"We finally understand why bats live so long" - and then a list of things we DON'T fully understand about the perplexing biology of bats. Still fascinating, but the answer you promised is... still speculative.

@petevenuti7355

3 ай бұрын

I would have been just as interested in watching if he said, "we now have a clue" or "we now have a hint" instead of "we now understand".

@grapesofhypocrisy9842

3 ай бұрын

I heard high intensity exercise creates ozone and certain cells can wield ozone as a weapon. Flying might produce ozone.

@tikimillie

3 ай бұрын

They’re obviously vampires in disguise

@SabbaticusRex

3 ай бұрын

@@tikimillie Bats can be super cute -- but they are _total_ dicks .

@sunninho

3 ай бұрын

Their biology and evolution allows them to withstand viruses that kill all others, including rabies. We must inherit their genes and become bats

The immune system may not be directly responsible for the longevity. He mentioned in the last 5 minutes that bats have better DNA validation. Just having that may lead to the longer life. DNA validation is the running theory on why elephants and whales live so long and lack cancer.

@AnnoyingNewsletters

3 ай бұрын

Validation helps us live better and longer. 😉

@cynthiagonzalez658

3 ай бұрын

Hypotheses need proof ‼️

@anim8torfiddler871

3 ай бұрын

Fascinating. Each passing day I am reminded of my GROWING ignorance. I would love to learn more about the concept of *DNA Validation.* Think I'll do a little browsing... Thanks to all for making the comments as good as the article.

@Angel-wo8gv

3 ай бұрын

We have very effective autophagy tho... problem is we eat way to often and way too much and pretty much never activate it.

@gregferguson7737

3 ай бұрын

​@Angel-wo8gv additionally mTOR ends up chronically switched ON due to cell senescence and cells fighting to offset sarcopenia which blocks autophagic activation. Rapamycin adminstered in intermittent doses might compensate for such in humans.

Now it makes sense why Batman sounds like he has a serious permanent throat infection, and never dies.

@vikassm

3 ай бұрын

This comment is underrated. Thumbs up 👍

@gilyun8352

3 ай бұрын

Its herpes

@darthregulus

3 ай бұрын

He ate out Cat Woman and got the clap in throat 😂😂😂😂

@gordslater

3 ай бұрын

me-ow chow

@kathyolney4083

3 ай бұрын

😂😂😂😂

I work under someone who has a doctorate in mammology/ecology and he specializes in bats, so I feel the need to correct some information on this video if you are interested in learning about bats. Firstly, bats are indeed as susceptible to disease as other animals. Currently they are more susceptible than other species and many of them are at risk of becoming extinct. White-Nose syndrome is a disease affecting all bat species caused by a fungus which was first seen in 2016. It has a mortality rate of over 90% and kills bats mostly by disrupting their hibernation, leading to them using vital fat reserves and dying of starvation. In severe cases it can cause them to be unable to breathe due to covering the rostrum or cause wing damage as the fungus actually penetrates tissues. Bats are not immortal, they are in severe risk if a cure isn't found. Secondly, the postulate that he is referring to with body size and lifespan is definitely something that we see a lot happen in biology, but as with anything else there are major exceptions to these patterns. The naked mole rat is the most extreme example I can think of because they can live up to 30 years, when compared to their most related extant cousins, all rodents which have lifespans of years in some species. Bats are very, very distant from rodents, they are closer to whales, all carnivores, giraffe, horse, etc than to us which all have lifespans similar to bats. We are closer to rodents than rodents are to bats. Phylogeny can be a better way to understand lifespans in animals because in most cases closely related species tend to have longer (K selected) lifespans or shorter (R selected) lifespans. Like anything though there are always exceptions that we don't understand.

@MrCazjd

3 ай бұрын

I have an idea, leave them alone??

@scottbrower9052

3 ай бұрын

He also doesn't address the wide range of bat species and sizes. Everything from tiny insectivores to giant fruit bats (a.k.a., flying foxes). Surely, lifespans will vary.

@promerops

3 ай бұрын

@@scottbrower9052 Are the insectivores and the fruit bat/flying foxes all that closely related?

@scottbrower9052

3 ай бұрын

@@promerops I don't think they are, no, but I'm not a zoologist.

@Dcupholder

3 ай бұрын

A man that lives to 80 which is the average life expectancy and has a normal heart rate of 80 beats per minute has approximately 3,36384 billion heart beats . A 150heart beats pm bat that lives to 40( *they hibernate that’s why 150 not 200/unusual for a bat, they live to 20 years tops) has 3,1536 billion heart beats

I know of two age records for bats, one (39) from Alberta, Canada, and the other (41) from Russia. It would be interesting to know if microbats from warm climates, that don't spend half their lives hibernating, are also of comparable length. Btw, the Alberta record was from a living wild bat that had been banded as an adult, so could be even older.

