The First Full-Size 3D Print of a Human Heart Is Here
Ғылым және технология
Imagine having the option to get a 3D-printed organ. Well, a team of biomedical engineers from Carnegie Mellon University has just developed the first flexible, full-size, 3D-print of a human heart, bringing us one step closer to that reality.
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Additive manufacturing printers are popular, but are typically known to build hard objects using materials like plastic or metal. But rigid plastic organs aren’t very practical. These printers could be used with softer materials, like biological hydrogels -- you know, to make a heart -- but those tend to collapse mid-print. But this new method can change the game.The 3D-printing technique is called Freeform Reversible Embedding of Suspended Hydrogels or FRESH.
It can print biological structures with soft squishy materials like alginate, a biomaterial made from seaweed, which feels like human tissue. AND it cleverly solves that collapsing problem during print by suspending flexible materials inside a container of gelatin.
For this team of researchers it all starts with a MRI scan from a real heart. The scan gets “chopped-up” digitally into horizontal slices by a program which then translates them into code that a printer will understand. A needle-like nozzle moves through the gelatin support bath, extruding thin layers of alginate. The layers stack on top of each other to build the shape. When the print is complete, it’s put in an incubator overnight, where the temperature is raised to 37°C to gently melt away the gelatin support structure, leaving only the 3D-printed heart.
#3dprinting human heart #health #technology #science #seeker #elements
Read More:
3D bioprinted heart provides new tool for surgeons
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"Adam Feinberg and his team have created the first full-size 3D bioprinted human heart model using their Freeform Reversible Embedding of Suspended Hydrogels (FRESH) technique."
The future of bioprinting: A new frontier in regenerative healthcare
www.medicaldevice-network.com...
"Printing body parts may well be the next step in organ transplantation - harvesting stem cells from a transplant recipient and printing them into a replacement organ could help bypass complications associated with organ transplant such as long waits for a suitable donor or immune rejection of the new organ."
Bringing A ‘Ghost Heart’ To Life
www.sciencefriday.com/segment...
"The human heart is one of the most complicated organs in our body. The heart is, in a way, like a machine-the muscular organ pumping about 2,000 gallons of blood in an adult human every day. But can we construct a heart in the lab?"
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Пікірлер: 669
Last Christmas gonna hit different once people have 3d printed hearts to actually give and take away
@calebjaymes9710
3 жыл бұрын
I want lungs
@rockybhaikusalaampodu4125
2 жыл бұрын
I want lungs , heart , kidney , Everything Lol 🤣
@haxozr
Жыл бұрын
Last Christmas, I gave you my heart….
@kairon156
Жыл бұрын
I would like dental implants myself but I could use a heart replacement.
We should also print brains for people who comment “first”
@triptisharmaaa
3 жыл бұрын
😂😂😂
@thealtruistmc5020
3 жыл бұрын
there is a 1st comment ryt below urs
@Clear_Prodigy
3 жыл бұрын
Every bloody video has an idiot commenting first or the year like we care!!! 🤬😂
@ChrisHarmon1
3 жыл бұрын
Second
@agent-33
3 жыл бұрын
Also for people who type in something that was already said in the video, and those pple who ask if anyone still listening in ?
As someone with heart problems. This fills me with hope.
@itsneverlupus5544
Жыл бұрын
How are you?
@ASNEGI
7 ай бұрын
@@itsneverlupus5544good, how about you?
Becoming a Bionic Commando seems like a reality now.
@danielcisa107
3 жыл бұрын
Stop playing cyber'bug'
@magnolia2
3 жыл бұрын
Just don’t wear undies and you’re halfway there!
@NarattoRadians
3 жыл бұрын
@@danielcisa107 Sorry to hear you have a playststion.
@bayraktarx1386
3 жыл бұрын
It's just a rubber model... 😂
@iusetolovehim8
3 жыл бұрын
jpnewpic88.men
Teacher: you must help people with a real heart People with 3D printed hearts:
@goofybutserious4807
2 жыл бұрын
?
