Oligonucleotide Therapeutics Society

Oligonucleotide Therapeutics Society

The Oligonucleotide Therapeutics Society (OTS) is an open, nonprofit forum to foster research and development of oligonucleotide therapeutics.

The Founders’ vision was to bring together the expertise from different angles of oligonucleotide research to create synergies and to bring the field of oligonucleotides to its full therapeutic potential. A new era of oligonucleotide drugs was envisioned that would change the landscape of therapeutic modalities.

Oligonucleotide therapeutics are now being used to successfully treat diseases and have the potential for widespread application. Over 100 treatments are in development for common conditions, including cancer and Alzheimer’s disease, as well as rare diseases. Incredibly, oligonucleotide therapeutics have also been used to create an individualized treatment for one single person with a rare, fatal disease.

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  • @theguywitharedsuitandtie2942
    @theguywitharedsuitandtie29422 күн бұрын

    Amazing informative video, I liked it a lot! And props to the speaker, she's really clear and experienced while delivering difficult points throughout the video.

  • @color_pens5542
    @color_pens5542Ай бұрын

    Based on this video, we're now in the prime time for gene editing.

  • @marks8052
    @marks8052Ай бұрын

    any inroads into MPN blood disorders?

  • @Satyanarayanakota-kl8ib
    @Satyanarayanakota-kl8ibАй бұрын

    Very informative and in-depth lecture on oligonucleotides

  • @marks8052
    @marks8052Ай бұрын

    so what recourse is there for those of us who have Myeloproliferative neoplasms, like Polycythemia Vera?

  • @charlescabana7849
    @charlescabana78494 ай бұрын

    Thank you.

  • @ataabbas9357
    @ataabbas93574 ай бұрын

    Congratulations to Dr. Sudhir Agarwal, a giant in the field!

  • @emmottlegan2988
    @emmottlegan29885 ай бұрын

    🤣 P r o m o S M

  • @niamcd6604
    @niamcd66046 ай бұрын

    Yet again, the next white overly praised guy. What a surprise.😮😮😮

  • @niamcd6604
    @niamcd66048 ай бұрын

    Sweet universe of nonsense!! How is it possible uni professors are REQUIRED to actually speak the language in which they deliver a conference!?? For crying out loud, the French are truly the worst! And I am bilingual myself!!!

  • @IWWtNP.
    @IWWtNP.11 ай бұрын

    thanks

  • @EdT.-xt6yv
    @EdT.-xt6yv11 ай бұрын

    5:29

  • @edthoreum7625
    @edthoreum7625 Жыл бұрын

    17:00

  • @new1all501
    @new1all501 Жыл бұрын

    really nice work!

  • @JayantaKundu-ym7wg
    @JayantaKundu-ym7wg Жыл бұрын

    Amazing work...

  • @changhooncho8195
    @changhooncho8195 Жыл бұрын

    Great Talk, and great job. Dr. Lee.

  • @ajsethi9576
    @ajsethi9576 Жыл бұрын

    A beautiful lecture with the benefit of hindsight.

  • @haldanesghost
    @haldanesghost Жыл бұрын

    The absolute GOAT

  • @nooral-rawi8004
    @nooral-rawi8004 Жыл бұрын

    Incredible speaker with a very comprehensive presentation, thank you for this!

  • @thihuynh6048
    @thihuynh6048 Жыл бұрын

    Thank you so much very helpful. May I ask about some of the design tools or software for miRNA/ anti-miRNA that I can use, please? I am a beginner in this field. Thank you so much.

  • @julzee111
    @julzee111 Жыл бұрын

    It’s quite obvious that science is just beginning to understand the function of RNA and DNA for that matter. So maybe someone can explain to me, why the world would be receiving An mRNA vaccine that has no long term testing. That has skipped animal trials. Unless your objective is genocide, why in the world would this be released onto the public

  • @isomeralpha3864
    @isomeralpha3864 Жыл бұрын

    what type of software do you recommend while working with aptamers

  • @theman36951
    @theman369512 жыл бұрын

    Thank you for making this available to the public.

  • @DontCancelMeBro
    @DontCancelMeBro2 жыл бұрын

    The same way you synthesize or use gain of function on new virus species. I mean, the coronavirus shares a part of the same sequence as Moderna mRNA vaccine. Gotta love this plandemic.

