It's been 12 years but I still want to thank you for your videos! ❤

@InteractiveBiology

10 ай бұрын

I'm so glad you found it helpful, ベルビーちゃんBelvi-chan. You are welcome. If you haven't already, make sure to subscribe to the channel because I have a lot more content like this coming to help you understand how the human body works.

Thank you very much for your good explanations. I speak French and your language is easy to understand. It is clear and concise. Keep it up.

Honestly, InteractiveBiology is heaven sent. You are like my own personal tutor! My professor always makes all of this sound so foriegn, meanwhile you manage to get me to understand a topic in less then 10 min. THANK YOU SO SO SOOO MUCH!

you so much :') I am studying for a Physiological Psych class and I had lost hope, until I found this video!!

Oh my God Thank you so much Leslie you really wouldn't understand how much help I got from this 10 min clip... THANK YOU!!

You are my physiology HERO. I feel more confident about the course now that I have you around. You are an amazing instructor.

You make it so easy to understand! So thankful for interactive biology tv. It makes me look like a genius

I'm doing a degree in Biomedical Science and I have found your videos so helpful! They are so much easier to understand than anything I have been able to find on the internet or in text books! Thanks so much and I hope the videos carry on!! :-)

I'm a 1st year med student and you couldn't have explained the process more beautifully .. This has been helpful !! Thank you so much!!!

thankyou so much for this, for making the effort , and making this info available. It is a big help. I just wanted to point out for ppl who are seeing this for the first time, that the receptors for the different neuro transmittors are serparate and specific, I wouldnt want ppl to think that you have a channel which opens in reaction to both Ach and gaba / glycine for example, they are different and separate channels.

Thanks a lot... You make my pharmacy course 10 times easier... thank you again :)

Thanks yo, this is 1 million times easier than my lectures. Cheers

Well Sir, I'm a nursing student, and I it took 8 hours to explain what you just explained in 9 min, THANK YOU VERY MUCH

Wow thank you for this!! I've spent a week trying to understand this concept, and you managed to clarify it in under 10 minutes! Thanks a million :)

Once again, a wonderful, clear, concise explanation that changes learning from wrote memorization to understanding and long term retention. You are one of the reasons I am getting As in Anatomy and Physiology. THANK YOU!!!!

you are easily 10 billion times better than my lecturer!

Thank you very much for posting this series of videos! I am LEARNING a lot from them. You explain everything clearly and concisely. Seriously, my grades are improving because of your videos.

Explained so simply!! A million thank yous!!!

wow....that makes soooo much more sense now!! thank you!!! (if I pass my exam it'll be thanks to you!!)

You're videos are amazing. You makes it so clear.

Thank you so much! Watched a 50 minute lecture... made no sense. Watched this along with your synapse video and it's so clear! Keep the physiology videos coming!

Thanks. You make things easy to understand. Please upload more videos like this.

You are awesome! I enjoyed the clip, you are clear, to the point, fast and short:) Thank you much. Wish me luck for my test tomorrow:)

Splendid job in explaining those bio concepts.

wow this is really awesome.....i watch ur videos to understand topics i dnt understand in my physiology class..thank u very much

Thank you for the easy-to-follow tutorial ! Clarified a lot of uncertainties !!!

Very well presented! Thank you!

WOW! this was sooo clear... thank you! My professor could have never explained it this clearly.

Seriously helped me grasp these concepts! You break it all down so easily and clear :)

@ingeborgc Wow, Croatia. That's awesome. So glad to be able to help from such a distance away :) All the best!

Your videos are always soo helpful. Thank you

ok I'm studding bio psychology and for the first time it actually made sense!!! I only wish i found these tutorials sooner bf my test:))))thank you, thank you, thank you!

@Djalitana You are very much welcome. Glad you were able to figure it out!

So helpful! Really clear and at just the right pace. Thank you :)

Thank you! This was great, as most others will agree! I will definitely be watching the other videos!!

