In vitro fertilization (IVF) is a complex process, and sometimes, even after a successful embryo transfer, the IVF cycle may fail.
In this informative video, Dr. Jay Mehta, Mumbai, a leading fertility specialist, delves into the complexities of IVF cycle failures and answers questions like, Why does IVF fail even after a good embryo transfer? and what to do next?
00:00 Introduction: Why does IVF Cycle Fail after doing an embryo transfer
00:18 Blastocyst transfer
- Blastocyst transfer is a fertility technique where embryos are cultured in the laboratory for 5-6 days after fertilization, allowing them to develop into blastocysts before being transferred into the uterus.
- Blastocyst transfer has been shown to improve pregnancy rates at an earlier stage. This is because blastocysts are more likely to implant in the uterus.
1:15 What happens after embryo is inserted?
- The embryo after it is transferred well into the uterus , which is well prepared for implantation, is supposed to attach to the uterus well.
- After implantation of embryo, the embryo starts to produce hormones, including human chorionic gonadotropin (hCG), which is responsible for maintaining the early pregnancy and supporting the corpus luteum in the ovary.
- The embryo releases signals that help support the uterine lining and prevent it from shedding, which would result in the loss of the pregnancy or IVF failure.
01:44 Implantation of embryo
- The embryo reaches the uterus, it undergoes a process called apposition, where it comes into contact with the endometrial lining.
- Implantation is a complex and highly regulated process that is essential for the establishment and maintenance of pregnancy.
- No one knows where the embryo would attach to which endometrium, even if it is genetically tested euploid embryo.
02:50 Endometrial thickness
- Endometrial thickness is an important factor in the success of IVF treatment, as it can impact embryo attachment and implantation.
- The endometrium should be thick enough to provide a suitable environment for embryo implantation. The optimal thickness varies but is generally considered to be between 7-9 millimeters.
03:27 Implantation ratio
- The implantation ratio is an important indicator of the likelihood of a successful pregnancy following IVF treatment.
- At a good fertility clinic the success rate is around 40-50%
Whether you're considering IVF treatment or have experienced IVF cycle failure, this video offers valuable insights and guidance from Dr Jay Mehta, Mumbai to help you navigate your fertility journey with knowledge and confidence. Subscribe to Dr. Mehta's channel for more informative videos on fertility treatments and reproductive health.
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About Dr Jay Mehta & Shree IVF Clinic
Dr Jay Mehta is the Scientific Director of Shree IVF Clinic, a Luxury Facility for Advanced Assisted Reproduction and Advanced Pelvic Surgery in Mumbai. He is a very well-known Fertility Specialist and is one of the few specialists in the country who is also an extremely sound Embryologist and Andrologist.
From the year 2018, Dr Jay Mehta converted the clinic into a Program that doesn’t allow the use of Donor Sperm. Currently, the clinic practices the DONOR Program in less than 1% of its patients. This is one of the factors which is mainly responsible for the clinic being extremely popular for Fertility Treatments amongst patients.
The clinic is one of the busiest IVF Clinics in Mumbai. It is consistently rated by patients and fellow gynaecologists as one of the Top Fertility Clinics in the city.
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