- How did Dr June's research with CAR-T cells began? 1:55
- Why was HIV ideal for this engineering T Cells? 6:29
- How is CAR-T cell therapy different from chemotherapy? 8:10
- Eureka moments of CAR-T cell therapy journey. 12:31
- Dr June's reunion with 40 children who were beyond help. 17:59
- Is there a target on all cancers & is it just a matter of finding it? 21:41
- Use of HIV vs CRISPR in CAR-T cell program. 30:21
- Why did some myeloma patients respond to CAR-T therapy? Myeloma cells lack CD19. 38:01
- Is it possible to build a CAR-T cell to recognise more than one antigen? 41:57
- BITE technology. 43:01
- CAR-T cell booster dose? 51:04
- Treatment for the newly diagnosed myeloma patients. 52:07
- Difference between CAR-T cell therapy & Provenge or Sipuleucel T used in Prostate Cancer. 55:06
- CAR-T cell therapy in AML and Colon Cancer. 58:18
FDA approval of the breakthrough CAR-T cell therapy for cancer brings the first approved gene therapy treatment to the United States. It reprograms the body's own immune system to recognize and kill cancer cells. The therapy initially called CAR-T cell immunotherapy and now named Kymriah by Novartis, is approved to treat children and young adults with a recurrent form of the blood cancer called acute lymphoblastic leukemia (ALL). Dr. Carl June of University of Pennsylvania, is one of the pioneers of CAR-T cell research and leads the team responsible for the historic FDA approval.
This talk has been created by CureTalks.com, a social initiative by TrialX to facilitate discussions for solutions, with a mission to heal the world through information and sharing of knowledge. At CureTalks we discuss a wide range of medical, health, and wellness issues, bringing together the doctors, researchers and patients on the same platform.
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