@KaTyJbx Awesome. Thanks for the feedback. They will definitely carry on, so stay tuned :)

When you have the monotropic receptor, when the g-protein is activated does it still allow ions to flow to the intracellular part? I know you were talking about how it has a higher volume of response but is that response act as a chemical response or a higher response with the flow of ions?

Wow! This is great! You are a life saver for my neurons! :D Keep up the good work ! Greetings from Croatia.

Thank u so much for ur clear explanation upon this topic, so bless!!!

Awesome....I am a 1st year med student and you have explain it best......

This was very simple and helpful! Thank you! I would, however, like to have heard about the receptors that are inside of the molecule too (ie. for testosterone etc).

dude u r soooooo awesome. u go thru everything i am going thru in my class currently! i "like" or "thumbs ups" all ur vids i watch :D

@Livinglifehigh Well that's awesome. Glad it's helping! All the best with your class!

ok I went back to my book and watch this clip again. now I know it doesn't need to be necessarily sodium Ions , it can be any other ion to get into the cell and depolarise or hyperpolarize the post synaptic neurone or muscle. thank you so much.

Unless you were asking about whether each receptor only allows a specific type of neurotransmitter to activate it. For example, most inhibitory ionotropic receptors use GABA. Many Metabotropic receptors accept different types of neurotransmitters. The important part is where the metabotropic receptor is located, not necessarily the types of neurotransmitter it accepts.

This was so helpful, thank you so much!

This was perfect. Thank you so much!

it was so helpfull!! my language is not English but steel it was so easy to me to understand it! so, thank you so much for this!!

So clear..!! It really helped me!

thank you! this helps illustrate the concept well!

Great explanations, thanks a lot

This is because the IPSP or EPSP we are talking about is on ANOTHER neuron across the synaptic cleft (space). You are right about the refractory period though, just that we are talking about two neurons here, not just one.

you are incredible!!!! I defiantly owe a lot to your videos. Thank you so much!!

@sakiwieug That's great to know. Thanks for the comment. Stay tuned for MANY more!

very good explanation I am now able to visualize the action at the synapse thanks.

That was extremely helpful. Thank you.

This was so helpful thank you so much!!

@MrDonoterase Hi there. Glad to know you are finding value in the videos. Sometimes watching a concept works better than listening to a concept. Thank you for leaving a comment and stay tuned for the many more videos to come :)

Good stuff sir 👍

that was soooo coooool..thanks bro...

@TimmysMummy Hey, thanks for adding that bit of info. Yes indeed. Each receptor is different and specific. All the best!

This was so much clearer than my lecture thank you

@tearsofmars13 Well thank you. Glad you found value in it. Stay tuned for many more to come :)

Thank you! After this i finally understand it!

good vid well explained and set out

Great stuff!

@fly5grl It definitely is complex stuff, which is why I love it. When the Neurotransmitters bind to metabotropic receptors, there can be a variety of responses, depending on the type of receptor and even the process that it's influencing. There's no one way. It can involve protein kinases, and many other enzymes to control many different processes.

thank you so much, it really helps me a lot!

This is awesome help I get so easily do fused with biology

@iam4someone Glad to hear. Stay tuned for more

Awesome . well done !

Thank you so much for this!!

@helixzzz The name musarinic doesn't refer to Muscle. It refers to muscarine, which is a substance that mimics the effect of ACh on these specific receptors. They are located in many parts of the body, including muscles. Hope that helps!

Realy helpful! thanks a lot ;)

@DoonGirl18 You are very much welcome. Glad to know the videos are helping you to understand your crazy lecturer, lol. I plan on doing many more, so stay tuned. All the best!

Would love a video about M1, M2 and M3 muscarinic receptors!

