R in Pharma

R in Pharma

R/Pharma is a nonprofit focused on delivering a scientifically & industry oriented, collegial event focused on the use of R in the development of pharmaceuticals. The conference covers topics including reproducible research, regulatory compliance and validation, safety monitoring, clinical trials, drug discovery, research & development, PK/PD/pharmacometrics, genomics, diagnostics, immunogenicity and more. All are discussed within the context of using R as a primary tool within the drug development process. The conference showcases the current use of R that is helping to drive biomedical research, drug discovery & development, and clinical initiatives.

R/Pharma is dedicated to providing a harassment-free conference experience for everyone regardless of gender, sexual orientation, disability or any feature that distinguishes human beings. For more information, please see the R Consortium code of conduct.

Observable Plots

Observable Plots

Quarto All the Things!

Quarto All the Things!

Пікірлер

  • @canarese
    @canarese17 күн бұрын

    Its great for learning. I am getting errors such as Deprecated etc. Have any updated one?

  • @kennedymwavu
    @kennedymwavu24 күн бұрын

    this is so cool!

  • @Smackerz1988
    @Smackerz198829 күн бұрын

    Someone's an AEW Fan

  • @hemantishwaran5741
    @hemantishwaran5741Ай бұрын

    Really great. Just wish you’d do things in base R. I’m an advanced user and avoid ggplot and tidyverse so wish you’d stop pushing those tools

  • @suryoputr9344
    @suryoputr9344Ай бұрын

    I'm a newbie in R. Can you explain why would you avoid ggplot and tidyverse? Is there something inherently wrong in them?

  • @hemantishwaran5741
    @hemantishwaran5741Ай бұрын

    @@suryoputr9344 As a developer, simpler is better. You want code that is easy to debug, easy to understand, and that will stand the test of time. Just using one command of tidyverse in an R package commits you to its ridiculously large number of dependencies which makes your code less stable. As for ggplot, it produces beautiful figures very quickly, but for EDA purposes you don't often need that and you will end up wasting time. Especially if you want to tweak your plot in any way that is different. As a newbie, you might appreciate the ease at which you can generate high quality graphics and the seemingly easy way to manipulate data with tidy verse, but as you get more advanced you will recognize them as being overly complicated.

  • @djangoworldwide7925
    @djangoworldwide79256 күн бұрын

    ​@@suryoputr9344No reason. Learn and use the tidyverse.

  • @eubutuoy
    @eubutuoyАй бұрын

    What if you need to optimize two parameters from two different studies? For example, ka from oral bolus in vivo data and clearance from iv study? How do you optimize ka and clearance to fit both studies with one pbpk model?

  • @sunilgupta2156
    @sunilgupta2156Ай бұрын

    Thanks for a great presentation!

  • @mursalimali1629
    @mursalimali1629Ай бұрын

    O

  • @marwolaeth111
    @marwolaeth111Ай бұрын

    That's fascinating! 🤩 Your team makes some of my dreams come true. I'll try my best to make the best use of it

  • @johnhhu2137
    @johnhhu21372 ай бұрын

    cool

  • @haraldurkarlsson1147
    @haraldurkarlsson11472 ай бұрын

    This is a very well constructed lecture and reproducible (all the data and source code is given on github). A nice scaffold to build your own lectures on and expand. My only complaint is that the transitions are often not clear and bit rugged (e.g. spend a lot time on LASSO but then use Logistic Regression).

  • @haraldurkarlsson1147
    @haraldurkarlsson11472 ай бұрын

    If you are worried about which columns are picked in step_normalize() and you all want columns with values greater than 1 then I believe this code works: step_normalize(where(~is.numeric(.x) && any(.x > 1))). Now what the author uses in the video is more straight forward and thus simpler but if you have a lot of columns the first approach might be safer.

  • @haraldurkarlsson1147
    @haraldurkarlsson11472 ай бұрын

    It is hard to sit there and look at a relatively small font (I know you can expand the view) on a light background and not get eye strain. I recommend using a dark background in RStudio.