@HappyBeezerStudios

3 ай бұрын

small bats in hot climates would be even more affected by fever. Sure, the small body size means they would cool out faster, but the climate mitigates a lot of that.

@Arionid

Ай бұрын

would depend on their heart rate 💀

You missed the biology of birds. A rat who lives about 3 years has the same body weight and high metabolic rate as a pigeon. But the lifespan of pigeons is 35 years. And they tend to never look old. Instead of carnosine made in the liver from two amino acids, (beta-alanyl-L-histidine) as an endogenous anti-glycation agent, birds manufacture anserine, which is 7 times more powerful an anti-glycation agent as carnosine.

@EkilRevolution

3 ай бұрын

what is the anti-glycative mechanism?

@higherresolution4490

3 ай бұрын

The anti-glycation mechanism is defined by a biochemical pathway that you can find on Wikipedia or any biochemical website. There's no way to create that in the KZread comment section. Quite some years ago, Russian doctors created a treatment for cataracts, which represent glycated chrystalin proteins in the lens. In this case, they use acetyl-l-carnosine in a liquid form.

@Frrk

3 ай бұрын

The lifespan of pigeons in the wild is like 3-6 years. In captivity they do live longer, like 20 years

@higherresolution4490

3 ай бұрын

@@Frrk The lifespan of pigeons in the wild is complex. The shorter lifespan is partially a product of predation. The other factor is weather events, and also climate in general. 35 years is the maximum lifespan of a pigeon, and I can cite that fact.

Makes sense for an animal that lives in large colonies to evolve greater resistance to social contact diseases.

@ouknow1446

3 ай бұрын

Many herd animals are susceptible to social contact diseases.

@Alienami

3 ай бұрын

Especially an indoor moist environment of cooler temperatures, typically.

@ryandylan6946

2 ай бұрын

Yes it would make sense, buttt humans and a lot of other mammals have always lived in colonies without these great resistance. i think pure luck in the genetic lotterie is the reason

@Jack-he8jv

2 ай бұрын

@@ryandylan6946only relatively recently we started living in similar cesspit densities, even still, americas were wiped out by plagues that dont effect cesspit dwellers.

@policy8analyst

Ай бұрын

I hate mosquitos so I love bats.

I’ve always loved bats, and this cements my desire to help them.

@SabbaticusRex

3 ай бұрын

Ah-hah ! ..but a bat's pet pangolin caused Disease X . So , ya , bats are _total_ dicks .

@nerdjournal

3 ай бұрын

Fruit Bats are frigging cute. Like winged puppies.

@christophermullins7163

3 ай бұрын

​@@nerdjournal❤

@enigma9971

3 ай бұрын

Help them by not interfering. We think we help nature by interfering with it and we actually cause greater harm

@sneakydragon2352

3 ай бұрын

@@enigma9971 that's such an ignorant statement

My late father remembered seeing syphilis being treated with malaria at the psychiatric hospital where he worked in Sussex, maybe late 1950's or early 1960's

@dannydadog1987

2 ай бұрын

How did it work out and why particulary the psychiatric hospital?

@virtualtools_3021

2 ай бұрын

@@dannydadog1987It did work fairly often but fell out of favor because of safer alternatives like antibiotics that became avaliable. Possibly in the psychiatric hospital because advanced syphilis causes neurological symptoms

@robinac6897

Ай бұрын

St.Francis?

When this medicine is available there is 0 chance poor people get access

@jamesricker3997

15 күн бұрын

For a little while. Profit is a huge motivation

Bombing bats help to spread rabies rather than eliminate the threat to us. Before the bats were concentrated in one area, after the bomb those that survive fly off to new locations . Another reason why bats have special immune systems is that they range far and wide and come into contact with many more animal species. Since many live in large concentrations they need to be versatile in how they handle diseases.

@SabbaticusRex

3 ай бұрын

Very cool . Where did these bats go - asking for a friend . Ignore the bombs .

@lewischime5737

3 ай бұрын

​@@SabbaticusRexlol

@agaragar21

2 ай бұрын

So why isn't this the case for Humans who gather in large metropolis's like Tokyo ?........is it cause we're basically a new species, or our current environs are a new circumstance to our genetics

@nekhumonta

2 ай бұрын

​@@agaragar21humans have had to endure a lot of plagues since we started to live in cities, but we adapted by increasing our hygiene.

@bigheadrhino

17 күн бұрын

@@agaragar21out adaptations is what we can do with our brains. Hygiene like someone else said and medicine are examples of this. We are a communal species so we ven the fact that some of us die from disease is an adaptation because dying stops the disease from spreading.