This is what got me interested in biomechanical engineering about 7 years ago for college when the process was in its infancy, I hope I can one day make a contribution to the field and help save lives. Bravo this is what I love to see.
Haha. She thought she'd have the last laugh when she broke my heart 🙂....
@waywardvoid
3 жыл бұрын
Well, you had to replace it...
@Xyza.
3 жыл бұрын
Heartbreaking to hear
@Mark-sr3jw
3 жыл бұрын
Awww
"you might be willing to pay any price" You know someone is from 'Murican when...
@LUCTIANITO
3 жыл бұрын
Once I heard an american saying "dying is cheap and easy, advanced brain cirgury is not". Not gonna say he is wrong but profit shouldn't be the focus of the medicine industry, although it's an industry.
@bluegleam8168
3 жыл бұрын
@@LUCTIANITO surgery*
@reidkrupps3597
3 жыл бұрын
@@LUCTIANITO well I mean, when someone spends a decade or more in university honing and learning a highly advanced, very difficult, rare and sought after craft, works in an area that has machines worth tens of thousands, hundreds of thousands, or millions of dollars, and eluded to facility has the hire engineers to perform maintenance on regularly, costs become substantial. Now, the United States is a VERY large landmass with a very spread out population and has to have a very large number of such facilities employing prior mentioned personnel, so it wouldn't be hard to assume that someone would be paying for the facility, specific action, procedures or substance, along with the equipment needed, yes? Universal government provided health care and insurance if scaled to individual facilities on a plus end and mandatory value evaluated and to be provided as a minimum on the minor end would cost the US government horribly if it wants to maintain peak care of advanced facilities and to increase care in those to which are negatively aberrant. It can't without cutting costs. And most countries even with a smaller population and more importantly a smaller landmass (which effects the total number of facilities in most or certain circumstances) can't keep up as well, which is why a term know such as "brain drain" exists, and why the United States receives so many migrants of high vocational background
@infinidominion
3 жыл бұрын
@@LUCTIANITO you just cursed your own existence with that bs spelling of surgery😂😂😂😂😂😂😂😂🤦♂️
@MadChrisp
3 жыл бұрын
@@reidkrupps3597 of course it would be costly. But the simple fact that we are choosing between lives and cost is ridiculous. No expense should be "too high" to guarantee your citizens decent Healthcare. Expecially considering the budget we use on military and foreign spending.
Best part is this may end or at least reduce illegal organ trade
@Darkmattermonkey77
3 жыл бұрын
True. The illegal heart thefts have been steadily rising the last few years.
@jmatt98
3 жыл бұрын
@@Darkmattermonkey77 yep. You can pick from a menu in China
@andreaam805
3 жыл бұрын
There isn’t illegal organ trade 🤣
@thegrumpypanda1016
3 жыл бұрын
@@andreaam805 love idk what world u living in but yes there is.
@rockybhaikusalaampodu4125
2 жыл бұрын
I'll be immortal 🤣
My step father literally arrived home an hour ago after 3 weeks in hospital and needs to go back for the stent shown here in about a month. Talk about timing. Merry Xmas.
@m1thras
3 жыл бұрын
I hope all goes well. Merry Christmas.
I could see a hybrid...maybe a heart built with collagen but with electronics to mimic the heart's function
@Aetohatir
3 жыл бұрын
That's probably not what is going to happen. The printed heart would probably used as a sort of scaffold to then culture muscle cells onto
@Geomaverick124
3 жыл бұрын
@@Aetohatir anything is possible...especially if we start moving to a more bio cybernetic culture
@megamanx466
3 жыл бұрын
@@Geomaverick124 Indeed. Muscles have to be trained and heart cells are one of the earliest cells created/differentiated in a fetus. So I see what you're suggesting as perhaps the early version or a way to exercise/train the cells, because a weak heart wouldn't help much as a transplant. 😅
@gamberofritto
3 жыл бұрын
Somebody got an artificial heart
@megamanx466
3 жыл бұрын
@@gamberofritto Jean Luc Picard. 😆
Shame that there's a legal option now *throws away extra hearts*
@badhrihari1705
3 жыл бұрын
@Sir 4k would u like one sir?
