I led a 4-star Aeon TF that had the following limited ruleset:
No Kinetics, Nature, or Cold Domination
No Ice Blast, Fire Blast, Fire Melee, Battle Axe
No Bio Armor or Rad Armor
No 4star optimized builds, only general PVE builds (my Rad/Rad Corrupter had only 2-3 additional procs that weren't already included in an IO set (like a Glad Javelin Toxic Damage+5 Apocalypses in Proton Volley).
No prep like respecs or acquiring additional accolades beyond what a toon already has
T4 incarnates were obviously allowed because Hardmode was designed specifically with them in mind
I also did not seek any specific powerset combinations other than that I did want an Electric Affinity. Otherwise, I just said I needed roles filled (like debuff, buffs, taunt, etc.) and this is what people had.
Our time was 1:10:~19 and we had 23 deaths.
Team Comp:
Rad/Rad Corruptor (Barrier)
AR/FF Corruptor (Barrier)
FF/AR Defender (Incan)
Psi/Time Corruptor (Barrier)
Grav/Elec Affinity Controller (Clarion)
Stone/Stone Tanker (Barrier for missions 1-2, Ageless for the rest of the TF)
Energy/Elec Blaster (Barrier)
Trick Arrow/Electric Defender (Barrier)
As long as you have the following roles covered, you will be fine: Defense Buffs, Debuffs (Priority: -Regen, -Res, -Heal,-dmg, -tohit), DPS, 2 healers, taunt role.
Fun facts: Hero 1 was hitting our Stone tank through capped Def & resists for ~2,400 damage, and Mr. Rodney, during the Zoe Fight, hit him for ~2,300 damage with an Energy Transfer. So yeah, the healers are a requirement, as well as the tank having more than ~2,500 HP to survive.