There is another way of looking at this. Activity promotes circulation. Circulation aides the immune system. It isn't just the high body temperature but the circulating of the blood that aides the immune system. If I feel a bit down, like I may be coming down with something, I will go for a run, bike ride or hike. When I get back I feel 100% again. It is just movement promoting blood circulations which makes it easier for the immune system to do it's job. The only illness I've had in the past 35 years is disentery which I got from drinking hand squeezed lemonaide in Peru. In my defense, the beer there tastes like crap and I need a break from it. I should have gotten bottled soda. The point is that attempting to list a single thing as the sole reason for the bat's longevity and resistance to illness is a ignorant, at best.

@miguelmejia4656

3 ай бұрын

mic drop

@HappyBeezerStudios

3 ай бұрын

If it were just circulation, small animals would generally live longer. They have incredibly high heart rates and small bodies. But hey, the lemonade was bad but the beer was good? Just like in the middle ages. Just make sure to drink small beer or table beer if you don't want to get completely wasted.

@winoodlesnoodles1984

3 ай бұрын

@@HappyBeezerStudios 100% Which is why I stated "aides" the immune system. Good circulation with a poor immune system does jack squat. However, high body temperature from exercise, the added circulation from than exercise and a good immune system and you have a solid recipe to fight off an incredible number of diseases. That is not all diseases, because nothing other than death does that. 😁

@cykeok3525

3 ай бұрын

@@winoodlesnoodles1984 Your premise is contingent on the assumption that all other small mammals have a "poor immune system"?

@miguelmejia4656

3 ай бұрын

@@winoodlesnoodles1984 you also seem to forget other mammals make vitamin c in their body. so mammals don't really get sick as often. where humans don't make vitamin c and we have to consume it from nature and food.

Subscribed!! I love it. My interest in longevity biology naturally lead me into an interest in bats long before covid outbreak. What delight to see a basic summary of all I have read over many years into one short video. Thanks for making these facts about these remarkable creatures and the interplay between disease and the immune system widely available and more accessible to the public. You now have another regular viewer!

It's Morbin' time!! Loved this video! I did find it funny where you mention a study where they give bats ebola then immediately show a clip of a bat biting a gloved finger!

@superkd7030

3 ай бұрын

Zombie Apocalypse origin story right there. 😂😂😂

@michaelmeredith912

3 ай бұрын

Yep harmless…stick your finger in its mouth 😂

@danielasare5560

3 ай бұрын

😂😂 I’m sure it was pun intended

Imagine what would happen if we didn't have bats to do their job. Whatever niche they're into that requires them to be able to carry massive loads of illness, it's probably something we'd like to be kept in check by the bats.

@HappyBeezerStudios

3 ай бұрын

That's how I think about stinging nettles. Sure they might be annoying, but they're also vital for many species of butterflies, can be used as food and fabric making and make a mean aphid remover.

@Arionid

Ай бұрын

their niche is just nocturnal flier, replacing them with a bird would lower prevalence of the viruses they carry, in exchange for whatever diseases birds carry 💀

Bats are like mr. Burns. They have so many diseases that one ends up fighting another, thus leaving the host alone for living long. 😂😂😂

@paradisepipeco

10 күн бұрын

*_"To a rat, a bat is an angel."_* ~~ Bruce Wayne

Fever theory is kind of correct. The nightly fevers from flying hold the virus count at a low level. Thus giving the bat time to produce antibodies to said virus.

@rickwrites2612

3 ай бұрын

Hmm..except he does say they did have a high viral load, they just didn't get sick, and other mammals with similar fever got sick if they had low virus level...the serine vs leucine in immune system and targeted immune system seem more promising

@davidbatista1183

3 ай бұрын

Perhaps virus "hybernate" and therefore doesn't do damage ?? 🤔 Like bears that don't do anything during that state but instead of hybernating on extreme cold they do it on extreme hot 😆

@Bialy_1

3 ай бұрын

@@davidbatista1183 The video contains info about bats with extremely high amount of viruses that would literally be super deadly to other mammals and was not doing anything to bats... so there is no hibernation and there is huge resistance to what ever is killing other animals or the virus is not fully functional in them/cauing different reaction to some of his mechanisms).

@davidbatista1183

3 ай бұрын

@@Bialy_1 perhaps u misunderstood my comment ?? 🤔

@mnomadvfx

3 ай бұрын

@@Bialy_1 "so there is no hibernation and there is huge resistance to what ever is killing other animals or the virus is not fully functional in them/cauing different reaction to some of his mechanisms" Bats seem to have evolved into an ideal carrier (non infected host) species for a multitude of viruses. The ongoing hyperthermic action caused by their nocturnal flights may be the primary culprit for this ideal carrier phenomenon by the regular decimation of viral loads by way of thermal decomposition. The viral loads have the daytime to recover somewhat by division.