@waynepooley6950
3 жыл бұрын
Barry Harry 216 I’ll take two. Do you have sesame seed buns?
@badhrihari1705
3 жыл бұрын
@@waynepooley6950 sure, you also get an extra heart for free
@magnolia2
3 жыл бұрын
Got any brains? My pet zombies are hungry.
@badhrihari1705
3 жыл бұрын
@@magnolia2 yes, take them before 3d printed brains flood the market Plus the zombies deserve 100% geniune brains
Dude, pharmacology is going to be set up in the coming years. Gene editing, Quantum computing, 3D Printed organs with organic similarities. Jeez what am I going to ingest years from now?
@nuterra9143
2 жыл бұрын
Crispr body manipulating pills. I am guessing in 15 years.
Immune system- "I'm about to end this whole molds career."
@sethdrake7551
3 жыл бұрын
the 3d printed heart: "im you"
@valikillsthecrew3782
3 жыл бұрын
Lmao
@godlikemachine645
3 жыл бұрын
It'll probably be printed from your own stem cells, so that shouldn't necessarily be a problem.
@andreabarrett878
3 жыл бұрын
@@godlikemachine645 You're talking fantasy sci fi which doesn't exist (& scientists who've tried for 50 years have gotten not far in achieving)! Shutting down conversations about reality of transplant complexity by 'solving' issues with fiction prevents actual progress based on a cultural investment in there still being a problem.
@godlikemachine645
3 жыл бұрын
@@andreabarrett878 bruh. Did you even watch this video?
"fresh hearts" is an uncomfortable phrase...
@danielcisa107
3 жыл бұрын
Look darling, i ain't gonna chopping hearts in the field all day Just for You to show up complaining about Bad marketing campaign names...
@hanavesela5884
3 жыл бұрын
I like the name it’s great especially if they advertise during the Valentine’s Day 😝
@waywardvoid
3 жыл бұрын
Depends how you grew up
@TheGeckoNinja
3 жыл бұрын
just go to china they have plenty
@Zing123_
3 жыл бұрын
100th like
4:36 Her face cracks me up! You know that she knows that we know that was a lame joke and I love it. 😆
Feeling heaviness in my Heart while seeing this video. Anyone else felt same like me ?
That is amazing. Great job, Carnegie Mellon University!
1 year later: First human skin made by 3d printer
@aportfolio8324
3 жыл бұрын
BRO! ITS ALREADY HERE! The made synthetic skin like 3 years ago.
@SickOfDemocracy
3 жыл бұрын
3D printing Dong is where its at bois. Those small PP dudes/bros will be on it at the very first commercial opportunity.
@jbhann
3 жыл бұрын
That would be great for burn victims.
@gregorymalchuk272
3 жыл бұрын
@@SickOfDemocracy I want 3D printed foreskins for boys and men.
As a manufacturing and design student I see this a great breakthrough but as for a side project this is extremely expensive 😅
IM GOING TO LIVE FOREVER!
@hufopi7286
3 жыл бұрын
You can say living forever is curse not a bless
@phantom66games45
3 жыл бұрын
@@hufopi7286 not if you can play videogames everyday
@naveenk8687
3 жыл бұрын
Lol
@jimppa159
3 жыл бұрын
@@phantom66games45 they will get borign
@SickOfDemocracy
3 жыл бұрын
@@jimppa159 nah. It won't. Been gaming for more than 20 years and it ain't getting boring.
This is a major step toward the ultimate goal of life. Great job humans!!
Ha! No one will be calling me heartless ever again! Victory is mine!
@nedya5358
3 жыл бұрын
Lmao
@Ghost-hs6qq
3 жыл бұрын
Damm that is cold
Surviving next 50 years would let anyone see so many awesome things like these.
So this seems like it's just a kind of scaffolding for an organ at this point. How does this compare with growing organs from stem cells in terms of which tech is closer to getting a usable organ?