I like the format and your explanations are very easy to follow. However, I'm still I confused with the functions of G-proteins...Can they directly open or close ion channels located on the plasma membrane or do they only do this indirectly with the 2nd messenger? How do these actions influence EPSP's? THANK YOU FOR YOUR LESSONS!!

hi sir thanks for the Vid they are very helpful, i have a question u was talking about Muscariniq receptor so its a metabotropic receptor or not ? and the neurotransmitter bind with the muscariniq receptor and then activate the G proteine ? or just bind with the G prot? x)

thank you soo much for such a clear explanation :)))

Excellent interpretation,

hi, I have different information now. at synaptic Clift lots of calcium Ions ca2+ enter the membrane or lots of sodium Na+ ? thank you for your dedication.

Thank you that's such a good explanation :) but i have one question .. we have learned that a.p have a property of one way propagation.. so the post synaptic cant receive an a.p if it's already excited.. right? also the ipsp is also to stabilize the membrane rather then to hypopolarize.. So the question is.. how does the the ipsp stabilizes already excited membrane? I mean the only way for the neuron to recieve a second potential is to be in refractory period .. Hope you understood my confusion.

What kind of ionotropic receptors are there for GABA and glycine? Is that nicotinic receptors as well?

you are wonderful! Thank you!

@InteractiveBiology

10 жыл бұрын

You are welcome :)

@stephypaul571 That's great to hear. Hope your exam went well :)

@Chipotle3333 We're so glad to know you find value in it. We hope you aced it. Keep on coming back for more Biology videos! :)

Mr. Samuel, first, I truly enjoy your videos. Thank you. my dilemma: I have been searching for an animation regarding the GABA the synthesis, storage and release of GABA, starting with glutamate and catalyzed by GAD using Vitamin B6 as a cofactor. I have a huge exam to acquire my masters, was never a fan of cycles and synthesis, do you have any videos of this sort? Thank you!

@RemnantJC

8 жыл бұрын

+Mary M think it may be called the GABA shunt? My head is spinning, there is so much material I have to know, over 2 years of grad school. Thank you for your help. Mary

I wanted to find out if you block a muscarinic receptor what will happen? I am studying neuroleptic medications and trying to understand the way these work. I am not sure you can help, but anything would be appreciated. Thanks

@phucbeo111 That's the goal :) Thanks for your comment!

@msss432 I dont think any neurotransimitter can bind to any recepter, but there is a variety that one can bind to. ACh does bind to both nicotinic (which I think has excitatory effects) and muscarinic (which can be either excitatory or inhibitory and only occurs in the parasympathetic system). Depending on where the synapse leads to (muscle fiber, neuron, gland, etc) determines which receptors are available for the neurotransmitter.

@ONWUDIACHI24 You're welcome :) Do stay tuned for more!

@msss432 Oh, I'm sorry. Leslie will not be able to entertain any more questions as he is busy with a lot of stuff right now, and creating more videos for the site. He'll be tackling more topics so, stay tuned for more!

how does the body decide which neurotransmitter is getting released to either excite or inhibit??? Ik they are in the vesicles of the pre synaptic membrane but are there multiple vesicles with different neurotransmitters

is it only acetycholine that acts on muscarine and nicotine receptors or can other transmittors act on them as well?

i have qustion.. can it be electical conducting instead of nerutransmitters .. or it habe to me chemically conducted

it's very helpful

thank you sir!

Well done

Thanks guys for this video but I got some problems with some concepts. With my knowledge, I knew that there are 2 kinds of systems which are adrenergic system and cholenergic. But you just showed 2 receptors in cholenergic sys ( nicotine and muscarine), therefore, I wonder where are alpha and beta receptors in adrenergic sys. Are these receptors involved in the 2 kinds receptors that you had mentioned before ( Inotropic and Metatropic). By the way, can you figure out the other neurotransmitters ( Dopamine,Nor, Epi, Serotonin, Gaba, Glutamate) with theirs approriate receptors and functions. I am hopeful to seeing reply from you.

@jakeorin334

9 жыл бұрын

Dopamine, Norepi, Epi all function in the SNS and are G-protein coupled reactions and are thus metabotropic. The video mentioned that GABA and Glutamate as ionotropic but they also can both work in the metabotropic side, which is where most seratonin receptors fall.

excellent...!!