Theres actually a two stage immune response in humans when you think about. 1. Body temperature. 2. Indleness. In constrast, on serveral occasions when I start to feel sick and probably against better advice, I will go for a run. Specifically to get the blood flowing through my system as efficiently as possible, rather than stagnating. So perhaps two very different methodologies are at play. One hyper accelerates blood chemistry/temperature, while trying to keep disease transfer minimised, through low flow rates. One hyper accelerates both blood chemistry/temperature and efficiency/flowrate to kill disease as rapidly as possible, ignoring the transfer rate. Stasis vs hyperflow. Be interesting to see how fast the blood chemistry is in bats, if there is little to no serious inflammation. Perhaps this is done the opposite way around too. At least in relative terms. Preffering a high flow filtration system, might explain why there is few if any zombie cells in bats. Yet serious accumulation in humans. Perhaps the solution then, is to hyper accelerate/filter blood flow, rather than increase immune response aggressiveness and the resulting inflamation. Thus unfit people die early. Heart disease through blockages and/or reduced flow rates, with materials that arent flushed and accumulate in the system instead. Basically, we need to flush the turds from the blood, instead of being left with something that looks like a fatberg in a sewer.

@anim8torfiddler871

3 ай бұрын

It seems to be a VERY COMMON feature of pathogenic microbes to have a fatal sensitivity to excursions to a metabolic temperature regime that the Host can tolerate longer than the _bug._ I'm guessing the Fever response would NOT be so nearly universal if there were many more heat-tolerant microbes. Seems to suggest they evolved and spend a lot of time in colder environments.

@sneakydragon2352

3 ай бұрын

@@anim8torfiddler871 temperature isn't only an offensive weapon, it's also a support weapon, a lot of our defence mechanisms work better when in high temperatures, fevers don't usually get rid of a cold by themselves, fevers help our immune system work better. As for "evolved in colder environments" argument, not necessarily it's a lot easier to "resist" cold than it is to resist heat, as when a cell/virus is in a cold (sometimes freezing) environment, it slows down the production of proteins and remains inert for a long time, while if its exposed to heat/radiation it simply starts to die because the radiation/heat damages its internal structure and delicate protein-production mechanisms

@anim8torfiddler871

3 ай бұрын

@@sneakydragon2352 thanks for amplifying the information.

@ouknow1446

3 ай бұрын

In another words heat up which is why fevers are often a reaction to infection.

@zoeydeu2261

14 күн бұрын

In my family we do the opposite (not running). If a viral infection is taking place, we rest/sleep and sweat it out by covering ourselves with blankets to quickly increase the fever - up to a certain point, so it doesn't cause heatstroke/brain damage - to cook the virus. The rest is so the body can focus on fighting the infection, and sleep helps with recovery. If done early enough, we usually get well pretty fast.

Honest question 1:40 Is there any documented case of SARS-COV2 in wild bat population? Or any documented case of it jumping from bat to human? I remember hearing around year ago that there were none, which was giving more credibility to lab escape theory. Did something changed?

@Alyshakulta

3 ай бұрын

Everyone knows by now it was from the lab. We are just supposed to ignore it. Did you not get the memo?

@dankline9162

3 ай бұрын

Coronaviruses are just a type of respiratory virus (cold, flu) that bats can also carry. Cov2 was modified, it could of been taken from bats, but seems to have gained some functions with the help of man.

@gabek1381

3 ай бұрын

​@@dankline9162Similar corona viruses circulate in bats. Whether or not this one leaked from a lab, there is no evidence it was modified. So why don't we not spread unsubstantiated conspiracy theories.

@MrCazjd

3 ай бұрын

It’s an insilico-virus, a computer model… so no. They’ve never isolated it in anything and they admit that.

@superkd7030

3 ай бұрын

@Alyshakulta Yes, everyone knows it came from Fort Derricks, but not talking about it allows people to blame the Chinese for it. Just like Nordstream was an American job, but as long as we are all 🙈🙉🙊 we can blame the Russians for it. Cause these countries harming themselves on purpose makes totally sense. 🙄😒😒

Personally the most attractive feature in a bat as a mammal, is it ability to fly - anyone working on that?!? ;) Thanks as always for your great content.

@douglasbrenner1351

3 ай бұрын

I'm no expert, but I strongly feel the bats ability to fly is probably related to their possession of wings.

@tharusmc9177

3 ай бұрын

​@@douglasbrenner1351😆

@christophermullins7163

3 ай бұрын

​@douglasbrenner1351 😂 tyvm ily have a great week

@sneakydragon2352

3 ай бұрын

humans are too heavy for this, unless the wings are too long and it requires a full engine to create the energy to produce it, in that case we have airplanes and helicopters....

3:51 I was not aware organisms use POSIX operating systems! Systemd too! It makes sense though. The other OS would result in a blue screen of death immediately after birth and evolution would have eliminated it aeons ago.

