The Wittig Reaction

The Wittig reaction is one of the most important carbon-carbon double bond formation reactions that you're going to see in your course. So, in this video we'll go over this details of the reaction mechanism and what to look out for on the test.
00:00 Intro
01:18 Ylide formation
04:09 Reaction with the carbonyl
06:47 [2+2] mechanism
09:00 Types of ylides and stereochemistry
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Пікірлер: 11

  • @VictortheOrganicChemistryTutor
    @VictortheOrganicChemistryTutor4 ай бұрын

    Please, like, share, and comment to help promote this video! If you would like to support the channel, you can do so by either donating or becoming a member: Donate: www.organicchemistrytutor.com/donate/ Membership www.organicchemistrytutor.com/membership/

  • @varunarora1256
    @varunarora12564 ай бұрын

    Thanks for making this! You've made it quite clear and answered all the questions I had about this till now.

  • @Kelly-jh6dy
    @Kelly-jh6dy3 ай бұрын

    I just had my final this week. and I wanted to thank you for all your video. I literally just watched all these videos and ended up doing so well on the final. I hope you continue doing this. Thank you so much.

  • @VictortheOrganicChemistryTutor

    @VictortheOrganicChemistryTutor

    3 ай бұрын

    Wow, that's awesome! So happy to hear my videos helped you out. Good luck with your future finals and academic career!

  • @FiendishlySane
    @FiendishlySane4 ай бұрын

    Sir, could you please make a video on the abnormal riemer tiemann reaction or ciamician dennstedt rearrangement

  • @VictortheOrganicChemistryTutor

    @VictortheOrganicChemistryTutor

    4 ай бұрын

    Those are rather specific reactions which are not typically covered in an into organic chemistry course. I might make a video on those in the future, but not any time soon.

  • @JoaoPedroNogueiraBonesconto
    @JoaoPedroNogueiraBonesconto4 ай бұрын

    Great video, professor! Thank you so much. Would you happen to have any tips for experimentally doing a wittig reaction? I tried it with potassium tert-butoxide as the base, PPh3MeBr and a cyclohexanone analogue, but only got ~10% yield, and it only progressed with a large excess of base which lead to the formation of several aldol side-products.

  • @VictortheOrganicChemistryTutor

    @VictortheOrganicChemistryTutor

    4 ай бұрын

    tBuOK is not nearly strong enough to sufficiently deprotonate it. You need something much stronger, preferably BuLi which is easy to prepare if it’s not commercially available for you. If you don’t feel comfortable working with BuLi, you can use KH to deprotonate DMSO and use that as an effective base to yank that proton off your salt. When working with non-stabilized ylides, keep in mind, they are brightly colored (orange to red), so you’ll know you’ve made your ylide if your solution turns deep red.

  • @JoaoPedroNogueiraBonesconto

    @JoaoPedroNogueiraBonesconto

    4 ай бұрын

    Thank you so much, professor. Will do. One last thing, what good piece of literature on the reaction would you recommend studying? @@VictortheOrganicChemistryTutor

  • @peybak
    @peybak3 ай бұрын

    Shout out to the 30 year old yilde. His parents must be proud! Jokes aside, thanks for the video.

  • @VictortheOrganicChemistryTutor

    @VictortheOrganicChemistryTutor

    3 ай бұрын

    Glad you enjoyed the video!