Iowa Institute of Human Genetics

Iowa Institute of Human Genetics

Growth in human genetics research is driving the increasing use of genetics in medical practice. The environment of the Iowa Institute of Human Genetics (IIHG) provides unique opportunities to make progress in both the discovery and translational phases of human genetics. The IIHG is a statewide resource that promotes clinical care, research, and education in human genetics and is focused on bringing personalized genomic medicine to the state of Iowa.

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  • @muhammadfahmi9804
    @muhammadfahmi9804Ай бұрын

    May i ask, how exactly do you find these universal primers? Do we just type 16s in NCBI, then find the primer for that? Because usually, in NCBI, they're species specific, not umiversal

  • @sefatergbashi
    @sefatergbashiАй бұрын

    Awesome!

  • @quantumchase
    @quantumchase2 ай бұрын

    I am currently studying Wilson Disease, and based on the literature I have gathered, there is no well-established genotype-phenotype association. Also, there are multiple mutations across all 21 exons of the ATP7B gene. But most of the literature also state that they are using ACMG guidelines for classifying variants. Any comment on that?

  • @frankfeng3737
    @frankfeng37374 ай бұрын

    Very good presentation. thanks for sharing.

  • @ademolaolofin
    @ademolaolofin10 ай бұрын

    Awesome, thanks a lot for this video

  • Жыл бұрын

    Thank you Iowa Institute for Human Genetics. Greetings from a bioeng grad student from Universidad del Cauca, Colombia.

  • @kseniaalexandrova5298
    @kseniaalexandrova5298 Жыл бұрын

    Thank you very much for this wonderfully presented material.

  • @jahnvihora403
    @jahnvihora403 Жыл бұрын

    Great video. Thank you!

  • @jessehines4044
    @jessehines4044 Жыл бұрын

    I don't understand. If you want to detect what genes are off or on and by how much they are expressed then why not just use epigenomics instead of transcriptomics?

  • @Johan-et9sx
    @Johan-et9sx Жыл бұрын

    lache la traduction en français ta voix de cancéreux là

  • @researchstudentacademy3512
    @researchstudentacademy3512 Жыл бұрын

    Best lecture on metagenomics, wish for further information 👌

  • @MissAsdfb99
    @MissAsdfb99 Жыл бұрын

    Could you please share the link

  • @bostonwren9203
    @bostonwren92032 жыл бұрын

    Wish I could see this great video earlier. So many questions solved.

  • @olgaantonova5939
    @olgaantonova59392 жыл бұрын

    great webinar!

  • @0102murphy
    @0102murphy2 жыл бұрын

    Is this just applied to gremlin variant? Can it be applied to somatic variant?

  • @davidnduuru8516
    @davidnduuru85162 жыл бұрын

    Thank you 10x team and the host. Can I get a copy of the slides to use for my rehearsals? I am trying to understand the work flow of single cell seq to use on my postgraduate project and this could be of great help. Again, thank you so much for the presentation.

  • @noereyna2553
    @noereyna25532 жыл бұрын

    Hello, awesome video. Could the .html be shared? thanks

  • @JesusMiguelH96
    @JesusMiguelH962 жыл бұрын

    Could you please give us access to the document used in the video?

  • @mr.e-machine9422
    @mr.e-machine94222 жыл бұрын

    I have chronic gut issues that comes along with all other kinds of side effects. Is there any way to get into this study as a patient? I have an appointment at Ohio state coming soon. My life is falling apart and most of my doctors don't seem to understand the severity of it.

  • @maewoods1044
    @maewoods10442 жыл бұрын

    This is such a helpful video. Thank you so much!

  • @grsbiosciences
    @grsbiosciences2 жыл бұрын

    Could you please give link to access data shown in video

  • @laurencollen8543
    @laurencollen85432 жыл бұрын

    This was excellent -- are slides publicly available as implied at the end of the lecture?

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Lauren, I don't believe they are at this time. You could email Diana directly and ask for a copy.

  • @zc7504
    @zc75042 жыл бұрын

    thank you so much for the presentation! well explained!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Glad it was helpful!

  • @lailadababnahas9969
    @lailadababnahas99692 жыл бұрын

    thanks

  • @learningtime1367
    @learningtime13672 жыл бұрын

    Dr. Michael mentions at 48:17 that he did a webinar on pathway analysis. Could you please share the link? Thank you!

  • @RyeCA
    @RyeCA2 жыл бұрын

    This video is a great summary of Metagenomics!

