Resting membrane potential - definition, examples

What is the resting membrane potential? The cell's resting membrane potential is the electric potential of the cell, and exists as a result of ions moving into and out of the cell. This video covers the definition of resting membrane potential, as well as how to calculate it using the Nernst equation. Find our full video library only on Osmosis: osms.it/more.
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Пікірлер: 185

  • @RealSSTELLA
    @RealSSTELLA3 жыл бұрын

    best video I've seen on ionic basis of resting potentials! thank you, I've been searching and this one is the easiest to follow along and explains the equations/gradients the best

  • @eunahjew643
    @eunahjew6434 жыл бұрын

    This is amazing!! I'm have zero intuition for biophysiology but you made it as clear as glass. Thanks for breaking it down into baby steps!! Love your simple but comprehensive diagrams.

  • @charlessantosti
    @charlessantosti7 жыл бұрын

    Great, I had been waiting on Physiology from Osmosis for a long time! Thank you!

  • @mauriciosujo1999
    @mauriciosujo19997 жыл бұрын

    Wow, you make everything SO simple. i was stuck on a couple concepts here, clear 100%!

  • @l883l
    @l883l7 жыл бұрын

    osmosis! this video is brilliant !! I've read about this topic from endless sources but I've never felt until now that I've truly grasped the concept. Thank you so much for your work. I've watched at least 90% of your pathology videos and honestly After Robbins and Porth you have made my life so much easier! thank you

  • @osmosis

    @osmosis

    7 жыл бұрын

    Thanks so much! It would be awesome if you and your friends could review us on our Facebook page. facebook.com/pg/OsmoseIt

  • @ahlamalghamdi9303
    @ahlamalghamdi93036 жыл бұрын

    wow!!! super clear, feel so good watching this!!

  • @LittleBear2007
    @LittleBear20074 жыл бұрын

    I find your Osmosis is so clear and easy to remember. I want to be a part of your osmosis. Can't i?

  • @dimemo2023
    @dimemo20235 жыл бұрын

    You made it quite clear! Thanks!

  • @raghadalomari4058
    @raghadalomari40586 жыл бұрын

    this is the second time for me watching this, just wanted to say THANK YOU!!!

  • @EducatorSharmin
    @EducatorSharmin6 жыл бұрын

    Its really great understand! Thanks for making awesome video.

  • @annamarierosicka3845
    @annamarierosicka38456 жыл бұрын

    Thank you, this was VERY helpful! ^_^ Loved it.

  • @needmefeedme
    @needmefeedme7 жыл бұрын

    Clear as crystal, thanks!

  • @ilaila3504
    @ilaila3504 Жыл бұрын

    This video seemed so simple, I was brand new to this formula a couple of weeks ago. So I kept watching it, but once i slowed the speed right down - then it started kicking in! thank you so much!

  • @osmosis

    @osmosis

    Жыл бұрын

    Most welcome! 😊

  • @SummedUp
    @SummedUp6 жыл бұрын

    That was a great piece of work!

  • @gunnerprinceton9726

    @gunnerprinceton9726

    3 жыл бұрын

    pro trick : watch series on flixzone. I've been using them for watching all kinds of movies these days.

  • @arthurwesley7444

    @arthurwesley7444

    3 жыл бұрын

    @Gunner Princeton Yea, have been using flixzone} for since november myself :D

  • @judahcallum8504

    @judahcallum8504

    3 жыл бұрын

    @Gunner Princeton yea, I've been watching on flixzone} for since december myself :)

  • @user-ul9pv8fu2i
    @user-ul9pv8fu2i5 жыл бұрын

    Thank you this is soo helpful

  • @hg77777
    @hg777774 жыл бұрын

    Great video ! thank you again Osmosis

  • @ozzyfromspace
    @ozzyfromspace3 жыл бұрын

    This was really well done!

  • @bsnl230
    @bsnl2307 жыл бұрын

    Very good explanation, keep posting videos like this :D

  • @mustafadonmez7595
    @mustafadonmez75957 жыл бұрын

    woww you start physio, Thank of billions...