  • @haraldurkarlsson1147
    @haraldurkarlsson11472 ай бұрын

    If you are starting out with tidymodels then yo might be confused since a little of details are left out. Naturally you cannot cover such a big subject in a short lecture. Those needing more information might want to look at "Tidy Modeling with r" by Kuhn and Silge(2022). A free ebook version is available online.

  • @PositPBC
    @PositPBC2 ай бұрын

    Really nice talk. Thank you for pioneering this work!

  • @dexterpante
    @dexterpante3 ай бұрын

    Great video tutorial, looking forward for more {Teal} Tutorial

  • @RinPharma
    @RinPharma2 ай бұрын

    We hope to have more at R in Pharma 2024 October 29, 30, & 31st. Workshops will run the week before.

  • @300yardcarry
    @300yardcarry3 ай бұрын

    cool!

  • @vinitakale8823
    @vinitakale88234 ай бұрын

    On running the following code snippet # Baseline Characteristics ---- adsl_bl <- pre_adsl %>% derive_vars_transposed( select(vs, USUBJID, VSTESTCD, VSSTRESN, VSBLFL), # Dataset to transpose and merge onto by_vars = vars(USUBJID), # Merge keys key = VSTESTCD, # Names of transposed variables value = VSSTRESN, # Values of transposed variables filter = VSTESTCD %in% c("HEIGHT", "WEIGHT") & VSBLFL == "Y" # Restrict records to just height and weight ) %>% # Do some cleanup rename(HEIGHTBL = HEIGHT, WEIGHTBL = WEIGHT) %>% select(-VSBLFL) %>% mutate(BMIBL = compute_bmi(HEIGHTBL, WEIGHTBL)) I am getting the following error. Error in `assert_list_of()`: ! Each element of `arg` must be an object of class/type 'symbol' but the following are not: ✖ Element 1 is an object of class 'quosure' --- Backtrace: ▆ 1. ├─pre_adsl %>% ... 2. └─admiral::derive_vars_transposed(...) 3. └─admiraldev::assert_vars(by_vars) 4. └─admiraldev::assert_list_of(arg, "symbol", named = expect_names, optional = optional) Run rlang::last_trace(drop = FALSE) to see 1 hidden frame. Can you please guide?

  • @carvalhoribeiro
    @carvalhoribeiro4 ай бұрын

    Great presentation. Thanks for sharing this.

  • @siriyaksiriyak6067
    @siriyaksiriyak60675 ай бұрын

    good refresher, 😇

  • @ivorycloudofficial
    @ivorycloudofficial5 ай бұрын

    Can you add timestamps/sections to your video please?

  • @haraldurkarlsson1147
    @haraldurkarlsson11475 ай бұрын

    This is excellent! I like the level of depth.

  • @RinPharma
    @RinPharma2 ай бұрын

    Great to hear! We hope to have more at R in Pharma 2024 October 29, 30, & 31st. Workshops will run the week before.

  • @abuyasinsabdahany3259
    @abuyasinsabdahany32596 ай бұрын

    Thank you

  • @fburton8
    @fburton86 ай бұрын

    Great demo, so informative! You explained Observable Plots really well.

  • @divanaristoburger8295
    @divanaristoburger82957 ай бұрын

    This is amazing work!!

  • @gypcasinoable
    @gypcasinoable7 ай бұрын

    The reports are just amazing. Thank you for sharing!

  • @meredith0322
    @meredith03227 ай бұрын

    I'm able to install ggsurvfit package, but cannot library it. any suggestions for the issue?

  • @RinPharma
    @RinPharma6 ай бұрын

    Hi @meredith0322 - you might ask the question here: github.com/pharmaverse/ggsurvfit/issues

  • @user-vb1ck9yq3y
    @user-vb1ck9yq3y7 ай бұрын

    This is outstanding presentation, I find it very useful. Thank you Daniel! Wojtek. W.