  • @EtandoAAyuk
    @EtandoAAyuk2 жыл бұрын

    Thanks so much for the video. Very informative. Uts my first time to read about metagenomics because I have an interest for my PhD and your video motivates me. Thanks 😊

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    You're very welcome!

  • @Dr.Mahesh_H
    @Dr.Mahesh_H2 жыл бұрын

    Thanks for the video. Please make a video on chip seq analysis in R starting with GEO dataset, there is no proper one on internet so far.

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Great idea...we'll try to make that happen!

  • @booJay
    @booJay2 жыл бұрын

    Nice video, thanks Michael! I'm a molecular biologist who struggles with the basics of bioinformatics so this really helped.

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Great to hear!

  • @weewweeho
    @weewweeho2 жыл бұрын

    Thank you very much Dr. Kolbe this is a very useful and informative overview.

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    You are very welcome

  • @simplychem4160
    @simplychem41602 жыл бұрын

    Thanks a lot. very well explained.

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Glad it was helpful!

  • @utsubo7063
    @utsubo70632 жыл бұрын

    This is wonderful information about bioconductor and Public database!

  • @1973vgc
    @1973vgc2 жыл бұрын

    thanks for sharing, greetings from Spain!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75842 жыл бұрын

    Thanks for watching!

  • @azchannel4045
    @azchannel40452 жыл бұрын

    theng you...

  • @mikephelan5940
    @mikephelan59402 жыл бұрын

    This is really terrific, thank you so much for providing it to all. The 10X folks did a great job IMHO: very well organized and clear, many tips on how to succeed. Hoping to run my first 10X experiment very soon and this is very reassuring information to have at hand. Hopefully I can find a pdf of these presentations, but if not I'll just take screen captures. Cheers!

  • @muffinman1
    @muffinman13 жыл бұрын

    Informative and concise. Thanks!

  • @huanhuanzhao105
    @huanhuanzhao1053 жыл бұрын

    Great video! Thank you!

  • @tvmcharnet
    @tvmcharnet3 жыл бұрын

    Really appreciate this explanation, as I'm having my first go at writing a protocol for a job.

  • @acidclarity_
    @acidclarity_3 жыл бұрын

    this is amazing helpful! wow thank you 10x !!

  • @StevenMGruber
    @StevenMGruber3 жыл бұрын

    Great presentation! Systematic and very easy to follow, thanks for putting this together!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Glad it was helpful!

  • @muffinman1
    @muffinman13 жыл бұрын

    BA1 is benign-standalone not benign-automatic. Its weight is so heavy that just that criteria itself can cause the variant to be considered benign as the name implies.

  • @dianakolbe8944
    @dianakolbe89443 жыл бұрын

    Yes, the formal name is benign stand-alone. In practice, unless dealing with a well-known and established high-frequency pathogenic variant such as the global exception list, if BA1 is satisfied, the variant can be automatically considered benign without considering other criteria.

  • @Shaq0112
    @Shaq01123 жыл бұрын

    Excellent!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Many thanks!

  • @negarashariastani1863
    @negarashariastani18633 жыл бұрын

    Thanks. Very well-described

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Glad it was helpful!

  • @pedroosorio5012
    @pedroosorio50123 жыл бұрын

    Great video! Cheers

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Thanks!

  • @betulbitirsoylu8040
    @betulbitirsoylu80403 жыл бұрын

    Great! So explanatory. Thank you.

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Glad it was helpful!

  • @amybraun5924
    @amybraun59243 жыл бұрын

    Thank you

  • @muskduh
    @muskduh3 жыл бұрын

    thanks

  • @benjaminsimpson6691
    @benjaminsimpson66913 жыл бұрын

    Could you guys potentially consider copy-number variant discovery using NGS data? I work at a university and most of our research staff no about copy-numbers and the data you get back, but have no clue how this data is derived. The resources available are pretty high level!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    We will consider CNV analysis for a future workshop. Thanks for the suggestion!

  • @dantekillbourne4747
    @dantekillbourne47473 жыл бұрын

    Im an undegrad writing a thesis for my honors program. COVID destroyed my proposal and had to switch up to a remote RNAseq analysis - you've just saved my college career sir thank you

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    Glad you found the information helpful! Good luck with your project!

  • @lizo.3
    @lizo.34 жыл бұрын

    This is very informative. Especially for beginner PhD students. Thank you!

  • @iowainstituteofhumangeneti7584
    @iowainstituteofhumangeneti75843 жыл бұрын

    You're very welcome!