрын

    Wow!!!!

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @nareshsheoran2298
    @nareshsheoran22986 жыл бұрын

    Very nice sir

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @JamSlapper
    @JamSlapper5 жыл бұрын

    MutS and MutL are heterodimers not homodimers, good vid though

  • @sanauzma6192
    @sanauzma61923 жыл бұрын

    pleas sir be lauder i cant heat uhh

  • @eugenealice6839
    @eugenealice68395 жыл бұрын

    nice

  • @NT20817

    @NT20817

    5 жыл бұрын

    rlly nice

  • @aliceeugene6871

    @aliceeugene6871

    5 жыл бұрын

    Hey what’s up Nate ?

  • @NT20817

    @NT20817

    5 жыл бұрын

    Alice Eugène chillin like a villain, n you?

  • @aliceeugene6871

    @aliceeugene6871

    5 жыл бұрын

    Cool, not me, I’m an hard worker today !

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @jinglingu3465
    @jinglingu34657 жыл бұрын

    旺德福!!!

  • @Futurescientist_
    @Futurescientist_ Жыл бұрын

    This is wrong first step hemimethylated GATC pe

  • @user-hf9wy5jp6x
    @user-hf9wy5jp6x3 жыл бұрын

    перевод на русский

  • @tarannumkhatoon5070
    @tarannumkhatoon50706 жыл бұрын

    👌👌👌

  • @crazyfilms6562
    @crazyfilms65626 жыл бұрын

    Very nice

  • @samarrowsmith1396

    @samarrowsmith1396

    3 жыл бұрын

    Thank you! I realise it's been a very long time since I made a video of this nature, but I wanted to ask a couple of questions: how did you find this video and what makes this video work? I'm curious as to how this particular video became successful compared to others, so any feedback is appreciated!

  • @crazyfilms6562

    @crazyfilms6562

    3 жыл бұрын

    Sir it's been 2 years now and I was in 12th standard at that time, after watching your video It made me easier to understand the concept and visualization makes it more memorable, now sir I am doing mbbs and hopefully became a doctor.🙏

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