@stevendorries

4 ай бұрын

Technically NT based Windows is POSIX compliant too, POSIX compliance doesn’t guarantee stability. See also, feinting goats who are clearly running XP Pro without any service packs

@ps.2

3 ай бұрын

Eh, neither sudo nor systemctl are POSIX commands. Maybe you meant to say Linux?

This seems like the beginning of a new school vampire flick where we try to extend our lives...but end up turning ourselves into vampires 😒😂

@mastergems5145

3 ай бұрын

That movie already exists where humans become almost extinct while people have become vampires

@josephharden5592

3 ай бұрын

@@mastergems5145 but was it based on this knowledge about the longevity of bats, humans trying to use that scientific knowledge and then inadvertently creating vampires?

@ynraider

3 ай бұрын

@@josephharden5592 "Morbius". It's the movie of all time... "It's Morbin' Time!"

@ynraider

3 ай бұрын

@@mastergems5145 "Daybreakers" is an instant classic!

@hemidas

3 ай бұрын

Daybreakers?

Super-interesting coverage! Thanks!🙏

Absolutely fascinatingly educational. Well done!

It makes sense bats 🦇 would live long, because they physically cannot maintain large broods due to weight concerns. That means in order to have a lot of offspring, they *need* to live long, thus creating a massive selection pressure to gain de-aging adaptations.

No wonder Ozzy is immune to everything.

@boke75

3 ай бұрын

Except maybe to brain damage. 😂

First vid from you and I'm already subscribing, good job doc 😉

Thank you Dr Ben for promoting Planet Wild. Their videos of collaborative land/habitat restoration Permaculture techniques and the subsequent successes are fantastic.

I thought it was from drinking blood and hibernating in a coffin

Cov from bats? Maybe pre bioengineering...

@tim_koch14

3 ай бұрын

Maybe he confused SARS-CoV and SARS-CoV-2. Not very probable though.

@dylaninnes8541

3 ай бұрын

Lol yup

@wolf-xf6hf

3 ай бұрын

Thats sars cov 2 not covid 19 two different viruses

@tim_koch14

3 ай бұрын

@@wolf-xf6hf Covid-19 is what they called the illness caused by SARS-CoV-2.

Awesome as always thanks ❤

9:27 IT'S DIANE GUERRERO! I didn't know she made stock videos and images back then, but it does make sense since she would only become and actress at 24 and she had to start from somewhere

2:17 was that Dracula: Dead and Loving it?

So that's why BATMAN doesn't age 😆

@n.henzler50

14 күн бұрын

Unless you count Dark Knight Returns, where he's 50 years old and looks 80. Given what he puts himself through, that's probably accurate.

Its MORBIN' TIME. Great vid, quite insightful.

Fascinating! So great to learn something completely new .

The same factors that allow bats to live to greater ages than similarly sized mammals like rats have the same effect in parrots and some other birds, there are a number of parrot-sized birds that live for around 40 years and much greater ages are claimed for some parrots but are difficult to verify. Small birds and mammals have a very rapid heart beat which doesn't seem to be related to their life span. I

Love the cute dogs to illustrate mammals 😂

Thanks for your work very simplified which is good for me. I think some of this work could cross over to auto immune conditions which also have this inflammation factors.

this video was just awesome instant subscribe

you'd think any cellular ability to inhibit dna changes due to high virus loads bats might have evolved, would also have the effect of making integrity of normal dna information and consequentially other cellular processes much more robust and hence likely less susceptible to the effects of aging too...

@ps.2

3 ай бұрын

Key word "evolved," though. Any mechanism that inhibits DNA damage _also inhibits evolution._ This is not always an evolutionary advantage.

@blengi

3 ай бұрын

@@ps.2 perhaps, but we know different tissue types can have different rates of mutation/viral introgression and therefore different tissues can be more of less robust in terms of dna alteration. Such that reasonably the robustness of most of the body versus gametes carrying forth the evolutionary variation doesn't have to be 100% in lock step. Surely there is a statisitical signature in the dna of whether this is the case, be interesting if anyone knows.

One theory says that having less predators increases the evolutionary advantages of staying fertile for longer and later in life which otherwise makes little sense given that it/he would die early anyways being catched by predators. Humans should have a much longer life span then we currently have but apparently War has replaced predators historically/anthropologically speaking

@jBiz91

4 ай бұрын

I recently watched a video on the biggest fence in Australia. The baby kangaroos on the side with less predators began to grow a lot slower than the kangaroos on the side with predators and I'm sure it said they was giving birth later in life. Also after world war 2 during the baby boom over 70% of births were male which has to be true otherwise I would have more than zero girlfriends 😂

@markmuller7962

4 ай бұрын

@@jBiz91 So interesting, yes it's very possible that the biology of pregnancy is heavily affected by what the mother see around her environment, actually I remember a documentary where it was scientifically confirmed on many traits of the child, the doc wasn't about gender ratio but other characteristics

@b.a.erlebacher1139

4 ай бұрын

​@@jBiz91Great story, but not true. As usual, about equal numbers of boys and girls were born after WWII. The only places you see a disproportionate number of boys to girls is places that allow people to select for sex by abortion or infanticide. China is an example.