  • @asdssa2714
    @asdssa27144 жыл бұрын

    Really amazing ........iam really appreciate your great and fruitful work....thanks🙏

  • @_lia7245
    @_lia72455 жыл бұрын

    It is the nicest video i've ever watched !! Thank u :*)

  • @krupeshprajapati9332
    @krupeshprajapati93324 жыл бұрын

    Unexplainable!!! Unbelievable!!! Thanks🤗🤗🤗

  • @AbcdEfg-yj9vv
    @AbcdEfg-yj9vv7 ай бұрын

    Only video across globe that clearly explains resting membrane potential and equilibrium potential. Thank you sir 😊

  • @osmosis

    @osmosis

    7 ай бұрын

    Happy to help 💖

  • @nailaahli4262
    @nailaahli42627 жыл бұрын

    that was useful thankyou please do more physiology videos I'll be grateful for that

  • @Jen_nyy13
    @Jen_nyy134 жыл бұрын

    Very helpful thank you! Its hard teaching yourself this when you are taking online classes because of this quarentine

  • @shashankpahariya

    @shashankpahariya

    4 жыл бұрын

    Hii

  • @nehakakde3785
    @nehakakde37856 жыл бұрын

    I lkie the way he explains and the presentation is always very nice to watch n clear .

  • @osmosis

    @osmosis

    6 жыл бұрын

    Thanks, Neha! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J

  • @aoifewest
    @aoifewest6 жыл бұрын

    for the first time i understood. thank you.

  • @jaemineatschilli
    @jaemineatschilli2 жыл бұрын

    thank you for this clear explanation!! i have subscribed to your channel and will definitely explore more!!!

  • @osmosis

    @osmosis

    2 жыл бұрын

    Hi Tengku! Glad you enjoy our video! Hope you'll like our other videos too! ❤️

  • @thecrazygirlxo1347
    @thecrazygirlxo13476 жыл бұрын

    very helpful ! thank u

  • @leticiacavalcante2591
    @leticiacavalcante25917 жыл бұрын

    Woow!! Thank you so much for this video!! Awsome explanation

  • @osmosis

    @osmosis

    7 жыл бұрын

    Thank you, Leticia! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J

  • @firaolhabtamu703
    @firaolhabtamu7032 жыл бұрын

    Thanks you saved me a lot of time.

  • @TraumaticQue9
    @TraumaticQue94 жыл бұрын

    Thank you so much, I wish I found this prior to the test. I would have got these answers right. Damn>

  • @erikplumeda1299
    @erikplumeda12994 жыл бұрын

    This helped SO MUCH, especially during COVD-19 where learning things on your own from the university is a bit more difficult to understand on your own, when someone is not lecturing these bulky ideas to you. Great Video!

  • @nzzuraki991

    @nzzuraki991

    4 жыл бұрын

    Erik Plumeda so true

  • @avapilsen
    @avapilsen5 жыл бұрын

    this was so clear and helpful. thank you!

  • @borislavangelov3693
    @borislavangelov36937 жыл бұрын

    Great physiology

  • @lebenslangerschicksalsscha6690
    @lebenslangerschicksalsscha66906 жыл бұрын

    So good. Thanx a lot!

  • @jorgemerrengallegos5079
    @jorgemerrengallegos50794 жыл бұрын

    THANK YOU. Explained it really well mate!

  • @andrejmaric5955
    @andrejmaric59557 жыл бұрын

    Physiology! Great!

  • @yousifalhadithi1964
    @yousifalhadithi19646 жыл бұрын

    i never understood the resting memb. potential but now ... i still don't understand it

  • @samiras6962

    @samiras6962

    5 жыл бұрын

    mohammed just memorize it 🤷🏽‍♀️

  • @Apratim98

    @Apratim98

    5 жыл бұрын

    I know its fucking confusing, bcoz no one is starting it frm the basic, i have made video too on the same topic, watch it once i hope it will help you..and pls comment if it does..or any doubt..

  • @rania7801

    @rania7801

    5 жыл бұрын

    @@Apratim98 Thank you! I just checked out your video and it was really helpful! Thankfully I checked the replies.

  • @sabett198x

    @sabett198x

    5 жыл бұрын

    Lol, We are on the same boat Mohammed... and I can’t memorize something that I don’t have a basic understanding of...

