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0:00 Intro
0:43 What are retinoids? How did they become so popular?
3:01 What do retinoids do? How do they work exactly?
3:37 Enzymatic conversions to retinoic acid (tretinoin)
5:18 Retinoid receptors (RARs and RXRs)
5:55 How retinoids empower skin cell regeneration
6:45 Epidermis and dermis
8:29 How retinoids empower better blood circulation to the skin
9:04 How retinoids boost collagen content in the skin
10:01 How retinoids treat acne
10:55 Retinal (retinaldehyde) is particularly good for acne
12:02 How retinoids treat hyperpigmentation
Retinoids are part of the Vitamin A family. They're well-known for their incredible benefits to our skin, making them a powerful tool in fighting aging, acne, and hyperpigmentation.
Did you know that retinoids also play a crucial role in many of our body's essential functions? From maintaining healthy vision to supporting embryonic development, retinoids truly are remarkable.
When taken orally, tretinoin, a type of retinoid, has been shown to be effective in treating leukemia. This is due to retinoids' remarkable ability to regulate cell growth cycles. So, not only do retinoids work wonders on our skin, but they're also vital for our overall health.
When it comes to skincare, tretinoin was the first retinoid to be approved by the FDA in 1971 for treating acne. You might know it by its brand name, Retin-A.
Here's an interesting tidbit: when people started using topical tretinoin for their acne, they began to notice improvements in their overall skin condition. This led to further research, and in 1995, the FDA approved tretinoin for treating sun-damaged, prematurely-aged skin.
Some other popular topical skincare retinoids you might be familiar with include retinol and retinaldehyde, often called retinal with an "A."
For those of you dealing with acne, you may have come across isotretinoin, also known as Accutane, adapalene (aka Differin), and tazarotene (aka Tazorac).
In this discussion, we'll be focusing on the popular anti-aging and anti-acne topical retinoids, specifically retinol, retinal, and tretinoin. Keep in mind that the terms retinoic acid and tretinoin can be used interchangeably.
This content is provided as part of our commitment to bringing science-based information to the public, and it is intended to offer general scientific background on the topic. However, health is complex, and individual cases can vary significantly. We strongly encourage you to consult with a healthcare provider who can diagnose and prescribe treatments specifically tailored to your needs.