@b.a.erlebacher1139

4 ай бұрын

Humans already have more than twice the lifespan of other mammals of the same size. You can see this in the charts shown in this video.

@jBiz91

4 ай бұрын

@@b.a.erlebacher1139 Spikes in the number of boys typically happen at the end of wars. This phenomenon has been dubbed the “returning soldier effect”. It can be seen after both world wars, when more babies were born and even more of them than usual were boys. Also human lifespan has doubled in the last 200 years thanks to mecidine, clean water and technology which other mammals don't have access to

Interesting video, loved the systemclt command 😅

Unfortunately, cancer is still a major health issue in 2024.😔 I hope research on bats could help us find real solutions.

Body temperature and metabolism usually go hand in hand, but it is body temperature rather than metabolism that is responsible for most aging, an experiment showed. When something does deviate, living much longer than it should, those are clues to extending life. Both bats and birds have some species living much longer than they should. They clearly have tricks. Living at a lower temperature is also an approach to living longer we see in naked mole rats, and bowhead whales. Lower temperature, of course, is no guarantee of longer life in a species. Almost all the longest lived species are much cooler, like Greenland sharks and 500-year-old mollusks. These live their lives in sub-zero temperatures. We are the temperature we are because our enzymes need a tight temperature range. Which is why we feel bad when our cores or brains are too hot or too cold. It will likely be possible to change this at some point to a lower temperature through genetic modification, though, that may have to be done early in development. It is virtually impossible to modify every cell in already complete organisms, and those cells that are not changed would likely die when exposed to cold temperatures. Combining protections seen in hot, long-lived species with lower temperature could extend life literally hundreds of years. Just cooling mice 1/2 degree extended their lives 10-20%. That said, there is no point of living longer if the brain slows down, but it feels like the same amount of time. So we may have to borrow more to speed up the brain and muscles so we are not sluggish like cold reptiles. I suspect adding some genes cephalopods have for brains might do the trick for brains. Octopuses have 168 protocadherin genes that code for brains, we have only around 80. Muscles might require genes from fish or sharks.

@JanaPersson

4 ай бұрын

I think it can not be only genetics that has this effect of longevity and effectively combating damage in the organism. It would seem that bats have access to an extended toolkit, and that its cells and organs are more effectively organized and geared towards general repair and countermeasure compared to other mammals. It would have been interesting if someone like Professor Michael Levin had made some sort of a study of bats, in light of his extensive research into bioelectrical communication among cells and tissue and their innate ability to adapt to novel circumstances and self organize.

@DevPythonUnity

3 ай бұрын

i dont think it all accurate, i have notice, and hard form manny people that when they exercie they feel much better, if they dont, they feel "rusty" body is in all kind of pains, it seams like, Exercie does some trick, i presume that:1. exerciese increases tempterature, 2 presume lactic acid and oxidacion can remove something from our bodis that is being generated if we dont move,,, its almost like, our bodids prodces something that is harmfull, but exercice can get rid of it

@ChessMasterNate

3 ай бұрын

@@JanaPersson That is genetics. "Innate" is synonymous with genetics. Your choices are: genetics, environment (includes diet/supplements/drugs, toxins, pathogens, symbiosis, air pressure, air composition, allergens, sounds, climate, disasters, radiation, predators, prey, relations with members of own species, and species which are not predators, competitors or prey in relation, care by parents or others, experience, other dangers), chance (likely a factor, as genetically identical mice in exactly the same conditions still live various amounts of time), and supernatural/alien intervention. Anything beyond genetics and environment, we have limited ability to address scientifically.

@ChessMasterNate

3 ай бұрын

@@DevPythonUnity The highest health over much of the lifespan does not necessarily mean it leads to the longest longevity on average. Also, it is the temperature you average over time that matters, not short periods of elevation or decline. I know sauna heats you up, but then you fall below baseline most of the rest of the time. I suspect exercise may have similar effects. But, yes, exercise is important, just that optimal amounts may not be the same for both health and longevity. And in fact, the people trying to optimize longevity such as Bryan Johnson and Michael Lustgarten intentionally do far less exercise than athletes would do as a result of following the results of blood tests. But they are still trying for very good body composition like an athlete.

