Resting membrane potential - definition, examples
What is the resting membrane potential? The cell's resting membrane potential is the electric potential of the cell, and exists as a result of ions moving into and out of the cell. This video covers the definition of resting membrane potential, as well as how to calculate it using the Nernst equation. Find our full video library only on Osmosis: osms.it/more.
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Пікірлер: 185
best video I've seen on ionic basis of resting potentials! thank you, I've been searching and this one is the easiest to follow along and explains the equations/gradients the best
This is amazing!! I'm have zero intuition for biophysiology but you made it as clear as glass. Thanks for breaking it down into baby steps!! Love your simple but comprehensive diagrams.
Great, I had been waiting on Physiology from Osmosis for a long time! Thank you!
Wow, you make everything SO simple. i was stuck on a couple concepts here, clear 100%!
osmosis! this video is brilliant !! I've read about this topic from endless sources but I've never felt until now that I've truly grasped the concept. Thank you so much for your work. I've watched at least 90% of your pathology videos and honestly After Robbins and Porth you have made my life so much easier! thank you
@osmosis
7 жыл бұрын
Thanks so much! It would be awesome if you and your friends could review us on our Facebook page. facebook.com/pg/OsmoseIt
wow!!! super clear, feel so good watching this!!
I find your Osmosis is so clear and easy to remember. I want to be a part of your osmosis. Can't i?
You made it quite clear! Thanks!
this is the second time for me watching this, just wanted to say THANK YOU!!!
Its really great understand! Thanks for making awesome video.
Thank you, this was VERY helpful! ^_^ Loved it.
Clear as crystal, thanks!
This video seemed so simple, I was brand new to this formula a couple of weeks ago. So I kept watching it, but once i slowed the speed right down - then it started kicking in! thank you so much!
@osmosis
Жыл бұрын
Most welcome! 😊
That was a great piece of work!
@gunnerprinceton9726
3 жыл бұрын
pro trick : watch series on flixzone. I've been using them for watching all kinds of movies these days.
@arthurwesley7444
3 жыл бұрын
@Gunner Princeton Yea, have been using flixzone} for since november myself :D
@judahcallum8504
3 жыл бұрын
@Gunner Princeton yea, I've been watching on flixzone} for since december myself :)
Thank you this is soo helpful
Great video ! thank you again Osmosis
This was really well done!
Very good explanation, keep posting videos like this :D
woww you start physio, Thank of billions...
Really amazing ........iam really appreciate your great and fruitful work....thanks🙏
It is the nicest video i've ever watched !! Thank u :*)
Unexplainable!!! Unbelievable!!! Thanks🤗🤗🤗
Only video across globe that clearly explains resting membrane potential and equilibrium potential. Thank you sir 😊
@osmosis
7 ай бұрын
Happy to help 💖
that was useful thankyou please do more physiology videos I'll be grateful for that
Very helpful thank you! Its hard teaching yourself this when you are taking online classes because of this quarentine
@shashankpahariya
4 жыл бұрын
Hii
I lkie the way he explains and the presentation is always very nice to watch n clear .
@osmosis
6 жыл бұрын
Thanks, Neha! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J
for the first time i understood. thank you.
thank you for this clear explanation!! i have subscribed to your channel and will definitely explore more!!!
@osmosis
2 жыл бұрын
Hi Tengku! Glad you enjoy our video! Hope you'll like our other videos too! ❤️
very helpful ! thank u
Woow!! Thank you so much for this video!! Awsome explanation
@osmosis
7 жыл бұрын
Thank you, Leticia! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J
Thanks you saved me a lot of time.
Thank you so much, I wish I found this prior to the test. I would have got these answers right. Damn>
This helped SO MUCH, especially during COVD-19 where learning things on your own from the university is a bit more difficult to understand on your own, when someone is not lecturing these bulky ideas to you. Great Video!
@nzzuraki991
4 жыл бұрын
Erik Plumeda so true
this was so clear and helpful. thank you!