@megamanx466
3 жыл бұрын
I think the Stem Cells are rather easy to acquire, whereas the natural scaffolding isn't. So they're working on 3D-printed versions. The vessels and nerves would still need to be worked out also. 😅
@10-OSwords
3 жыл бұрын
@@megamanx466 Hmm, so maybe they use this to put stem cells into instead of fully growing an organ on it's own, which I've heard they can only make small versions of. It's all quite confusing to me but interesting.
@megamanx466
3 жыл бұрын
@@10-OSwords Well heart cells know to beat and will do so when simply touching another heart cells, but they don't know how the whole heart's shape is or how to pump. Researchers found this out after learning how to create stem cells(perhaps before with embryonic stem cells) and so then started down the path of creating a biological scaffold as a frame to "build" a heart on. 😅
@joeblack9082
3 жыл бұрын
I remember the problem with 3-d printed stem cell structures is cells don't stay in the structure form. Until they can figure out that piece of the puzzle I don't see 3-d printed organs in the near future, or until we get quantum computing......😅. Excuse my grammar. O j juice mane 50 bricks youtube😆
that story touched my heart
I love y’all channel please never stop making video 💕💕💕 nobody has these types of video. You guys talk about interesting topics and realistic things as well. It’s a great blend. I’m always learning something new from you guys
@ShivamSingh-zj5tm
Жыл бұрын
Never give up
Thamk you seeker for bringing amazing new science discoveries and innovations to my attention!
I've had one shoulder and a knee replaced, the other shoulder is next summer....this is interesting in what could be done in the future!
So all they have to do is make it out of, or at the least just line it with, a conductive material or fiber that allows for contraction and relaxation and there you go, beating heart! Can't wait to see where this tech goes in the next couple decades!
This is so amazing! Your videos always make my day! Thank you Seeker!
@Mf-jg3hs
2 жыл бұрын
:0)
Crazy to see this now. I remember watching a thing on TV about 3d printed organs back in 2006.
Thank you Amanda. Merry Christmas to you.
Technology and innovation is moving so fast.
@bayraktarx1386
3 жыл бұрын
Yeah printing model of heart is real innovation!
Well here it is! Congratulations 🍾
In West Philadelphia born and raised in the laboratory is where I spent most of my days
Thanks for the video! Love your channel Excited for developments of the tech. Stay safe. 😁🎄🎁
We’re in the beginning of a complete new era in human history.
These scientists really seem heart at work!
A cool thing you can do is use hard plastic material to create a rigid structure and then use bioplastics to make a flexible material like building your leg you can use the hard plastic as the foot base in the rigid structures and then use the bioplastic for the knee joint ankle and everything else getting one big piece
So Amazing !
Mr burns: excellent
A similar approach was taken by researchers in Toronto a few years ago, to 3D print organs with stem cells, I believe
That's fantastic.
I love how we humans are evolving
Amazing!
This is an incredibly important step but its also as close to having a 3d printed replacement organ as inventing the wheel is to having a race car. It still has a LONG ways to go.
A great start! 😊❤👍🏻
Now we need only keep our brains fresh and we can live biologically forever
In 2168, there will be 'full-size 3D print of a human body' Another edit: fully functional with working organs Another edit: I love drawing Another edit: I display my art drawings on youtube
@YouPube_X
3 жыл бұрын
Prob 2068
@arcvyndyraxa
3 жыл бұрын
𝚒𝚝'𝚜 𝚌𝚢𝚋𝚎𝚛𝚙𝚞𝚗𝚔 𝟸𝟶𝟽𝟽 𝚊𝚞𝚐𝚖𝚎𝚗𝚝𝚊𝚝𝚒𝚘𝚗𝚜 𝚏𝚒𝚛𝚜𝚝
@kumarthecowboy
3 жыл бұрын
Black mirror episode in reslity
@nityanandsarkar8054
3 жыл бұрын
2050
@infinidominion
3 жыл бұрын
They need to print some personality
so with this can we implant an electric device and make the heart pumping artificially ??
@jonathans1759
3 жыл бұрын
Unfortunately not. Needs to be human cells or a lattice/scaffold that can support them. There has been a successful growing of cardiac cells that spontaneous beat but it's very early stages of the technology.