@JanaPersson

3 ай бұрын

@@ChessMasterNate Yes, "genetics" is the standard answer to questions like these, of course it is. Which is why I suggested something a little different; a type of research that would potentially render a bit more information to illuminate an important subject with great potential in the area of regenerative medicine. The genome codes for the production of proteins. It contains no information about, for example, body plan. Where to put an eye. How long a limb should be. This competency arises in the cell and in clusters of cells and is expressed in the form of bioelectrical impulses and chemical compounds. Find a podcast interviewing Professor Michael Levin, you will be glad that you did. I'd recommend Lex Fridman's excellent podcast here on KZread.

There was human testing on hyperthermia as cure. The first subject died then the researchers learned to adjust the ph change in blood and increased head (brain cooling). It showed some cancer death and considerable virus death.

@wolf-xf6hf

3 ай бұрын

No fucking shot researchers just killed a dude

Great report!

If high body temp kills infections, how does it survive to spread with the bat as a vector?

Thumperfitz, Iben's wife, here. Thanks for the fabulous video!!! Ya' know, bat's wings are basically seriously webbed hands making them the best mammalian cheerleaders as every time they fly by, they give you 2 thumbs up, so Awesome or bats!!!!!

Great video Dr Ben Miles! Very informative and amazing! Seeing those cute bats makes me want one as a pet 😂 I live in Manitoba and a long time ago i heard that one way to help the environment is to buy/make a bat house to help bats live in the city since they are a cornerstone species. Would a slightly higher city population of bats increase the spread of diseases amongst animals and humans or is it such a low population of bats already that increasing it by 50% wouldnt change disease spread but would help nature with the other ways that diverse ecosystems benefit?

Very interesting. Looks like people are working hard to understand these bat benefits. It's rather impressive, that lifespan!

I just thought of a great movie idea. Researchers are trying to create life extending science for humans and create human vampires instead. 28 Days move over, 33 Nights is the new hotness.

Sadly, the only way to prevent and reduce habitat loss is to reduce or prevent the spread of humans.

@MrCazjd

3 ай бұрын

I blame pugs, dirt dogs 🤮

@pugowner1347

3 ай бұрын

@@MrCazjd Mainly people like you.

Can I just say I really appreciate the sudo systemctl command you put on screen. Nice!

@akostadinov

3 ай бұрын

yeah, I upvoted the video for this reason

@ayanned

3 ай бұрын

same

Dr ben miles what size can a bat get too for i seen a bat of epic proportions much bigger than i ever though possible at the sea shore and it was trying to drag my fish away lifted it and it was at least 3.5 kg what was it a new species or what ?

The easiest way to get rid of senescent cells is to learn about how to take Fisetin in the proper way for high absorption while also taking the amount that is a threshold dose to activate the natural clearing of senescent cells.

Is the miracle cream that comes from this called Benjamin Bat-on? Like Benjamin.. Button.. I'll show myself out

Ok now lets stop messing with bat viruses in military labs🤐🍻

@crocop2o12

Ай бұрын

No need to worry about that, they already made GX_P2V , the deadliest virus ever with 100% death rate, so if you hear about something like when sarscov2 started, it means they released it

@CS.AtheistChannel.VoteBidenAOC

28 күн бұрын

No way. Bats r cool

@DutchmanAmsterdam

11 күн бұрын

Too much money and power in it. Ask Fauci and Xi, although they tend to avoid honesty.

Well done, Thank you Side note: There are no more wide forests in the UK.

40C is not wildly deleterious for bacterial/viral pathogens. It however improves all elements of the mammalian immune response, from cellular response of macrophages to cytokine release. Optimum temperature for gut bacteria is about 37C Pathogens actually do better at about 40C, but use local resources at a greater rate, leaving them vulnerable to immune system action.

so they were looking for the fountain of youth, it escaped the lab and 2020-2023 we all got screwed over, loss of freedom etc.

@knivescom

3 ай бұрын

They were not looking for the fountain of youth. They were looking to kill us off.

Having a thumbnail with false information is among the fastest ways for a channel I've never seen to get put on the 'do not recommend channel' list.

Very interesting. Thank you.

I think it might be dangerous to use RNA(?) to turn off genes or tamper with the immune system. There might be risks involved for the patients if they become immunodeficient. Is there proof it won’t be carcinogenic?

My AI app is still convinced that all bats die of rabies. It's hard to find accurate info about what really happens, so this is very welcome and enlightening.

Extending the human life span will bring many other sets of problems across a wide spectrum.

@emjakos3548

3 ай бұрын

Every change comes with new kinds of trouble. We have already extended lifespans.

@kahlesjf

3 ай бұрын

@@emjakos3548 How many more people can the planet sustain? Now, considering that number, expand the lifespan of everyone on the planet. Or are you just talking about extending the lifespan of the monied elite?

Mice eat about 15 times a day, bats eat twice a day between dusk and dawn. Maybe the bat goes into Autophagy due to not eating. Autophagy is known to repair human cells.

thanks Dr. Jeurac

Rhetorical Question - Why do we humans always want to assume that longer liFe is better? There are 8 Billion of us, increasingly fewer of us have homes to live in, etc, etc. As a 73 y.o., I accept that fact of my eventual demise. I only ask to live healthy, for the days that I am here. If we manipulate our biological capacity for longer life - is that really a benefit?