  • @aleidaortiz4599

    @aleidaortiz4599

    4 жыл бұрын

    Me too

  • @sunshinetoday7
    @sunshinetoday72 жыл бұрын

    excellent, excellent video! I was wondering though, why was the calcium +2 intracellular concentration was not 0.0001? in the video it is listed as 0.001

  • @wen4768
    @wen47684 жыл бұрын

    Awesome content and i like it so much :DDD

  • @shitviksen
    @shitviksen Жыл бұрын

    This video is amazing. I am studying bilogical psychology, and the book didnt give me a clear picture of what this process looked like. Amazing stuff!

  • @osmosis

    @osmosis

    Жыл бұрын

    Wow, thanks for the feedback! 💕

  • @Abrar-gi9dn
    @Abrar-gi9dn3 ай бұрын

    THANK YOU!

  • @brentgroen3204
    @brentgroen32045 ай бұрын

    this is so great, the book i used just glances over most of this to jump to the action potentail. and i was struggeling to understand how the consentration and charges worked.

  • @osmosis

    @osmosis

    5 ай бұрын

    Thanks! 🙏🏼

  • @irispanagoulopoulou
    @irispanagoulopoulouАй бұрын

    Brilliant video! Thank you very very much!

  • @osmosis

    @osmosis

    Ай бұрын

    You're very welcome! 😊

  • @vaevoe6272
    @vaevoe6272 Жыл бұрын

    my prof has a PhD in neuroscience from harvard and ive listened to him explain this numerous times and never understood it but this video made me understand it finally. ty

  • @osmosis

    @osmosis

    Жыл бұрын

    Wow! We're glad that our video was able to help! 🙏🏼 ❤️ 😊

  • @jessicaparker6626
    @jessicaparker6626Ай бұрын

    I was always taught that the cell's overall resting membrane potential is closer to -70 mV. Can you explain why this value is different that the -86 mV that you calculated? Thank you so much! This video was SO helpful!

  • @patiencechepkorir5596
    @patiencechepkorir55962 жыл бұрын

    This is the best video on membrane potential 😉glad to have discovered this channel 🙂😌

  • @osmosis

    @osmosis

    2 жыл бұрын

    Welcome aboard! Hope you'll also enjoy our other videos! 😊 🙌🏼 🥰

  • @arieltf2788
    @arieltf27886 жыл бұрын

    brilliant brilliant video. Thank you A LOT.

  • @osmosis

    @osmosis

    6 жыл бұрын

    Thank you so much, Arsenic! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J

  • @laurentiu244
    @laurentiu2447 жыл бұрын

    great . thank you

  • @MrTote191
    @MrTote1917 жыл бұрын

    Could you explain what's the role of the Na K pump in calculating the resting membrane potential?

  • @dannichols6261

    @dannichols6261

    4 жыл бұрын

    Yeah, they *don't* explain that at all. They do present some interesting information (ie, ion concentration values). They *mention* the Na K pump, but do *not* explain its role in maintaining membrane potential. Not good! And while they *mention* an 'inward rectifier channel', they don't *explain it* at all!

  • @magranin7319

    @magranin7319

    2 жыл бұрын

    @@dannichols6261 It would be great if they did but I think this video is targeted at people who already have a good understanding of passive and active transport systems. KZread is great, there are a lot of videos that cover that in depth. I would watch them and go back to this one. Hope this helps :)

  • @imperiusss
    @imperiusss7 жыл бұрын

    wow great! Will you guys eventually also do lectures on neuroanatomy/physiology?

  • @greenapplejuice23

    @greenapplejuice23

    7 жыл бұрын

    we dont fuck with that shit. We are going in on female vag anatomy next!!

  • @osmosis

    @osmosis

    7 жыл бұрын

    We're mostly focusing on pathology still, for now.

  • @meharabchoudhury38
    @meharabchoudhury386 жыл бұрын

    Including the constant field equation would be useful here!

  • @MrBeachwaves
    @MrBeachwaves4 жыл бұрын

    Thanks for another great video! Would have preferred a more conceptual rather than a mathematical explanation though, as well as an explanation of the role of the NaKATP pump and its contribution to the resting membrane potential.