  • @fburton8
    @fburton87 ай бұрын

    Nice one!

  • @i.meijer-samson3466
    @i.meijer-samson34669 ай бұрын

    💡

  • @DieuwkeHettinga
    @DieuwkeHettinga9 ай бұрын

    🎉 wat een goede presentatie

  • @mikebartlett6356
    @mikebartlett63569 ай бұрын

    In 1997 CDISC was formed to harmonise data standards across the industry and there were just as many nay-sayers for that initiative. Their work continues and admiral's is just beginning by comparison. admiral has the potential to make a similar impact on the industry.

  • @newbestofthis4422
    @newbestofthis44229 ай бұрын

    Thank you! I signed up for this course when it first came out and Ilove it. I look forward to taking your new course. As a biostatistician in public health I was desperate to learn pharmaceuticals workflow and their reporting system, there isn't enough resources unfortunately especially for R.

  • @RinPharma
    @RinPharma9 ай бұрын

    Connect with Michael on LinkedIn, if you’d like to continue the discussion after r/pharma: www.linkedin.com/in/michaelrimler/

  • @RinPharma
    @RinPharma9 ай бұрын

    Project GitHub: github.com/phuse-org/OSTCDA Join the Discussions and leave your perspectives, opinions, links, references, presentations, to help us cultivate a comprehensive digest of the current state of the industry using OS tech for clinical data analytics and reporting

  • @RinPharma
    @RinPharma9 ай бұрын

    Great talk!

  • @tataphani
    @tataphani9 ай бұрын

    Wonderful presentation

  • @ayushgupta7731
    @ayushgupta77319 ай бұрын

    Amazing

  • @mayank7jan
    @mayank7jan9 ай бұрын

    Thank you 🙏🏻

  • @RinPharma
    @RinPharma9 ай бұрын

    github.com/agstn/RPharma23

  • @abhilashbhagat2949
    @abhilashbhagat294910 ай бұрын

    Lovely explanation John!

  • @PotatoesPlease31
    @PotatoesPlease31 Жыл бұрын

    3rd Module starts at 1:14:20 4th Module starts at 1:31:05 5th 1:42:12 6th 2:11:54

  • @nndegwa1
    @nndegwa1 Жыл бұрын

    love it!

  • @chughag
    @chughag Жыл бұрын

    Thank you Micheal, Atorus Research and R in Pharma for conducting this workshop and posting it online!! This is super helpful!!

  • @denizgoktas1535
    @denizgoktas1535 Жыл бұрын

    Thanks for this instructive and worable presentation.

  • @joycesposato5905
    @joycesposato5905 Жыл бұрын

    5:23

  • @Ruben-un1mr
    @Ruben-un1mr Жыл бұрын

    'Promosm' 🙈

  • @explore5709
    @explore5709 Жыл бұрын

    This video puts the mind of SAS Programmer at ease to some extent, that creating a Dataset in R is not that Hard. But at the end of the video it does feel what's will be the future of Clinical Programming ?

  • @nancyanderson5413
    @nancyanderson5413 Жыл бұрын

    Creating dataset is not hard at all in R, and SAS is so expensive, and all the certifications are extremely expensive too. R is a community of scientist, data scientist, and programmers that want people to really learn and understand. Also once you talk with a SAS representative and dig deeper they take a lot of the innovations of the R GNU community. The regular user of SAS does not realized that but the programmers do, and it is awful that a company make a lot of money taking what in reality is open source.

  • @fburton8
    @fburton8 Жыл бұрын

    The first link in the dooblydoo is the talk slides.

  • @PasqualeMerella
    @PasqualeMerella Жыл бұрын

    Thanks for the video. May I got a github source code of that app in R? thanks so much

  • @hplcdadong
    @hplcdadong2 жыл бұрын

    Interesting topic,but video quality not that good

  • @alexandregeorgelustosa5969
    @alexandregeorgelustosa59692 жыл бұрын

    Top 🙌