  • @Gnefitisis
    @Gnefitisis2 жыл бұрын

    Always look forward to these vids!

  • @zachocracy
    @zachocracy2 жыл бұрын

    18:15 So that's why Moderna used a "platform approach" to assume tox and biodistribution data of similar LNPs while stating the payload inside is irrelevant? [Source] Joseph Senn Labroots Webinar _(had to screencap bc they deleted off YT)_

  • @zachocracy
    @zachocracy2 жыл бұрын

    Figured my comment would be deleted for putting the **title,** bc YT loves censorship: _Evolution of a Platform Based Non-Clinical Assessment Approach for Vaccines_

  • @fleurdepapaye9635
    @fleurdepapaye96352 жыл бұрын

    Chemist, back to the bench!

  • @boblee3322
    @boblee33222 жыл бұрын

    Wow. amazing speaker. Great talk!

  • @arshadhussain3532
    @arshadhussain35322 жыл бұрын

    The MBBS (Bachelor of Medicine and Bachelor of Surgery) is a course that involves 4 years of study

  • @sakibfarazi1025
    @sakibfarazi10252 жыл бұрын

    Need hemophilia A, cure hurry up

  • @20acivi08
    @20acivi082 жыл бұрын

    to much "uuhmmm"

  • @barbarafogle3541
    @barbarafogle35412 жыл бұрын

    I don't trust anyone who uses uh uh uh in every sentence. If it were a drinking game you would die.

  • @barbarafogle3541
    @barbarafogle35412 жыл бұрын

    Kinda like how fast they built the bomb.

  • @sakibfarazi1025
    @sakibfarazi10252 жыл бұрын

    Hemophilia A hurry up

  • @expandingviews
    @expandingviews2 жыл бұрын

    Great talk. Thanks for this presentation!

  • @Jaanvisabale-s1411
    @Jaanvisabale-s14112 жыл бұрын

    Hello mam

  • @sakibfarazi1025
    @sakibfarazi10252 жыл бұрын

    hemophilia A

  • @sakibfarazi1025
    @sakibfarazi10252 жыл бұрын

    hemophilia A cure need hurry

  • @MrRomiBajwa
    @MrRomiBajwa2 жыл бұрын

    we need more data 🤓

  • @alexandersasha9419
    @alexandersasha94193 жыл бұрын

    I am super excited that Dr Madida 's herbal medicine that my boyfriend found on KZread was able to cure us of our herpes virus.

  • @hajarowji8066
    @hajarowji80663 жыл бұрын

    It was a great talk.Thanks

  • @keithurban8578
    @keithurban85783 жыл бұрын

    Hepatitis B can be treated reach out to Dr.Ayomede on his KZread channel for permanent cure

  • @fahimanwar94
    @fahimanwar943 жыл бұрын

    Thanks for sharing! In my opinion, it is ASO's that will fix diseases like ALS, MS, etc. It seems promising in treating SMA.

  • @arindampal1772
    @arindampal17723 жыл бұрын

    Can we get the slides?

  • @smartmedicin
    @smartmedicin3 жыл бұрын

    Great presentation :-) Thanks.

  • @oligonucleotidetherapeutic7484
    @oligonucleotidetherapeutic74843 жыл бұрын

    Glad you liked it!

  • @mohammedal-hammadi5085
    @mohammedal-hammadi50853 жыл бұрын

    Thank you, it's so clear

  • @abhijith_jain
    @abhijith_jain3 жыл бұрын

    Hi, can Ataxia Telangiectasia be treated with antisense oligonucleotide gene therapy ?

  • @oligonucleotidetherapeutic7484
    @oligonucleotidetherapeutic74843 жыл бұрын

    Yes, ASO therapies are in development. To my knowledge there is an n=1 trial ongoing see www.atcp.org/a-t-aso-gene-therapy-trial-continues/

  • @taffeymylove
    @taffeymylove3 жыл бұрын

    It seems that MiRNA therapy has a bright future. When can we get an actual cancer medicine ?

  • @wenqingli9319
    @wenqingli93193 жыл бұрын

    After 4 yrs, how many CMOs have the ability to produce nucleotides in a large enough amount?

  • @crisprtalk6963
    @crisprtalk69633 жыл бұрын

    48:15 That one figure predicts the death of all standard AAV gene therapy companies. Nice work there!