  • @dannichols6261

    @dannichols6261

    4 жыл бұрын

    Yes, I agree, it's not so good to just *mention* the Na/K pump, and then say nothing *about* it! I think it simplifies to: the Na/K pump helps maintain the *concentration gradient* , while the *leak channels*, in relation to *both* the concentration gradient *and* the (sort-of opposing) electrostatic gradient, are what balance out to yield the resting membrane potential.

  • @brendaloaiza790
    @brendaloaiza790 Жыл бұрын

    wonderful explained thank you!

  • @osmosis

    @osmosis

    Жыл бұрын

    You're very welcome, Brenda! 🥰❤️🙏🏼

  • @nanak3363
    @nanak33637 жыл бұрын

    Thank u :)

  • @jethureddy2426
    @jethureddy24267 жыл бұрын

    Excellent!😍 It would really means a lot and nice if you guys upload dailyy one video consecutively!please.......!!!!

  • @osmosis

    @osmosis

    7 жыл бұрын

    We wish we could! Right now we don't have the funding to do that, but we hope one day we will!

  • @eunbii01
    @eunbii014 жыл бұрын

    this is the best vid ever

  • @sevgilikitaplarm4364
    @sevgilikitaplarm436427 күн бұрын

    This was really helpful.

  • @osmosis

    @osmosis

    24 күн бұрын

    That's nice to know! 💕

  • @raniamalkawi8736
    @raniamalkawi87367 жыл бұрын

    Thanks , when k+ move to outsid by channel , are the particles of Na+ inter in the same time !? and How it do that , by diffusion!? what is name the process in which particles move from low concentration To highe concentration?!

  • @anujachopda5443
    @anujachopda54434 жыл бұрын

    Great video

  • @rajanibuddappagari4682
    @rajanibuddappagari46824 жыл бұрын

    Very nice video sir , but generally why potassium is more transferred to out side?

  • @muzammilashraf9426
    @muzammilashraf94265 жыл бұрын

    want to ask that in guyton the equation has inside/ outside but the equation in video is shows outside/inside. kindly guide me with this thing.

  • @ayesharehman4160
    @ayesharehman41602 жыл бұрын

    This helps me to understand the topic better.✌

  • @osmosis

    @osmosis

    2 жыл бұрын

    We're glad our video was able to help, Ayesha! Thanks for letting us know! 🥰

  • @BoshraAsadi-jx2gc
    @BoshraAsadi-jx2gc2 ай бұрын

    Thank you so much. 2024 and video is one of the most helpful lessons 😍😍😍

  • @osmosis

    @osmosis

    2 ай бұрын

    Glad it was helpful! ❤️

  • @mustafamohamaed9764
    @mustafamohamaed9764 Жыл бұрын

    very well explained, Great Job ☺☺

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks, Mustafa! 😊

  • @fox2splash127
    @fox2splash1272 жыл бұрын

    hi.. can u explain the resting membrane potential during cardiac surgery.. the usage of cardioplegia to stop the heart..

  • @rababbashir78
    @rababbashir783 жыл бұрын

    You really deserve subscription

  • @osmosis

    @osmosis

    3 жыл бұрын

    Thanks for this feedback!

  • @harryshaw5360
    @harryshaw53605 жыл бұрын

    Very useful :)

  • @zainabsh629
    @zainabsh6295 жыл бұрын

    is there a vedio for donnan membrane equilibrium

  • @zeenazeena56
    @zeenazeena56 Жыл бұрын

    Thank you so much, i finally understood this 🥳

  • @osmosis

    @osmosis

    Жыл бұрын

    Glad it helped! ❤️

  • @LittleBear2007
    @LittleBear20074 жыл бұрын

    I want to get a really high usmle. Do you have a strategy for that?

  • @rollietocups8592
    @rollietocups85927 жыл бұрын

    curious: is this true across all of life? Same for bacteria, plants, fungi?

  • @ZaynabAhmed-vf7fd
    @ZaynabAhmed-vf7fd4 ай бұрын

    you're the best, explained it better than my uni professors

  • @osmosis

    @osmosis

    3 ай бұрын

    Thanks for the feedback! 🙌🏼

  • @BTSARMY-sb8sh
    @BTSARMY-sb8sh2 жыл бұрын

    THANK YOU SO MUCH 💜 SO HELPFUL 💜🥺💜💜💜 THANK U 😭💘💜💜

  • @osmosis

    @osmosis

    2 жыл бұрын

    You're so welcome!