Great physiology
So good. Thanx a lot!
THANK YOU. Explained it really well mate!
Physiology! Great!
i never understood the resting memb. potential but now ... i still don't understand it
@samiras6962
5 жыл бұрын
mohammed just memorize it 🤷🏽♀️
@Apratim98
5 жыл бұрын
I know its fucking confusing, bcoz no one is starting it frm the basic, i have made video too on the same topic, watch it once i hope it will help you..and pls comment if it does..or any doubt..
@rania7801
5 жыл бұрын
@@Apratim98 Thank you! I just checked out your video and it was really helpful! Thankfully I checked the replies.
@sabett198x
5 жыл бұрын
Lol, We are on the same boat Mohammed... and I can’t memorize something that I don’t have a basic understanding of...
@aleidaortiz4599
4 жыл бұрын
Me too
excellent, excellent video! I was wondering though, why was the calcium +2 intracellular concentration was not 0.0001? in the video it is listed as 0.001
Awesome content and i like it so much :DDD
This video is amazing. I am studying bilogical psychology, and the book didnt give me a clear picture of what this process looked like. Amazing stuff!
@osmosis
Жыл бұрын
Wow, thanks for the feedback! 💕
THANK YOU!
this is so great, the book i used just glances over most of this to jump to the action potentail. and i was struggeling to understand how the consentration and charges worked.
@osmosis
5 ай бұрын
Thanks! 🙏🏼
Brilliant video! Thank you very very much!
@osmosis
Ай бұрын
You're very welcome! 😊
my prof has a PhD in neuroscience from harvard and ive listened to him explain this numerous times and never understood it but this video made me understand it finally. ty
@osmosis
Жыл бұрын
Wow! We're glad that our video was able to help! 🙏🏼 ❤️ 😊
I was always taught that the cell's overall resting membrane potential is closer to -70 mV. Can you explain why this value is different that the -86 mV that you calculated? Thank you so much! This video was SO helpful!
This is the best video on membrane potential 😉glad to have discovered this channel 🙂😌
@osmosis
2 жыл бұрын
Welcome aboard! Hope you'll also enjoy our other videos! 😊 🙌🏼 🥰
brilliant brilliant video. Thank you A LOT.
@osmosis
6 жыл бұрын
Thank you so much, Arsenic! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on KZread? Check it out here: bit.ly/2u35D6J
great . thank you
Could you explain what's the role of the Na K pump in calculating the resting membrane potential?
@dannichols6261
4 жыл бұрын
Yeah, they *don't* explain that at all. They do present some interesting information (ie, ion concentration values). They *mention* the Na K pump, but do *not* explain its role in maintaining membrane potential. Not good! And while they *mention* an 'inward rectifier channel', they don't *explain it* at all!
@magranin7319
2 жыл бұрын
@@dannichols6261 It would be great if they did but I think this video is targeted at people who already have a good understanding of passive and active transport systems. KZread is great, there are a lot of videos that cover that in depth. I would watch them and go back to this one. Hope this helps :)
wow great! Will you guys eventually also do lectures on neuroanatomy/physiology?
@greenapplejuice23
7 жыл бұрын
we dont fuck with that shit. We are going in on female vag anatomy next!!
@osmosis
7 жыл бұрын
We're mostly focusing on pathology still, for now.
Including the constant field equation would be useful here!
Thanks for another great video! Would have preferred a more conceptual rather than a mathematical explanation though, as well as an explanation of the role of the NaKATP pump and its contribution to the resting membrane potential.
@dannichols6261
4 жыл бұрын
Yes, I agree, it's not so good to just *mention* the Na/K pump, and then say nothing *about* it! I think it simplifies to: the Na/K pump helps maintain the *concentration gradient* , while the *leak channels*, in relation to *both* the concentration gradient *and* the (sort-of opposing) electrostatic gradient, are what balance out to yield the resting membrane potential.
wonderful explained thank you!