That’s what we need tyrannical elites living decades longer 😂

Insect diet or fruit diet along with flight adaptations like birds is behind their longivity 😊

One fascinating additional issue, not addressed in this video: maximal metabolic capacity. Several years ago, a book, "Power, Sex and Suicide" by Mark Lane addressed a fascinating phenomenon, having to do with "excess" mitochondrial capacity. If you look at the weight vs. longevity graph, birds live much longer than "expected." A finch smaller than a mouse lives 30 years, and 3 lb. parrots can live 90. Turns out a trained endurance athlete can increase his/her metabolic rate with exercise by a factor of 2.5. A bird can do a lot more than 20. This "excess" reduces the generation of reactive oxidative chemicals that are detrimental to health and longevity. I wonder how bats do in terms of "mitochondrial reserve."

How does the immune response processes in bats relate to consuming 2000-5000 mg of lauric acid on a daily basis for humans? Assuming lauric acid or monolaurin creates an environment that makes it hard for infectious entities from building up in the body, then wouldn't this reduce the amount of inflammation entities in the body that are also destructive within the body? If so, then could using coconut oil, or lauric acid supplements, might help slow our own aging? Also, could the body's reaction to such infectious entities or other substances be a big part of the real reason for other conditions, like high cholesterol and similar things?

outstanding!

Great video

Looks like this’ll be an informative channel

Actually, sitting in a hot tub or sauna…or even a 45 minute hot shower that raises core temperature 1 to 1.5 degrees once a day is associated with better sleep, increased growth hormone secretion, and enzymes associated with autophagy.

Put the transcript of this video in Chat-GPT to summarize what he said into a minute video.

3:53 I high appreciate your Linux reference.

the part about fever killing or inhibiting the replication of pathogen is a misrepresentation of the function of fever. few specific pathogens have such strict temperature requirements that they get weakened by a mere fever. for most pathogens those temperatures help them strive and a rising internal temperature would send you into cardiac arrest long before it kills any pathogens. the actual role of fever is favor various immune functions, it increase the mobility, proliferation and effectiveness of several immune cells, such as leukocites and t cells.

haha, the linux sudo command insert was very funny! :)

Very interesting lead to something fantastic.

Hummingbird: hold my beer!

Wow, so Batty, the bat living the cave of my backyard will live longer than me. I love him❤ Every year I can't wait spring to see him again.

Fascinating.

Thanks. How (& in what form) was serine residue given to humans, & from where was it gotten? tavi.

Illuminating.

What if their resilience have to do with the way they sleep or because they do in the day time, or fully surrounded by air. They have been designed to have a warm blood at night when it is colder, and still be ok sleeping fully exposed in the day time when it is warmer. For heart rate is not the only specific trait of bats.

Bravo Dr Miles for this amazing video on bats, my favorite animal ever 🦇 most people fear them, but I love 💕 and thank them for their service to humanity!! They're bug killers and bring us order to our world 🌍 in ways that we don't understand!! Many also believe strongly that they are deadly disease 🦠 carriers, but I think not, so again I totally thank you for your valuable information on them and I hope that people will understand that bats 🦇 are our best friends and NOT OUR ENEMIES!!! 😊

What are those two studies that you mention at 11:03

Great video. Probably the most important and interesting one I've seen for a long time. I have been a medical doctor for 39 years. Stop doctors giving kids anti pyretics frequently. Thanks from Ireland.

Sadly we are obsessed with long age , but ageing is side effect of growing. Cells die , if not could cause more harm than good. Long age is directly related to environment & predation. Lesser predators means more age. Immortal jellyfish too are not immortal in real life. But slower metabolism is key to longevity. However it evolved in response to extinction event

So much for the Planet Fitness... "take it easy" workout model

Bats are awesome, I so wanted one as a pet when I was a child! Sadly I was never able to convince my parents this was a good idea 😂

Didn't expect to see a systemd reference in a video about bats, but I ain't mad 😸

Maybe by studying long distance runners we can shed more light on the effect of prolonged raised heartbeat and temperature on our own biology.

All these discoveries are great. Unfortunately we still lack many tools to achieve viable therapies. There is so much to discover! What a time to be young!

So what if its a click bait title... Look at all the internet know-it-alls. This man provided a lot of great knowledge and insight, Cant anyone just say thanks great video? THANKS DR BEN GREAT VIDEO.

Bat Outta Hell has a whole new meaning now. That's one hot ass mammal lol

Bats have ao many cool adaptations... I feel like there is lots of potential for a cool batfolk type thing in fantasy settings ot ttrpgs.