  • @rikkifrank5681
    @rikkifrank56814 жыл бұрын

    I have a way better grasp on this now ty

  • @drpoojasau9974
    @drpoojasau99746 жыл бұрын

    Very nice

  • @liethsaqer376
    @liethsaqer376 Жыл бұрын

    Great work

  • @osmosis

    @osmosis

    Жыл бұрын

    Thanks! ❤️

  • @hyunjinlee6696
    @hyunjinlee66962 ай бұрын

    awesome

  • @dinaalbushra5364
    @dinaalbushra53642 жыл бұрын

    Thaankkkk uuuu♥️♥️

  • @masudsiddique8034
    @masudsiddique80347 жыл бұрын

    Please upload a video on DIC disseminated intravascular coagulation

  • @osmosis

    @osmosis

    7 жыл бұрын

    We will eventually! You can vote for upcoming videos by becoming a Patreon subscriber. www.patreon.com/osmosis

  • @jackt6110
    @jackt61103 жыл бұрын

    Thanks for the video, good work!

  • @layapv6471
    @layapv64715 жыл бұрын

    Thank u

  • @spectroxis6418
    @spectroxis64189 ай бұрын

    One thing I’d like to add to this is permeability. At rest without any voltage propagating(action potential) the cell is very permeable to potassium so the summation of these will decrease the effect of calcium, sodium, and chloride a lot and only affect the potassium slightly. GHK equation

  • @minggu6908
    @minggu6908 Жыл бұрын

    are the values of each ions here constant?

  • @jacobnutter1639
    @jacobnutter16395 жыл бұрын

    I may just pass PT school because of you sir

  • @jamasubhankulov5237
    @jamasubhankulov52374 жыл бұрын

    Could anyone explain me from where 61,5 comes in 4:40 ?

  • @user-fv7dr1cw9z
    @user-fv7dr1cw9z6 ай бұрын

    you explain good, and understandable mostly, just all of them number towards the end is a lot and a lil confusing

  • @merajuddinchauhanrajput.6103
    @merajuddinchauhanrajput.61033 жыл бұрын

    Good

  • @ninac2696
    @ninac26965 ай бұрын

    I UNDERSTAND NOW!

  • @JackDoodly
    @JackDoodly2 жыл бұрын

    isn' t the nerst forlmula with an ln and not a log? because thats what i am learning

  • @waledabdelbary4042
    @waledabdelbary40425 жыл бұрын

    I love this vedio

  • @anne-sophiepattijn8302
    @anne-sophiepattijn8302 Жыл бұрын

    When calculating the membrane potential for when the membrane is permeable to multiple ions, why is it that when I do the Goldman equation using the information in your video I get -83mV rather than what you got which was -86mV? I did this: Vm = -61.5 x log( ((150 x 0.9) + (10 x 0.01) + (0.001 x 0.01) + (103 x 0.08)) / ((5 x 0.9) + (142 x 0.01) + (5 x 0.01) + (4 x 0.08)) ) = -83mV

  • @vadymtrokhymchuk2615
    @vadymtrokhymchuk26152 жыл бұрын

    Inward rectifier K+ channels pump K+ to inside! Not like leak K+ channels that allow to go to outside

  • @maiatwa814
    @maiatwa8144 жыл бұрын

    Why CL is more concentrated outside the cell than inside??? Plz

  • @dylanstevens4589
    @dylanstevens45893 жыл бұрын

    The first calculation for Potassium is incorrect. It should be -82.8 and not -81.0 as stated in the video.

  • @Ani.DR.07
    @Ani.DR.077 жыл бұрын

    EXcellent guys. but why such vague jumping from one topic to other all of a sudden?

  • @greenapplejuice23
    @greenapplejuice237 жыл бұрын

    i got screwed on my boards regarding this when i got my bachelor's in patient transporter

  • @ahmadmansour521
    @ahmadmansour5214 жыл бұрын

    If K+ gets in through electrostatic gradient what Is the benefit of pump then its confusing

  • @niyathicm6549
    @niyathicm65494 жыл бұрын

    greatt