@osmosis
Жыл бұрын
You're very welcome, Brenda! 🥰❤️🙏🏼
Thank u :)
Excellent!😍 It would really means a lot and nice if you guys upload dailyy one video consecutively!please.......!!!!
@osmosis
7 жыл бұрын
We wish we could! Right now we don't have the funding to do that, but we hope one day we will!
this is the best vid ever
This was really helpful.
@osmosis
24 күн бұрын
That's nice to know! 💕
Thanks , when k+ move to outsid by channel , are the particles of Na+ inter in the same time !? and How it do that , by diffusion!? what is name the process in which particles move from low concentration To highe concentration?!
Great video
Very nice video sir , but generally why potassium is more transferred to out side?
want to ask that in guyton the equation has inside/ outside but the equation in video is shows outside/inside. kindly guide me with this thing.
This helps me to understand the topic better.✌
@osmosis
2 жыл бұрын
We're glad our video was able to help, Ayesha! Thanks for letting us know! 🥰
Thank you so much. 2024 and video is one of the most helpful lessons 😍😍😍
@osmosis
2 ай бұрын
Glad it was helpful! ❤️
very well explained, Great Job ☺☺
@osmosis
Жыл бұрын
Thanks, Mustafa! 😊
hi.. can u explain the resting membrane potential during cardiac surgery.. the usage of cardioplegia to stop the heart..
You really deserve subscription
@osmosis
3 жыл бұрын
Thanks for this feedback!
Very useful :)
is there a vedio for donnan membrane equilibrium
Thank you so much, i finally understood this 🥳
@osmosis
Жыл бұрын
Glad it helped! ❤️
I want to get a really high usmle. Do you have a strategy for that?
curious: is this true across all of life? Same for bacteria, plants, fungi?
you're the best, explained it better than my uni professors
@osmosis
3 ай бұрын
Thanks for the feedback! 🙌🏼
THANK YOU SO MUCH 💜 SO HELPFUL 💜🥺💜💜💜 THANK U 😭💘💜💜
@osmosis
2 жыл бұрын
You're so welcome!
I have a way better grasp on this now ty
Very nice
Great work
@osmosis
Жыл бұрын
Thanks! ❤️
awesome
Thaankkkk uuuu♥️♥️
Please upload a video on DIC disseminated intravascular coagulation
@osmosis
7 жыл бұрын
We will eventually! You can vote for upcoming videos by becoming a Patreon subscriber. www.patreon.com/osmosis
Thanks for the video, good work!
Thank u
One thing I’d like to add to this is permeability. At rest without any voltage propagating(action potential) the cell is very permeable to potassium so the summation of these will decrease the effect of calcium, sodium, and chloride a lot and only affect the potassium slightly. GHK equation
are the values of each ions here constant?
I may just pass PT school because of you sir
Could anyone explain me from where 61,5 comes in 4:40 ?
you explain good, and understandable mostly, just all of them number towards the end is a lot and a lil confusing
Good
I UNDERSTAND NOW!
isn' t the nerst forlmula with an ln and not a log? because thats what i am learning
I love this vedio
When calculating the membrane potential for when the membrane is permeable to multiple ions, why is it that when I do the Goldman equation using the information in your video I get -83mV rather than what you got which was -86mV? I did this: Vm = -61.5 x log( ((150 x 0.9) + (10 x 0.01) + (0.001 x 0.01) + (103 x 0.08)) / ((5 x 0.9) + (142 x 0.01) + (5 x 0.01) + (4 x 0.08)) ) = -83mV
Inward rectifier K+ channels pump K+ to inside! Not like leak K+ channels that allow to go to outside
Why CL is more concentrated outside the cell than inside??? Plz
The first calculation for Potassium is incorrect. It should be -82.8 and not -81.0 as stated in the video.
EXcellent guys. but why such vague jumping from one topic to other all of a sudden?
i got screwed on my boards regarding this when i got my bachelor's in patient transporter
If K+ gets in through electrostatic gradient what Is the benefit of pump then its confusing
greatt