This is must needed for eye 🙂🙂
Worth funding🙂
the method of printing is pretty FRESH.
Can we have more construction and sustainable city/ smart city videos? Please and thank you for all your hard work
Amazing
Awesome vid Amanda
It'll happen, one day we will have the means to insert cells and simply wait and we'll end up with a heart, a heart with vessels and arteries, continueing to grow outward after the hearts grown, we'd probably just snip off the excess arteries and structures that grew at crucial points, swap the heart out and use those same cells around the suture points to allow to regrowth of tissue instead of leaving scars. Probably not like that but it'll be done. I'll be long dead before then.
Oh you nailed that last joke....... lol
Hope you win the HEARTS 💕...
Nice video.
Wow! Hopefully this can be used for organ transplants soon! We're really entering science fiction territory here...
Bio printing real human skin on a metal endo-skeleton will soon be possible. Real-life terminators is not a matter of if, but a matter of when.
Please do a video on the latest advances on 3D printed knees and other joints.
Life expectancy is now 5000 years lol
Isn't there already a thing like this? Where they make the template and the use the persons actual heart cells and stem cells to grow the organ
@megamanx466
3 жыл бұрын
I believe it was in the works, but this seems to be the cheaper & better version/design. 😅
Christina Yang finally made History with her research...
this is heart-tastic news!
I think it will be more important when we figure out cryogenics. Ability to 3d print cells that would flash freeze in place and be able to combine after thawing. Majority of organs could be replaced, only nerve system remains challenge.
Check out the company Organogenesis, they’ve got a patent and FDA approval for stem cell plasters or ‘bandaids’
Imma need a new heart in a couple years. Get on it!
What about the moving parts like the tricuspid valve? I had a heart infection this summer with damage to my valve and that thing is just 2 tiny flaps that regulates blood flow in only one direction your entire life. Can these 3-D printed hearts do all that?
@Ahmed_M7
Жыл бұрын
They can’t yet.
I get Repo Men vibes with this video 🥺
@jakejonesy9275
3 жыл бұрын
Oh I forgot about that 🤣
@megamanx466
3 жыл бұрын
I get Scavenger vibes with this video. 😏
I wish we could see more medical technology videos. Also diamond batteries
If the gel can support itself you can print from multiple angles, 🧠💥
Now girls can break my hear several times 😃
love it
I hope they can print brains...
Hmmmm, a "FRESH heart", does have a certain ring to it :O
Immortality
YES!
Wow!!!
funny fact, back in 2005ish ive read about 3D printed organs in popular mechanics magazine, I think at barn and nobles store?!, and it had a time when will it will it be a reality, I think it predicted 2025. I told people about it, they looked at me like am crazy, back then.
We've been working on 3d printing organs for at least 8 years
“My heart is in the work” -Andrew Carnegie
A human or animal heart isn't only a bunch of organic material in a particular shape and consistency. It's a set of specialized cells that can contract and expand to actually pump the blood. It's not yet clear to me how these 3D-printed models are going to achieve that.
@megamanx466
3 жыл бұрын
They(these 3D-printed models) are simply the scaffolding that the other parts of the heart adhere to. It's basically one of the final steps in the process to grow a fully functioning heart from "scratch". 😅
She's still gonna break it bro😓
Can you please cover the new aptera. That's a cool new innovation.
aight I'm gonna be on the watch for someone on yt to make a flesh light out of this
Feels like human flesh? Hmmmm gonna tell my investors at YouHub
everytime Seeker uploads me: *pog*
Cant wait to download someone's heart
Looks like giant gummy bear 😂🐻
I could use a new pair of kidneys. Is it capable of producing any kind of organ?
Cant wait to see this on thingiverse :P
Printing with live stem cells that will then become active heart cells...
Thank Yo
Go go gadget heart!
I would really love a new printed heart please ! Let’s hurry I’m almost 50 and really need new parts 🙏🙏🙏
Everybody gangsta, till the scientists made a human body